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acetaminophen and Alcoholic Hepatitis

acetaminophen has been researched along with Alcoholic Hepatitis in 14 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"The use of intravenous acetylcysteine for off-label indications, specifically non-acetaminophen-induced acute liver failure (NAI-ALF), severe alcoholic hepatitis, and contrast-induced nephropathy (CIN), is reviewed."4.89Intravenous acetylcysteine for indications other than acetaminophen overdose. ( Bass, S; Zook, N, 2013)
" The entire spectrum of alcoholic liver disease, including alcoholic hepatitis, may be perfectly mimicked by severe obesity, diabetes, and perhexiline maleate toxicity."3.67Problems in the necropsy diagnosis of alcoholic liver disease. ( Pounder, DJ, 1984)
"Adult alcohol abusers with a current drinking episode longer than 7 days received either placebo or paracetamol 4 g/day for 5 days."2.75The effects of paracetamol (acetaminophen) on hepatic tests in patients who chronically abuse alcohol - a randomized study. ( Brands, B; Dart, RC; Green, JL; Heard, K; Kuffner, EK; Sproule, B, 2010)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's5 (35.71)18.2507
2000's1 (7.14)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Verdon, I1
Spahr, L1
Serratrice, J1
Bass, S1
Zook, N1
Dart, RC1
Green, JL1
Kuffner, EK1
Heard, K1
Sproule, B1
Brands, B1
Ramaiah, SK1
Jaeschke, H1
Himmelstein, DU1
Woolhandler, SJ1
Adler, RD1
Pounder, DJ1
Meliconi, R1
Perperas, A1
Jensen, D1
Alberti, A1
McFarlane, IG1
Eddleston, AL1
Williams, R2
Hift, RJ1
Spearman, CW1
Lemmer, ER1
Kirsch, RE1
Greminger, S1
Cheng, TJ1
Rex, DK1
Kumar, S1
Harrison, PM1
Wendon, JA1
Gimson, AE1
Alexander, GJ1
Luquel, L1
Azzi, R1
Desaint, B1
Massart, JD1
Offenstadt, G1

Reviews

2 reviews available for acetaminophen and Alcoholic Hepatitis

ArticleYear
Intravenous acetylcysteine for indications other than acetaminophen overdose.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2013, Sep-01, Volume: 70, Issue:17

    Topics: Acetaminophen; Acetylcysteine; Administration, Intravenous; Animals; Antidotes; Drug Overdose; Hepat

2013
Role of neutrophils in the pathogenesis of acute inflammatory liver injury.
    Toxicologic pathology, 2007, Volume: 35, Issue:6

    Topics: Acetaminophen; Acute Disease; Animals; Cell Adhesion; Cell Movement; Hepatitis, Alcoholic; Humans; I

2007

Trials

2 trials available for acetaminophen and Alcoholic Hepatitis

ArticleYear
The effects of paracetamol (acetaminophen) on hepatic tests in patients who chronically abuse alcohol - a randomized study.
    Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:3

    Topics: Acetaminophen; Adult; Aged; Alcoholism; Analgesics, Non-Narcotic; Double-Blind Method; Female; Gluta

2010
Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure.
    The New England journal of medicine, 1991, Jun-27, Volume: 324, Issue:26

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Biological Transport; Chemical and Drug Induced Li

1991

Other Studies

10 other studies available for acetaminophen and Alcoholic Hepatitis

ArticleYear
[N-acetylcysteine : effective treatment in severe alcoholic hepatitis ?]
    Revue medicale suisse, 2018, Jan-17, Volume: 14, Issue:590

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antiviral Agents; Drug Overdose; Hepatitis,

2018
Elevated SGOT/SGPT ratio in alcoholic patients with acetaminophen hepatotoxicity.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:9

    Topics: Acetaminophen; Adult; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Chemical and Dr

1984
Problems in the necropsy diagnosis of alcoholic liver disease.
    The American journal of forensic medicine and pathology, 1984, Volume: 5, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; D

1984
Anti-LSP antibodies in acute liver disease.
    Gut, 1982, Volume: 23, Issue:7

    Topics: Acetaminophen; Acute Disease; Autoantibodies; Chemical and Drug Induced Liver Injury; Hepatitis, Alc

1982
[Acetaminophen and alcohol].
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Apr-04, Volume: 59, Issue:15

    Topics: Acetaminophen; Drug Interactions; Hepatitis, Alcoholic; Humans; Liver

1981
A jaundiced look at the management of hepatitis?
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1997, Volume: 87, Issue:7

    Topics: Acetaminophen; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Female; Halothane; Hepatiti

1997
[Massive increase in transaminases and thrombocytopenia. Acute drug-induced toxic hepatitis (probable culprit: paracetamol)].
    Praxis, 1997, Sep-17, Volume: 86, Issue:38

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Diagnosis, Differen

1997
[Protective action of seed oil of Hippophae rhamnoides L. (HR) against experimental liver injury in mice].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1992, Volume: 26, Issue:4

    Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Indu

1992
Recognizing acetaminophen hepatotoxicity in chronic alcoholics.
    Postgraduate medicine, 1992, Volume: 91, Issue:4

    Topics: Acetaminophen; Alcoholism; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Ove

1992
[Acute hepato-nephritis in an alcoholic following a therapeutic dose of paracetamol].
    Presse medicale (Paris, France : 1983), 1988, Jun-25, Volume: 17, Issue:25

    Topics: Acetaminophen; Acute Disease; Aged; Hepatitis, Alcoholic; Humans; Male; Middle Aged; Nephritis

1988