Page last updated: 2024-10-22

acetaminophen and Abnormalities, Congenital

acetaminophen has been researched along with Abnormalities, Congenital in 4 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"Compared to acetaminophen, mothers reporting NSAIDs were significantly more likely to have offspring with gastroschisis, hypospadias, cleft palate, cleft lip with cleft palate, cleft lip without cleft palate, anencephaly, spina bifida, hypoplastic left heart syndrome, pulmonary valve stenosis, and tetralogy of Fallot (aOR range, 1."3.85Risk comparison for prenatal use of analgesics and selected birth defects, National Birth Defects Prevention Study 1997-2011. ( Ailes, EC; Anderka, M; Broussard, CS; Feldkamp, ML; Gilboa, SM; Interrante, JD; Lind, JN; Taylor, LG; Trinidad, J; Werler, MM, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Interrante, JD1
Ailes, EC1
Lind, JN1
Anderka, M1
Feldkamp, ML1
Werler, MM1
Taylor, LG1
Trinidad, J1
Gilboa, SM1
Broussard, CS1
Kiernan, E1
Jones, KL1
Kristensen, DM1
Mazaud-Guittot, S1
Gaudriault, P1
Lesné, L1
Serrano, T1
Main, KM1
Jégou, B1
Gandhi, H1
Davies, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Copenhagen Analgesic Study[NCT04369222]600 participants (Anticipated)Observational2020-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for acetaminophen and Abnormalities, Congenital

ArticleYear
Medications that Cause Fetal Anomalies and Possible Prevention Strategies.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Analg

2019
Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects.
    Nature reviews. Endocrinology, 2016, Volume: 12, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Commerce;

2016

Other Studies

2 other studies available for acetaminophen and Abnormalities, Congenital

ArticleYear
Risk comparison for prenatal use of analgesics and selected birth defects, National Birth Defects Prevention Study 1997-2011.
    Annals of epidemiology, 2017, Volume: 27, Issue:10

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics,

2017
Liver transplant and obstetrics.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2004, Volume: 24, Issue:7

    Topics: Acetaminophen; Adult; Congenital Abnormalities; Drug Overdose; Female; Hepatolenticular Degeneration

2004