acetaminophen has been researched along with Absence Seizure in 31 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Eligible children will receive treatment allocation randomization either to standard of care for fever management or to prophylactic, scheduled treatment every 6 hours for 72 hours with dual antipyretic therapies using acetaminophen and ibuprofen." | 5.51 | Aggressive antipyretics in central nervous system malaria: Study protocol of a randomized-controlled trial assessing antipyretic efficacy and parasite clearance effects (Malaria FEVER study). ( Birbeck, GL; Chilombe, MB; Mathews, M; McDermott, MP; Mwenechanya, M; Seydel, KB, 2022) |
| " While dosing errors are common, in most cases, overdoses produce minimal clinical effects." | 5.37 | Massive acetylcysteine overdose associated with cerebral edema and seizures. ( Heard, K; Schaeffer, TH, 2011) |
| " Although it has been reported that AM404, a metabolite of acetaminophen, has anticonvulsant effects in several animal seizure models, little is known about the relation between acetaminophen and seizures." | 3.88 | Anticonvulsant effects of acetaminophen in mice: Comparison with the effects of nonsteroidal anti-inflammatory drugs. ( Araki, H; Aso, H; Suemaru, K; Tanaka, A; Watanabe, M; Yoshikawa, M, 2018) |
| " She also received phenytoin for posttraumatic seizures." | 3.70 | Phenytoin as a possible cause of acetaminophen hepatotoxicity: case report and review of the literature. ( Bloch, JD; Brackett, CC, 2000) |
| " The effect of Ciprofloxacin was studied in electroconvulsive seizures in mice using the tonic extensor phase as end point and seizure threshold as observational parameter." | 3.69 | Interaction of ciprofloxacin with diclofenac and paracetamol in relation to it's epileptogenic effect. ( Makde, SD; Paranjpe, BD; Shrivastava, MP, 1997) |
| "Recently, seizure-induced cyclooxygenase (COX)-mediated postictal vasoconstriction, accompanied by cerebral hypoperfusion and hypoxia, has been identified as a candidate mechanism in experimentally induced seizures in rats." | 3.11 | Study of effect of nimodipine and acetaminophen on postictal symptoms in depressed patients after electroconvulsive therapy (SYNAPSE). ( Hofmeijer, J; Pottkämper, JCM; van Putten, MJAM; van Waarde, JA; van Wingen, GA; Verdijk, JPAJ; Verwijk, E, 2022) |
| "Deficits in this task following seizures were reversed by COX-2 inhibition, which prevented severe postictal hypoxia." | 1.56 | In vivo assessment of mechanisms underlying the neurovascular basis of postictal amnesia. ( Colangeli, R; Dickson, CT; Dudok, B; Farrell, JS; Jackson, J; Nguyen, SL; Soltesz, I; Teskey, GC; Wolff, MD, 2020) |
| " While dosing errors are common, in most cases, overdoses produce minimal clinical effects." | 1.37 | Massive acetylcysteine overdose associated with cerebral edema and seizures. ( Heard, K; Schaeffer, TH, 2011) |
| "Through the next 5 hour seizure period and thereafter, the brain damage, liver damage enzyme values and hyperammonemia increased, particularly throughout the 3-24 h post-paracetamol period." | 1.36 | High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736). ( Anic, T; Boban Blagaic, A; Brcic, L; Coric, M; Djidic, S; Djuzel, V; Drmic, D; Ilic, S; Ivica, M; Klicek, R; Kolenc, D; Radic, B; Romic, Z; Seiwerth, S; Sever, M; Sikiric, P; Zarkovic, K; Zoricic, I; Zoricic, Z, 2010) |
