acetaminophen has been researched along with Alcohol Drinking in 92 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study explored the association between exposure to acetaminophen during pregnancy and pubertal development using data from 15,822 boys and girls in the longitudinal Puberty Cohort, nested within the Danish National Birth Cohort." | 7.91 | Acetaminophen (Paracetamol) Exposure During Pregnancy and Pubertal Development in Boys and Girls From a Nationwide Puberty Cohort. ( Brix, N; Ernst, A; Lauridsen, LLB; Liew, Z; Olsen, J; Olsen, LH; Parner, ET; Ramlau-Hansen, CH, 2019) |
| "In long-term alcohol users, the syndrome of hepatotoxicity from acetaminophen taken in therapeutic or modestly excessive doses is distinctive." | 7.70 | Alcohol-acetaminophen syndrome. Even moderate social drinkers are at risk. ( Cox, C; Draganov, P; Durrence, H; Reuben, A, 2000) |
| "This study explored the association between exposure to acetaminophen during pregnancy and pubertal development using data from 15,822 boys and girls in the longitudinal Puberty Cohort, nested within the Danish National Birth Cohort." | 3.91 | Acetaminophen (Paracetamol) Exposure During Pregnancy and Pubertal Development in Boys and Girls From a Nationwide Puberty Cohort. ( Brix, N; Ernst, A; Lauridsen, LLB; Liew, Z; Olsen, J; Olsen, LH; Parner, ET; Ramlau-Hansen, CH, 2019) |
| "To investigate the prevalence and type of health products used among pregnant women visiting a tertiary hospital in Belgium, as well as who advises these products, where women buy these products, which determinants are associated with medication and pregnancy vitamin intake, and preconception lifestyle changes such as folic acid intake and substance use." | 3.91 | Health products' and substance use among pregnant women visiting a tertiary hospital in Belgium: A cross-sectional study. ( Allegaert, K; Ceulemans, M; Foulon, V; Van Calsteren, K, 2019) |
| "To determine if subjects with chronic alcoholism are predisposed to acetaminophen-induced hepatotoxicity, and to determine the contributing factors." | 3.74 | Acetaminophen usage patterns and concentrations of glutathione and gamma-glutamyl transferase in alcoholic subjects. ( Anderson, DC; Seifert, CF, 2007) |
| "Warfarin is highly effective in preventing thromboembolism, but increases the risk of hemorrhage, particularly at an international normalized ratio (INR) greater than 4." | 3.70 | Acetaminophen and other risk factors for excessive warfarin anticoagulation. ( Heiman, H; Hylek, EM; Sheehan, MA; Singer, DE; Skates, SJ, 1998) |
| "In long-term alcohol users, the syndrome of hepatotoxicity from acetaminophen taken in therapeutic or modestly excessive doses is distinctive." | 3.70 | Alcohol-acetaminophen syndrome. Even moderate social drinkers are at risk. ( Cox, C; Draganov, P; Durrence, H; Reuben, A, 2000) |
| "We examined in a controlled study whether psychologic disturbances in men with peptic ulcer disease were related to other potential ulcer "risk factors" (serum pepsinogen concentrations, cigarette smoking, and intake of alcohol, aspirin, or coffee)." | 3.67 | Life events stress and psychosocial factors in men with peptic ulcer disease. II. Relationships with serum pepsinogen concentrations and behavioral risk factors. ( Feldman, M; Luther, J; Samloff, IM; Walker, P, 1988) |
| " However, the concentrations of APAP-CYS during therapeutic dosing, in cases of acetaminophen toxicity from repeated dosing and in cases of hepatic injury from non-acetaminophen hepatotoxins have not been well characterized." | 2.76 | Acetaminophen-cysteine adducts during therapeutic dosing and following overdose. ( Dart, RC; Green, JL; Heard, KJ; James, LP; Judge, BS; Rhyee, S; Zolot, L, 2011) |
| "Therapeutic dosing of paracetamol administered for 10 days appears to elevate serum ALT in moderate drinkers, but does not produce clinically evident liver injury." | 2.73 | A randomized trial to determine the change in alanine aminotransferase during 10 days of paracetamol (acetaminophen) administration in subjects who consume moderate amounts of alcohol. ( Bailey, JE; Bogdan, GM; Dart, RC; Green, JL; Heard, K, 2007) |
| " The failure to antagonize ethanol-induced subjective and physiologic effects by acetaminophen in humans may be due to species differences or inadequate dosage of the PGSI." | 2.67 | Acetaminophen fails to inhibit ethanol-induced subjective effects in human volunteers. ( George, FR; Henningfield, JE; Klein, SA; Pickworth, WB, 1992) |
| "Drug and substance abuse remains a major medical problem." | 2.49 | Liver abnormalities in drug and substance abusers. ( de Boer, B; MacQuillan, G; Pateria, P, 2013) |
