acetaminophen has been researched along with Adjuvant Arthritis in 18 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effects of two non-steroidal anti-inflammatory analgesics (NSAIAs), acetylsalicylic acid (ASA) and acetaminophen, on sleep patterns in rats with adjuvant-induced arthritis." | 7.67 | Differential effects of acetylsalicylic acid and acetaminophen on sleep abnormalities in a rat chronic pain model. ( Helms, C; Landis, CA; Levine, JD; Robinson, CR, 1989) |
| "To describe an in vivo model in the rat in which change in weight distribution is used as a measure of disease progression and efficacy of acetaminophen and two nonsteroidal anti-inflammatory drugs (NSAIDs) in a model of monosodium iodoacetate (MIA)-induced osteoarthritis (OA)." | 3.72 | Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. ( Bove, SE; Brooker, RM; Calcaterra, SL; Guzman, RE; Huber, CM; Juneau, PL; Kilgore, KS; Schrier, DJ, 2003) |
| "We studied the effects of two non-steroidal anti-inflammatory analgesics (NSAIAs), acetylsalicylic acid (ASA) and acetaminophen, on sleep patterns in rats with adjuvant-induced arthritis." | 3.67 | Differential effects of acetylsalicylic acid and acetaminophen on sleep abnormalities in a rat chronic pain model. ( Helms, C; Landis, CA; Levine, JD; Robinson, CR, 1989) |
| "The data obtained from 5-day and long-term evaluations of acetaminophen (APAP) using the adjuvant arthritis rat model, demonstrated the anti-inflammatory and antiarthritic activities of APAP." | 3.66 | Anti-inflammatory and antiarthritic evaluation of acetaminophen and its potentiation of tolmetin. ( Gardocki, JF; Wong, S, 1983) |
| "The antinociceptive properties of suprofen [alpha-methyl-4-(thienylcarbonyl)benzene acetic acid] are described in a pathologically induced hyperalgesic model, the rat adjuvant arthritis flexion test." | 3.66 | Suprofen, a new peripheral analgesic. ( Capetola, RJ; Rosenthale, ME; Shriver, DA, 1980) |
| " Following dosing of CFA-injected rats with rofecoxib (Vioxx) or paracetamol, there was a significant decrease in the number of ipsilateral CGRP-IR small and medium DRG neurones in rofecoxib- but not paracetamol-treated rats." | 1.34 | Changes in dorsal root ganglion CGRP expression in a chronic inflammatory model of the rat knee joint: differential modulation by rofecoxib and paracetamol. ( Bountra, C; Chessell, IP; Day, NC; Staton, PC; Wilson, AW, 2007) |
| "Paracetamol is regarded as a relatively safe drug in the gastro-duodenal region of humans but recent epidemiological investigations have suggested that at high doses there may be an increased risk of ulcers and bleeding." | 1.33 | Paracetamol [acetaminophen]-induced gastrotoxicity: revealed by induced hyperacidity in combination with acute or chronic inflammation. ( Rainsford, KD; Whitehouse, MW, 2006) |
| " They were found fairly potent in rat tail flick and mouse phenylquinone writhing assays but the dose-response curves were rather shallow as compared to that of morphine." | 1.30 | Apparent antinociceptive and anti-inflammatory effects of GYKI 52466. ( Kedves, R; Máté, I; Székely, JI; Tarnawa, I; Török, K, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Kroos, S | 1 |
| Halima, M | 1 |
| Kroon, J | 1 |
| van der Woude, D | 1 |
| Meijer, OC | 1 |
| van de Wal, MD | 1 |
| Verhave, PS | 1 |
| Schaaf, MJ | 1 |
| Toes, RE | 1 |
| Kampstra, AS | 1 |
| Micheli, L | 1 |
| Bozdag, M | 1 |
| Akgul, O | 1 |
| Carta, F | 1 |
| Guccione, C | 1 |
| Bergonzi, MC | 1 |
| Bilia, AR | 1 |
| Cinci, L | 1 |
| Lucarini, E | 1 |
| Parisio, C | 1 |
| Supuran, CT | 1 |
| Ghelardini, C | 1 |
| Di Cesare Mannelli, L | 1 |
| Siemian, JN | 1 |
| Li, J | 1 |
| Zhang, Y | 1 |
| Li, JX | 1 |
| Kanashiro, A | 1 |
| Pessini, AC | 1 |
| Machado, RR | 1 |
| Malvar, Ddo C | 1 |
| Aguiar, FA | 1 |
| Soares, DM | 1 |
| do Vale, ML | 1 |
| de Souza, GE | 1 |
| Zupanets, IA | 1 |
| Tuliakov, VA | 1 |
| Shebeko, SK | 1 |
| Alfonso Romero-Sandoval, E | 1 |
| Del Soldato, P | 1 |
| Herrero, JF | 2 |
| Bove, SE | 1 |
| Calcaterra, SL | 1 |
| Brooker, RM | 1 |
| Huber, CM | 1 |
| Guzman, RE | 1 |
| Juneau, PL | 1 |
| Schrier, DJ | 1 |
| Kilgore, KS | 1 |
| Gaitán, G | 1 |
| Ahuir, FJ | 1 |
| Millecamps, M | 1 |
| Jourdan, D | 1 |
| Leger, S | 1 |
| Etienne, M | 1 |
| Eschalier, A | 1 |
| Ardid, D | 1 |
| Staton, PC | 1 |
| Wilson, AW | 1 |
| Bountra, C | 1 |