| "Pallor was significantly more frequent after the first dose of whole cell pertussis than after acellulair pertussis vaccination (18." | 1.35 | Reactogenicity of infant whole cell pertussis combination vaccine compared with acellular pertussis vaccines with or without simultaneous pneumococcal vaccine in the Netherlands. ( David, S; van der Maas, NA; Vermeer-de Bondt, PE, 2008) |
| "When post-ischemic seizures ensued in hyperglycemic subjects, temperature was 39." | 1.29 | Preischemic hyperglycemia leads to delayed postischemic hyperthermia. ( Lundgren, J; Siesjö, BK; Smith, ML; Uchino, H, 1994) |
| "The reasons given for treating fever were to make the child comfortable (99%), to prevent seizures (63%), and to satisfy parents (44%)." | 1.27 | House officer management of the febrile child. A survey. ( Herskowitz, L; Weiss, J, 1983) |
| "The frequency of sound-induced seizures after 12." | 1.26 | Reduction in caffeine toxicity by acetaminophen. ( Deng, JF; Rall, TW; Spyker, DA; Steward, O, 1982) |
| " Acetaminophen and diazepam seemed to be well absorbed from the rectal suppositories, the maximal plasma concentration of diazepam after a rectal dose of 0." | 1.26 | Antipyretic effect and plasma concentrations of rectal acetaminophen and diazepam in children. ( Kangas, L; Keinänen-Kiukaanniemi, S; Luoma, P; Saukkonen, AL; Similä, S, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (38.71) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 7 (22.58) | 24.3611 |
| 2020's | 6 (19.35) | 2.80 |
| Authors | Studies |
|---|---|
| Verdijk, JPAJ | 1 |
| Pottkämper, JCM | 1 |
| Verwijk, E | 1 |
| van Wingen, GA | 1 |
| van Putten, MJAM | 1 |
| Hofmeijer, J | 1 |
| van Waarde, JA | 1 |
| Isbister, GK | 1 |
| Polanski, R | 1 |
| Cooper, JM | 1 |
| Keegan, M | 1 |
| Isoardi, KZ | 1 |
| Sha, L | 1 |
| Li, G | 1 |
| Zhang, X | 1 |
| Lin, Y | 1 |
| Qiu, Y | 1 |
| Deng, Y | 1 |
| Zhu, W | 1 |
| Xu, Q | 1 |
| Chilombe, MB | 1 |
| McDermott, MP | 1 |
| Seydel, KB | 1 |
| Mathews, M | 1 |
| Mwenechanya, M | 1 |
| Birbeck, GL | 1 |
| Alonso-Castro, AJ | 1 |
| Zapata-Morales, JR | 1 |
| Solorio-Alvarado, C | 1 |
| Hernández-Santiago, A | 1 |
| Espinoza-Ramírez, LA | 1 |
| Carranza-Álvarez, C | 1 |
| Ramadoss, V | 1 |
| Farrell, JS | 1 |
| Colangeli, R | 1 |
| Dudok, B | 1 |
| Wolff, MD | 1 |
| Nguyen, SL | 1 |
| Jackson, J | 1 |
| Dickson, CT | 1 |
| Soltesz, I | 1 |
| Teskey, GC | 1 |
| Suemaru, K | 2 |
| Yoshikawa, M | 2 |
| Tanaka, A | 1 |
| Araki, H | 1 |
| Aso, H | 2 |
| Watanabe, M | 2 |
| Brandehoff, NP | 1 |
| Baker, KA | 1 |
| Bonney, CF | 1 |
| Ng, PC | 1 |
| Schimmel, J | 1 |
| Hoyte, CO | 1 |
| Vyas, D | 1 |
| Lackey, G | 1 |
| McCulloh, RJ | 1 |
| Vilela, LR | 1 |
| Gomides, LF | 1 |
| David, BA | 1 |
| Antunes, MM | 1 |
| Diniz, AB | 1 |
| Moreira, Fde A | 1 |
| Menezes, GB | 1 |
| David, S | 1 |
| Vermeer-de Bondt, PE | 1 |
| van der Maas, NA | 1 |
| Ilic, S | 1 |
| Drmic, D | 1 |
| Zarkovic, K | 1 |
| Kolenc, D | 1 |
| Coric, M | 1 |
| Brcic, L | 1 |
| Klicek, R | 1 |
| Radic, B | 1 |
| Sever, M | 1 |
| Djuzel, V | 1 |
| Ivica, M | 1 |
| Boban Blagaic, A | 1 |
| Zoricic, Z | 1 |
| Anic, T | 1 |
| Zoricic, I | 1 |
| Djidic, S | 1 |
| Romic, Z | 1 |
| Seiwerth, S | 1 |
