acetaldehyde has been researched along with Pregnancy in 118 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The development of histaminergic pathways has been studied in the rat brain specially as influenced by maternal alcoholism." | 7.66 | Development of histaminergic pathways in brain as influenced by maternal alcoholism. ( Rawat, AK, 1980) |
| "Separately, using the key words fetal alcohol syndrome, epidemiology, prevalence, incidence, and frequency, articles were identified reporting ARBD incidences among the offspring of heavy drinkers." | 5.31 | The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure. ( Einarson, TR; Hard, ML; Koren, G, 2001) |
| "To compare the usefulness of carbohydrate-deficient transferrin (CDT), the ratio of CDT to total transferrin, and hemoglobin-acetaldehyde adducts with mean cell volume (MCV) and gamma-glutamyl transferase (GGT) in the follow-up of alcohol abuse during pregnancy." | 3.70 | Mean cell volume and gamma-glutamyl transferase are superior to carbohydrate-deficient transferrin and hemoglobin-acetaldehyde adducts in the follow-up of pregnant women with alcohol abuse. ( Eriksson, CJ; Halmesmäki, E; Niemelä, O; Sarkola, T; Sillanaukee, P, 2000) |
| "To explore the mechanism of the retardation and abnormality of nerve system development induced by drinking alcohol during pregnancy, 3H-TdR incorporation was used to study the proliferation of astroglial cells of fetal brain induced by alcohol and its metabolite acetaldehyde in vitro." | 3.70 | [Effects of alcohol and metabolite acetaldehyde on the proliferation of astroglial cells of fetal brain]. ( Qu, W; Wu, D, 1999) |
| "Disulfiram, in 1 mg and 10 mg oral doses, was given to inbred C3H mice prior to and for the duration of pregnancy." | 3.67 | The effects of disulfiram on the experimental C3H mouse embryo. ( Folb, PI; Thompson, PA, 1985) |
| "The development of histaminergic pathways has been studied in the rat brain specially as influenced by maternal alcoholism." | 3.66 | Development of histaminergic pathways in brain as influenced by maternal alcoholism. ( Rawat, AK, 1980) |
| "Acute alcohol abuse causes damage to and functional impairment of several organs affecting protein, carbohydrate, and fat metabolism." | 2.46 | Cellular and mitochondrial effects of alcohol consumption. ( Manzo-Avalos, S; Saavedra-Molina, A, 2010) |
| "Alcohol dependence is correlated with a wide spectrum of medical, psychological, behavioral, and social problems." | 2.46 | Cellular and mitochondrial effects of alcohol consumption. ( Manzo-Avalos, S; Saavedra-Molina, A, 2010) |
| "A hereditary element to alcohol dependence has been suggested by several adoption and twin studies, but the many contradictions between research results emphasise that any genetic contribution is overshadowed by socio-cultural factors." | 2.37 | Psychiatric advances in the understanding and treatment of alcohol dependence. ( Madden, JS, 1984) |
| "The biochemical basis of fetal alcohol syndrome is low hepatic alcohol dehydrogenase (EC 1." | 2.36 | Effect of alcohol on the heart and cardiac metabolism. ( Bing, RJ, 1982) |
| "Fanconi anemia is characterized by a higher sensitivity to DNA crosslinking agents, including aldehydes." | 1.40 | The maternal side of Fanconi Anemia. ( Fernandez-Capetillo, O; Ruiz, S, 2014) |
| "Separately, using the key words fetal alcohol syndrome, epidemiology, prevalence, incidence, and frequency, articles were identified reporting ARBD incidences among the offspring of heavy drinkers." | 1.31 | The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure. ( Einarson, TR; Hard, ML; Koren, G, 2001) |
| "The adverse effects of maternal alcohol consumption on the development of the fetus are well known." | 1.29 | Protective effect of Liv.52 on alcohol-induced fetotoxicity. ( Chauhan, BL; Gopumadhavan, S; Jagadeesh, S; Kulkarni, RD, 1993) |
| "Acetaldehyde was found in maternal blood, fetal blood, and amniotic fluid at concentrations at least 1000-fold lower than the ethanol concentrations, and was variable." | 1.28 | Ethanol and acetaldehyde concentrations in pregnant rats after administration of ethanol. ( Hayashi, M, 1991) |
