acetaminophen has been researched along with Asymmetric Diabetic Proximal Motor Neuropathy in 15 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compared the efficacy and safety of tramadol/acetaminophen (T/A) and gabapentin in the management of painful diabetic neuropathy." | 9.14 | Comparison of the efficacy and safety of tramadol/acetaminophen combination therapy and gabapentin in the treatment of painful diabetic neuropathy. ( Baik, SH; Cha, BY; Kim, CH; Kim, DS; Ko, KS; Ko, SH; Kwon, HS; Lee, JH; Mok, JO; Noh, JH; Park, IB; Park, TS; Son, HS; Yu, JM, 2010) |
| "This study compared the efficacy and safety of tramadol/acetaminophen (T/A) and gabapentin in the management of painful diabetic neuropathy." | 5.14 | Comparison of the efficacy and safety of tramadol/acetaminophen combination therapy and gabapentin in the treatment of painful diabetic neuropathy. ( Baik, SH; Cha, BY; Kim, CH; Kim, DS; Ko, KS; Ko, SH; Kwon, HS; Lee, JH; Mok, JO; Noh, JH; Park, IB; Park, TS; Son, HS; Yu, JM, 2010) |
| " the proportional cumulative area under the curve of paracetamol) was utilized in diabetic patients in order to detect both gastroparesis and the influence of metoclopramide, a known prokinetic drug, on this condition." | 5.08 | The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis. ( Moncrieff, J; Snyman, JR; Sommers, DK; van Wyk, M, 1995) |
| "Tramadol/APAP was associated with significantly greater improvement than placebo (p < or = 0." | 2.73 | Randomized study of tramadol/acetaminophen versus placebo in painful diabetic peripheral neuropathy. ( Freeman, R; Hewitt, DJ; Jordan, DM; Raskin, P; Rosenthal, NR; Vorsanger, GJ; Xiang, J, 2007) |
| "Amitriptyline was the only antidepressant prescribed commonly as a first-line treatment." | 1.39 | An observational descriptive study of the epidemiology and treatment of neuropathic pain in a UK general population. ( Carroll, D; Gabriel, ZL; Hall, GC; McQuay, HJ; Morant, SV, 2013) |
| "Patients were classified as diabetic autonomic neuropathy positive or negative using five standardized haemodynamic reflex tests." | 1.31 | Evaluation of standard haemodynamic tests of autonomic function and HbA1c as predictors of delayed gastric emptying in patients with type 1 diabetes mellitus. ( Cooke, T; Duggan, PF; Lydon, A; Murray, C; O'Halloran, D; Shorten, GD, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hall, GC | 1 |
| Morant, SV | 1 |
| Carroll, D | 1 |
| Gabriel, ZL | 1 |
| McQuay, HJ | 1 |
| Micov, A | 1 |
| Tomić, M | 1 |
| Pecikoza, U | 1 |
| Ugrešić, N | 1 |
| Stepanović-Petrović, R | 1 |
| Déciga-Campos, M | 1 |
| Ortíz-Andrade, R | 1 |
| Zirakzadeh, A | 1 |
| Herlein, A | 1 |
| Groß, MA | 1 |
| Mereiter, K | 1 |
| Wang, Y | 1 |
| Weissensteiner, W | 1 |
| Cuaderes, E | 1 |
| DeShea, L | 1 |
| Lamb, WL | 1 |
| Yamada, T | 1 |
| Takasu, A | 1 |
| Vijayan, A | 1 |
| Li, T | 1 |
| Dusso, A | 1 |
| Jain, S | 1 |
| Coyne, DW | 1 |
| Ben Saad, H | 1 |
| Driss, D | 1 |
| Ben Amara, I | 1 |
| Boudawara, O | 1 |
| Boudawara, T | 1 |
| Ellouz Chaabouni, S | 1 |
| Mounir Zeghal, K | 1 |
| Hakim, A | 1 |
| Zhou, Y | 1 |
| Prediger, P | 1 |
| Dias, LC | 1 |
| Murphy, AC | 1 |
| Leadlay, PF | 1 |
| Puillandre, N | 1 |
| Duda, TF | 1 |
| Meyer, C | 1 |
| Olivera, BM | 1 |
| Bouchet, P | 1 |
| Vermang, B | 1 |
| Wätjen, JT | 1 |
| Fjällström, V | 1 |
| Rostvall, F | 1 |
| Edoff, M | 1 |
| Kotipalli, R | 1 |
| Henry, F | 1 |
