acetaminophen has been researched along with Alcoholic Cirrhosis in 14 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acetaminophen clearance and its partial clearance to its major metabolites has been determined before and after 5 days treatment with the anti-alcohol abuse agent disulfiram (200 mg daily)." | 3.68 | The influence of disulfiram on acetaminophen metabolism in man. ( Jørgensen, L; Poulsen, HE; Ranek, L, 1991) |
| " The entire spectrum of alcoholic liver disease, including alcoholic hepatitis, may be perfectly mimicked by severe obesity, diabetes, and perhexiline maleate toxicity." | 3.67 | Problems in the necropsy diagnosis of alcoholic liver disease. ( Pounder, DJ, 1984) |
| "Severe intoxication from excessive acetaminophen without suicidal intent occurred in three patients, all alcohol abusers, one with evidence of underlying cirrhosis." | 3.67 | Enhanced toxicity of acetaminophen in alcoholics: report of three cases. ( Gluskin, LE; Leist, MH; Payne, JA, 1985) |
| "Drug and substance abuse remains a major medical problem." | 2.49 | Liver abnormalities in drug and substance abusers. ( de Boer, B; MacQuillan, G; Pateria, P, 2013) |
| "Eighteen patients in hepatic coma grade III-IV were entered in the study and were divided into two groups in accordance with their renal function (serum creatinine above/below 180 mumol/l)." | 1.28 | Fractional excretion of beta-2-microglobulin in the urine of patients with normal or reduced renal function and hepatic coma. ( Dalhoff, K; Hansen, PB; Joffe, P; Olesen, B, 1991) |
| " The average biological half-life after oral administration of 1 g paracetamol was significantly prolonged in patients with hepatic cirrhosis compared to the controls (3." | 1.26 | Paracetamol (acetaminophen) clearance in patients with cirrhosis of the liver. ( Andreasen, PB; Hutters, L, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pateria, P | 1 |
| de Boer, B | 1 |
| MacQuillan, G | 1 |
| Vega, AB | 1 |
| Andreu, V | 1 |
| Perelló, A | 1 |
| Chahri, N | 1 |
| Córdova, H | 1 |
| Abad, A | 1 |
| Barenys, M | 1 |
| Villeneuve, JP | 1 |
| Raymond, G | 1 |
| Bruneau, J | 1 |
| Colpron, L | 1 |
| Pomier-Layrargues, G | 1 |
| Pounder, DJ | 1 |
| Langley, PG | 1 |
| Hughes, RD | 1 |
| Williams, R | 1 |
| Hastier, P | 1 |
| Paolini, O | 1 |
| Demarquay, JF | 1 |
| Caroli-Bosc, FX | 1 |
| Chichmanian, RM | 1 |
| Saint-Paul, MC | 1 |
| Delmont, J | 1 |
| Ueshima, Y | 1 |
| Tsutsumi, M | 1 |
| Takase, S | 1 |
| Matsuda, Y | 1 |
| Kawahara, H | 1 |
| Gould, TH | 1 |
| Cockings, JG | 1 |
| Buist, M | 1 |
| Schiff, ER | 1 |
| Andreasen, PB | 1 |
| Hutters, L | 1 |
| Hansen, PB | 1 |
| Dalhoff, K | 1 |
| Joffe, P | 1 |
| Olesen, B | 1 |
| Poulsen, HE | 1 |
| Ranek, L | 1 |
| Jørgensen, L | 1 |
| O'Dell, JR | 1 |
| Zetterman, RK | 1 |
| Burnett, DA | 1 |
| Leist, MH | 1 |
| Gluskin, LE | 1 |
| Payne, JA | 1 |
3 reviews available for acetaminophen and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Liver abnormalities in drug and substance abusers.
Topics: Acetaminophen; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrho | 2013 |
[Prolonged fever and jaundice in a patient with alcoholic liver disease].
Topics: Acetaminophen; Adult; Animals; Animals, Domestic; Antibodies, Bacterial; Antipyretics; Ascites; Chem | 2010 |
Update in hepatology.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Hepatitis; Hepatitis, Viral, Human; Humans; Liver Cirrhosis | 1999 |
11 other studies available for acetaminophen and Alcoholic Cirrhosis
| Article | Year |
|---|---|
[Pharmacokinetics and metabolism of acetaminophen in normal, alcoholic and cirrhotic subjects].
Topics: Acetaminophen; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Humans; Kinetics; Liver Ci | 1983 |
Problems in the necropsy diagnosis of alcoholic liver disease.
Topics: Acetaminophen; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; D | 1984 |
Platelet adhesiveness to glass beads in liver disease.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Chronic Disease; Glass; Hemoperfusion; Hepati | 1982 |
[Fulminant hepatitis induced by paracetamol at a therapeutic dose favoured by the ingestion of enzyme inducers in a patient with liver cirrhosis].
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Depressive D | 1995 |
Acetaminophen metabolism in patients with different cytochrome P-4502E1 genotypes.
Topics: Acetaminophen; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Ethanol; Genotype; Half-Life | 1996 |
Postoperative acute liver failure after therapeutic paracetamol administration.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Female; Humans; Liver Cirrhosis, Alcoholic; Liver Fa | 1997 |
Paracetamol (acetaminophen) clearance in patients with cirrhosis of the liver.
Topics: Acetaminophen; Adult; Aged; Antipyrine; Female; Half-Life; Humans; Kinetics; Liver Cirrhosis; Liver | 1979 |
Fractional excretion of beta-2-microglobulin in the urine of patients with normal or reduced renal function and hepatic coma.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Aged; beta 2-Microglobulin; Diagnosis, Differential; Fema | 1991 |
The influence of disulfiram on acetaminophen metabolism in man.
Topics: Acetaminophen; Adult; Aged; Alcoholism; Disulfiram; Drug Interactions; Female; Humans; Liver Cirrhos | 1991 |
Centrilobular hepatic fibrosis following acetaminophen-induced hepatic necrosis in an alcoholic.
Topics: Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Cirrhosis | 1986 |
Enhanced toxicity of acetaminophen in alcoholics: report of three cases.
Topics: Acetaminophen; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Drug Interactions; Ethanol | 1985 |