| " Practitioners should caution patients to follow recommended dosage instructions and avoid taking multiple APAP-containing products." | 2.47 | The therapeutic applications of and risks associated with acetaminophen use: a review and update. ( Guggenheimer, J; Moore, PA, 2011) |
| " Studies performed in both experimental animals and humans indicate that chronic alcohol use leads to a short-term, two- to threefold increase in hepatic content of cytochrome P4502E1, the major isoform responsible for the generation of the toxic metabolite from paracetamol, although increased oxidative metabolism of paracetamol at recommended doses has not been demonstrated clinically." | 2.41 | Alcohol exposure and paracetamol-induced hepatotoxicity. ( Riordan, SM; Williams, R, 2002) |
| " Opioids should not be combined with alcohol, and meperidine must be avoided in the patient who has taken monoamine oxidase inhibitors in the previous 14 days." | 2.40 | Adverse drug interactions in dental practice: interactions associated with analgesics, Part III in a series. ( Haas, DA, 1999) |
| " In a double-blind, two-week, cross-over study, no clinical or laboratory evidence of adverse effects was found." | 2.36 | Hepatotoxicity following the therapeutic use of antipyretic analgesics. ( Benson, GD, 1983) |
| "Acetaminophen was involved in 81 (6." | 1.43 | Medication Overdoses at a Public Emergency Department in Santiago, Chile. ( Aguilera, P; Basaure, C; Garrido, M; Lara, B; Lessard, E; Mallon, WK; Saldias, F; Swadron, SP; Swanson, J, 2016) |
| " Adoption of these two recommendations may lead to the increased use of NSAIDs with the potential of increasing incidence of NSAIDs-related adverse reactions." | 1.36 | FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable? ( Day, RO; Graham, GG; Graudins, A; Mohamudally, A, 2010) |
| "Although used widely and recognized as a safe drug at therapeutic dose, acetaminophen has a narrow therapeutic margin." | 1.34 | [Acetaminophen: hepatotoxicity at therapeutic doses and risk factors]. ( Hadengue, A; Iten, A; Seirafi, M, 2007) |
| " The strongest predictor of severe hepatotoxicity was delayed or no N-acetyl cysteine treatment in patients consuming greater than 10 g of paracetamol or with toxic serum paracetamol levels." | 1.33 | Paracetamol overdose and hepatotoxicity at a regional Australian hospital: a 4-year experience. ( Ayonrinde, OA; Ayonrinde, OT; Hurley, JC; Phelps, GJ, 2005) |
| "Ibuprofen based drugs were the most frequently used OTC in both surveys (57% Roper, 33% NCL)." | 1.33 | Patterns of use and public perception of over-the-counter pain relievers: focus on nonsteroidal antiinflammatory drugs. ( Cryer, B; Triadafilopoulos, G; Wilcox, CM, 2005) |
| "Acetaminophen overdose is a frequent cause of acute liver failure." | 1.33 | Severe hepatotoxicity after therapeutic doses of acetaminophen. ( Cairon, E; Mian, P; Moling, O; Pristerá, R; Rimenti, G; Rizza, F, 2006) |
| " OTC NSAID users should be carefully advised as to recommended dose, and all patients should be reminded to stay within the dosing limits regardless which OTC analgesic is used." | 1.31 | The use and effect of analgesics in patients who regularly drink alcohol. ( Dart, RC, 2001) |
| "Dyspepsia is common in the general population, and despite a paucity of data, smoking, alcohol, and analgesics are believed to be important risk factors." | 1.29 | Smoking, alcohol, and analgesics in dyspepsia and among dyspepsia subgroups: lack of an association in a community. ( Melton, LJ; Schleck, CD; Talley, NJ; Zinsmeister, AR, 1994) |
| " In both patients starvation, due to abdominal pain, nausea and vomiting or diarrhoea, was probably contributing to the toxic effect of the drug." | 1.28 | Hepatotoxicity due to repeated intake of low doses of paracetamol. ( Broomé, U; Eriksson, LS; Kalin, M; Lindholm, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (15.22) | 18.7374 |
| 1990's | 26 (28.26) | 18.2507 |
| 2000's | 32 (34.78) | 29.6817 |
| 2010's | 15 (16.30) | 24.3611 |
| 2020's | 5 (5.43) | 2.80 |
| Authors | Studies |
|---|---|
| Qutob, HMH | 1 |
| Saad, RA | 1 |
| Bali, H | 1 |
| Osailan, A | 1 |
| Jaber, J | 1 |
| Alzahrani, E | 1 |
| Alyami, J | 1 |
| Elsayed, H | 1 |
| Alserihi, R | 1 |
| Shaikhomar, OA | 1 |
| Divya, KM | 1 |
| Savitha, DP | 1 |
| Krishna, GA | 1 |
| Dhanya, TM | 1 |
| Mohanan, PV | 1 |
| Shah, SF | 1 |
| Jafry, AT | 1 |
| Hussain, G | 1 |
| Kazim, AH | 1 |
| Ali, M | 1 |
| Rivani, E | 1 |
| Endraswari, PD | 1 |
| Widodo, ADW | 1 |
| Khalil, MR | 1 |
| Guldberg, R | 1 |
| Nørgård, BM | 1 |
| Uldbjerg, N | 1 |
| Wehberg, S | 1 |
| Fowobaje, KR | 1 |
| Mashood, LO | 1 |
| Ekholuenetale, M | 1 |
| Ibidoja, OJ | 1 |
| Romagnoli, A | 1 |
| D'Agostino, M | 1 |
| Pavoni, E | 1 |
| Ardiccioni, C | 1 |
| Motta, S | 1 |
| Crippa, P | 1 |
