acetaminophen has been researched along with Addiction, Opioid in 79 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We describe considerations of concurrent buprenorphine/naloxone therapy during episodes of severe acute pain." | 7.79 | Acute pain control challenges with buprenorphine/naloxone therapy in a patient with compartment syndrome secondary to McArdle's disease: a case report and review. ( Chang-Chien, GC; Chu, SK; Joseph, P; McCormick, Z, 2013) |
| "Buprenorphine formulations (including buprenorphine/naloxone) are effective treatments of pain and opioid use disorder (OUD)." | 5.22 | Perioperative Buprenorphine Management: A Multidisciplinary Approach. ( Abelleira, A; Acampora, G; Becker, WC; Falker, CG; Hickey, T; Nazario, M; Weimer, MB, 2022) |
| "The aim of this study was to determine whether the administration of liposomal bupivacaine decreased opioid use and delirium in patients sustaining a hip fracture." | 4.31 | Liposomal Bupivacaine Decreases Intravenous Opioid Use in Patients with Hip Fracture: A Modification to a Novel Pain Protocol. ( Donegan, D; Fryhofer, GW; Looby, S; Mehta, S; Stein, MK; Stevenson, KL, 2023) |
| " The protocol utilized oral celecoxib and scheduled oral acetaminophen for pain control, with opioids used only as needed for breakthrough pain." | 3.91 | Multimodal Postoperative Pain Control Is Effective and Reduces Opioid Use After Laparoscopic Roux-en-Y Gastric Bypass. ( Dove, J; Fluck, M; Gabrielsen, JD; Gionfriddo, MR; Horsley, RD; McField, DAP; Medico, C; Parker, DM; Petrick, AT; Vogels, ED, 2019) |
| " We describe considerations of concurrent buprenorphine/naloxone therapy during episodes of severe acute pain." | 3.79 | Acute pain control challenges with buprenorphine/naloxone therapy in a patient with compartment syndrome secondary to McArdle's disease: a case report and review. ( Chang-Chien, GC; Chu, SK; Joseph, P; McCormick, Z, 2013) |
| "The responses pertaining to opioid agreements, urine drug testing, acetaminophen, and treatment for neuropathic pain are reassuring in that they prevent misuse and abuse of opioids, prevent acetaminophen-induced hepatotoxicity, and reflect evidence-based treatments." | 3.79 | Prescription patterns of pain medicine physicians. ( Avram, MJ; Benzon, HA; Benzon, HT; Cox, P; Dean, K; Katz, JA; Kendall, MC; Malik, K, 2013) |
| " This open-label study (NCT03974932) evaluated the efficacy and safety of HTX-011 combined with an MMA regimen in patients undergoing TKA under spinal anesthesia." | 3.30 | HTX-011 in Combination with Multimodal Analgesic Regimen Minimized Severe Pain and Opioid Use after Total Knee Arthroplasty in an Open-Label Study. ( Berkowitz, R; Hacker, S; Hu, J; Lee, GC; Rechter, A, 2023) |
| " Median Tmax of hydrocodone following benzhydrocodone API was delayed by more than one hour compared with HB." | 2.87 | Pharmacokinetics and Abuse Potential of Benzhydrocodone, a Novel Prodrug of Hydrocodone, After Intranasal Administration in Recreational Drug Users. ( Barrett, AC; Dickerson, D; Guenther, SM; Mickle, TC; Roupe, KA; Webster, LR; Zhou, J, 2018) |
| "The increasing rate of opioid abuse warrants standardization of postoperative pain management." | 2.87 | Opioid Use following Outpatient Breast Surgery: Are Physicians Part of the Problem? ( Broecker, JS; Hart, AM; Kao, L; Losken, A, 2018) |
