Page last updated: 2024-10-21

acetaminophen and Astrocytoma

acetaminophen has been researched along with Astrocytoma in 3 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
"Acetophenetidines, acetamidophenols, phenetidines and aminophenols substituted in o-, m- or p-position inhibit prostaglandin-synthetases originating from C 1300 mouse neuroblastoma cells (clone N2A), rat astrocytoma cells (clone C 6) and rat renal medulla."3.66Inhibition of prostaglandin synthetases derived from neuronal and glial cells and rat renal medulla by ortho-, meta- and para-substituted aminophenolic compounds. ( Baumann, J; von Bruchhausen, F; Wurm, G, 1983)
"The inhibitory actions of phenacetin and paracetamol and of their desacetylation products on prostaglandin synthesis were studied on enzyme preparations originating from a neuronal cell line (mouse neuroblastoma, clone N2A), a glial cell line (rat astrocytoma, clone C6) and rat renal medulla."3.66Inhibitory actions of desacetylation products of phenacetin and paracetamol on prostaglandin synthetases in neuronal and glial cell lines and rat renal medulla. ( Baumann, J; von Bruchlausen, F, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baumann, J2
von Bruchhausen, F1
Wurm, G1
von Bruchlausen, F1
Landolfi, C1
Soldo, L1
Polenzani, L1
Apicella, C1
Capezzone de Joannon, A1
Coletta, I1
Di Cesare, F1
Brufani, M1
Pinza, M1
Milanese, C1

Other Studies

3 other studies available for acetaminophen and Astrocytoma

ArticleYear
Inhibition of prostaglandin synthetases derived from neuronal and glial cells and rat renal medulla by ortho-, meta- and para-substituted aminophenolic compounds.
    Prostaglandins, leukotrienes, and medicine, 1983, Volume: 10, Issue:3

    Topics: Acetaminophen; Aminophenols; Animals; Aspirin; Astrocytoma; Cell Line; Clone Cells; Cyclooxygenase I

1983
Inhibitory actions of desacetylation products of phenacetin and paracetamol on prostaglandin synthetases in neuronal and glial cell lines and rat renal medulla.
    Life sciences, 1982, May-24, Volume: 30, Issue:21

    Topics: Acetaminophen; Aminophenols; Animals; Astrocytoma; Cell Line; Cyclooxygenase Inhibitors; In Vitro Te

1982
Inflammatory molecule release by beta-amyloid-treated T98G astrocytoma cells: role of prostaglandins and modulation by paracetamol.
    European journal of pharmacology, 1998, Oct-30, Volume: 360, Issue:1

    Topics: Acetaminophen; Amyloid beta-Peptides; Analgesics, Non-Narcotic; Astrocytoma; Culture Media, Conditio

1998