| "Acetaldehyde was measurable in maternal blood and fetal body at similar concentrations, which were 100- to 1000-fold less than the respective ethanol concentrations." | 1.28 | Ontogeny of the activity of alcohol dehydrogenase and aldehyde dehydrogenases in the liver and placenta of the guinea pig. ( Brien, JF; Card, SE; Tompkins, SF, 1989) |
| "The results suggest that in chronic alcohol abuse, the placenta plays a negligible role in the metabolism of ethanol and acetaldehyde." | 1.28 | Placental alcohol metabolism in chronic alcohol abuse. ( Andersson, S; Halmesmäki, E; Koivusalo, M; Lapatto, R; Ylikorkala, O, 1989) |
| "The proximate teratogen of the fetal alcohol syndrome is unknown." | 1.27 | Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde. ( Blakley, PM; Scott, WJ, 1984) |
| "Acetaldehyde was detectable in maternal blood following all treatments and in maternal liver and embryos following treatment with 7 g/kg ethanol." | 1.27 | Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 2. Pharmacokinetics of the placental transfer of ethanol and acetaldehyde. ( Blakley, PM; Scott, WJ, 1984) |
| "Acetaldehyde was present in the maternal venous blood of four subjects, and the maximum acetaldehyde concentration occurred at about the same time as the maximum maternal venous blood ethanol concentration." | 1.27 | Disposition of ethanol in human maternal venous blood and amniotic fluid. ( Brien, JF; Loomis, CW; McGrath, M; Tranmer, J, 1983) |
| " There was delayed transfer of ethanol into the amniotic and allantoic fluids during the dosing period, followed by higher ethanol concentrations in these fluids during the elimination phase compared with fetal blood." | 1.27 | Disposition of acute, multiple-dose ethanol in the near-term pregnant ewe. ( Brien, JF; Clarke, DW; Patrick, J; Richardson, B; Smith, GN, 1987) |
| "Acetaldehyde was measurable in all the biological fluids and tissues at concentrations that were at least 1,000-fold less than the respective ethanol concentrations and were variable." | 1.27 | Pharmacokinetics of ethanol and its metabolite, acetaldehyde, and fetolethality in the third-trimester pregnant guinea pig for oral administration of acute, multiple-dose ethanol. ( Brien, JF; Clarke, DW; Slack, CJ; Steenaart, NA, 1986) |
| " The data indicate that, for administration of this ethanol dosage regimen to the third-trimester pregnant ewe, there is rapid, bidirectional placental transfer of ethanol; elimination of ethanol from the fetus is regulated primarily by maternal elimination of ethanol; the amniotic fluid may serve as a reservoir for ethanol in utero; and there is appreciable acetaldehyde-metabolizing capacity." | 1.27 | Disposition of ethanol in maternal blood, fetal blood, and amniotic fluid of third-trimester pregnant ewes. ( Brien, JF; Clarke, DW; Patrick, J; Richardson, B, 1985) |
| "Acetaldehyde-treated females had more resorptions both at mid-gestation and at term, though no significant difference in maternal weight gain was observed." | 1.26 | The teratogenic effect of acetaldehyde: implications for the study of the fetal alcohol syndrome. ( Kaufman, MH; O'Shea, KS, 1979) |
| "The symptoms of the fetal alcohol syndrome and their frequency of appearance are described based on 41 reports in the literature and on own observations." | 1.26 | The fetal alcohol syndrome: symptoms and pathogenesis. ( Igali, S; Imrei, J; Kardos, G; Leisztner, L; Osztovics, M; Szaszovszky, E; Véghelyi, PV, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 78 (66.10) | 18.7374 |
| 1990's | 19 (16.10) | 18.2507 |
| 2000's | 11 (9.32) | 29.6817 |
| 2010's | 10 (8.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Correia-Branco, A | 1 |
| Keating, E | 1 |
| Martel, F | 1 |
| Wang, C | 1 |
| Turunen, SP | 1 |
| Kummu, O | 1 |
| Veneskoski, M | 1 |
| Lehtimäki, J | 1 |
| Nissinen, AE | 1 |
| Hörkkö, S | 1 |
| Lui, S | 1 |
| Jones, RL | 1 |
| Robinson, NJ | 1 |
| Greenwood, SL | 1 |
| Aplin, JD | 1 |