| Flandre, D | 1 |
| Hamilton, ER | 1 |
| Samek, DR | 1 |
| Keyes, M | 1 |
| McGue, MK | 1 |
| Iacono, WG | 1 |
| Valcour, A | 1 |
| Zierold, C | 1 |
| Podgorski, AL | 1 |
| Olson, GT | 1 |
| Wall, JV | 1 |
| DeLuca, HF | 1 |
| Bonelli, F | 1 |
| Morton, TL | 1 |
| Devarakonda, K | 1 |
| Kostenbader, K | 1 |
| Montgomery, J | 1 |
| Barrett, T | 1 |
| Webster, L | 1 |
| Miltiades, P | 1 |
| Lamprianidou, E | 1 |
| Kerzeli, IK | 1 |
| Nakou, E | 1 |
| Papamichos, SI | 1 |
| Spanoudakis, E | 1 |
| Kotsianidis, I | 1 |
| Rahbar, MH | 1 |
| Samms-Vaughan, M | 1 |
| Ma, J | 1 |
| Bressler, J | 1 |
| Dickerson, AS | 1 |
| Hessabi, M | 1 |
| Loveland, KA | 1 |
| Grove, ML | 1 |
| Shakespeare-Pellington, S | 1 |
| Beecher, C | 1 |
| McLaughlin, W | 1 |
| Boerwinkle, E | 1 |
| Fujisawa, Y | 1 |
| Napoli, E | 1 |
| Wong, S | 1 |
| Song, G | 1 |
| Yamaguchi, R | 1 |
| Matsui, T | 1 |
| Nagasaki, K | 1 |
| Ogata, T | 1 |
| Giulivi, C | 1 |
| Pietrzycka, A | 1 |
| Kózka, M | 1 |
| Urbanek, T | 1 |
| Stpniewski, M | 1 |
| Kucharzewski, M | 1 |
| Huang, TQ | 1 |
| Zou, MX | 1 |
| Pasek, DA | 1 |
| Meissner, G | 1 |
| Hersey, SP | 1 |
| Garland, RM | 1 |
| Crosbie, E | 1 |
| Shingler, T | 1 |
| Sorooshian, A | 1 |
| Piketh, S | 1 |
| Burger, R | 1 |
| Chang, LC | 1 |
| Yue, J | 1 |
| Wang, W | 1 |
| Wu, Q | 1 |
| Meier, RR | 1 |
| Han, L | 1 |
| Jia, Y | 1 |
| Song, Q | 1 |
| Wang, N | 1 |
| Wang, J | 1 |
| Bai, B | 1 |
| Chen, X | 1 |
| Wang, C | 1 |
| Cheng, Y | 1 |
| Kim, MH | 1 |
| Lee, YS | 1 |
| Lee, MS | 1 |
| Anderson, LG | 1 |
| Dunn, AM | 1 |
| Rosewarne, PJ | 1 |
| Stebbing, PD | 1 |
| Nicolas, F | 1 |
| Wu, C | 1 |
| Bukhari, S | 1 |
| de Toledo, SM | 1 |
| Li, H | 1 |
| Shibata, M | 1 |
| Azzam, EI | 1 |
| Smucny, J | 1 |
| Stevens, KE | 1 |
| Tregellas, JR | 1 |
| Karuppuchamy, S | 1 |
| Brundha, C | 1 |
| Wilkens, MR | 1 |
| Maté, LM | 1 |
| Schnepel, N | 1 |
| Klinger, S | 1 |
| Muscher-Banse, AS | 1 |
| Ballent, M | 1 |
| Virkel, G | 1 |
| Lifschitz, AL | 1 |
| Simpson, RW | 1 |
| Wlodarczyk, JH | 1 |
| Ko, SH | 1 |
| Kwon, HS | 1 |
| Yu, JM | 1 |
| Baik, SH | 1 |
| Park, IB | 1 |
| Lee, JH | 1 |
| Ko, KS | 1 |
| Noh, JH | 1 |
| Kim, DS | 1 |
| Kim, CH | 1 |
| Mok, JO | 1 |
| Park, TS | 1 |
| Son, HS | 1 |
| Cha, BY | 1 |
| Gong, YH | 1 |
| Yu, XR | 1 |
| Liu, HL | 1 |
| Yang, N | 1 |
| Zuo, PP | 1 |
| Huang, YG | 1 |
| Wernicke, JF | 2 |
| Pritchett, YL | 2 |
| D'Souza, DN | 2 |
| Waninger, A | 1 |
| Tran, P | 1 |
| Iyengar, S | 2 |
| Raskin, J | 2 |
| Freeman, R | 1 |
| Raskin, P | 1 |
| Hewitt, DJ | 1 |
| Vorsanger, GJ | 1 |
| Jordan, DM | 1 |
| Xiang, J | 1 |
| Rosenthal, NR | 1 |
| Wang, F | 1 |
| Smith, TR | 1 |
| Chappell, AS | 1 |
| Danilov, AB | 1 |
| Zharkova, TR | 1 |
| van Wyk, M | 1 |
| Sommers, DK | 1 |
| Snyman, JR | 1 |
| Moncrieff, J | 1 |
| Feng, B | 1 |
| Li, Y | 1 |
| Li, C | 1 |
| Lydon, A | 1 |
| Murray, C | 1 |
| Cooke, T | 1 |
| Duggan, PF | 1 |
| O'Halloran, D | 1 |
| Shorten, GD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Pregabalin and Duloxetine in Patients With Painful Diabetic Peripheral Neuropathy (PDPN): the Effect of Pain on Cognitive Function, Sleep and Quality of Life (BLOSSOM)[NCT04246619] | Phase 4 | 254 participants (Actual) | Interventional | 2019-11-12 | Terminated (stopped due to The statistical analysis will still provide relevant results with the same statistical power as initially planned.COVID-19 pandemic prolonged the recruiting period and consequently affected the costs of the clinical trial.) | ||