| " This study evaluated the pharmacokinetics of three hydrocodone ER tablet prototypes with varying levels of polymer coating to identify the prototype expected to have the greatest abuse deterrence potential based on pharmacokinetic characteristics that maintain systemic exposure to hydrocodone comparable to that of a commercially available hydrocodone immediate-release (IR) product." | 2.80 | Pharmacokinetics of hydrocodone extended-release tablets formulated with different levels of coating to achieve abuse deterrence compared with a hydrocodone immediate-release/acetaminophen tablet in healthy subjects. ( Bond, M; Darwish, M; Robertson, P; Tracewell, W; Yang, R, 2015) |
| "The rate of pregnant women with an opioid use disorder has risen drastically in the past 20 years, paralleling that in the general population." | 2.66 | Opioid Use and Misuse in Pregnancy. ( Landau, R; Shatil, B, 2020) |
| "Pain is the most prominent symptom and clinical finding in osteoarthritis (OA)." | 2.41 | Treatment of chronic pain in osteoarthritis: do opioids have a clinical role? ( Lipman, AG, 2001) |
| "· ERAS protocols improve postoperative pain control and lower postoperative opioid use." | 1.72 | Enhanced Recovery after Surgery Protocol to Improve Racial and Ethnic Disparities in Postcesarean Pain Management. ( Berghella, V; Cao, CD; Dayaratna, S; Felder, L; Konys, C; Mercier, R; Weerasooriya, N, 2022) |
| "Complex and invasive postoperative pain regimens for microtia reconstruction with costal cartilage are often utilized." | 1.72 | Pain management after microtia repair with costal cartilage: De-escalation and opioid use reduction. ( Epperson, MV; Kim, HM; Kim, JC; VanHorn, A; Zopf, D, 2022) |
| "Legg-Calvé-Perthes disease (LCPD) and slipped capital femoral epiphysis (SCFE) can result in painful deformation of the hip joint with impaired range of motion and early development of secondary osteoarthritis." | 1.72 | Pediatric Hip Disease Increases the Risk for Opioid Use in Adulthood: Long-term Burden of Pain and Depression. ( Hailer, YD; Wadström, MG, 2022) |
| "Acetaminophen first was associated with reduced opioid use on the day prior to and on the day of discharge (3." | 1.72 | Underutilization of Acetaminophen in Older Adult Trauma Patients. ( Agarwal, S; Antonescu, I; Bartz, RR; Cox, CE; Fuller, M; Haines, KL; Krishnamoorthy, V; Ohnuma, T; Raghunathan, K; Vaughan, JG, 2022) |
| "Women with opioid use disorder or postoperative intubation were excluded." | 1.72 | A standardized post-cesarean analgesia regimen reduces postpartum opioid use. ( Antony, KM; Broman, AT; Gnadt, SE; Meyer, MF; Sharma, S, 2022) |
| " Adverse nasal effects were more frequent for intranasal benzhydrocodone/APAP vs intranasal HB/APAP." | 1.48 | Relative Bioavailability, Intranasal Abuse Potential, and Safety of Benzhydrocodone/Acetaminophen Compared with Hydrocodone Bitartrate/Acetaminophen in Recreational Drug Abusers. ( Barrett, AC; Guenther, SM; Lam, V; Mickle, TC; Roupe, KA; Zhou, J, 2018) |
| " In this situation, newborns might be exposed to toxic levels of morphine when breastfeeding." | 1.34 | Safety of codeine during breastfeeding: fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine. ( Aleksa, K; Cairns, J; Chitayat, D; Gaedigk, A; Karaskov, T; Koren, G; Leeder, JS; Madadi, P; Teitelbaum, R, 2007) |
| "Dextropropoxyphene has been increasingly prescribed as an analgesic in the UK, chiefly in the form of Distalgesic (dextropropoxyphene hydrochloride 32." | 1.27 | Dextropropoxyphene deaths: coroner's report. ( Whittington, RM, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.27) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (10.13) | 29.6817 |
| 2010's | 46 (58.23) | 24.3611 |
| 2020's | 24 (30.38) | 2.80 |
| Authors | Studies |
|---|---|
| Marwaha, S | 1 |
| Hickey, T | 1 |
| Abelleira, A | 1 |
