Page last updated: 2024-10-22

acetaminophen and Allergic Reaction

acetaminophen has been researched along with Allergic Reaction in 24 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions."9.13A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008)
"Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions."5.13A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008)
"We recently found that paracetamol (acetaminophen) use in late pregnancy was associated with an increased risk of early wheezing in the offspring."3.73Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood. ( Headley, JE; Henderson, AJ; Jones, RW; Newson, RB; Shaheen, SO; Strachan, DP; Stratton, FD, 2005)
"Studies in developed countries suggest that acetaminophen use is associated with increased risk of asthma, but it is unclear whether this association is causal."3.73Use of acetaminophen and the risk of self-reported allergic symptoms and skin sensitization in Butajira, Ethiopia. ( Aref-Adib, G; Berhane, Y; Britton, J; Davey, G; Duncan, P; Venn, A, 2005)
"Rhinitis was associated with a greater number of episodes of night cough in adolescents with asthma."1.46Prevalence of asthma and allergies in 13-14-year-old adolescents from Luanda, Angola. ( Arrais, M; Gama, JMR; Lulua, O; Quifica, F; Rosado-Pinto, J; Taborda-Barata, L, 2017)
" Significant positive dose-response effects of early life use were seen in relation to the prevalence of all outcomes at age 5."1.40Effects of early life paracetamol use on the incidence of allergic disease and sensitization: 5 year follow-up of an Ethiopian birth cohort. ( Amberbir, A; Britton, J; Davey, G; Hanlon, C; Medhin, G; Venn, A, 2014)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's0 (0.00)18.2507
2000's9 (37.50)29.6817
2010's12 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arrais, M1
Lulua, O1
Quifica, F1
Rosado-Pinto, J1
Gama, JMR1
Taborda-Barata, L1
Wurth, M1
Papantonakis, CM1
Nevel, RJ1
Thomas, CS1
Sokolow, AG1
Moore, PE1
Rosas-Salazar, C1
Bennardello, F1
Fidone, C1
Spadola, V1
Cabibbo, S1
Travali, S1
Garozzo, G1
Antolino, A1
Tavolino, G1
Falla, C1
Bonomo, P1
Suárez-Varela, MM1
García-Marcos, L1
Fernández-Espinar, JF1
Bercedo-Sanz, A1
Aguinaga-Ontoso, I1
González-Díaz, C1
Carvajal-Urueña, I1
Busquet-Monge, RM1
Arnedo-Pena, A1
García de Andoin, N1
Batlles-Garrido, J1
Blanco-Quirós, A1
López-Silvarrey Varela, A1
García-Hernández, G1
Gimeno-Clemente, N1
Rubio-López, N1
Llopis-González, A1
Amberbir, A1
Medhin, G1
Hanlon, C1
Britton, J2
Davey, G2
Venn, A2
Duran, J1
Siddique, S1
Cleary, M1
Kennedy, LD1
Case, LD1
Hurd, DD1
Cruz, JM1
Pomper, GJ1
Martí-Carvajal, AJ1
Solà, I1
González, LE1
Leon de Gonzalez, G1
Rodriguez-Malagon, N1
Wennergren, G1
Bakkeheim, E1
Mowinckel, P1
Carlsen, KH1
Håland, G1
Carlsen, KC1
Andabaka, T1
Globočnik, T1
Vukelić, D1
Esposito, S1
Baršić, B1
Holt, PG1
Strickland, DH1
Sly, PD1
Källén, B1
Finnström, O1
Nygren, KG1
Otterblad Olausson, P1
LOZINSKI, E1
Shaheen, SO2
Newson, RB2
Henderson, AJ1
Headley, JE1
Stratton, FD1
Jones, RW1
Strachan, DP1
Sanders, RP1
Maddirala, SD1
Geiger, TL2
Pounds, S1
Sandlund, JT1
Ribeiro, RC1
Pui, CH1
Howard, SC2
Berhane, Y1
Duncan, P1
Aref-Adib, G1
Allmers, H1
Koniman, R1
Chan, YH1
Tan, TN1
Van Bever, HP1
Chinn, S1
Burney, PG1
Rumack, BH1
Delaney, JC1

Reviews

5 reviews available for acetaminophen and Allergic Reaction

ArticleYear
Effects of Leukoreduction and Premedication With Acetaminophen and Diphenhydramine in Minimizing Febrile Nonhemolytic Transfusion Reactions and Allergic Transfusion Reactions During and After Blood Product Administration: A Literature Review With Recommen
    Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses, 2014, Volume: 31, Issue:4

    Topics: Acetaminophen; Diphenhydramine; Drug Administration Schedule; Erythrocyte Transfusion; Evidence-Base

2014
Pharmacological interventions for the prevention of allergic and febrile non-haemolytic transfusion reactions.
    The Cochrane database of systematic reviews, 2010, Jun-16, Issue:6

