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acetaldehyde and Substance Withdrawal Syndrome

acetaldehyde has been researched along with Substance Withdrawal Syndrome in 28 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Research Excerpts

ExcerptRelevanceReference
" Progressive toxemia with acetaldehyde (key pathogenetic stage) and volemic changes were followed by homeostasis disorders and gradual decompensation of the natural detoxification system."7.73Progressive toxemia with acetaldehyde in a reactive form of alcohol withdrawal syndrome. ( Nepomnyashchikh, LM; Remennik, AG; Remennik, VI, 2005)
" Progressive toxemia with acetaldehyde (key pathogenetic stage) and volemic changes were followed by homeostasis disorders and gradual decompensation of the natural detoxification system."3.73Progressive toxemia with acetaldehyde in a reactive form of alcohol withdrawal syndrome. ( Nepomnyashchikh, LM; Remennik, AG; Remennik, VI, 2005)
"A hereditary element to alcohol dependence has been suggested by several adoption and twin studies, but the many contradictions between research results emphasise that any genetic contribution is overshadowed by socio-cultural factors."2.37Psychiatric advances in the understanding and treatment of alcohol dependence. ( Madden, JS, 1984)
"Carbon monoxide and dust were detected in the exhalation of heat-not-burn tobacco."1.48[Health Effects Accompanying the Transition from Cigarettes to Heat-not-burn Tobacco: Nicotine Dependence, Nicotine Withdrawal Symptoms, and Changes in Smoking Behaviors]. ( Kawamura, K; Morioka, I; Yamada, K, 2018)
"There were the possibilities that nicotine dependence and nicotine withdrawal symptoms appear after transition and that the number of heat-not-burn tobacco sticks consumed increases."1.48[Health Effects Accompanying the Transition from Cigarettes to Heat-not-burn Tobacco: Nicotine Dependence, Nicotine Withdrawal Symptoms, and Changes in Smoking Behaviors]. ( Kawamura, K; Morioka, I; Yamada, K, 2018)
"Withdrawal seizure prone (WSP) and withdrawal seizure resistant (WRS) mice were genetically selected to express severe or mild handling-induced convulsions (HIC), respectively, after cessation of chronic ethanol (EtOH) vapor inhalation."1.28Acute dependence on depressant drugs is determined by common genes in mice. ( Belknap, JK; Crabbe, JC; Merrill, C, 1991)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199021 (75.00)18.7374
1990's3 (10.71)18.2507
2000's2 (7.14)29.6817
2010's2 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawamura, K1
Yamada, K1
Morioka, I1
Hoffman, AC1
Evans, SE1
Dahchour, A1
Lallemand, F1
Ward, RJ1
De Witte, P1
Remennik, AG1
Nepomnyashchikh, LM1
Remennik, VI1
Churkin, EA1
Gegenava, NO1
Thurman, RG1
Winn, K1
Urquhart, B1
Madden, JS1
Borisenko, SA1
Mannisto, PT1
Burov, IuV1
Phillips, SC1
Cragg, BG1
Iwahashi, K1
Itoh, M1
Nakamura, K1
Ameno, K1
Suwaki, H1
Takeuchi, Y1
Goldstein, DB2
Collins, MA2
Nijm, WP2
Borge, GF2
Teas, G2
Goldfarb, C2
Origitano, T1
Ylikahri, RH1
Leino, T1
Huttunen, MO1
Pösö, AR1
Eriksson, CJ1
Crabbe, JC1
Merrill, C1
Belknap, JK1
Guzmán, M1
Castro, J1
Nordmann, R1
Kuriyama, K1
Ohkuma, S1
Taguchi, J1
Hashimoto, T1
Clow, A1
Topham, A1
Saunders, JB1
Murray, R1
Sandler, M1
Ortiz, A4
Littleton, JM4
Griffiths, PJ4
Myerson, RM1
Magrinat, G1
Dolan, JP1
Biddy, RL1
Miller, LD1
Korol, B1
Mendelson, JH2
Majchrowicz, E1

Reviews

6 reviews available for acetaldehyde and Substance Withdrawal Syndrome

ArticleYear
Abuse potential of non-nicotine tobacco smoke components: acetaldehyde, nornicotine, cotinine, and anabasine.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013, Volume: 15, Issue:3