| Acampora, G | 1 |
| Becker, WC | 1 |
| Falker, CG | 1 |
| Nazario, M | 1 |
| Weimer, MB | 1 |
| Patel, AK | 1 |
| Gai, J | 1 |
| Trujillo-Rivera, E | 1 |
| Faruqe, F | 1 |
| Kim, D | 1 |
| Bost, JE | 1 |
| Pollack, MM | 1 |
| Shafeeq, H | 1 |
| DiGiacomo, JC | 1 |
| Sookraj, KA | 1 |
| Gerber, N | 1 |
| Bahr, A | 1 |
| Talreja, ON | 1 |
| Munnangi, S | 1 |
| Cardozo-Stolberg, S | 1 |
| Angus, LDG | 1 |
| Felder, L | 1 |
| Cao, CD | 1 |
| Konys, C | 1 |
| Weerasooriya, N | 1 |
| Mercier, R | 1 |
| Berghella, V | 1 |
| Dayaratna, S | 1 |
| Vavolizza, RD | 1 |
| Grabski, DF | 1 |
| Roecker, Z | 1 |
| Levin, D | 1 |
| Swanson, JR | 1 |
| McGahren, ED | 1 |
| Gander, JW | 1 |
| Lee, GC | 1 |
| Berkowitz, R | 1 |
| Hacker, S | 1 |
| Hu, J | 1 |
| Rechter, A | 1 |
| Dahl, ME | 1 |
| McDonald, KC | 1 |
| Brown, O | 1 |
| Halder, G | 1 |
| Crouss, T | 1 |
| Pan, C | 1 |
| Eckhardt, S | 1 |
| Hoover, M | 1 |
| Dancz, CE | 1 |
| Sherrer, R | 1 |
| Su, R | 1 |
| O'Kelly, F | 1 |
| Borza, T | 1 |
| Byrne, A | 1 |
| Finup, J | 1 |
| Farhat, W | 1 |
| Epperson, MV | 1 |
| VanHorn, A | 1 |
| Kim, HM | 1 |
| Kim, JC | 1 |
| Zopf, D | 1 |
| Wadström, MG | 1 |
| Hailer, YD | 1 |
| Falise, AM | 2 |
| Sharma, V | 2 |
| Hoeflich, CC | 2 |
| Lopez-Quintero, C | 2 |
| Striley, CW | 2 |
| Stevenson, KL | 1 |
| Stein, MK | 1 |
| Fryhofer, GW | 1 |
| Looby, S | 1 |
| Donegan, D | 1 |
| Mehta, S | 1 |
| Dersch-Mills, D | 1 |
| Howlett, A | 1 |
| Lind, J | 1 |
| Marchuk, A | 1 |
| Mohammad, K | 1 |
| de Dios, C | 1 |
| Suchting, R | 1 |
| Green, C | 1 |
| Klugh, JM | 1 |
| Harvin, JA | 1 |
| Webber, HE | 1 |
| Schmitz, JM | 1 |
| Lane, SD | 1 |
| Yoon, JH | 1 |
| Heads, A | 1 |
| Motley, K | 1 |
| Stotts, A | 1 |
| Tong, K | 1 |
| Nolan, W | 1 |
| O'Sullivan, DM | 1 |
| Sheiner, P | 1 |
| Kutzler, HL | 1 |
| Nogrady, B | 1 |
| Derefinko, KJ | 1 |
| Salgado García, FI | 1 |
| Johnson, KC | 1 |
| Hand, S | 1 |
| Murphy, JG | 1 |
| McDevitt-Murphy, M | 1 |
| Suda, KJ | 1 |
| Andrasik, F | 1 |
| Bursac, Z | 1 |
| Chiu, CY | 1 |
| Talley, K | 1 |
| Brooks, JH | 1 |
| Kimergård, A | 1 |
| Parkin, S | 1 |
| Jennings, S | 1 |
| Brobbin, E | 1 |
| Deluca, P | 1 |
| Shatil, B | 1 |
| Landau, R | 1 |
| Stanley, LR | 1 |
| Crabtree, MA | 1 |
| Swaim, RC | 1 |
| Birchall, CL | 1 |
| Maines, JL | 1 |
| Kunselman, AR | 1 |
| Stetter, CM | 1 |
| Pauli, JM | 1 |
| Haines, KL | 1 |
| Fuller, M | 1 |
| Antonescu, I | 1 |
| Vaughan, JG | 1 |
| Raghunathan, K | 1 |
| Cox, CE | 1 |
| Bartz, RR | 1 |
| Ohnuma, T | 1 |
| Agarwal, S | 1 |
| Krishnamoorthy, V | 1 |
| Mokhtari, NB | 1 |
| Saeed, H | 1 |
| Kawakita, T | 1 |
| Huang, JC | 1 |
| Iqbal, SN | 1 |
| Meyer, MF | 1 |
| Broman, AT | 1 |
| Gnadt, SE | 1 |
| Sharma, S | 1 |
| Antony, KM | 1 |
| Hernandez, NM | 1 |
| Parry, JA | 1 |
| Taunton, MJ | 1 |
| Mazer-Amirshahi, M | 2 |
| Motov, S | 1 |
| Nelson, L | 1 |
| Prabhu, M | 1 |
| Bortoletto, P | 1 |
| Bateman, BT | 1 |
| Guenther, SM | 2 |
| Mickle, TC | 2 |
| Barrett, AC | 2 |
| Roupe, KA | 2 |
| Zhou, J | 2 |
| Lam, V | 1 |
| Oltman, J | 1 |
| Militsakh, O | 1 |
| D'Agostino, M | 1 |
| Kauffman, B | 1 |
| Lindau, R | 1 |
| Coughlin, A | 1 |
| Lydiatt, W | 1 |
| Lydiatt, D | 1 |
| Smith, R | 1 |
| Panwar, A | 1 |
| Dickerson, D | 1 |
| Webster, LR | 1 |
| Lyapustina, T | 1 |
| Castillo, R | 1 |
| Omaki, E | 1 |
| Shields, W | 1 |
| McDonald, E | 1 |
| Rothman, R | 1 |
| Gielen, A | 1 |
| Fredheim, OMS | 1 |
| Visconti, A | 1 |
| Kaye, AD | 1 |
| Cornett, EM | 1 |
| Hart, B | 1 |
| Patil, S | 1 |
| Pham, A | 1 |
| Spalitta, M | 1 |
| Mancuso, KF | 1 |
| Zaretsky, M | 1 |
| Wood, C | 1 |
