Page last updated: 2024-10-22

acetaminophen and Acute Hypercapnic Respiratory Failure

acetaminophen has been researched along with Acute Hypercapnic Respiratory Failure in 16 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
" The absolute bioavailability of frusemide during hypoxaemia (0."2.68The effect of hypoxaemia on drug disposition in chronic respiratory failure. ( Hayball, PJ; Henderson, G; Latimer, K; May, F; Rowett, D; Ruffin, RE; Sansom, LN, 1996)
"Death commonly involved multiple substance use and abuse behaviours indicative of misuse and dependence."1.48Unintentional mortality associated with paracetamol and codeine preparations, with and without doxylamine, in Australia. ( Dobbin, M; Hopkins, RE; Pilgrim, JL, 2018)
"We report two cases of fulminant hepatic failure caused by therapeutic (4 g x day(-1)) paracetamol administration on our Intensive Care Unit."1.35Acute liver failure following therapeutic paracetamol administration in patients with muscular dystrophies. ( Grant, IS; Pearce, B, 2008)
"The morphine was administered as a single bolus, following delivery, in doses ranging from 2 to 5 mg."1.28Epidural morphine for analgesia after caesarean section: a report of 4880 patients. ( Douglas, MJ; Fuller, JG; McMorland, GH; Palmer, L, 1990)
"Only 7 out of 71 patients with arrhythmias other than sinus tachycardia survived, compared with 15 out of 31 patients without them (P less than 0-005)."1.26Frequency of arrhythmias and other cardiac abnormalities in fulminant hepatic failure. ( Capildeo, R; Horoworth, PJ; Mant, AK; Talbot, IC; Weston, MJ; Williams, R, 1976)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's4 (25.00)18.2507
2000's3 (18.75)29.6817
2010's5 (31.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Lewald, H1
Girard, T1
Floyd, CN1
Dargan, PI1
Pruthi, S1
Shah, S1
Gambhir, HS1
Hopkins, RE1
Dobbin, M1
Pilgrim, JL1
Amathieu, R1
Levesque, E1
Merle, JC1
Chemit, M1
Costentin, C1
Compagnon, P1
Dhonneur, G1
Heppell, SPE1
Isbister, GK1
Beccaria, P1
Cabrini, L1
Garancini, MP1
Colombo, S1
Adam, F1
Pearce, B1
Grant, IS1
Rademaker, J1
Severs, M1
Rowett, D1
Latimer, K1
Sansom, LN1
Ruffin, RE1
May, F1
Henderson, G1
Hayball, PJ1
Talbott, GA1
Lynn, AM1
Levy, FH1
Zelikovic, I1
Weston, MJ1
Talbot, IC1
Horoworth, PJ1
Mant, AK1
Capildeo, R1
Williams, R2
Gazzard, BG1
Hughes, RD1
Mellon, PJ1
Portmann, B1
Fuller, JG1
McMorland, GH1
Douglas, MJ1
Palmer, L1
Rueff, B1
Benhamou, JP1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658]Phase 448 participants (Anticipated)Interventional2019-02-18Recruiting
Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section[NCT02410317]Phase 3101 participants (Actual)Interventional2015-02-28Completed
Randomized, Controlled, Double Blind, to Evaluate the Postpartum Analgesia With Epidural Morphine: Analgesic Effect of Two Different Doses Compared to Placebo[NCT04887649]Phase 3114 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for acetaminophen and Acute Hypercapnic Respiratory Failure

ArticleYear
Analgesia after cesarean section - what is new?
    Current opinion in anaesthesiology, 2023, Jun-01, Volume: 36, Issue:3

    Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Analgesics, Opioid; Cesarean Section; Female; Humans;

2023
[Severe toxic acute liver failure: etiology and treatment].
    Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Anti-Infective Agents; Blood Coagulation Disorde

2013
[Weak opioids. Pain and Locoregional Anesthesia Committee and the Standards Committee of the French Society of Anesthesia and Intensive Care].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:2

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injur

2009
Acute hepatic necrosis and fulminant hepatic failure.
    Gut, 1973, Volume: 14, Issue:10

    Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Animals; Blood Coagulation Disorders; Brain Dise

1973

Trials

1 trial available for acetaminophen and Acute Hypercapnic Respiratory Failure

ArticleYear
The effect of hypoxaemia on drug disposition in chronic respiratory failure.
    European journal of clinical pharmacology, 1996, Volume: 50, Issue:1-2

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Biological Availability; Chronic Disease; Cros

1996

Other Studies

11 other studies available for acetaminophen and Acute Hypercapnic Respiratory Failure

ArticleYear
The toxicity of paracetamol-codeine combination in overdose is an unresolved issue.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:4

    Topics: Acetaminophen; Codeine; Drug Combinations; Drug Overdose; Humans; Respiratory Insufficiency

2018
Laundry Blues: a case of methemoglobinemia with laundry detergent and Tylenol ingestion.
    QJM : monthly journal of the Association of Physicians, 2017, Sep-01, Volume: 110, Issue:9

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Bipolar Disorder; Brain Diseases; Detergent

2017
Unintentional mortality associated with paracetamol and codeine preparations, with and without doxylamine, in Australia.
    Forensic science international, 2018, Volume: 282

    Topics: Accidents; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Antiemetics; Austr

2018
Lack of respiratory depression in paracetamol-codeine combination overdoses.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Child; Codeine

2017
Recurarisation in a surgical ward.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:6

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, General; Anes

2008
Acute liver failure following therapeutic paracetamol administration in patients with muscular dystrophies.
    Anaesthesia, 2008, Volume: 63, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Humans; Liver Failure, Acute; Male; Muscular Dystrop

2008
Opiate related collapse in an octogenarian.
    BMJ (Clinical research ed.), 1993, Jul-24, Volume: 307, Issue:6898

    Topics: Acetaminophen; Aged; Aged, 80 and over; Codeine; Female; Humans; Respiratory Insufficiency

1993
Respiratory arrest precipitated by codeine in a child with chronic renal failure.
    Clinical pediatrics, 1997, Volume: 36, Issue:3

    Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Child, Preschool; Codein

1997
Frequency of arrhythmias and other cardiac abnormalities in fulminant hepatic failure.
    British heart journal, 1976, Volume: 38, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Brain; Child; Electrocardiography; Hea

1976
A dog model of fulminant hepatic failure produced by paracetamol administration.
    British journal of experimental pathology, 1975, Volume: 56, Issue:5

    Topics: Acetaminophen; Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Disease Models

1975
Epidural morphine for analgesia after caesarean section: a report of 4880 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:6

    Topics: Acetaminophen; Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean S

1990
Epidural morphine for analgesia after caesarean section: a report of 4880 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:6

    Topics: Acetaminophen; Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean S

1990
Epidural morphine for analgesia after caesarean section: a report of 4880 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:6

    Topics: Acetaminophen; Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean S

1990
Epidural morphine for analgesia after caesarean section: a report of 4880 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:6

    Topics: Acetaminophen; Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean S

1990