| Biagetti, G | 1 |
| Notarstefano, V | 1 |
| Rexha, J | 1 |
| Perta, N | 1 |
| Barocci, S | 1 |
| Costabile, BK | 1 |
| Colasurdo, G | 1 |
| Caucci, S | 1 |
| Mencarelli, D | 1 |
| Turchetti, C | 1 |
| Farina, M | 1 |
| Pierantoni, L | 1 |
| La Teana, A | 1 |
| Al Hadi, R | 1 |
| Cicconardi, F | 1 |
| Chinappi, M | 1 |
| Trucchi, E | 1 |
| Mancia, F | 1 |
| Menzo, S | 1 |
| Morozzo Della Rocca, B | 1 |
| D'Annessa, I | 1 |
| Di Marino, D | 1 |
| Choya, A | 1 |
| de Rivas, B | 1 |
| Gutiérrez-Ortiz, JI | 1 |
| López-Fonseca, R | 1 |
| Xu, S | 1 |
| Cheng, B | 1 |
| Huang, Z | 1 |
| Liu, T | 1 |
| Li, Y | 1 |
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| Xiong, J | 1 |
| Amirazodi, M | 1 |
| Daryanoosh, F | 1 |
| Mehrabi, A | 1 |
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| Salesi, M | 1 |
| Zarifkar, AH | 1 |
| Studeny, P | 1 |
| Netukova, M | 1 |
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| Klimesova, YM | 1 |
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| Kang, H | 1 |
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| Zhang, Q | 1 |
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| Moling, O | 1 |
| Cairon, E | 1 |
| Rimenti, G | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy and Safety of 36 Weeks Short-Term Optimization Treatment of Glucocorticosteroid in the Patients With Chronic Recurrent Drug-Induced Liver Injury[NCT03266146] | Phase 1/Phase 2 | 90 participants (Actual) | Interventional | 2017-09-02 | Completed | ||
| Pilot Study of a Smart Phone Assisted Problem Solving Therapy for Men Who Have Presented With Intentional Self-harm to Emergency Departments[NCT02718248] | 7 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| The BEACON Study: Protocol for Cluster RCT of a Service to Deliver Smartphone-Assisted Problem-Solving Therapy Compared to Usual Care in Men Who Present With Intentional Self-Harm to the ED in Ontario (Protocol A)[NCT03489382] | 0 participants (Actual) | Interventional | 2020-03-31 | Withdrawn (stopped due to Change in protocol design due to COVID-19 pandemic) | |||
| The BEACON Study: Protocol for a Pilot Randomized Controlled Trial of Smartphone-assisted Problem Solving Therapy in Men Who Present With Intentional Self-harm to Emergency Departments in Ontario[NCT03473535] | 100 participants (Anticipated) | Interventional | 2020-03-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Will be used to assess the feasibility of recruitment for a larger, multicentre cluster randomized controlled trial (RCT). To test feasibility in patients the investigators aim to recruit at least half of the men the study team ask to take part in the pilot study. To test feasibility in referring clinicians, the aim is that at least half of men who present with intentional self-harm to the psychiatric emergency service will be approached and complete the The Ottawa Hospital (TOH) form allowing contact details to be passed on to researchers. (NCT02718248)
Timeframe: Within 6 months of study launch
| Intervention | percentage of participants enrolled (Number) |
|---|---|
| CHESS Mobile Health Group | 46.6 |
Bodily Pain was measured using the Bodily Pain subscale of the Medical Outcomes Survey Short Form 12 (SF-12). The SF-12 is a 12-item self-report survey that assesses general health and well-being using a total of 8 subscales. The Bodily Pain Subscale is scored using a range of 0-100, with a higher score indicating lower levels of bodily pain. (NCT02718248)
Timeframe: Baseline, Week 5
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 71.43 | 82.14 |
"Measures change in the severity of depressive symptoms. Total scores on this scale range from 0 to 27, with higher scores indicating more severe depression symptoms. The scores on the Patient Health Questionnaire (PHQ-9) scale should be interpreted as follows:~0-4: Minimal Depression; 5-9: Mild Depression 10-14: Moderate Depression; 15-19: Moderately Severe Depression; 20 and Above: Severe Depression." (NCT02718248)
Timeframe: Baseline, Week 1, Week 2, Week 3, Week 4, Week 5
| Intervention | units on a scale (Mean) | ||||
|---|---|---|---|---|---|
| Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | |
| CHESS Mobile Health Group | 19.8 | 15.17 | 16.86 | 16.83 | 13.71 |
Emotional Role Limitations was measured using the Emotional Role Limitations subscale of the Medical Outcomes Survey Short Form 12 (SF-12). The SF-12 is a 12-item self-report survey that assesses general health and well-being using a total of 8 subscales. The Emotional Role Limitations Subscale is scored using a range of 0-100, with a higher score indicating fewer role limitations due to emotional health difficulties. (NCT02718248)
Timeframe: Baseline, Week 5