| Tower, CL | 1 |
| Oberbeck, N | 1 |
| Langevin, F | 2 |
| King, G | 1 |
| de Wind, N | 1 |
| Crossan, GP | 2 |
| Patel, KJ | 2 |
| Delan-Forino, C | 1 |
| Tollervey, D | 1 |
| Ruiz, S | 1 |
| Fernandez-Capetillo, O | 1 |
| Manzo-Avalos, S | 1 |
| Saavedra-Molina, A | 1 |
| Joenje, H | 1 |
| Rosado, IV | 1 |
| Arends, MJ | 1 |
| Joya, X | 1 |
| Friguls, B | 1 |
| Ortigosa, S | 1 |
| Papaseit, E | 1 |
| Martínez, SE | 1 |
| Manich, A | 1 |
| Garcia-Algar, O | 1 |
| Pacifici, R | 1 |
| Vall, O | 1 |
| Pichini, S | 1 |
| Cook, JD | 1 |
| KAPELLER-ADLER, R | 1 |
| Nava-Ocampo, AA | 1 |
| Velázquez-Armenta, Y | 1 |
| Brien, JF | 7 |
| Koren, G | 2 |
| Lee, RD | 1 |
| An, SM | 1 |
| Kim, SS | 1 |
| Rhee, GS | 1 |
| Kwack, SJ | 1 |
| Seok, JH | 1 |
| Chae, SY | 1 |
| Park, CH | 1 |
| Choi, YW | 1 |
| Kim, HS | 1 |
| Cho, HY | 1 |
| Lee, BM | 1 |
| Park, KL | 1 |
| Kido, R | 1 |
| Sato, I | 1 |
| Tsuda, S | 1 |
| Park, MK | 1 |
| Belluzzi, JD | 1 |
| Han, SH | 1 |
| Cao, J | 1 |
| Leslie, FM | 1 |
| Kovacic, P | 1 |
| Espinet, C | 1 |
| Argilés, JM | 1 |
| Véghelyi, PV | 5 |
| Ryle, PR | 1 |
| Thomson, AD | 1 |
| Bing, RJ | 1 |
| Marks, V | 1 |
| Blakley, PM | 2 |
| Scott, WJ | 2 |
| Beck, F | 1 |
| Huxham, IM | 1 |
| Gulamhusein, AP | 1 |
| Madden, JS | 1 |
| Fisher, SE | 4 |
| Atkinson, M | 3 |
| Van Thiel, DH | 4 |
| Sreenathan, RN | 4 |
| Singh, S | 4 |
| Padmanabhan, R | 4 |
| Guerri, C | 3 |
| Esquifino, A | 1 |
| Sanchis, R | 2 |
| Grisolía, S | 1 |
| Henderson, GI | 5 |
| Patwardhan, RV | 2 |
| McLeroy, S | 1 |
| Schenker, S | 4 |
| Loomis, CW | 1 |
| Tranmer, J | 1 |
| McGrath, M | 1 |
| Campbell, MA | 1 |
| Fantel, AG | 1 |
| Webster, WS | 1 |
| Walsh, DA | 1 |
| McEwen, SE | 1 |
| Lipson, AH | 1 |
| Mukherjee, AB | 1 |
| Hodgen, GD | 1 |
| Skakun, NP | 1 |
| Dreosti, IE | 1 |
| Ballard, FJ | 1 |
| Belling, GB | 1 |
| Record, IR | 1 |
| Manuel, SJ | 1 |
| Hetzel, BS | 1 |
| Gavaler, JS | 1 |
| Eagon, PK | 1 |
| Cobb, CF | 1 |
| Chiao, YB | 1 |
| Lester, R | 1 |
| Bannigan, J | 1 |
| Burke, P | 1 |
| Thompson, PA | 2 |
| Folb, PI | 2 |
| Rawat, AK | 2 |
| Majewski, F | 1 |
| Nesterick, CA | 1 |
| Rahwan, RG | 1 |
| Skosyreva, AM | 1 |
| Turner, D | 1 |
| Lumeng, L | 1 |
| Hoyumpa, AM | 1 |
| Leistner, L | 1 |
| Rosenblum, E | 1 |
| David, R | 2 |
| Holzman, I | 2 |
| Popov, VB | 1 |
| Vaisman, BL | 1 |
| Puchkov, VF | 1 |
| Ignat'eva, TV | 1 |
| Véghelyi, P | 1 |
| Leisztner, L | 2 |
| Osztovics, M | 4 |
| Korányi, G | 1 |
| Kardos, G | 2 |
| Ullrich, E | 1 |
| Cooper, P | 1 |
| Reddy, BV | 2 |
| Boyadjieva, N | 1 |
| Sarkar, DK | 2 |
| Hassoun, EA | 1 |
| Bagchi, D | 1 |
| Stohs, SJ | 1 |
| Gopumadhavan, S | 1 |
| Jagadeesh, S | 1 |
| Chauhan, BL | 1 |
| Kulkarni, RD | 1 |
| Guizzetti, M | 1 |
| Costa, LG | 1 |
| Stone, WS | 1 |
| Altman, HJ | 1 |
| Hall, J | 1 |
| Arankowsky-Sandoval, G | 1 |
| Parekh, P | 1 |
| Gold, PE | 1 |
| Hamby-Mason, R | 1 |
| Chen, JJ | 1 |
| Perez, A | 1 |
| Ma, X | 1 |
| Svegliati-Baroni, G | 1 |
| Poniachik, J | 1 |
| Baraona, E | 1 |
| Lieber, CS | 2 |
| Johnson, PD | 1 |
| Dawson, BV | 1 |
| Goldberg, SJ | 1 |
| Stoler, JM | 1 |
| Huntington, KS | 1 |
| Peterson, CM | 1 |
| Peterson, KP | 1 |
| Daniel, P | 1 |
| Aboagye, KK | 1 |
| Lieberman, E | 1 |
| Ryan, L | 1 |
| Holmes, LB | 1 |
| Khalighi, M | 1 |
| Brzezinski, MR | 1 |
| Chen, H | 1 |
| Juchau, MR | 1 |
| Sarkola, T | 1 |
| Eriksson, CJ | 1 |
| Niemelä, O | 2 |
| Sillanaukee, P | 1 |
| Halmesmäki, E | 3 |
| Menegola, E | 1 |
| Broccia, ML | 1 |
| Di Renzo, F | 1 |
| Giavini, E | 1 |
| Hard, ML | 1 |
| Einarson, TR | 1 |
| Klug, S | 1 |
| Merker, HJ | 1 |
| Jäckh, R | 1 |
| Qu, W | 2 |
| Xiao, B | 1 |
| Wu, D | 2 |
| Obe, G | 1 |
| Ristow, H | 1 |
| Goldstein, DB | 1 |
| O'Shea, KS | 1 |
| Kaufman, MH | 1 |
| Taskaev, II | 1 |
| Kouri, M | 1 |
| Koivula, T | 1 |
| Koivusalo, M | 2 |
| Sjöblom, M | 1 |
| Pilström, L | 1 |
| Mørland, J | 1 |
| Szaszovsky, E | 1 |
| Szaszovszky, E | 1 |
| Igali, S | 1 |
| Imrei, J | 1 |
| Kesäniemi, YA | 4 |
| Sippel, HW | 2 |
| Imai, T | 1 |
| Omoto, M | 1 |
| Ylikorkala, O | 2 |
| Hayashi, M | 2 |
