Page last updated: 2024-10-21

acetaminophen and AIDS-Related Complex

acetaminophen has been researched along with AIDS-Related Complex in 1 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

AIDS-Related Complex: A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.

Research Excerpts

ExcerptRelevanceReference
"Because serum concentrations of zidovudine decrease after the coadministration of acetaminophen, a pharmacokinetic interaction between zidovudine and acetaminophen is unlikely to increase the risk for hematologic toxicity associated with zidovudine."1.28Acetaminophen does not impair clearance of zidovudine. ( Antoniskis, D; Cohen, J; Ko, R; Koda, R; Leedom, J; Nicoloff, J; Sattler, FR; Shields, M, 1991)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sattler, FR1
Ko, R1
Antoniskis, D1
Shields, M1
Cohen, J1
Nicoloff, J1
Leedom, J1
Koda, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Interaction Between Acetaminophen and Zidovudine[NCT00000731]10 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for acetaminophen and AIDS-Related Complex

ArticleYear
Acetaminophen does not impair clearance of zidovudine.
    Annals of internal medicine, 1991, Jun-01, Volume: 114, Issue:11

    Topics: Acetaminophen; Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Analysis of Variance

1991