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 26.79 | 44.64 |
General Health was measured using the General Health subscale of the Medical Outcomes Survey Short Form 12 (SF-12). The SF-12 is a 12-item self-report survey that assesses general health and well-being using a total of 8 subscales. The General Health Subscale is scored using a range of 0-100, with a higher score indicating higher levels of general health. (NCT02718248)
Timeframe: Baseline, Week 5
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 42.14 | 48.57 |
Generic health-related quality of life index. The total scores on this measure range from 11111 to 33333, with lower values indicating higher levels of health-related quality of life. (NCT02718248)
Timeframe: Baseline and Week 5
| Intervention | units on a scale (Median) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 11223 | 11313 |
Mental Health Functioning was measured using the Mental Health subscale of the Medical Outcomes Survey Short Form 12 (SF-12). The SF-12 is a 12-item self-report survey that assesses general health and well-being using a total of 8 subscales. The Mental Health Functioning Subscale is scored using a range of 0-100, with a higher score indicating better mental health functioning. (NCT02718248)
Timeframe: Baseline, Week 5
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 17.86 | 30.36 |
The investigators will ask participants about the user comprehension, user practicality and the methods of data collection with regards to the CHESS Mobile Health smart phone application. The Participant Exit Questionnaire will also ask that users make comments or suggestions for future use and development of the application. This will test the acceptability of the intervention and the acceptability of using routine data sources as outcome measures. (NCT02718248)
Timeframe: within 4 months of study completion
| Intervention | percentage of participants who agreed (Number) | ||||||
|---|---|---|---|---|---|---|---|
| Application Easy to Install | Application is User Friendly | Application was easy to use | PST is a good fit for me | In PST we worked on what I wanted | Application was useful | I would use the application again | |
| CHESS Mobile Health Group | 100.0 | 85.7 | 71.4 | 71.4 | 85.7 | 28.6 | 42.9 |
Participants were asked to use the EuroQol 5 Dimensions Visual Analytic Scale to assess their overall health on a scale from 0 to 100, with 100 being the best possible health state. (NCT02718248)
Timeframe: Baseline, Week 5
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 47.57 | 60.29 |
Physical Functioning was measured using the Physical Functioning subscale of the Medical Outcomes Survey Short Form 12 (SF-12). The SF-12 is a 12-item self-report survey that assesses general health and well-being using a total of 8 subscales. The Physical Functioning Subscale is scored using a range of 0-100, with a higher score indicating better physical functioning. (NCT02718248)
Timeframe: Baseline and Week 5
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 82.14 | 92.86 |
Physical Role Limitations was measured using the Physical Role Limitations subscale of the Medical Outcomes Survey Short Form 12 (SF-12). The SF-12 is a 12-item self-report survey that assesses general health and well-being using a total of 8 subscales. The Physical Role Limitations Subscale is scored using a range of 0-100, with a higher score indicating fewer role limitations due to physical health difficulties. (NCT02718248)
Timeframe: Baseline, Week 5
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 75.0 | 83.93 |
Social Functioning was measured using the Social Functioning subscale of the Medical Outcomes Survey Short Form 12 (SF-12). The SF-12 is a 12-item self-report survey that assesses general health and well-being using a total of 8 subscales. The Social Functioning Subscale is scored using a range of 0-100, with a higher score indicating higher social functioning. (NCT02718248)
Timeframe: Baseline, Week 5
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 28.57 | 35.71 |
Vitality was measured using the Vitality subscale of the Medical Outcomes Survey Short Form 12 (SF-12). The SF-12 is a 12-item self-report survey that assesses general health and well-being using a total of 8 subscales. The Vitality subscale is scored using a range of 0-100, with a higher score indicating a higher degree of vitality. (NCT02718248)
Timeframe: Baseline, Week 5
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Week 5 | |
| CHESS Mobile Health Group | 25.00 | 46.43 |
15 reviews available for acetaminophen and Alcohol Drinking
| Article | Year |
|---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
[Acetaminophen and the liver: damage at therapeutic dose levels?].
