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acetaminophen and Agranulocytosis

acetaminophen has been researched along with Agranulocytosis in 16 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"To determine whether metamizole is clinically safe compared to placebo and other analgesics."2.52Metamizole-associated adverse events: a systematic review and meta-analysis. ( Blozik, E; da Costa, BR; Fässler, M; Jüni, P; Kötter, T; Linde, K; Reichenbach, S; Scherer, M, 2015)
"Acetaminophen is an effective antipyretic and analgesic with few side effects that is toxic only in massive overdose."2.36Use of antipyretic analgesics in the pediatric patient. ( Gladtke, E, 1983)
"A diagnosis of drug-induced agranulocytosis was made."1.35[Angioimmunoblastic T-cell lymphoma complicated by recurrent drug-induced agranulocytosis]. ( Inoue, D; Kimura, T; Kurata, M; Maruoka, H; Matsushita, A; Mori, M; Nagai, K; Nagai, Y; Shimoji, S; Tabata, S; Takahashi, T; Yamashita, E, 2009)
"The risks of agranulocytosis and aplastic anemia in relation to analgesic drug use were evaluated in a population-based case-control study conducted in Europe and Israel."1.27Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study. ( , 1986)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199012 (75.00)18.7374
1990's1 (6.25)18.2507
2000's2 (12.50)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kötter, T1
da Costa, BR1
Fässler, M1
Blozik, E1
Linde, K1
Jüni, P1
Reichenbach, S1
Scherer, M1
Inoue, D1
Kimura, T1
Shimoji, S1
Mori, M1
Nagai, Y1
Tabata, S1
Kurata, M1
Matsushita, A1
Nagai, K1
Maruoka, H1
Yamashita, E1
Takahashi, T1
LLOYD, TW1
Avery, JK1
Gladtke, E1
Obel, AO1
Ell, C1
Domschke, S1
Domschke, W1
Jouet, JP1
Huart, JJ1
Bauters, F1
Goudemand, M1
Maraninchi, D1
Gastaut, JA1
Sebahoun, G1
Carcassonne, Y1
Ramos Fernández de Soria, R1
Martín Núñez, G1
Sánchez Gil, F1
Duhamel, G1
Najman, A1
Gorin, NC1
Rumack, BH1
Matthew, H1
Chichmanian, RM1
Taillan, B1
Fuzibet, JG1
Vinti, H1
Dujardin, P1
Benkirane-Agoumi, N1
Belkhadir, J1
Cherkaoui, O1
Dadi-el Fassi Fihri, O1
Bensouda, JD1
McIntyre, PA1
Laleli, YR1
Hodkinson, BA1
Wagner, HN1

Reviews

2 reviews available for acetaminophen and Agranulocytosis

ArticleYear
Metamizole-associated adverse events: a systematic review and meta-analysis.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Acetaminophen; Adult; Agranulocytosis; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non

2015
Use of antipyretic analgesics in the pediatric patient.
    The American journal of medicine, 1983, Nov-14, Volume: 75, Issue:5A

    Topics: Acetaminophen; Adolescent; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemic

1983

Other Studies

14 other studies available for acetaminophen and Agranulocytosis

ArticleYear
[Angioimmunoblastic T-cell lymphoma complicated by recurrent drug-induced agranulocytosis].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:2

    Topics: Acetaminophen; Aged; Agranulocytosis; Analgesics, Non-Narcotic; Cyclosporine; Humans; Immunoblastic

2009
Agranulocytosis associated with paracetamol.
    Lancet (London, England), 1961, Jan-14, Volume: 1, Issue:7168

    Topics: Acetaminophen; Acetanilides; Agranulocytosis; Humans

1961
Loss prevention case of the month. Monitoring remains critical.
    Tennessee medicine : journal of the Tennessee Medical Association, 2004, Volume: 97, Issue:1

    Topics: Acetaminophen; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Clini

2004
Presumed analgesic-induced agranulocytosis.
    East African medical journal, 1983, Volume: 60, Issue:4

    Topics: Acetaminophen; Agranulocytosis; Analgesics; Aspirin; Dipyrone; Humans; Phenacetin

1983
[Benefit-risk considerations in metamizole treatment. Rational recommendations for indications and contra-indications according to current knowledge].
    Fortschritte der Medizin, 1982, Apr-15, Volume: 100, Issue:14

    Topics: Acetaminophen; Agranulocytosis; Aminopyrine; Anaphylaxis; Aspirin; Dipyrone; Humans; Injections, Int

1982
[Paracetamol, an unrecognized cause of acute, drug-induced agranulocytosis].
    La Nouvelle presse medicale, 1980, Apr-26, Volume: 9, Issue:19

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Agranulocytosis; Female; Humans; Male; Middle Aged

1980
[Agranulocytosis caused by taking paracetamol? Value of the in vitro granulocyte progenitor test].
    La Nouvelle presse medicale, 1981, Jan-10, Volume: 10, Issue:1

    Topics: Acetaminophen; Aged; Agranulocytosis; Colony-Forming Units Assay; Female; Humans

1981
[Agranulocytosis induced by drugs. Rapid recovery with the early use of G-CSF].
    Sangre, 1994, Volume: 39, Issue:2

    Topics: Acetaminophen; Adult; Aged; Agranulocytosis; Dipyrone; Female; Granulocyte Colony-Stimulating Factor

1994
[Current aspects of agranulocytosis (15 cases)].
    Annales de medecine interne, 1977, Volume: 128, Issue:3

    Topics: Acetaminophen; Adult; Aged; Agranulocytosis; Ajmaline; Aminopyrine; Anti-Inflammatory Agents, Non-St

1977
Acetaminophen poisoning and toxicity.
    Pediatrics, 1975, Volume: 55, Issue:6

    Topics: Acetaminophen; Agranulocytosis; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Hypoglyc

1975
[Agranulocytosis caused by paracetamol: a case, with positive readministration].
    Annales de medecine interne, 1989, Volume: 140, Issue:4

    Topics: Acetaminophen; Aged; Agranulocytosis; Female; Humans

1989
[Apropos of a case of agranulocytosis caused by paracetamol].
    al-Maghrib al-tibbi. Maroc medical, 1986, Volume: 8, Issue:4

    Topics: Acetaminophen; Adult; Agranulocytosis; Female; Humans

1986
Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study.
    JAMA, 1986, Oct-03, Volume: 256, Issue:13

    Topics: Acetaminophen; Adult; Aged; Agranulocytosis; Aminopyrine; Analgesics; Anemia, Aplastic; Antipyrine;

1986
Evidence for anti-leukocyte antibodies as a mechanism for drug-induced agranulocytosis.
    Transactions of the Association of American Physicians, 1971, Volume: 84

    Topics: Acetaminophen; Adult; Aged; Agranulocytosis; Animals; Blood Transfusion; Carbon Dioxide; Carbon Radi

1971