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Fever; Histamine H1 Antagon

2010
Virus infection and allergy in the development of asthma: what is the connection?
    Current opinion in allergy and clinical immunology, 2012, Volume: 12, Issue:2

    Topics: Acetaminophen; Asthma; Bacterial Infections; Humans; Hypersensitivity; Interleukin-15; Respiratory T

2012
Frequent acetaminophen use and allergic diseases: is the association clear?
    The Journal of allergy and clinical immunology, 2005, Volume: 116, Issue:4

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Female; Humans; Hypersensit

2005
Acetaminophen and diphenhydramine premedication for allergic and febrile nonhemolytic transfusion reactions: good prophylaxis or bad practice?
    Transfusion medicine reviews, 2007, Volume: 21, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Allergic Agents; Blood Component Transfusion; Diphenhy

2007

Trials

2 trials available for acetaminophen and Allergic Reaction

ArticleYear
The prevention of adverse reactions to transfusions in patients with haemoglobinopathies: a proposed algorithm.
    Blood transfusion = Trasfusione del sangue, 2013, Volume: 11, Issue:3

    Topics: Acetaminophen; Algorithms; Antipyretics; Erythrocyte Transfusion; Female; Follow-Up Studies; Hemoglo

2013
A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions.
    Transfusion, 2008, Volume: 48, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Do

2008

Other Studies

17 other studies available for acetaminophen and Allergic Reaction

ArticleYear
Prevalence of asthma and allergies in 13-14-year-old adolescents from Luanda, Angola.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2017, 06-01, Volume: 21, Issue:6

    Topics: Acetaminophen; Adolescent; Angola; Asthma; Cross-Sectional Studies; Eczema; Female; Humans; Hypersen

2017
Risk Factors Associated with Asthma Development and Control in Children. Mouse Infestation, Antipyretics, Respiratory Viruses, and Allergic Sensitization.
    American journal of respiratory and critical care medicine, 2017, 12-15, Volume: 196, Issue:12

    Topics: Acetaminophen; Allergens; Animals; Antipyretics; Asthma; Child; Humans; Hypersensitivity; Ibuprofen;

2017
Is acetaminophen use associated with atopic eczema and other allergic diseases in adolescents?
    Iranian journal of allergy, asthma, and immunology, 2013, May-15, Volume: 12, Issue:2

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Cross-Sectional Studies; Dermatitis, Atopic; Fe

2013
Effects of early life paracetamol use on the incidence of allergic disease and sensitization: 5 year follow-up of an Ethiopian birth cohort.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Acetaminophen; Age of Onset; Asthma; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Deve

2014
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorpha

2009
Paracetamol – accumulating reports of an association with allergy and asthma.
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:1

    Topics: Acetaminophen; Antipyretics; Asthma; Child; Female; Humans; Hypersensitivity; Infant; Pregnancy; Pre

2011
Paracetamol in early infancy: the risk of childhood allergy and asthma.
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:1

    Topics: Acetaminophen; Asthma; Child; Female; Follow-Up Studies; Humans; Hypersensitivity; Infant; Male; Pre

2011
Parental administration of antipyretics to children with upper respiratory tract infections without consultation with a physician.
    Croatian medical journal, 2011, Volume: 52, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Antipyretics; Child; Child Care; Child Day Care Centers; Child, Pr

2011
Maternal drug use during pregnancy and asthma risk among children.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2013, Volume: 24, Issue:1

    Topics: Acetaminophen; Analgesics, Opioid; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Child; Child

2013
THE COMPARATIVE PHARMACOLOGY.
    Applied therapeutics, 1963, Volume: 5

    Topics: Acetaminophen; Acetanilides; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Blood Coag

1963
Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; As

2005
Premedication with acetaminophen or diphenhydramine for transfusion with leucoreduced blood products in children.
    British journal of haematology, 2005, Volume: 130, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Allergic Agents; Blood Component Removal; Blood Compon

2005
Use of acetaminophen and the risk of self-reported allergic symptoms and skin sensitization in Butajira, Ethiopia.
    The Journal of allergy and clinical immunology, 2005, Volume: 116, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Allergens; Animals; Anti-Inflammatory Age

2005
A matched patient-sibling study on the usage of paracetamol and the subsequent development of allergy and asthma.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2007, Volume: 18, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Child; Child, Preschool; Female; Fetus; Humans; Hyp

2007
Paracetamol sales and atopic disease in children and adults: an ecological analysis.
    The European respiratory journal, 2000, Volume: 16, Issue:5

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Asthma; Child; Drug Utilization; Epidemiologic

2000
Aspirin and acetaminophen.
    Clinical toxicology, 1979, Volume: 15, Issue:3

    Topics: Acetaminophen; Antidotes; Arthritis, Juvenile; Aspirin; Child, Preschool; Female; Hemostasis; Humans

1979
The diagnosis of aspirin idiosyncrasy by analgesic challenge.
    Clinical allergy, 1976, Volume: 6, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Airway Obstruction; Aspirin; Asthma; Drug Hypersensitivity;

1976