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; D | 2011 |
Liver abnormalities in drug and substance abusers.
Topics: Acetaminophen; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrho | 2013 |
Drug Hepatotoxicity: Environmental Factors.
Topics: Acetaminophen; Alcohol Drinking; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Envi | 2017 |
Health maintenance issues in cirrhosis.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Comorbidity; Disease Progression; Health | 2009 |
The therapeutic applications of and risks associated with acetaminophen use: a review and update.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Drug Combinations; Drug Overdose; Humans; | 2011 |
Effect of therapeutic doses of acetaminophen (up to 4 g/day) on serum alanine aminotransferase levels in subjects consuming ethanol: systematic review and meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Alanine Transaminase; Alcohol Drinking; Analgesics, Non-Narcotic; Ethanol; Humans; Li | 2012 |
Acetaminophen misconceptions.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Drug Interactions; Humans; Liver; Phenoba | 2004 |
Hepatotoxicity following the therapeutic use of antipyretic analgesics.
Topics: Acetaminophen; Alcohol Drinking; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug | 1983 |
Acetaminophen-induced hepatotoxicity: predisposing factors and treatments.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Animals; Causality; Chemical and Drug Ind | 1997 |
[Clinical aspects of drug-alcohol interactions].
Topics: Acetaldehyde; Acetaminophen; Alcohol Deterrents; Alcohol Drinking; Animals; Carbon Tetrachloride; Ce | 1997 |
Ethanol interactions with other cytochrome P450 substrates including drugs, xenobiotics, and carcinogens.
Topics: Acetaminophen; Adult; Alcohol Drinking; Animals; Biotransformation; Carcinogens; Chemical and Drug I | 1998 |
Adverse drug interactions in dental practice: interactions associated with analgesics, Part III in a series.
Topics: Acetaminophen; Age Factors; Alcohol Drinking; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agen | 1999 |
Poisoning potpourri.
Topics: Acetaminophen; Age Factors; Alcohol Drinking; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac | 2001 |
Alcohol exposure and paracetamol-induced hepatotoxicity.
Topics: Acetaminophen; Alcohol Drinking; Alcoholism; Chemical and Drug Induced Liver Injury; Dose-Response R | 2002 |
6 trials available for acetaminophen and Alcohol Drinking
| Article | Year |
|---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
Acetaminophen-cysteine adducts during therapeutic dosing and following overdose.
Topics: Acetaminophen; Adolescent; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Chemical and Drug Induce | 2011 |
A randomized trial to determine the change in alanine aminotransferase during 10 days of paracetamol (acetaminophen) administration in subjects who consume moderate amounts of alcohol.
Topics: Acetaminophen; Adult; Alanine Transaminase; Alcohol Drinking; Analgesics, Non-Narcotic; Dose-Respons | 2007 |
The inhibition of gluconeogenesis following alcohol in humans.
Topics: Acetaminophen; Adult; Alcohol Drinking; Blood Glucose; Deuterium; Ethanol; Fasting; Galactose; Gas C | 1998 |
Acetaminophen use in patients who drink alcohol: current study evidence.
Topics: Acetaminophen; Adult; Alcohol Drinking; Analgesics, Non-Narcotic; Double-Blind Method; Drug Interact | 2001 |
Acetaminophen fails to inhibit ethanol-induced subjective effects in human volunteers.
Topics: Acetaminophen; Adult; Alcohol Drinking; Cyclooxygenase Inhibitors; Double-Blind Method; Ethanol; Hea | 1992 |
72 other studies available for acetaminophen and Alcohol Drinking
| Article | Year |
|---|---|
Potential biomarkers and metabolomics of acetaminophen-induced liver injury during alcohol consumption: A preclinical investigation on C57/BL6 mice.
Topics: Acetaminophen; Alcohol Drinking; Amino Acids; Animals; Biomarkers; Chemical and Drug Induced Liver I | 2023 |
Alcohol consumption is associated with the severity and outcome of acute liver injury/failure.
Topics: Acetaminophen; Aged; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Humans; Liver Failure | 2020 |
Acute Liver Injury With Therapeutic Doses of Acetaminophen: A Prospective Study.
Topics: Acetaminophen; Adult; Age Factors; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Drug Ind | 2021 |
The role of alcohol consumption on acetaminophen induced liver injury: Implications from a mathematical model.
Topics: Acetaminophen; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced L | 2021 |
Acetaminophen (Paracetamol) Exposure During Pregnancy and Pubertal Development in Boys and Girls From a Nationwide Puberty Cohort.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Child; Child, Preschool; Cigarette Smokin | 2019 |
Adolescent Nonmedical Use of Opioids and Alcohol Mixed with Energy Drinks.