| Sikiric, P | 1 |
| Heard, K | 1 |
| Schaeffer, TH | 1 |
| Ashtekar, CS | 1 |
| Vyas, H | 1 |
| GARCIAHERRERA, E | 1 |
| Deng, JF | 1 |
| Spyker, DA | 1 |
| Rall, TW | 1 |
| Steward, O | 1 |
| Kang, ES | 1 |
| Olson, G | 1 |
| Jabbour, JT | 1 |
| Solomon, SS | 1 |
| Heimberg, M | 1 |
| Sabesin, S | 1 |
| Griffith, JF | 1 |
| Weiss, J | 1 |
| Herskowitz, L | 1 |
| Uchino, H | 1 |
| Lundgren, J | 1 |
| Smith, ML | 1 |
| Siesjö, BK | 1 |
| Shrivastava, MP | 1 |
| Makde, SD | 1 |
| Paranjpe, BD | 1 |
| Brackett, CC | 1 |
| Bloch, JD | 1 |
| Keinänen-Kiukaanniemi, S | 1 |
| Similä, S | 1 |
| Luoma, P | 1 |
| Kangas, L | 1 |
| Saukkonen, AL | 1 |
| Wallenstein, MC | 2 |
| Bito, LZ | 1 |
| Boréus, LO | 1 |
| Pegelow, CH | 1 |
| Goulden, KJ | 1 |
| Done, AK | 2 |
| Temple, AR | 1 |
| Meloff, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| StudY of Effect of Nimodipine and Acetaminophen on Postictal Symptoms After ECT[NCT04028596] | Phase 2 | 34 participants (Actual) | Interventional | 2019-12-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetaminophen and Absence Seizure
| Article | Year |
|---|---|
Treatment of salicylate poisoning.
Topics: Acetaminophen; Acid-Base Equilibrium; Acidosis; Acute Kidney Injury; Alkalosis, Respiratory; Aspirin | 1971 |
2 trials available for acetaminophen and Absence Seizure
| Article | Year |
|---|---|
Study of effect of nimodipine and acetaminophen on postictal symptoms in depressed patients after electroconvulsive therapy (SYNAPSE).
Topics: Acetaminophen; Animals; Depressive Disorder, Major; Electroconvulsive Therapy; Electroencephalograph | 2022 |
Aggressive antipyretics in central nervous system malaria: Study protocol of a randomized-controlled trial assessing antipyretic efficacy and parasite clearance effects (Malaria FEVER study).
Topics: Acetaminophen; Animals; Antipyretics; Central Nervous System; Child; Fever; Histidine; Humans; Ibupr | 2022 |
28 other studies available for acetaminophen and Absence Seizure
| Article | Year |
|---|---|
Duloxetine overdose causes sympathomimetic and serotonin toxicity without major complications.
Topics: Acetaminophen; Adult; Antidepressive Agents; Arrhythmias, Cardiac; Coma; Diazepam; Droperidol; Drug | 2022 |
Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice.
Topics: Acetaminophen; Animals; Anticonvulsants; Epilepsy; Epilepsy, Temporal Lobe; Excitatory Amino Acid Tr | 2022 |
Central nervous system evaluation of an ethanol extract of Bidens odorata Cav (Asteraceae) leaves, and its antinociceptive interaction with paracetamol and naproxen.
Topics: Acetaminophen; Analgesics; Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Ast | 2020 |
In vivo assessment of mechanisms underlying the neurovascular basis of postictal amnesia.
Topics: Acetaminophen; Amnesia; Animals; CA1 Region, Hippocampal; Hippocampus; Hypoxia; Long-Term Potentiati | 2020 |
Anticonvulsant effects of acetaminophen in mice: Comparison with the effects of nonsteroidal anti-inflammatory drugs.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Cyclooxygenase Inh | 2018 |
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Topics: Acetaminophen; Animals; Cannabinoids; Chemical and Drug Induced Liver Injury; Firearms; Humans; Lead | 2018 |
TRPV1 mediates the anticonvulsant effects of acetaminophen in mice.
