Compounds > acetaminophen
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acetaminophen and Acute Kidney Tubular Necrosis

acetaminophen has been researched along with Acute Kidney Tubular Necrosis in 28 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
" Physicians should be aware of potential hepatotoxicity and nephrotoxicity of acetaminophen, even if given at therapeutic dosage in acute febrile illness."1.34Therapeutic dose of acetaminophen with fatal hepatic necrosis and acute renal failure. ( Lohachit, P; Ruamvang, T; Satirapoj, B, 2007)
"We report two cases of acute renal failure following paracetamol (acetaminophen) poisoning."1.27Paracetamol (acetaminophen) poisoning resulting in acute renal failure without hepatic coma. ( Davenport, A; Finn, R, 1988)
"Seven patients with acute renal failure after ingestion of analgesic drug combinations including paracetamol were seen."1.27Acute renal failure after analgesic drugs including paracetamol (acetaminophen). ( Aurell, M; Björck, S; Svalander, CT, 1988)
"Reversible acute renal failure of unknown cause occurred in two men after taking paracetamol in therapeutic doses."1.26Acute tubular necrosis, caused by therapeutic doses of paracetamol? ( Caldwell, J; Gabriel, R; Hartley, RB, 1982)
"It is concluded that acute renal failure without prior hepatic failure may occur after acetaminophen overdose."1.26Acute renal failure after acetaminophen overdose: report of two cases. ( Jeffery, WH; Lafferty, WE, 1981)
"Phenacetin pretreatment (597 mg/kg) was less effective, while paracetamol (503 mg/kg) was without effect in this regard."1.26Studies on the modification of renal lesions due to aspirin and oxyphenbutazone in the rat and the effects on the kidney of 2:4 dinitrophenol. ( Arnold, L; Collins, C; Starmer, GA, 1976)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199019 (67.86)18.7374
1990's3 (10.71)18.2507
2000's5 (17.86)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Le Vaillant, J1
Pellerin, L1
Brouard, J1
Eckart, P1
Bonati, M1
Humphreys, BD1
Forman, JP1
Zandi-Nejad, K1
Bazari, H1
Seifter, J1
Magee, CC1
Satirapoj, B1
Lohachit, P1
Ruamvang, T1
Henry, MA1
Sweet, RS1
Tange, JD1
Stegeman-Castelen, G1
van Hattum, J1
Koomans, HA1
de Vries, J1
van Heijst, AN1
Gabriel, R1
Caldwell, J1
Hartley, RB1
Jeffery, WH1
Lafferty, WE1
Kleinman, JG1
Breitenfield, RV1
Roth, DA1
von Mühlendahl, KE1
Krienke, EG1
Jákó, J1
Arató, G1
Nasir, AK1
Walburn, J1
Alkhuja, S1
Aboudan, M1
Menkel, R1
Herrero, JL1
Castellano, I1
Gómez-Martino, JR1
Novillo, R1
Covarsí, A1
Mitchell, JR1
McMurtry, RJ1
Statham, CN1
Nelson, SD1
McJunkin, B1
Barwick, KW1
Little, WC1
Winfield, JB1
Arnold, L1
Collins, C1
Starmer, GA1
Emeigh Hart, SG1
Beierschmitt, WP2
Bartolone, JB1
Wyand, DS1
Khairallah, EA1
Cohen, SD1
Kleinknecht, D1
Landais, P1
Goldfarb, B1
Tarloff, JB1
Goldstein, RS1
Morgan, DG1
Hook, JB1
Davenport, A1
Finn, R1
McClain, CJ1
Holtzman, J1
Allen, J1
Kromhout, J1
Shedlofsky, S1
Björck, S1
Svalander, CT1
Aurell, M1
Keaton, MR1
Sørensen, FB1
Landbo, B1
Marcussen, N1
Keenan, KP1
Weiner, M1
Kaysen, GA1
Pond, SM1
Roper, MH1
Menke, DJ1
Marrama, MA1

Reviews

1 review available for acetaminophen and Acute Kidney Tubular Necrosis

ArticleYear
[Amidazophen. Yes or no?].
    Orvosi hetilap, 1995, Sep-24, Volume: 136, Issue:39

    Topics: Acetaminophen; Adult; Aminopyrine; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal

1995

Other Studies

27 other studies available for acetaminophen and Acute Kidney Tubular Necrosis

ArticleYear
[Acetaminophen (paracetamol) causing renal failure: report on 3 pediatric cases].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2013, Volume: 20, Issue:6

    Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Creatinine; Drug Overdose; Female; Follow-Up Studies

2013
Once again, children are the main victims of fake drugs.
    Archives of disease in childhood, 2009, Volume: 94, Issue:6

    Topics: Acetaminophen; Child; Child, Preschool; Developing Countries; Drug Contamination; Ethylene Glycols;

2009
Acetaminophen-induced anion gap metabolic acidosis and 5-oxoprolinuria (pyroglutamic aciduria) acquired in hospital.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:1

    Topics: Acetaminophen; Acid-Base Equilibrium; Acidosis; Adult; Analgesics, Non-Narcotic; Antineoplastic Comb

2005
Therapeutic dose of acetaminophen with fatal hepatic necrosis and acute renal failure.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2007, Volume: 90, Issue:6