Topics: Acetaminophen; Adolescent; Adolescent Behavior; Alcohol Drinking; Analgesics, Opioid; Drinking Behav | 2018 |
Health products' and substance use among pregnant women visiting a tertiary hospital in Belgium: A cross-sectional study.
Topics: Acetaminophen; Adolescent; Adult; Alcohol Drinking; Belgium; Counselors; Cross-Sectional Studies; Fe | 2019 |
Comparative analysis of acute toxic poisoning in 2003 and 2011: analysis of 3 academic hospitals.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Child; Child, Preschool | 2013 |
Paracetamol poisoning in adolescents in an Australian setting: not quite adults.
Topics: Acetaminophen; Adolescent; Adult; Alcohol Drinking; Analgesics, Non-Narcotic; Drug Overdose; Female; | 2015 |
Medication Overdoses at a Public Emergency Department in Santiago, Chile.
Topics: Acetaminophen; Adult; Alcohol Drinking; Ambulatory Care; Analgesics, Non-Narcotic; Antidepressive Ag | 2016 |
In this December issue.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Clinical Competence; Drug Overdose; Emerg | 2016 |
Use of over-the-counter analgesics is not associated with acute decompensation in patients with cirrhosis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Analgesics, Non-Narcotic; Anti-Infl | 2009 |
FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable?
Topics: Acetaminophen; Advisory Committees; Alcohol Drinking; Analgesics, Opioid; Anti-Inflammatory Agents, | 2010 |
Serum alanine aminotransferase elevation during 10 days of acetaminophen use in nondrinkers.
Topics: Acetaminophen; Adult; Alanine Transaminase; Alcohol Drinking; Female; Follow-Up Studies; Humans; Mal | 2010 |
Overdoing acetaminophen. Many overdoses are accidental, so the FDA may require new warnings on the popular pain reliever and lower the daily limit.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; D | 2009 |
The difficulty of risk assessment for hepatic injury associated with supra-therapeutic acetaminophen use.
Topics: Acetaminophen; Adolescent; Adult; Aged; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Dru | 2003 |
A 64 year old woman with knee pain: case outcome.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Decision Making; Drug Interactions; Femal | 2004 |
Prevalence of over-the-counter drug-related overdoses at Accident and Emergency departments in Northern Ireland--a retrospective evaluation.
Topics: Acetaminophen; Age Factors; Alcohol Drinking; Aspirin; Data Collection; Databases as Topic; Drug Com | 2005 |
Ethanol binging exacerbates sinusoidal endothelial and parenchymal injury elicited by acetaminophen.
Topics: Acetaminophen; Administration, Oral; Alcohol Drinking; Animals; Cells, Cultured; Disease Models, Ani | 2005 |
A new acetaminophen nomogram with a different purpose.
Topics: Acetaminophen; Acetylcysteine; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Drug Induced | 2005 |
A risk quantification instrument for acute acetaminophen overdose patients treated with N-acetylcysteine.
Topics: Acetaminophen; Acetylcysteine; Acute Disease; Adolescent; Adult; Alcohol Drinking; Analgesics, Non-N | 2005 |
Paracetamol overdose and hepatotoxicity at a regional Australian hospital: a 4-year experience.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Alcohol Drinking; Austr | 2005 |
Patterns of use and public perception of over-the-counter pain relievers: focus on nonsteroidal antiinflammatory drugs.
Topics: Acetaminophen; Adult; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Data Colle | 2005 |
How to handle a hangover. Drinking fluids may help with the morning-after misery from getting drunk.
Topics: Acetaminophen; Alcohol Drinking; Alcoholic Intoxication; Analgesics, Non-Narcotic; Contraindications | 2006 |
Survival after marked hyperlactaemia.
Topics: Acetaminophen; Adult; Alcohol Drinking; Analgesics, Non-Narcotic; Critical Care; Dextropropoxyphene; | 2006 |
Pain relievers and alcohol. A potentially risky combination.
Topics: Acetaminophen; Alcohol Drinking; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Interacti | 2006 |
Severe hepatotoxicity after therapeutic doses of acetaminophen.
Topics: Acetaminophen; Acetylcysteine; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Drug Induced | 2006 |
I take acetaminophen to help with my arthritis pain. Is it okay for me to drink wine while I'm taking this medication?