| Shimazaki, Y | 1 |
| Kamata, S | 1 |
| Kakiichi, N | 1 |
| Ikeda, M | 1 |
| Randall, CL | 2 |
| Ekblad, U | 1 |
| Anton, RF | 1 |
| Becker, HC | 1 |
| Phillips, DK | 1 |
| Baskin, GS | 1 |
| Vilaró, S | 1 |
| Viñas, O | 1 |
| Remesar, X | 1 |
| Zorzano, A | 2 |
| Herrera, E | 2 |
| Clarke, DW | 4 |
| Smith, GN | 2 |
| Patrick, J | 3 |
| Richardson, B | 3 |
| Kalmus, GW | 1 |
| Buckenmaier, CC | 1 |
| Card, SE | 1 |
| Tompkins, SF | 1 |
| Andersson, S | 1 |
| Lapatto, R | 1 |
| Karl, PI | 1 |
| Gordon, BH | 1 |
| Khokha, AM | 1 |
| Ali, F | 1 |
| Persaud, TV | 1 |
| Slegel, P | 1 |
| Kitagawa, H | 1 |
| Maguire, MH | 1 |
| Custo, GM | 1 |
| Mastrofini, P | 1 |
| Corazzi, L | 1 |
| Arienti, G | 1 |
| Steenaart, NA | 1 |
| Slack, CJ | 1 |
| Suwaki, H | 1 |
| Priscott, PK | 2 |
| Ford, JR | 1 |
| Meier-Tackmann, D | 1 |
| Korenke, GC | 1 |
| Agarwal, DP | 1 |
| Goedde, HW | 1 |
| Asai, M | 1 |
| Narita, O | 1 |
| Kashiwamata, S | 1 |
| Smith, M | 1 |
| Hopkinson, DA | 1 |
| Harris, H | 1 |
| Nichols, WK | 1 |
| Dixon, RL | 1 |
15 reviews available for acetaldehyde and Pregnancy
| Article | Year |
|---|---|
Cellular and mitochondrial effects of alcohol consumption.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Ethanol; Female; Fetal Alcohol Spec | 2010 |
Determination of maternal-fetal biomarkers of prenatal exposure to ethanol: a review.
Topics: Acetaldehyde; Alanine Transaminase; Alcohol Drinking; Aspartate Aminotransferases; Biomarkers; Eryth | 2012 |
Biochemical markers of alcohol use in pregnant women.
Topics: Acetaldehyde; Alcohol Drinking; Alcohols; Biomarkers; Erythrocyte Indices; Female; Fetal Alcohol Spe | 2003 |
Protein electron transfer (mechanism and reproductive toxicity): iminium, hydrogen bonding, homoconjugation, amino acid side chains (redox and charged), and cell signaling.
Topics: Acetaldehyde; Amino Acids; Animals; Electron Transport; Ethanol; Female; Humans; Hydrogen Bonding; I | 2007 |
Effect of alcohol on the heart and cardiac metabolism.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Calcium; Cell Membrane; Dogs; | 1982 |
Clinical pathology of alcohol.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Child; Cushing Syndrome; Endocrine Glands; Enzyme | 1983 |
Psychiatric advances in the understanding and treatment of alcohol dependence.
Topics: Acetaldehyde; Adoption; Alcohol Oxidoreductases; Alcoholic Intoxication; Alcoholism; Antidepressive | 1984 |
[Kinetics and teratogenic action of ethyl alcohol].
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Alcohol Oxidoreductases; Animals; Biotransformatio | 1981 |
Adverse effects of ethanol upon sexual functioning: experimental studies in animals.
Topics: Acetaldehyde; Alcoholism; Animals; Dogs; Ethanol; Female; Gonadal Steroid Hormones; Humans; Male; Mi | 1981 |
Teratogenic effects of alcohol: current status of animal research and in vitro models.
Topics: Acetaldehyde; Animals; Central Nervous System; Disease Models, Animal; Embryonic and Fetal Developme | 1996 |
Mutagenic, cancerogenic and teratogenic effects of alcohol.
Topics: Acetaldehyde; Adult; Alcoholism; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; Drosophi | 1979 |
Perspectives on the pathophysiology of fetal alcohol syndrome.
Topics: Acetaldehyde; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetal Growth Retardation; | 1990 |
Fetal alcohol syndrome: current status of pathogenesis.
Topics: Acetaldehyde; Animals; Dose-Response Relationship, Drug; Ethanol; Female; Fetal Alcohol Spectrum Dis | 1990 |
[Pathogenesis of the fetal alcohol syndrome].
Topics: Acetaldehyde; Alcoholism; Female; Fetal Alcohol Spectrum Disorders; Humans; Placenta; Pregnancy; Pre | 1988 |
Alcohol and alcohol problems research 2. Japan.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Female; Fetal Alcohol Spectrum D | 1985 |
103 other studies available for acetaldehyde and Pregnancy
| Article | Year |
|---|---|
Involvement of mTOR, JNK and PI3K in the negative effect of ethanol and metformin on the human first-trimester extravillous trophoblast HTR-8/SVneo cell line.