| A Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Tramadol HCl/Acetaminophen for the Treatment of Painful Diabetic Neuropathy[NCT00210847] | Phase 3 | 313 participants (Actual) | Interventional | 2003-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for acetaminophen and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Advanced Oxidation Protein Products; Aged; A | 2015 |
Transdermal Buprenorphine Relieves Neuropathic Pain: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial in Diabetic Peripheral Neuropathic Pain.
Topics: Acetaminophen; Administration, Cutaneous; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; | 2016 |
Comparison of the efficacy and safety of tramadol/acetaminophen combination therapy and gabapentin in the treatment of painful diabetic neuropathy.
Topics: Acetaminophen; Adult; Aged; Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Diabetes Mellit | 2010 |
A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain.
Topics: Acetaminophen; Adrenergic Uptake Inhibitors; Aged; Analgesics, Non-Narcotic; Diabetic Neuropathies; | 2006 |
Randomized study of tramadol/acetaminophen versus placebo in painful diabetic peripheral neuropathy.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Diab | 2007 |
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.
Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathi | 2007 |
The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Diabetes Mellitus, Type 1; Diabetic Neuropathi | 1995 |
8 other studies available for acetaminophen and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
An observational descriptive study of the epidemiology and treatment of neuropathic pain in a UK general population.
Topics: Acetaminophen; Adolescent; Adult; Aged; Amines; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, | 2013 |
Levetiracetam synergises with common analgesics in producing antinociception in a mouse model of painful diabetic neuropathy.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Diabetic Neuropathies; Dose-Response Relationship, Drug | 2015 |
Enhancement of Antihyperalgesia by the Coadministration of N-palmitoylethanolamide and Acetaminophen in Diabetic Rats.
Topics: Acetaminophen; Amides; Analgesics; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; | 2015 |
Antinociceptive effects of combination of tramadol and acetaminophen on painful diabetic neuropathy in streptozotocin-induced diabetic rats.
Topics: Acetaminophen; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Therapy, Combin | 2011 |
[Pharmacotherapy with zaldiar of the pain syndrome in diabetic polyneuropathy].
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Diab | 2007 |
[Acetaminophen absorption test for determination of diabetic gastroparesis and effects of erythromycin on gastric emptying].
Topics: Absorption; Acetaminophen; Diabetes Complications; Diabetic Neuropathies; Erythromycin; Female; Gast | 1996 |
Drugs for pain.
Topics: Acetaminophen; Administration, Oral; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics | 1998 |
Evaluation of standard haemodynamic tests of autonomic function and HbA1c as predictors of delayed gastric emptying in patients with type 1 diabetes mellitus.
Topics: Absorption; Acetaminophen; Analgesics, Non-Narcotic; Area Under Curve; Autonomic Nervous System; Aut | 2000 |