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Arthritis; Drug Interactions; Humans; Win | 2007 |
Self-harm in England: a tale of three cities. Multicentre study of self-harm.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Alcohol Drinking; Analgesics, Non-Narcotic; Anti | 2007 |
Self-harm in England: a tale of three cities. Multicentre study of self-harm.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Alcohol Drinking; Analgesics, Non-Narcotic; Anti | 2007 |
Self-harm in England: a tale of three cities. Multicentre study of self-harm.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Alcohol Drinking; Analgesics, Non-Narcotic; Anti | 2007 |
Self-harm in England: a tale of three cities. Multicentre study of self-harm.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Alcohol Drinking; Analgesics, Non-Narcotic; Anti | 2007 |
Self-harm in England: a tale of three cities. Multicentre study of self-harm.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Alcohol Drinking; Analgesics, Non-Narcotic; Anti | 2007 |
Self-harm in England: a tale of three cities. Multicentre study of self-harm.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Alcohol Drinking; Analgesics, Non-Narcotic; Anti | 2007 |
Self-harm in England: a tale of three cities. Multicentre study of self-harm.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Alcohol Drinking; Analgesics, Non-Narcotic; Anti | 2007 |
Self-harm in England: a tale of three cities. Multicentre study of self-harm.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Alcohol Drinking; Analgesics, Non-Narcotic; Anti | 2007 |
Self-harm in England: a tale of three cities. Multicentre study of self-harm.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Alcohol Drinking; Analgesics, Non-Narcotic; Anti | 2007 |
Acetaminophen usage patterns and concentrations of glutathione and gamma-glutamyl transferase in alcoholic subjects.
Topics: Acetaminophen; Adult; Alcohol Drinking; Alcoholism; Analgesics, Non-Narcotic; Biomarkers, Pharmacolo | 2007 |
Acute liver failure in two patients with regular alcohol consumption ingesting paracetamol at therapeutic dosage.
Topics: Acetaminophen; Aged; Aged, 80 and over; Alcohol Drinking; Analgesics, Non-Narcotic; Female; Humans; | 2007 |
[Acetaminophen: hepatotoxicity at therapeutic doses and risk factors].
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; D | 2007 |
Use of over-the-counter analgesics in patients with chronic liver disease: physicians' recommendations.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2008 |
[Paracetamol poisoning--clinical aspects and pharmacokinetics].
Topics: Acetaminophen; Acute Kidney Injury; Adult; Alcohol Drinking; Chemical and Drug Induced Liver Injury; | 1983 |
Acute iron intoxication with abruptly reduced levels of vitamin K-dependent coagulation factors.
Topics: Acetaminophen; Adolescent; Alcohol Drinking; Blood Coagulation Disorders; Female; Humans; Iron; Iron | 1982 |
The effect of mild alcohol consumption on the metabolism of acetaminophen in man.
Topics: Acetaminophen; Acetylcysteine; Alcohol Drinking; Ethanol; Humans; Liver; Time Factors | 1982 |
Environmental factors affecting paracetamol metabolism in London factory and office workers.
Topics: Acetaminophen; Adolescent; Adult; Aging; Alcohol Drinking; Asia; Diet; Environment; Female; Half-Lif | 1980 |
Ethanol induction of acetaminophen toxicity and metabolism.
Topics: Acetaminophen; Alcohol Drinking; Animals; Aspartate Aminotransferases; Cytochrome P-450 Enzyme Syste | 1980 |
The selling of acetaminophen.
Topics: Acetaminophen; Alcohol Drinking; Fasting; Humans; Liver; Liver Failure, Acute | 1995 |
Acetaminophen hepatotoxicity, fasting, and ethanol.
Topics: Acetaminophen; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Fasting; Humans; Nutrition | 1995 |
Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease.
Topics: Acetaminophen; Adult; Aged; Alcohol Drinking; Base Sequence; Chi-Square Distribution; Cytochrome P-4 | 1994 |
Alcohol and analgesics--mix extraordinaire.
Topics: Acetaminophen; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug | 1994 |
Association of acetaminophen hepatotoxicity with fasting and ethanol use.
Topics: Acetaminophen; Adolescent; Adult; Aged; Alcohol Drinking; Alcoholism; Chemical and Drug Induced Live | 1994 |
Smoking, alcohol, and analgesics in dyspepsia and among dyspepsia subgroups: lack of an association in a community.
Topics: Acetaminophen; Adult; Age Factors; Alcohol Drinking; Analgesics; Aspirin; Dyspepsia; Female; Humans; | 1994 |
The effects of hormone replacement therapy, lipoprotein cholesterol levels, and other factors on a clock drawing task in older women.
Topics: Acetaminophen; Aged; Aged, 80 and over; Alcohol Drinking; Cognition; Estrogen Replacement Therapy; E | 1996 |
Acetaminophen hepatotoxicity.
Topics: Acetaminophen; Adult; Alcohol Drinking; Fasting; Female; Humans; Liver Failure, Acute; Poisoning; Ri | 1996 |
Treating paracetamol overdose by charcoal haemoperfusion and long-hours high-flux dialysis.