| Nivens, T | 1 |
| McLaughlin, G | 1 |
| Zuk, J | 1 |
| Pan, Z | 1 |
| Chow, F | 1 |
| Hart, AM | 1 |
| Broecker, JS | 1 |
| Kao, L | 1 |
| Losken, A | 1 |
| Raneses, E | 1 |
| Secrist, ES | 1 |
| Freedman, KB | 1 |
| Sohn, DH | 1 |
| Fleeter, TB | 1 |
| Aland, CM | 1 |
| Kwan, TM | 1 |
| Sullivan, M | 1 |
| Horsley, RD | 1 |
| Vogels, ED | 1 |
| McField, DAP | 1 |
| Parker, DM | 1 |
| Medico, C | 1 |
| Dove, J | 1 |
| Fluck, M | 1 |
| Gabrielsen, JD | 1 |
| Gionfriddo, MR | 1 |
| Petrick, AT | 1 |
| Housman, JM | 1 |
| Williams, RD | 1 |
| Gross, JL | 1 |
| Perate, AR | 1 |
| Elkassabany, NM | 1 |
| Walley, AY | 1 |
| Wakeman, SE | 1 |
| Eng, G | 1 |
| Harnett, JT | 1 |
| Dines, AM | 1 |
| Wood, DM | 1 |
| Archer, JRH | 1 |
| Dargan, PI | 1 |
| Razdan, R | 1 |
| Stevens, L | 1 |
| Ritchie, M | 1 |
| Kennedy, T | 1 |
| Carr, MM | 1 |
| McCormick, Z | 1 |
| Chu, SK | 1 |
| Chang-Chien, GC | 1 |
| Joseph, P | 1 |
| Reid, N | 1 |
| Clancy, C | 1 |
| James, L | 1 |
| van den Anker, J | 1 |
| Meyer, CR | 1 |
| Gupta, D | 1 |
| Christensen, C | 1 |
| Soskin, V | 1 |
| McNaughton, EC | 1 |
| Coplan, PM | 1 |
| Black, RA | 1 |
| Weber, SE | 1 |
| Chilcoat, HD | 1 |
| Butler, SF | 1 |
| McCarthy, DM | 1 |
| Cameron, KA | 1 |
| King, JP | 1 |
| Mullen, RJ | 1 |
| Bailey, SC | 1 |
| Jacobson, KL | 1 |
| Di Francesco, L | 1 |
| Davis, TC | 1 |
| Parker, RM | 1 |
| Wolf, MS | 1 |
| Vosler, PS | 1 |
| Ferguson, BJ | 1 |
| Contreras, JI | 1 |
| Wang, EW | 1 |
| Schaitkin, BM | 1 |
| Lee, S | 1 |
| Darwish, M | 1 |
| Bond, M | 1 |
| Tracewell, W | 1 |
| Robertson, P | 1 |
| Yang, R | 1 |
| Hard, B | 1 |
| Pergolizzi, JV | 2 |
| Taylor, R | 1 |
| Raffa, RB | 1 |
| Eisenhauer, TD | 1 |
| Matchett, M | 1 |
| Heasley, R | 1 |
| Morton, T | 1 |
| Devarakonda, K | 1 |
| Giuliani, M | 1 |
| Young, JL | 1 |
| Barrett, T | 1 |
| Chan, B | 1 |
| Lopez, A | 1 |
| Sarkar, U | 1 |
| Cairns, R | 1 |
| Brown, JA | 1 |
| Buckley, NA | 1 |
| Palamar, JJ | 1 |
| Shearston, JA | 1 |
| Cleland, CM | 1 |
| Rigby, MH | 1 |
| Parnes, LS | 1 |
| Fredheim, OM | 1 |
| Nøstdahl, T | 1 |
| Nordstrand, B | 1 |
| Høivik, T | 1 |
| Rygnestad, T | 1 |
| Borchgrevink, PC | 1 |
| Green, TJ | 1 |
| Bijlsma, JJ | 1 |
| Sweet, DD | 1 |
| Williams, BS | 1 |
| Wong, D | 1 |
| Amin, S | 1 |
| Hersh, EV | 1 |
| Kane, WT | 1 |
| O'Neil, MG | 1 |
| Kenna, GA | 1 |
| Katz, NP | 1 |
| Golubic, S | 1 |
| Moore, PA | 1 |
| Casas, M | 1 |
| Gómez, C | 1 |
| Sainz, S | 1 |
| Soriano, G | 1 |
| Balanzó, J | 1 |
| Alexander, D | 1 |
| Alexander, K | 1 |
| Valentino, J | 1 |
| Doe, J | 1 |
| Benzon, HT | 1 |
| Kendall, MC | 1 |
| Katz, JA | 1 |
| Benzon, HA | 1 |
| Malik, K | 1 |
| Cox, P | 1 |
| Dean, K | 1 |
| Avram, MJ | 1 |
| Cicero, TJ | 2 |
| Inciardi, JA | 2 |
| Adams, EH | 2 |
| Geller, A | 2 |
| Senay, EC | 2 |
| Woody, GE | 2 |
| Muñoz, A | 2 |
| Dickson, DJ | 1 |
| Madadi, P | 1 |
| Koren, G | 1 |
| Cairns, J | 1 |
| Chitayat, D | 1 |
| Gaedigk, A | 1 |
| Leeder, JS | 1 |
| Teitelbaum, R | 1 |
| Karaskov, T | 1 |
| Aleksa, K | 1 |
| Birchenough, SA | 1 |
| Borowitz, K | 1 |
| Lin, KY | 1 |
| Whittington, RM | 1 |
| Lipman, AG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery[NCT03959969] | 48 participants (Actual) | Interventional | 2019-07-17 | Completed | |||
| Optimization of Opioid Discharge Prescriptions Following Thyroid and Parathyroid Surgeries[NCT04955444] | 240 participants (Actual) | Interventional | 2021-06-14 | Completed | |||
| Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: a Prospective Study.[NCT05287217] | 60 participants (Anticipated) | Interventional | 2022-07-29 | Not yet recruiting | |||