    Topics: Acetaldehyde; Anabasine; Animals; Cotinine; Dopamine; Humans; Mesencephalon; Nicotine; Smoking; Subs

2013
[Hemosorption in narcologic practice].
    Sovetskaia meditsina, 1984, Issue:12

    Topics: Acetaldehyde; Alcohol Withdrawal Delirium; Anesthesia, General; Blood Proteins; Carbon Dioxide; Cate

1984
Psychiatric advances in the understanding and treatment of alcohol dependence.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1984, Volume: 19, Issue:4

    Topics: Acetaldehyde; Adoption; Alcohol Oxidoreductases; Alcoholic Intoxication; Alcoholism; Antidepressive

1984
Pharmacological aspects of physical dependence on ethanol.
    Life sciences, 1976, Mar-15, Volume: 18, Issue:6

    Topics: Acetaldehyde; Adenosine Triphosphatases; Alcoholism; Animals; Behavior, Animal; Disease Models, Anim

1976
Metabolic aspects of alcohol and their biological significance.
    The Medical clinics of North America, 1973, Volume: 57, Issue:4

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Bone and Bones; Cardiomyopathies; Catala

1973
Biologic concomitants of alcoholism. 1.
    The New England journal of medicine, 1970, Jul-02, Volume: 283, Issue:1

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholic Intoxication; Alcoholism; Animals; Blood Glucose; C

1970

Trials

1 trial available for acetaldehyde and Substance Withdrawal Syndrome

ArticleYear
Effects of fructose and glucose on ethanol-induced metabolic changes and on the intensity of alcohol intoxication and hangover.
    European journal of clinical investigation, 1976, Jan-30, Volume: 6, Issue:1

    Topics: Acetaldehyde; Acidosis; Adult; Blood Glucose; Ethanol; Fatty Acids, Nonesterified; Fructose; Glucose

1976

Other Studies

21 other studies available for acetaldehyde and Substance Withdrawal Syndrome

ArticleYear
[Health Effects Accompanying the Transition from Cigarettes to Heat-not-burn Tobacco: Nicotine Dependence, Nicotine Withdrawal Symptoms, and Changes in Smoking Behaviors].
    Nihon eiseigaku zasshi. Japanese journal of hygiene, 2018, Volume: 73, Issue:3

    Topics: Acetaldehyde; Adult; Ammonia; Breath Tests; Carbon Monoxide; Cotinine; Dust; Formaldehyde; Humans; M

2018
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats.
    European journal of pharmacology, 2005, Sep-27, Volume: 520, Issue:1-3

    Topics: Acamprosate; Acetaldehyde; Alcohol Deterrents; Alcoholism; Animals; Disease Models, Animal; Ethanol;

2005
Progressive toxemia with acetaldehyde in a reactive form of alcohol withdrawal syndrome.
    Bulletin of experimental biology and medicine, 2005, Volume: 139, Issue:6

    Topics: Acetaldehyde; Critical Care; Ethanol; Female; Humans; Hypovolemia; Male; Substance Withdrawal Syndro

2005
Rat brain cyclic AMP levels and withdrawal behavior following treatment with t-butanol.
    Advances in experimental medicine and biology, 1980, Volume: 126

    Topics: Acetaldehyde; Animals; Brain; Butanols; Cyclic AMP; Ethanol; Female; Humans; Rats; Substance Withdra

1980
[Effect of alcohol on serum thyrotropin concentration of rats predisposed and unpredisposed to alcohol].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:7

    Topics: Acetaldehyde; Alcoholism; Animals; Brain; Cold Temperature; Disease Susceptibility; Dopamine; Female

1981
Weakening of the blood-brain barrier by alcohol-related stresses in the rat.
    Journal of the neurological sciences, 1982, Volume: 54, Issue:2

    Topics: Acetaldehyde; Animals; Blood-Brain Barrier; Capillary Permeability; Ethanol; Humans; Male; Rats; Rat

1982
[Acetaldehyde adducts in the cerebral cortex of ethanol-fed mice].
    Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, 1997, Volume: 32, Issue:5

    Topics: Acetaldehyde; Alcoholism; Animals; Brain; Disease Models, Animal; Immunohistochemistry; Male; Mice;

