acetaminophen has been researched along with Acute-Phase Reaction in 6 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Acute-Phase Reaction: An early local inflammatory reaction to insult or injury that consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mechanism(s) of liver damage initiated by ingestion of toxic components of thermally oxidized lipids was compared in a rat model with the documented mechanisms of hepatic failure and necrosis initiated by acetaminophen." | 3.69 | Comparison of thermally oxidized lipids and acetaminophen with concurrent consumption of ethanol as inducers of liver cirrhosis. ( Fouad, FM; Mamer, OA; Shahidi, F, 1995) |
| "Acetaminophen (APAP) is a safe analgesic and antipyretic drug." | 1.38 | Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure. ( Amaral, SS; Avila, TV; Cara, DC; De Paula, AM; Leite, MF; Lima, BH; Lima, CX; Lopes, GA; Marques, PE; Melgaço, JG; Menezes, GB; Nogueira, LL; Oliveira, AG; Pinto, MA; Pires, DA; Russo, RC; Soriani, FM; Teixeira, MM, 2012) |
| "Fever is a part of the acute phase response, a generalized reaction to infection or inflammation initiated by interleukin-1 (IL-1)." | 1.27 | Fever. What to do and what not to do. ( Rosenthal, TC; Silverstein, DA, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Srivastava, T | 1 |
| Haney, CJ | 1 |
| Alon, US | 1 |
| Silverman, SL | 1 |
| Kriegman, A | 1 |
| Goncalves, J | 1 |
| Kianifard, F | 1 |
| Carlson, T | 1 |
| Leary, E | 1 |
| Marques, PE | 1 |
| Amaral, SS | 1 |
| Pires, DA | 1 |
| Nogueira, LL | 1 |
| Soriani, FM | 1 |
| Lima, BH | 1 |
| Lopes, GA | 1 |
| Russo, RC | 1 |
| Avila, TV | 1 |
| Melgaço, JG | 1 |
| Oliveira, AG | 1 |
| Pinto, MA | 1 |
| Lima, CX | 1 |
| De Paula, AM | 1 |
| Cara, DC | 1 |
| Leite, MF | 1 |
| Teixeira, MM | 1 |
| Menezes, GB | 1 |
| Fouad, FM | 1 |
| Shahidi, F | 1 |
| Mamer, OA | 1 |
| Izumi, S | 1 |
| Hughes, RD | 1 |
| Langley, PG | 1 |
| Pernambuco, JR | 1 |
| Williams, R | 1 |
| Rosenthal, TC | 1 |
| Silverstein, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use of Atorvastatin (Lipitor) to Prevent Bone Pain Following Infusion of Pamidronate or Zoledronic Acid[NCT00120133] | 12 participants (Actual) | Interventional | 2004-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for acetaminophen and Acute-Phase Reaction
| Article | Year |
|---|---|
Atorvastatin may have no effect on acute phase reaction in children after intravenous bisphosphonate infusion.
Topics: Acetaminophen; Acute-Phase Reaction; Anticholesteremic Agents; Atorvastatin; Bone Density Conservati | 2009 |
Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid.
Topics: Acetaminophen; Acute-Phase Reaction; Aged; Antipyretics; Bone Density Conservation Agents; Diphospho | 2011 |
4 other studies available for acetaminophen and Acute-Phase Reaction
| Article | Year |
|---|---|
Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure.
Topics: Acetaminophen; Acute Lung Injury; Acute-Phase Reaction; Adolescent; Adult; Analysis of Variance; Ani | 2012 |
Comparison of thermally oxidized lipids and acetaminophen with concurrent consumption of ethanol as inducers of liver cirrhosis.
Topics: Acetaminophen; Acute-Phase Reaction; Analysis of Variance; Animals; Benzoquinones; DNA; Drug Interac | 1995 |
Extent of the acute phase response in fulminant hepatic failure.
Topics: Acetaminophen; Acute-Phase Reaction; Adolescent; Adult; alpha 1-Antitrypsin; Bacterial Infections; C | 1994 |
Fever. What to do and what not to do.
Topics: Acetaminophen; Acute-Phase Reaction; Aspirin; Body Temperature Regulation; Cold Temperature; Fever; | 1988 |