| Use of Single Dose Pre-Operative Pregabalin for Post-Operative Analgesia in Bilateral Head and Neck Cancer Surgery: A Randomized, Double-Blinded, Placebo-Controlled Trial[NCT03714867] | Phase 4 | 0 participants (Actual) | Interventional | 2019-03-22 | Withdrawn (stopped due to Inability to recruit patients) | ||
| A Prospective, Randomized Trial of the Effect of Standard of Care Reduced Dose Versus Full Dose Buprenorphine/Naloxone in the Perioperative Period on Pain Control and Post Operative Opioid Use Disorder Symptoms[NCT03266445] | Phase 4 | 76 participants (Anticipated) | Interventional | 2018-10-05 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Proportion of patients who receive new opioid discharge prescriptions at discharge following a thyroidectomy or parathyroidectomy procedure. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 128 |
| Post-implementation Group | 28 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients who receive new opioid prescriptions from the surgeon's office within 7 days of surgery including discharge prescriptions. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 0 |
| Post-implementation Group | 0 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding the recommended dose of 112.5 oral MMEs (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 52 |
| Post-implementation Group | 8 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding 5 days of therapy (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 27 |
| Post-implementation Group | 5 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid prescriptions exceeding 50 oral MMEs/day when new, postoperative discharge prescriptions are added to existing opioid therapy (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 9 |
| Post-implementation Group | 0 |
12 reviews available for acetaminophen and Addiction, Opioid
| Article | Year |
|---|---|
Perioperative Buprenorphine Management: A Multidisciplinary Approach.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2022 |
Opioid Use and Misuse in Pregnancy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory A | 2020 |
Perioperative pain management strategies among women having reproductive surgeries.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Evidence-Based Med | 2017 |
[Pain management for cancer patients in drug-assisted rehabilitation].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2018 |
Novel Pharmacological Nonopioid Therapies in Chronic Pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Chronic Pain; Humans; Opioid-R | 2018 |
The Use of Intravenous Ibuprofen and Intravenous Acetaminophen in Surgical Patients and the Effect on Opioid Reduction.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Female; Humans; Ibuprofe | 2017 |
Pain Management in Trauma in the Age of the Opioid Crisis.
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Gabapentin; Humans | 2019 |
Cold water extraction of codeine/paracetamol combination products: a case series and literature review.
Topics: Acetaminophen; Administration, Oral; Analgesics, Opioid; Chemistry, Pharmaceutical; Codeine; Drug Co | 2020 |
Benzhydrocodone/acetaminophen (Apadaz) for pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Combinations; Humans; Hydrocodone; | 2019 |
Management of opioid painkiller dependence in primary care: ongoing recovery with buprenorphine/naloxone.
Topics: Acetaminophen; Analgesics, Opioid; Buprenorphine; Chronic Pain; Codeine; Counseling; Fatigue Syndrom | 2014 |
[Treatment of acute pain during drug-assisted rehabilitation].