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Analgesics, Non-Narcotic; Autopsy; Fatal Outcome; Female;

2007
A new reproducible experimental model of analgesic nephropathy.
    The Journal of pathology, 1983, Volume: 139, Issue:1

    Topics: Acetaminophen; Analgesics; Animals; Antipyrine; Aspirin; Disease Models, Animal; Female; Kidney; Kid

1983
[Acute kidney insufficiency following paracetamol poisoning].
    Nederlands tijdschrift voor geneeskunde, 1983, Jun-11, Volume: 127, Issue:24

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Female; Humans; Kidney Tubular Necrosis, Acute; Kidney Tu

1983
Acute tubular necrosis, caused by therapeutic doses of paracetamol?
    Clinical nephrology, 1982, Volume: 18, Issue:5

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Biopsy; Humans; Kidney; Kidney Tubular Necrosis, Acute; M

1982
Acute renal failure after acetaminophen overdose: report of two cases.
    American journal of hospital pharmacy, 1981, Volume: 38, Issue:9

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Female; Humans; Kidney Tubular Necrosis, Acute

1981
Acute renal failure associated with acetaminophen ingestion: report of a case and review of the literature.
    Clinical nephrology, 1980, Volume: 14, Issue:4

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Humans; Kidney; Kidney Tubular Necrosis, Acute; Liver; Ma

1980
[Paracetamol poisoning].
    Intensivmedizinische Praxis, 1980, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; I

1980
Poisoning with acetaminophen "jello".
    Pediatrics, 1997, Volume: 99, Issue:4

    Topics: Acetaminophen; Child; Humans; Kidney Tubular Necrosis, Acute; Male

1997
Acetaminophen toxicity induced non-oliguric acute tubular necrosis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:1

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Female; Humans; Kidney

2001
[Acute kidney failure caused by paracetamol poisoning].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2001, Volume: 21, Issue:6

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Blood Coagulation Tests; Chemical and Drug Induced Liver

2001
Letter: Paracetamol hepatotoxicity.
    Lancet (London, England), 1976, Jan-03, Volume: 1, Issue:7949

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Death, Sudden; Humans; Kidney Tubular Necrosi

1976
Molecular basis for several drug-induced nephropathies.
    The American journal of medicine, 1977, Volume: 62, Issue:4

    Topics: Acetaminophen; Analgesics; Animals; Carbon Tetrachloride Poisoning; Cephaloridine; Chloroform; Cytoc

1977
Fatal massive hepatic necrosis following acetaminophen overdose.
    JAMA, 1976, Oct-18, Volume: 236, Issue:16

    Topics: Acetaminophen; Adult; Autopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Kidney; Kidne

1976
Studies on the modification of renal lesions due to aspirin and oxyphenbutazone in the rat and the effects on the kidney of 2:4 dinitrophenol.
    Pathology, 1976, Volume: 8, Issue:3

    Topics: Acetaminophen; Acute Kidney Injury; Animals; Aspirin; Dinitrophenols; Female; Kidney Tubular Necrosi

1976
Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse.
    Toxicology and applied pharmacology, 1991, Volume: 107, Issue:1

    Topics: Acetaminophen; Acetylation; Aminophenols; Animals; Blood Urea Nitrogen; Cytochrome P-450 Enzyme Inhi

1991
Analgesic and non-steroidal anti-inflammatory drug-associated acute renal failure: a prospective collaborative study.
    Clinical nephrology, 1986, Volume: 25, Issue:6

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics; Anti-Inflammatory Agents; Biopsy; Female; Glafenine;

1986
Acetaminophen and p-aminophenol nephrotoxicity in aging male Sprague-Dawley and Fischer 344 rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1989, Volume: 12, Issue:1

    Topics: Acetaminophen; Aging; Aminophenols; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Kidn

1989
Paracetamol (acetaminophen) poisoning resulting in acute renal failure without hepatic coma.
    Nephron, 1988, Volume: 50, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Adult; Female; Hepatic Encephalopathy; Humans; K

1988
Clinical features of acetaminophen toxicity.
    Journal of clinical gastroenterology, 1988, Volume: 10, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Female; Humans

1988
Acute renal failure after analgesic drugs including paracetamol (acetaminophen).
    Nephron, 1988, Volume: 49, Issue:1

    Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Analgesics; Biopsy; Humans; Kidney; Kidney Tu

1988
Acute renal failure in an alcoholic during therapeutic acetaminophen ingestion.
    Southern medical journal, 1988, Volume: 81, Issue:9

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Alcoholism; Headache; Humans; Kidney Tubular Necrosis, Ac

1988
[Paracetamol poisoning with fatal necrosis of the liver].
    Ugeskrift for laeger, 1986, Oct-13, Volume: 148, Issue:42

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Female; Humans; Kidney Tubular Necrosis, Acut

1986
The development of acetaminophen-induced nephrotoxicity in male Fischer 344 rats of different ages.
    Archives of toxicology, 1986, Volume: 59, Issue:4

    Topics: Acetaminophen; Aging; Animals; Blood Urea Nitrogen; Glomerulonephritis; Kidney Diseases; Kidney Tubu

1986
Combined hepatic and renal injury in alcoholics during therapeutic use of acetaminophen.
    Archives of internal medicine, 1985, Volume: 145, Issue:11

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Diagn

1985