Topics: Acetaldehyde; Apoptosis; Cell Line; Cell Movement; Cell Survival; Ethanol; Female; Humans; Hypoglyce | 2018 |
Natural antibodies of newborns recognize oxidative stress-related malondialdehyde acetaldehyde adducts on apoptotic cells and atherosclerotic plaques.
Topics: Acetaldehyde; Apoptosis; Female; Fetal Blood; Humans; Immunoglobulin Fab Fragments; Immunoglobulin M | 2013 |
Detrimental effects of ethanol and its metabolite acetaldehyde, on first trimester human placental cell turnover and function.
Topics: Acetaldehyde; Amino Acids; Apoptosis; Biological Transport; Cell Proliferation; Ethanol; Female; Hum | 2014 |
Maternal aldehyde elimination during pregnancy preserves the fetal genome.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitoc | 2014 |
Lighting Up pre-mRNA recognition.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Embryo, Mammalian; Ethanol; Fanconi Anemia; Fanconi A | 2014 |
The maternal side of Fanconi Anemia.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Embryo, Mammal | 2014 |
Metabolism: alcohol, DNA and disease.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Anima | 2011 |
Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Alleles; Ani | 2011 |
The isolation of iminazole acetaldehyde as the only metabolite of the action in vitro of placental histaminase on histamine.
Topics: Acetaldehyde; Amine Oxidase (Copper-Containing); Animals; Female; Histamine; Imidazoles; In Vitro Te | 1960 |
Elimination kinetics of ethanol in pregnant women.
Topics: Acetaldehyde; Adult; Algorithms; Amniotic Fluid; Area Under Curve; Central Nervous System Depressant | 2004 |
Neurotoxic effects of alcohol and acetaldehyde during embryonic development.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaldehyde; Animals; Antioxidants; Catalase; Cells, Cultured; Deoxygu | 2005 |
Detection of in vivo DNA damage induced by ethanol in multiple organs of pregnant mice using the alkaline single cell gel electrophoresis (Comet) assay.
Topics: Acetaldehyde; Analysis of Variance; Animals; Comet Assay; Disulfiram; DNA Damage; Dose-Response Rela | 2006 |
Age, sex and early environment contribute to individual differences in nicotine/acetaldehyde-induced behavioral and endocrine responses in rats.
Topics: Acetaldehyde; Aging; Animals; Animals, Newborn; Behavior, Animal; Catheterization, Peripheral; Corti | 2007 |
Ethanol and acetaldehyde concentrations in the rat foeto-maternal system after an acute ethanol administration given to the mother.
Topics: Acetaldehyde; Animals; Ethanol; Female; Maternal-Fetal Exchange; Metabolic Clearance Rate; Pregnancy | 1984 |
Fetal abnormality and maternal ethanol metabolism.
Topics: Acetaldehyde; Alcoholism; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Maternal-Fetal | 1983 |
Acetaldehyde and the fetal alcohol syndrome.
Topics: Acetaldehyde; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Infant, Newborn; Maternal-F | 1983 |
Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; | 1984 |
Growth of rat embryos in the serum of alcohol drinkers.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Alcohol Drinking; Animals; Blood; Ethanol; Female; | 1984 |
Selective fetal malnutrition: the effect of nicotine, ethanol, and acetaldehyde upon in vitro uptake of alpha-aminoisobutyric acid by human term placental villous slices.
Topics: Acetaldehyde; Alcoholism; Aminoisobutyric Acids; Biological Transport, Active; Chorionic Villi; Etha | 1984 |
Effect of acetaldehyde on skeletogenesis in rats.
Topics: Acetaldehyde; Animals; Bone and Bones; Bone Development; Female; Fetal Alcohol Spectrum Disorders; G | 1984 |
Structural changes of placenta following maternal administration of acetaldehyde in rat.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Female; Placenta; Pregnancy; Rats; Rats, Inbred | 1984 |
Growth, enzymes and hormonal changes in offspring of alcohol-fed rats.
Topics: Acetaldehyde; Animals; Cell Membrane; Enzymes; Ethanol; Female; Growth; Luteinizing Hormone; Neurons | 1984 |
Gyromitrin (acetaldehyde formylmethylhydrazone).
Topics: Acetaldehyde; Animals; Carcinogens; Chemical Phenomena; Chemistry; Female; Humans; Lethal Dose 50; M | 1983 |
Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 2. Pharmacokinetics of the placental transfer of ethanol and acetaldehyde.
Topics: Acetaldehyde; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetal Blood; Fomepizole; K | 1984 |
Implication of the placenta in acetaldehyde-induced intrauterine growth retardation.
Topics: Acetaldehyde; Animals; Dose-Response Relationship, Drug; Female; Fetal Growth Retardation; Fetus; Ma | 1984 |
Inhibition of placental amino acid uptake in rats following acute and chronic ethanol exposure.
Topics: Acetaldehyde; Alanine; Alcoholism; Amino Acids; Aminoisobutyric Acids; Animals; Betaine; Cycloleucin | 1982 |
Disposition of ethanol in human maternal venous blood and amniotic fluid.
Topics: Acetaldehyde; Amniotic Fluid; Ethanol; Female; Humans; Maternal-Fetal Exchange; Metabolic Clearance | 1983 |
Teratogenicity of acetaldehyde in vitro: relevance to the fetal alcohol syndrome.