| Chessell, IP | 1 |
| Day, NC | 1 |
| Rainsford, KD | 1 |
| Whitehouse, MW | 1 |
| Wong, S | 1 |
| Gardocki, JF | 1 |
| Capetola, RJ | 1 |
| Shriver, DA | 1 |
| Rosenthale, ME | 1 |
| Abbadie, C | 1 |
| Besson, JM | 1 |
| Székely, JI | 1 |
| Kedves, R | 1 |
| Máté, I | 1 |
| Török, K | 1 |
| Tarnawa, I | 1 |
| Meunier, CJ | 1 |
| Verbeeck, RK | 1 |
| McQueen, DS | 1 |
| Iggo, A | 1 |
| Birrell, GJ | 1 |
| Grubb, BD | 1 |
| Landis, CA | 1 |
| Robinson, CR | 1 |
| Helms, C | 1 |
| Levine, JD | 1 |
18 other studies available for acetaminophen and Adjuvant Arthritis
| Article | Year |
|---|---|
Tramadol/paracetamol treatment attenuates the development of collagen antibody-induced arthritis and interferes with prednisolone treatment in mice.
Topics: Acetaminophen; Animals; Arthritis, Experimental; Collagen; Male; Mice; Prednisolone; Tramadol | 2023 |
Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, | 2019 |
Interactions between imidazoline I2 receptor ligands and acetaminophen in adult male rats: antinociception and schedule-controlled responding.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arthritis, Experimental; Benzofurans; Conditioning | 2016 |
Characterization and pharmacological evaluation of febrile response on zymosan-induced arthritis in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arthritis, Experimental; Body Temperature; Celecox | 2009 |
[Effect of glucosamine hydrochloride in combination with paracetamol on chondrocyte apoptosis under conditions of systemic steroidal arthritis development in rats].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Arthritis, Experimental; Cartilage, Art | 2012 |
The effects of sham and full spinalization on the antinociceptive effects of NCX-701 (nitroparacetamol) in monoarthritic rats.
Topics: Acetaminophen; Analgesics; Animals; Arthritis, Experimental; Chloralose; Male; Pain Measurement; Phy | 2003 |
Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis | 2003 |
Enhancement of fentanyl antinociception by subeffective doses of nitroparacetamol (NCX-701) in acute nociception and in carrageenan-induced monoarthritis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non- | 2005 |
Circadian pattern of spontaneous behavior in monarthritic rats: a novel global approach to evaluation of chronic pain and treatment effectiveness.
Topics: Acetaminophen; Activity Cycles; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthri | 2005 |
Changes in dorsal root ganglion CGRP expression in a chronic inflammatory model of the rat knee joint: differential modulation by rofecoxib and paracetamol.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arthritis, Experimental; Calcitonin Gene-Related P | 2007 |
Paracetamol [acetaminophen]-induced gastrotoxicity: revealed by induced hyperacidity in combination with acute or chronic inflammation.
Topics: Acetaminophen; Acute Disease; Administration, Oral; Analgesics, Non-Narcotic; Animals; Arthritis, Ex | 2006 |
Anti-inflammatory and antiarthritic evaluation of acetaminophen and its potentiation of tolmetin.
Topics: Acetaminophen; Animals; Arthritis; Arthritis, Experimental; Drug Evaluation, Preclinical; Drug Thera | 1983 |
Suprofen, a new peripheral analgesic.
Topics: Acetaminophen; Analgesics; Animals; Arachidonic Acids; Arthritis, Experimental; Biological Assay; Ca | 1980 |
Chronic treatments with aspirin or acetaminophen reduce both the development of polyarthritis and Fos-like immunoreactivity in rat lumbar spinal cord.
Topics: Acetaminophen; Animals; Arthritis, Experimental; Aspirin; Avidin; Biotin; Freund's Adjuvant; Immunoh | 1994 |
Apparent antinociceptive and anti-inflammatory effects of GYKI 52466.
Topics: Acetaminophen; Analgesics; Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents; Arthritis, Experi | 1997 |
Glucuronidation of R- and S-ketoprofen, acetaminophen, and diflunisal by liver microsomes of adjuvant-induced arthritic rats.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chromatogr | 1999 |
Effects of paracetamol and aspirin on neural activity of joint mechanonociceptors in adjuvant arthritis.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; E | 1991 |
Differential effects of acetylsalicylic acid and acetaminophen on sleep abnormalities in a rat chronic pain model.
Topics: Acetaminophen; Animals; Arthritis; Arthritis, Experimental; Aspirin; Male; Pain; Rats; Rats, Inbred | 1989 |