1997
Some promising fields of inquiry in biomedical alcohol research.
    Journal of studies on alcohol. Supplement, 1979, Volume: 8

    Topics: Acetaldehyde; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholism; Animals; Female; Fetal Alcohol

1979
Dopamine-related tetrahydroisoquinolines: significant urinary excretion by alcoholics after alcohol consumption.
    Science (New York, N.Y.), 1979, Dec-07, Volume: 206, Issue:4423

    Topics: Acetaldehyde; Adult; Alcoholism; Dopamine; Humans; Isoquinolines; Male; Middle Aged; Salsoline Alkal

1979
Lack of evidence for sustained blood acetaldehyde concentrations during alcohol detoxification.
    Research communications in chemical pathology and pharmacology, 1978, Volume: 20, Issue:1

    Topics: Acetaldehyde; Adult; Alcoholism; Ethanol; Humans; Male; Middle Aged; Substance Withdrawal Syndrome;

1978
Acute dependence on depressant drugs is determined by common genes in mice.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:2

    Topics: Acetaldehyde; Animals; Butanols; Ethanol; Injections, Intraperitoneal; Male; Mice; Pentobarbital; Se

1991
Alterations in the regulatory properties of hepatic fatty acid oxidation and carnitine palmitoyltransferase I activity after ethanol feeding and withdrawal.
    Alcoholism, clinical and experimental research, 1990, Volume: 14, Issue:3

    Topics: Acetaldehyde; Acyltransferases; Alcoholism; Animals; Carnitine O-Palmitoyltransferase; Ethanol; Fatt

1990
[Biochemical aspects of dependence on alcohol].
    Acta psychiatrica Belgica, 1985, Volume: 85

    Topics: Acetaldehyde; Alcoholism; Animals; Brain; Ethanol; Membrane Fluidity; Membrane Lipids; Membrane Prot

1985
Alcohol, acetaldehyde and salsolinol-induced alterations in function and metabolism of cerebral GABAergic and cholinergic neurons: possible involvements in alcohol dependence and withdrawal.
    Progress in clinical and biological research, 1987, Volume: 241

    Topics: Acetaldehyde; Alcoholism; Animals; Brain; Cells, Cultured; Cerebral Cortex; Ethanol; Isoquinolines;

1987
The role of salsolinol in alcohol intake and withdrawal.
    Progress in clinical and biological research, 1985, Volume: 183

    Topics: Acetaldehyde; Alcoholism; Ethanol; Humans; Isoquinolines; Levodopa; Male; Middle Aged; Substance Wit

1985
Letter: A simple screening test for drugs of potential use in ethanol withdrawal.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:12

    Topics: Acetaldehyde; Animals; Drug Evaluation, Preclinical; Ethanol; Humans; Male; Mice; Seizures; Substanc

1973
The induction of ethanol dependence and the ethanol withdrawal syndrome: the effects of pyrazole.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Body Weight; Brain Chemistry; Disease Mo

1974
A comparison of the effects of chronic administration of ethanol and acetaldehyde to mice: evidence for a role of acetaldehyde in ethanol dependence.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:4

    Topics: Acetaldehyde; Aerosols; Alcoholism; Animals; Behavior, Animal; Brain; Brain Chemistry; Dopamine; Eth

1974
Ethanol and methanol metabolites in alcohol withdrawal.
    Nature, 1973, Jul-27, Volume: 244, Issue:5413

    Topics: Acetaldehyde; Adult; Aged; Alcoholism; Behavior; Chromatography, Gas; Ethanol; Female; Formates; Hum

1973
Proceedings: Chronic administration of acetaldehyde to mice: behavioural and biochemical similarities with chronic ethanol administration.
    British journal of pharmacology, 1974, Volume: 50, Issue:3

    Topics: Acetaldehyde; Animals; Behavior, Animal; Ethanol; Humans; Male; Mice; Substance Withdrawal Syndrome

1974
Blood methanol concentrations during experimentally induced ethanol intoxication in alcoholics.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:2

    Topics: Acetaldehyde; Acetone; Adult; Alcoholic Beverages; Alcoholic Intoxication; Alcoholism; Chromatograph

1971