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents | 2010 |
Treatment of chronic pain in osteoarthritis: do opioids have a clinical role?
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Opioid-Related D | 2001 |
6 trials available for acetaminophen and Addiction, Opioid
| Article | Year |
|---|---|
HTX-011 in Combination with Multimodal Analgesic Regimen Minimized Severe Pain and Opioid Use after Total Knee Arthroplasty in an Open-Label Study.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; | 2023 |
A randomized pilot program to reduce opioid use following dental surgery and increase safe medication return.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; Male; | 2020 |
Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Cesarean Section; Female; Humans; Ibuprofen; Opioid-Relate | 2021 |
Pharmacokinetics and Abuse Potential of Benzhydrocodone, a Novel Prodrug of Hydrocodone, After Intranasal Administration in Recreational Drug Users.
Topics: Acetaminophen; Administration, Intranasal; Adult; Analgesics, Opioid; Cross-Over Studies; Double-Bli | 2018 |
Opioid Use following Outpatient Breast Surgery: Are Physicians Part of the Problem?
Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Drug Combinations; D | 2018 |
Pharmacokinetics of hydrocodone extended-release tablets formulated with different levels of coating to achieve abuse deterrence compared with a hydrocodone immediate-release/acetaminophen tablet in healthy subjects.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Chemistry, Pharmaceutical; Cross-Over Studies; Delayed-Act | 2015 |
61 other studies available for acetaminophen and Addiction, Opioid
| Article | Year |
|---|---|
JK.
Topics: Accidents, Traffic; Acetaminophen; Analgesics, Opioid; Anxiety; Drug Combinations; Family Relations; | 2021 |
Association of Intravenous Acetaminophen Administration With the Duration of Intravenous Opioid Use Among Hospitalized Pediatric Patients.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, | 2021 |
Perioperative Multimodal Pain Management Approach in Older Adults With Polytrauma.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Humans; Multiple Trauma; Opioid-Related Disorders; Pain Man | 2022 |
Enhanced Recovery after Surgery Protocol to Improve Racial and Ethnic Disparities in Postcesarean Pain Management.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Celecoxib; Endrin; Enhanced | 2022 |
Standing Intravenous Acetaminophen Is Associated With a Reduction of Post-operative Opioid Use in Infants Aged Less Than 1 Year Treated on the Acute Care Floor.
Topics: Acetaminophen; Analgesics, Opioid; Humans; Opiate Alkaloids; Opioid-Related Disorders; Pain, Postope | 2022 |
Opioid Consumption After Urogynecologic Surgery: A Prospective Multicenter Observational Study Using a Text-Messaging Survey Tool.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Female; Humans; Ibuprof | 2022 |
A Prospective Analysis of Opioid Use Following Outpatient Pediatric Urologic Surgery.
Topics: Acetaminophen; Analgesics, Opioid; Child; Child, Preschool; Female; Humans; Ibuprofen; Male; Opioid- | 2022 |
Pain management after microtia repair with costal cartilage: De-escalation and opioid use reduction.
Topics: Acetaminophen; Analgesics, Opioid; Child; Congenital Microtia; Costal Cartilage; Humans; Narcotics; | 2022 |
Pediatric Hip Disease Increases the Risk for Opioid Use in Adulthood: Long-term Burden of Pain and Depression.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents; Antidepressive Agent | 2022 |
Screening the "Invisible Population" of Older Adult Patients for Prescription Pain Reliever Non-Medical Use and Use Disorders.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Humans; Opioid-Related Disorders; Pain; Prescri | 2023 |
Screening the "Invisible Population" of Older Adult Patients for Prescription Pain Reliever Non-Medical Use and Use Disorders.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Humans; Opioid-Related Disorders; Pain; Prescri | 2023 |
Screening the "Invisible Population" of Older Adult Patients for Prescription Pain Reliever Non-Medical Use and Use Disorders.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Humans; Opioid-Related Disorders; Pain; Prescri | 2023 |
Screening the "Invisible Population" of Older Adult Patients for Prescription Pain Reliever Non-Medical Use and Use Disorders.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Humans; Opioid-Related Disorders; Pain; Prescri | 2023 |
Liposomal Bupivacaine Decreases Intravenous Opioid Use in Patients with Hip Fracture: A Modification to a Novel Pain Protocol.
Topics: Acetaminophen; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Delirium; Hip | 2023 |
Impact of dexmedetomidine in conjunction with a weaning protocol on post-surgical opioid use in a neonatal intensive care unit.