Topics: Acetaldehyde; Animals; Dose-Response Relationship, Drug; Ethanol; Female; Fetal Alcohol Spectrum Dis | 1983 |
Some teratogenic properties of ethanol and acetaldehyde in C57BL/6J mice: implications for the study of the fetal alcohol syndrome.
Topics: Acetaldehyde; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Mice; Mice, Inbred C57BL; | 1983 |
Maternal ethanol exposure induces transient impairment of umbilical circulation and fetal hypoxia in monkeys.
Topics: Acetaldehyde; Animals; Disease Models, Animal; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fe | 1982 |
The effect of ethanol and acetaldehyde on DNA synthesis in growing cells and on fetal development in the rat.
Topics: Acetaldehyde; Animals; Cells, Cultured; DNA; Embryo, Mammalian; Ethanol; Female; Fetus; Liver Regene | 1981 |
Maternal ethanol consumption and fetal development: two potential mechanisms.
Topics: Acetaldehyde; Alcohol Drinking; Amino Acids; Animals; Body Temperature; Female; Fetus; Hypothermia; | 1982 |
Teratogenic effects of acetaldehyde in the rat.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Bone and Bones; Dose-Response Relationship, Drug | 1982 |
Ethanol teratogenicity in mice: a light microscopic study.
Topics: Acetaldehyde; Animals; Brain; Embryo, Mammalian; Ethanol; Female; Mesencephalon; Mice; Pregnancy; Te | 1982 |
An in vitro model of alcohol and acetaldehyde teratogenicity.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Brain; DNA; Embryo, Mammalian; Ethanol; Female; | 1982 |
Development of histaminergic pathways in brain as influenced by maternal alcoholism.
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Brain Chemistry; Female; Histamine; Histidine Decarboxylas | 1980 |
Alcohol embryopathy: some facts and speculations about pathogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcoholic Beverages; Alcoholism; Brain; Child; Child, Pre | 1981 |
Absence of a role for salsolinol in the mechanism of ethanol teratogenicity.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcoholism; Animals; Animals, Newborn; Ethanol; Female; F | 1981 |
[Comparative study of the direct embryotoxic effect of alcohol and its metabolite acetaldehyde during organogenesis].
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Dose-Response Relationship, Drug; Embryo, Mammal | 1982 |
Inhibition of placental valine uptake after acute and chronic maternal ethanol consumption.
Topics: Acetaldehyde; Alcohol Drinking; Amino Acids; Animals; Ethanol; Female; In Vitro Techniques; Placenta | 1981 |
[Fetal alcohol syndrome].
Topics: Acetaldehyde; Adult; Alcoholism; Chromatography, Gas; Ethanol; Female; Fetal Alcohol Spectrum Disord | 1981 |
Selective fetal malnutrition: the effect of ethanol and acetaldehyde upon in vitro uptake of alpha amino isobutyric acid by human placenta.
Topics: Acetaldehyde; Aminoisobutyric Acids; Biological Transport, Active; Dose-Response Relationship, Drug; | 1981 |
Effect of ethanol upon placental uptake of amino acids.
Topics: Acetaldehyde; Amino Acids; Aminoisobutyric Acids; Animals; Arteries; Ethanol; Female; Humans; Oxygen | 1981 |
[Embryotoxic effect of ethanol and its biotransformation products in cultures of postimplantation rat embryos].
Topics: Acetaldehyde; Animals; Biotransformation; Culture Techniques; Embryonic Development; Ethanol; Female | 1981 |
[Development of the fetal alcohol syndrome].
Topics: Acetaldehyde; Alcoholism; Disulfiram; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Inf | 1980 |
Alcohol and pregnancy--part 1: animal data.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcohol Drinking; Animals; Brain; Ethanol; Female; Fetal | 1980 |
Effect of ethanol, propanol, butanol, and catalase enzyme blockers on beta-endorphin secretion from primary cultures of hypothalamic neurons: evidence for a mediatory role of acetaldehyde in ethanol stimulation of beta-endorphin release.
Topics: 1-Butanol; 1-Propanol; Acetaldehyde; Amitrole; Animals; Azides; beta-Endorphin; Butanols; Catalase; | 1995 |
Evidence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced tissue damage in fetal and placental tissues and changes in amniotic fluid lipid metabolites of pregnant CF1 mice.
Topics: Acetaldehyde; Acetone; Amniotic Fluid; Animals; DNA Damage; Embryonic and Fetal Development; Female; | 1995 |
Effect of alcohol, acetaldehyde, and salsolinol on beta-endorphin secretion from the hypothalamic neurons in primary cultures.
Topics: Acetaldehyde; Animals; beta-Endorphin; Cell Survival; Cells, Cultured; Dopamine; Dose-Response Relat | 1993 |
Protective effect of Liv.52 on alcohol-induced fetotoxicity.
Topics: Acetaldehyde; Amniotic Fluid; Animals; Body Weight; Drug Combinations; Ethanol; Female; Fetal Alcoho | 1993 |
Inhibition of muscarinic receptor-stimulated glial cell proliferation by ethanol.
Topics: Acetaldehyde; Acetylcholine; Animals; Astrocytes; Astrocytoma; Bisbenzimidazole; Bromodeoxyuridine; | 1996 |
Prenatal exposure to alcohol in adult rats: relationships between sleep and memory deficits, and effects of glucose administration on memory.