Topics: Acetaminophen; Acetanilides; Acrylamides; Animals; Anticonvulsants; Bridged Bicyclo Compounds, Heter | 2018 |
Acute overdose: suicide attempt.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Antidotes; Charcoal; Diphenhydramine; Drug Overdose; Educ | 2013 |
Cannabidiol rescues acute hepatic toxicity and seizure induced by cocaine.
Topics: Acetaminophen; Alanine Transaminase; Animals; Cannabidiol; Cocaine; Inflammation; Liver; Male; Mice; | 2015 |
Reactogenicity of infant whole cell pertussis combination vaccine compared with acellular pertussis vaccines with or without simultaneous pneumococcal vaccine in the Netherlands.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Crying; Data Collection; Data Interpretation, Statistical; | 2008 |
High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736).
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Ulcer Agents; Antidotes; Brain; Dose-Response | 2010 |
Massive acetylcysteine overdose associated with cerebral edema and seizures.
Topics: Acetaminophen; Acetylcysteine; Adult; Brain Edema; Drug Overdose; Female; Humans; Medication Errors; | 2011 |
Warning note on a blood gas report leading to diagnosis of acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Analgesics, Non-Narcotic; Blood Glucose; Dextropropoxyphe | 2003 |
[RECTAL USE OF NAPA AS ANTIPYRETIC IN PEDIATRICS].
Topics: Acetaminophen; Antipyretics; Bronchitis; Child; Drug Therapy; Fever; Gastroenteritis; Humans; Infant | 1964 |
Reduction in caffeine toxicity by acetaminophen.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Acetaminophen; Acoustic Stimulation; Adenosine; Adult; A | 1982 |
Development of encephalopathic features similar to Reye syndrome in rabbits.
Topics: Acetaminophen; Animals; Aspirin; Disease Models, Animal; Encephalitis; Fatty Acids, Nonesterified; F | 1984 |
House officer management of the febrile child. A survey.
Topics: Acetaminophen; Aspirin; Brain Damage, Chronic; Fever; Humans; Infant; Seizures; Surveys and Question | 1983 |
Preischemic hyperglycemia leads to delayed postischemic hyperthermia.
Topics: Acetaminophen; Animals; Body Temperature Regulation; Brain Ischemia; Fever; Glucose; Hypercapnia; Hy | 1994 |
Interaction of ciprofloxacin with diclofenac and paracetamol in relation to it's epileptogenic effect.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, N | 1997 |
Phenytoin as a possible cause of acetaminophen hepatotoxicity: case report and review of the literature.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Cytochrome P-450 CYP2E1; Cytochrome P-450 | 2000 |
Antipyretic effect and plasma concentrations of rectal acetaminophen and diazepam in children.
Topics: Acetaminophen; Body Temperature; Child; Child, Preschool; Diazepam; Drug Therapy, Combination; Fever | 1979 |
Prostaglandin E1-induced alterations in visually-evoked response and production of epileptiform activity.
Topics: Acetaminophen; Animals; Bromcresol Green; Electroencephalography; Evoked Potentials; Female; Indomet | 1977 |
[Treatment: fever depressive measures].
Topics: Acetaminophen; Analgesics; Aspirin; Child; Cryotherapy; Humans; Seizures; Seizures, Febrile | 1977 |
Survey of pain management therapy provided for children with sickle cell disease.
Topics: Acetaminophen; Analgesics; Anemia, Sickle Cell; Child; Child, Preschool; Codeine; Drug Administratio | 1992 |
Effect of febrile illness and its treatment on anticonvulsant levels in children.
Topics: Acetaminophen; Anti-Bacterial Agents; Anticonvulsants; Child; Drug Interactions; Fever; Humans; Kine | 1986 |
Differential effect of prostaglandin synthetase inhibitor pretreatment on pentylenetetrazol-induced seizures in rat.
Topics: Acetaminophen; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Electric Stimulation; Electroen | 1985 |
Antipyretics.
Topics: Acetaminophen; Analgesics; Aspirin; Child; Health Education; Humans; Indomethacin; Mefenamic Acid; P | 1972 |
Seizures and fever.
Topics: Acetaminophen; Acidosis, Respiratory; Age Factors; Alkalosis, Respiratory; Aspirin; Brain Diseases; | 1971 |