Topics: Acetaminophen; Analgesics, Opioid; Clonidine; Dexmedetomidine; Humans; Infant, Newborn; Intensive Ca | 2023 |
An opioid-minimizing multimodal pain regimen reduces opioid exposure and pain in trauma-injured patients at high risk for opioid misuse: Secondary analysis from the mast trial.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Bayes Theorem; Gabapentin; Humans; Morphine Derivativ | 2023 |
Implementation of a Multimodal Pain Management Order Set Reduces Perioperative Opioid Use after Liver Transplantation.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Drug Therapy, Combination; Female; Gabapentin; | 2019 |
Operating without opioids.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Celecoxib; Drug Combinations; Drug Prescriptions; Gen | 2019 |
Identification of factors influencing tampering of codeine-containing medicines in England: a qualitative study.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Codeine; Drug Combinatio | 2020 |
Opioid Misuse Among American Indian Adolescents.
Topics: Acetaminophen; Adolescent; Adolescent Behavior; Drug Combinations; Female; Humans; Hydrocodone; Indi | 2021 |
Opioid use after cesarean: a cohort study comparing combined versus separate oxycodone and acetaminophen regimens.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Female; Humans; | 2022 |
Underutilization of Acetaminophen in Older Adult Trauma Patients.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans | 2022 |
A standardized post-cesarean analgesia regimen reduces postpartum opioid use.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Human | 2022 |
Patients at Risk: Large Opioid Prescriptions After Total Knee Arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Drug Co | 2017 |
In Response: The Contribution of the Emergency Department to Opioid Pain Reliever Misuse and Diversion: A Critical Review.
Topics: Acetaminophen; Analgesics, Opioid; Emergency Service, Hospital; Humans; Opioid-Related Disorders; Pa | 2017 |
Relative Bioavailability, Intranasal Abuse Potential, and Safety of Benzhydrocodone/Acetaminophen Compared with Hydrocodone Bitartrate/Acetaminophen in Recreational Drug Abusers.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Biological Availability; Double-Blind Method; Drug Combina | 2018 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Response to Letter to the Editor The Contribution of the Emergency Department to Opioid Pain Reliever Misuse and Diversion: A Critical Review.
Topics: Acetaminophen; Analgesics, Opioid; Emergency Service, Hospital; Humans; Opioid-Related Disorders; Pa | 2017 |
Opioids for Acute Pain: Proceed with Caution.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Opioid; Chronic Pain; Drug Combinations; Female; Fract | 2018 |
Continuous local bupivacaine wound infusion with neuraxial morphine reduces opioid consumption after cesarean delivery.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, S | 2019 |
Opioid Prescribing Practices of Orthopaedic Surgeons: Results of a National Survey.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Female; Humans; Hydrocodone; Male; Online Systems; Op | 2019 |
Multimodal Postoperative Pain Control Is Effective and Reduces Opioid Use After Laparoscopic Roux-en-Y Gastric Bypass.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics, Opioid; Breakthrough Pain; Celecoxib; | 2019 |
Adolescent Nonmedical Use of Opioids and Alcohol Mixed with Energy Drinks.
Topics: Acetaminophen; Adolescent; Adolescent Behavior; Alcohol Drinking; Analgesics, Opioid; Drinking Behav | 2018 |
Case 6-2019: A 29-Year-Old Woman with Nausea, Vomiting, and Diarrhea.
Topics: Acetaminophen; Adult; Buprenorphine; Cocaine-Related Disorders; Diagnosis, Differential; Diarrhea; D | 2019 |
Parents' attitudes toward post-operative narcotic use in pediatric patients.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Caregivers; Child; Child, Preschool; Female; He | 2019 |
Acute pain control challenges with buprenorphine/naloxone therapy in a patient with compartment syndrome secondary to McArdle's disease: a case report and review.
Topics: Acetaminophen; Acute Pain; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
Elevated acetaminophen concentration measured after nasal insufflation of Percocet®.
Topics: Acetaminophen; Acetylcysteine; Administration, Intranasal; Adult; Drug Combinations; Drug Overdose; | 2013 |
Rational prescribing.
Topics: Acetaminophen; Analgesics, Opioid; Chronic Pain; Drug Combinations; Humans; Long-Term Care; Minnesot | 2013 |
Marked variability in peri-partum anesthetic management of patients on buprenorphine maintenance therapy (BMT): can there be an underlying acute opioid induced hyperalgesia precipitated by neuraxial opioids in BMT patients?
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Buprenorphine; Cesarea | 2013 |
Monitoring of internet forums to evaluate reactions to the introduction of reformulated OxyContin to deter abuse.