Topics: Acetaldehyde; Animals; Female; Glucose; Male; Memory; Pregnancy; Prenatal Exposure Delayed Effects; | 1996 |
Catalase mediates acetaldehyde formation from ethanol in fetal and neonatal rat brain.
Topics: Acetaldehyde; Animals; Brain; Catalase; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Gestation | 1997 |
Collagen synthesis by liver stellate cells is released from its normal feedback regulation by acetaldehyde-induced modification of the carboxyl-terminal propeptide of procollagen.
Topics: Acetaldehyde; Animals; Animals, Newborn; Cells, Cultured; Collagen; Ethanol; Feedback; Female; Liver | 1997 |
Cardiac teratogenicity of trichloroethylene metabolites.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Acetates; Animals; Chloral Hydrate; Cystine; Dichloroethy | 1998 |
The prenatal detection of significant alcohol exposure with maternal blood markers.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Biomarkers; Birth Weight; Body Height; Erythrocyte Indices; E | 1998 |
Inhibition of human prenatal biosynthesis of all-trans-retinoic acid by ethanol, ethanol metabolites, and products of lipid peroxidation reactions: a possible role for CYP2E1.
Topics: Acetaldehyde; Adult; Alcohols; Biotransformation; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytosol; E | 1999 |
Mean cell volume and gamma-glutamyl transferase are superior to carbohydrate-deficient transferrin and hemoglobin-acetaldehyde adducts in the follow-up of pregnant women with alcohol abuse.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcohol-Related Disorders; Area Under Curve; Erythrocyte Indi | 2000 |
Acetaldehyde in vitro exposure and apoptosis: a possible mechanism of teratogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Apoptosis; Branchial Region; Cell Death; Embryo, | 2001 |
The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure.
Topics: Acetaldehyde; Alcoholism; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Incidence; Infa | 2001 |
Effects of ethylene glycol and metabolites on in vitro development of rat embryos during organogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animal Testing Alternatives; Animals; Dose-Response Relat | 2001 |
[The effect of alcohol on c-fos gene expression in rat embryo neuroglial].
Topics: Acetaldehyde; Animals; Astrocytes; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethanol; Fem | 2001 |
[Effects of alcohol and metabolite acetaldehyde on the proliferation of astroglial cells of fetal brain].
Topics: Acetaldehyde; Animals; Astrocytes; Brain; Cell Division; Cells, Cultured; Ethanol; Female; Fetus; Pr | 1999 |
Developmental changes in the brain levels of neurotransmitters as influenced by maternal ethanol consumption in the rat.
Topics: 4-Aminobutyrate Transaminase; Acetaldehyde; Acetylcholine; Alcoholism; Animals; Animals, Newborn; Br | 1977 |
Fetal-alcohol syndrome in child whose parents had stopped drinking.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; | 1979 |
Some promising fields of inquiry in biomedical alcohol research.
Topics: Acetaldehyde; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholism; Animals; Female; Fetal Alcohol | 1979 |
The teratogenic effect of acetaldehyde: implications for the study of the fetal alcohol syndrome.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Body Weight; Central Nervous System; Dose-Respon | 1979 |
[Histochemical and cytologic changes in the liver in experimental poisoning and subsequent pregnancy].
Topics: Acetaldehyde; Animals; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Chronic Disease; Fem | 1979 |
Aldehyde dehydrogenase activity in human placenta.
Topics: Acetaldehyde; Aldehyde Oxidoreductases; Animals; Ethanol; Female; Humans; Maternal-Fetal Exchange; M | 1977 |
Activity of alcohol dehydrogenase and acetaldehyde dehydrogenases in the liver and placenta during the development of the rat.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Female; Gestational Age; L | 1978 |
Maternal alcohol consumption and birth weight.
Topics: Acetaldehyde; Alcohol Drinking; Birth Weight; Female; Fetal Alcohol Spectrum Disorders; Humans; Preg | 1978 |
The fetal alcohol syndrome: symptoms and pathogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Aldehyde Oxidoreductases; Animals; Child, Preschoo | 1978 |
Placental and foetal metabolism of acetaldehyde in rat. I. Contents of ethanol and acetaldehyde in placenta and foets of the pregnant rat during ethanol oxidation.
Topics: Acetaldehyde; Animals; Ethanol; Female; Fetus; Maternal-Fetal Exchange; Oxidation-Reduction; Placent | 1975 |
Placental and foetal metabolism of acetaldehyde in rat. II. Studies on metabolism of acetaldehyde in the isolated placenta and foetus.
Topics: Acetaldehyde; Animals; Female; Fetus; Liver; Maternal-Fetal Exchange; Oxidation-Reduction; Placenta; | 1975 |
[Effects of acetaldehyde exposure on maternal rats and their offspring].
Topics: Acetaldehyde; Animals; Body Weight; Brain; Female; Fetal Alcohol Spectrum Disorders; Fetal Organ Mat | 1992 |
Hemoglobin-acetaldehyde adducts are elevated in women carrying alcohol-damaged fetuses.
Topics: Acetaldehyde; Alcohol Drinking; Birth Weight; Dose-Response Relationship, Drug; Female; Fetal Alcoho | 1991 |
Ethanol and acetaldehyde concentrations in pregnant rats after administration of ethanol.
