acetaminophen has been researched along with Abortion, Tubal in 4 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Excerpt | Relevance | Reference |
---|---|---|
" Only one study found evidence of an effect between interventions on pain score: a prophylactic dose of ibuprofen 1600 mg likely reduces the pain score when compared to a dose of paracetamol 2000 mg (mean difference (MD) 2." | 5.22 | Pain management for medical abortion before 14 weeks' gestation. ( Cameron, S; Morroni, C; Reynolds-Wright, JJ; Woldetsadik, MA, 2022) |
"We estimated the proportion of miscarriage to be almost doubled, whereas there was no increased risk of congenital abnormalities or prematurity in women exposed to a drug overdose compared with the background population." | 1.31 | Pregnancy outcome after suicide attempt by drug use: a Danish population-based study. ( Flint, C; Larsen, H; Nielsen, GL; Olsen, J; Sørensen, HT, 2002) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Reynolds-Wright, JJ | 1 |
Woldetsadik, MA | 1 |
Morroni, C | 1 |
Cameron, S | 1 |
Li, DK | 1 |
Liu, L | 1 |
Odouli, R | 1 |
Flint, C | 1 |
Larsen, H | 1 |
Nielsen, GL | 1 |
Olsen, J | 1 |
Sørensen, HT | 1 |
Riggs, BS | 1 |
Bronstein, AC | 1 |
Kulig, K | 1 |
Archer, PG | 1 |
Rumack, BH | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Prophylactic Pregabalin to Decrease Pain During Medical Abortion: a Randomized Controlled Trial[NCT02782169] | Phase 4 | 110 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
PAIN CONTROL IN FIRST TRIMESTER MEDICAL ABORTION: A Randomized Trial[NCT01457521] | Phase 4 | 250 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
The Effect of Prophylactic Ibuprofen Versus Placebo on Pain Relief and Success Rates of Medical Abortion: A Double-blind Randomized Placebo Controlled Study[NCT00997074] | Phase 3 | 61 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680] | 11,976 participants (Actual) | Interventional | 2016-03-23 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
reported on an 11-point numerical rating scale (NRS 0-10) where 0 indicates no pain and 10 indicates the most severe pain (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
Intervention | units on a scale (Mean) |
---|---|
Pregabalin | 5.0 |
Placebo | 5.5 |
summed number of tablets used by each participant over the 72 hour study period (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
Intervention | tablets (Median) |
---|---|
Pregabalin | 1 |
Placebo | 2 |
summed number of tablets used by each participant over the 72 hour study period (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
Intervention | tablets (Median) |
---|---|
Pregabalin | 0 |
Placebo | 0.5 |
A participant was included once if they ever reported a symptom during the 72 hour study period, not reflective of how long the symptom lasted. These were all commonly reported side effects during previous research on medication abortions and commonly reported side effects of pregabalin, so they were not included as adverse events. (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
Intervention | participants (Number) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Nausea | Vomiting | Sleepiness | Dizziness | Headache | Blurred Vision | Diarrhea | Constipation | Dry Mouth | |
Placebo | 42 | 30 | 39 | 26 | 17 | 7 | 29 | 15 | 25 |
Pregabalin | 43 | 28 | 47 | 45 | 28 | 15 | 28 | 6 | 22 |
Participant pain was assessed using an 11-point Visual Analog Scale for Pain. Scores ranged from 0 (no pain) to 10 (worst pain possible) (NCT01457521)
Timeframe: 1-2 weeks
Intervention | units on a scale (Mean) |
---|---|
Prophylactic | 7.1 |
Therapeutic | 7.3 |
- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 189 |
Placebo Arm | 230 |
- Birth weight <2500g (NCT02409680)
Timeframe: At delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 1078 |
Placebo Arm | 1153 |
- Birth weight <1500g (NCT02409680)
Timeframe: At delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 78 |
Placebo Arm | 101 |
- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 303 |
Placebo Arm | 353 |
- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 134 |
Placebo Arm | 152 |
- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 141 |
Placebo Arm | 166 |
- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 42 |
Placebo Arm | 30 |
- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 352 |
Placebo Arm | 325 |
- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 264 |
Placebo Arm | 309 |
The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 668 |
Placebo Arm | 754 |
- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 1506 |
Placebo Arm | 1564 |
- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 214 |
Placebo Arm | 246 |
- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 26 |
Placebo Arm | 25 |
- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 54 |
Placebo Arm | 43 |
- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 9 |
Placebo Arm | 12 |
- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 23 |
Placebo Arm | 30 |
Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 290 |
Placebo Arm | 333 |
Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
Intervention | Participants (Count of Participants) |
---|---|
Intervention Arm | 8 |
Placebo Arm | 21 |
1 review available for acetaminophen and Abortion, Tubal
Article | Year |
---|---|
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
3 other studies available for acetaminophen and Abortion, Tubal
Article | Year |
---|---|
Exposure to non-steroidal anti-inflammatory drugs during pregnancy and risk of miscarriage: population based cohort study.
Topics: Abortion, Spontaneous; Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studi | 2003 |
Pregnancy outcome after suicide attempt by drug use: a Danish population-based study.
Topics: Abortion, Spontaneous; Acetaminophen; Adolescent; Adult; Aspirin; Child; Child, Preschool; Denmark; | 2002 |
Acute acetaminophen overdose during pregnancy.
Topics: Abortion, Spontaneous; Acetaminophen; Acetylcysteine; Acute Disease; Adult; Female; Fetal Death; Hum | 1989 |