Topics: Acetaminophen; Analgesics, Opioid; Chemistry, Pharmaceutical; Drug Combinations; Humans; Hydrocodone | 2014 |
Patient recall of health care provider counseling for opioid-acetaminophen prescriptions.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Counseling; Cross-Sectional Studies; Drug Combinations; Fe | 2014 |
Clinical and pathologic characteristics of intranasal abuse of combined opioid-acetaminophen medications.
Topics: Acetaminophen; Administration, Intranasal; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid | 2014 |
DEA reschedules hydrocodone combination products.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Attitude to Health; Drug and Narcotic Control; Drug C | 2015 |
The Potential Role of an Extended-Release, Abuse-Deterrent Oxycodone/Acetaminophen Fixed-Dose Combination Product for the Treatment of Acute Pain.
Topics: Acetaminophen; Acute Pain; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Chemistry, Phar | 2015 |
Evaluation of the tamper-resistant properties of biphasic immediate-release/extended-release oxycodone/acetaminophen tablets.
Topics: Acetaminophen; Acute Pain; Administration, Intranasal; Analgesics, Opioid; Chronic Pain; Delayed-Act | 2016 |
The Canary in the Coal Mine Tweets: Social Media Reveals Public Perceptions of Non-Medical Use of Opioids.
Topics: Acetaminophen; Analgesics, Opioid; Attitude to Health; Communication; Data Collection; Drug Combinat | 2015 |
Safety Issues Regarding Prescription Opioids.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Combinations; Drug Overdose; Drug | 2016 |
The impact of codeine re-scheduling on misuse: a retrospective review of calls to Australia's largest poisons centre.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Codeine; Drug Combinations; Female; Humans; Ibuprofen; Mal | 2016 |
Discordant reporting of nonmedical opioid use in a nationally representative sample of US high school seniors.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Drug Combinations; Female; Humans; Hydrocodone; Male; | 2016 |
Profound hearing loss associated with oxycodone-acetaminophen abuse.
Topics: Acetaminophen; Drug Combinations; Female; Hearing Loss, Sensorineural; Humans; Middle Aged; Opioid-R | 2008 |
Profound metabolic acidosis from pyroglutamic acidemia: an underappreciated cause of high anion gap metabolic acidosis.
Topics: Acetaminophen; Acid-Base Equilibrium; Acidosis; Adult; Diagnosis, Differential; Female; Humans; Opio | 2010 |
Case scenario: self-extraction of intrathecal pump medication with a concomitant intrathecal granulomatous mass.
Topics: Acetaminophen; Administration, Cutaneous; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, O | 2011 |
Prescribing recommendations for the treatment of acute pain in dentistry.
Topics: Acetaminophen; Acute Disease; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroida | 2011 |
Rectal ulcer induced by suppositories.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Codeine; Drug Combin | 2011 |
Intranasal hydrocodone-acetaminophen abuse induced necrosis of the nasal cavity and pharynx.
Topics: Acetaminophen; Administration, Intranasal; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroid | 2012 |
My story: how one Percocet prescription triggered my addiction.
Topics: Acetaminophen; Behavior, Addictive; Drug Combinations; Humans; Nursing Staff, Hospital; Opioid-Relat | 2012 |
Prescription patterns of pain medicine physicians.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Drug Prescriptions; Humans; Methadone; Opioid-Related | 2013 |
A message of hope.
Topics: Acetaminophen; Dentists; Drug Combinations; Humans; Hydrocodone; Massachusetts; Narcotics; Opioid-Re | 2004 |
Rates of abuse of tramadol remain unchanged with the introduction of new branded and generic products: results of an abuse monitoring system, 1994-2004.
Topics: Acetaminophen; Analgesics, Opioid; Drug Prescriptions; Drugs, Generic; Humans; Narcotics; Opioid-Rel | 2005 |
Opioids for non-operable osteoarthritis and soft-tissue rheumatism.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, | 2005 |
The Diversion of Ultram, Ultracet, and generic tramadol HCL.
Topics: Acetaminophen; Advisory Committees; Cross-Sectional Studies; Data Collection; Drug and Narcotic Cont | 2006 |
Safety of codeine during breastfeeding: fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine.
Topics: Acetaminophen; Analgesics, Opioid; Breast Feeding; Codeine; Cytochrome P-450 CYP2D6; Fatal Outcome; | 2007 |
Complete soft palate necrosis and velopharyngeal insufficiency resulting from intranasal inhalation of prescription narcotics and cocaine.
Topics: Acetaminophen; Administration, Inhalation; Adult; Analgesics, Opioid; Cocaine; Cocaine-Related Disor | 2007 |
Dextropropoxyphene deaths: coroner's report.
Topics: Acetaminophen; Adult; Alcoholism; Dextropropoxyphene; Drug Combinations; Humans; Middle Aged; Opioid | 1984 |