Topics: Acetaminophen; Adolescent; Adult; Alcohol Drinking; Charcoal; Combined Modality Therapy; Drug Overdo | 1996 |
Rhabdomyolysis with acute renal failure and disseminated intravascular coagulation: association with acetaminophen and ethanol.
Topics: Acetaminophen; Acute Kidney Injury; Alcohol Drinking; Disseminated Intravascular Coagulation; Ethano | 1996 |
A jaundiced look at the management of hepatitis?
Topics: Acetaminophen; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Female; Halothane; Hepatiti | 1997 |
[Hepatotoxicity caused by paracetamol at therapeutic doses].
Topics: Acetaminophen; Acute Kidney Injury; Adult; Alcohol Drinking; Analgesics, Non-Narcotic; Humans; Liver | 1997 |
Acetaminophen and other risk factors for excessive warfarin anticoagulation.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Analgesics, Non-Narcotic; Anticoagu | 1998 |
I take Tylenol for arthritis. Should I avoid alcohol?
Topics: Acetaminophen; Alcohol Drinking; Drug Interactions; Humans | 1998 |
Acute liver failure induced by alcohol and paracetamol in an HCV-infected haemophiliac.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Alcohol Drinking; Analgesics, Non-Narcotic; Hemophilia B; | 1998 |
[Acetaminophen hepatotoxicity in an alcohol addicted student. Case report].
Topics: Acetaminophen; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Child; Humans; Male | 1999 |
Potential danger from too much acetaminophen in opiate agonist combination products.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Analgesics, Non-Narcoti | 1999 |
Alcohol-acetaminophen syndrome. Even moderate social drinkers are at risk.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Drug Interactions; Drug Overdose; Ethanol | 2000 |
Paracetamol hepatotoxicity and alcohol consumption in deliberate and accidental overdose.
Topics: Acetaminophen; Adolescent; Adult; Aged; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Dru | 2000 |
Pain medicine. The dangers of acetaminophen.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; D | 2001 |
New perspectives on acetaminophen and alcohol use.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Drug Interactions; Humans; Liver; Nonpres | 2001 |
The use and effect of analgesics in patients who regularly drink alcohol.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2001 |
Acute versus chronic alcohol consumption in acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Adult; Aging; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Drug Induced L | 2002 |
Letter: cysteamine treatment in paracetamol overdose.
Topics: Acetaminophen; Adult; Alcohol Drinking; Aspartate Aminotransferases; Chemical and Drug Induced Liver | 1975 |
Effects of indomethacin, aspirin, and acetaminophen on ethanol diuresis in rats.
Topics: Acetaminophen; Alcohol Drinking; Animals; Aspirin; Diuresis; Dose-Response Relationship, Drug; Femal | 1992 |
Hepatotoxicity due to repeated intake of low doses of paracetamol.
Topics: Acetaminophen; Adult; Alcohol Drinking; Diarrhea; Eating; Female; Hepatic Encephalopathy; Humans; Ma | 1992 |
Management of paracetamol poisoning complicated by enzyme induction due to alcohol or drugs.
Topics: Acetaminophen; Adolescent; Adult; Alcohol Drinking; Aspartate Aminotransferases; Humans; Liver; Male | 1990 |
Life events stress and psychosocial factors in men with peptic ulcer disease. II. Relationships with serum pepsinogen concentrations and behavioral risk factors.
Topics: Acetaminophen; Alcohol Drinking; Aspirin; Behavior; Coffee; Humans; Life Change Events; Male; Pepsin | 1988 |
Severe liver damage caused by therapeutic doses of acetaminophen.
Topics: Acetaminophen; Alanine Transaminase; Alcohol Drinking; Aspartate Aminotransferases; Chemical and Dru | 1987 |
Trends in analgesic self-poisoning in West-Fife, 1971-1985.
Topics: Acetaminophen; Adult; Alcohol Drinking; Analgesics; Dextropropoxyphene; Drug Combinations; Female; H | 1987 |
[Severe liver damage following therapeutic dose of paracetamol].
Topics: Acetaminophen; Adolescent; Adult; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Drug Syn | 1987 |
Environmental factors in aetiology of chronic gastric ulcer: a case control study of exposure variables before the first symptoms.
Topics: Acetaminophen; Alcohol Drinking; Analgesics; Anti-Inflammatory Agents; Aspirin; Chronic Disease; Fem | 1985 |
Paracetamol metabolism in African villagers.
Topics: Acetaminophen; Adult; Africa, Southern; Alcohol Drinking; Black People; Coffee; Diet; Female; Half-L | 1985 |
Effects of ethanol ingestion on the hepatotoxicity and metabolism of paracetamol in mice.
Topics: Acetaminophen; Alcohol Drinking; Alcoholism; Animals; Chemical and Drug Induced Liver Injury; Cytoch | 1985 |