Topics: Acetaldehyde; Animals; Ethanol; Female; Maternal-Fetal Exchange; Pregnancy; Pregnancy, Animal; Rats; | 1991 |
Disposition of ethanol and acetaldehyde in maternal blood, fetal blood, and amniotic fluid of near-term pregnant rats.
Topics: Acetaldehyde; Amniotic Fluid; Animals; Ethanol; Female; Fetus; Liver; Maternal-Fetal Exchange; Pregn | 1991 |
Acetaldehyde.
Topics: Acetaldehyde; Acetates; Acetic Acid; Air Pollutants; Animals; Cannabis; Carcinogens; Chemical Phenom | 1985 |
Altered ultrastructure of lactating rat mammary epithelial cells induced by chronic ethanol ingestion.
Topics: Acetaldehyde; Alcoholism; Animals; Epithelium; Ethanol; Female; Lactation; Mammary Glands, Animal; M | 1989 |
Decreased in vivo rate of ethanol metabolism in the suckLing rat.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Animals, Suckling; Ethanol; Fe | 1989 |
Activity of alcohol dehydrogenase and aldehyde dehydrogenase in maternal liver, fetal liver and placenta of the near-term pregnant ewe.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Ethanol; Female; Fetus; Liver; | 1989 |
Effects of ethanol and acetaldehyde on cultured pre-implantation mouse embryos.
Topics: Acetaldehyde; Animals; Blastocyst; Cell Survival; Embryonic Development; Ethanol; Female; Mice; Moru | 1989 |
Ontogeny of the activity of alcohol dehydrogenase and aldehyde dehydrogenases in the liver and placenta of the guinea pig.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Ethanol; Female; Gestational A | 1989 |
Placental alcohol metabolism in chronic alcohol abuse.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Female; Humans; Pl | 1989 |
Disposition of ethanol and acetaldehyde in late pregnant rats and their fetuses.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Amniotic Fluid; Animals; Ethanol; Femal | 1989 |
Acetaldehyde production and transfer by the perfused human placental cotyledon.
Topics: Acetaldehyde; Ethanol; Female; Fetus; Humans; Maternal-Fetal Exchange; Oxidation-Reduction; Perfusio | 1988 |
Mechanisms of fetal alcohol effects: role of acetaldehyde.
Topics: Acetaldehyde; Animals; Cyanamide; Embryo Loss; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Pr | 1988 |
Determination of adenosine in fetal perfusates of human placental cotyledons using fluorescence derivatization and reversed-phase high-performance liquid chromatography.
Topics: Acetaldehyde; Adenosine; Chromatography, High Pressure Liquid; Female; Fetal Blood; Humans; Perfusio | 1988 |
Disposition of acute, multiple-dose ethanol in the near-term pregnant ewe.
Topics: Acetaldehyde; Amniotic Fluid; Animals; Dose-Response Relationship, Drug; Ethanol; Extraembryonic Mem | 1987 |
Alcohol and acetaldehyde in rat's milk following ethanol administration.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Animals; Ethanol; Female; Kineti | 1986 |
[Role of ethanol in perinatal pathology].
Topics: Acetaldehyde; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetus; Guinea Pigs; Humans | 1986 |
Pharmacokinetics of ethanol and its metabolite, acetaldehyde, and fetolethality in the third-trimester pregnant guinea pig for oral administration of acute, multiple-dose ethanol.
Topics: Acetaldehyde; Amniotic Fluid; Animals; Brain; Ethanol; Female; Fetal Blood; Fetal Death; Gestational | 1986 |
The effects of acetaldehyde and 2,3-butanediol on rat embryos developing in vitro.
Topics: Acetaldehyde; Animals; Butylene Glycols; Embryo, Mammalian; Embryonic and Fetal Development; Female; | 1985 |
The effects of disulfiram on the experimental C3H mouse embryo.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Disulfiram; DNA; Embryo, Mammalian; Female; Fetu | 1985 |
An in vitro model of acetaldehyde metabolism by rodent conceptuses.
Topics: Acetaldehyde; Animals; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic Development; | 1985 |
Disposition of ethanol in maternal blood, fetal blood, and amniotic fluid of third-trimester pregnant ewes.
Topics: Acetaldehyde; Amniotic Fluid; Animals; Blood; Disease Models, Animal; Ethanol; Female; Fetal Blood; | 1985 |
Human placental aldehyde dehydrogenase. Subcellular distribution and properties.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Cytosol; Female; Humans; In Vitro Techniques | 1985 |
Effects of acetaldehyde and/or ethanol on neutral amino acid transport systems in microvillous brush border membrane vesicles prepared from human placenta.
Topics: Acetaldehyde; Alanine; Amino Acids; Biological Transport, Active; Depression, Chemical; Ethanol; Fem | 1985 |
Studies on the properties of the human alcohol dehydrogenase isozymes determined by the different loci ADH1, ADH2, ADH3.
Topics: 1-Propanol; Acetaldehyde; Alcohol Oxidoreductases; Alcohols; Aldehyde Oxidoreductases; Butanols; Chl | 1973 |
Ethanol and acetaldehyde in the milk and peripheral blood of lactating women after ethanol administration.
Topics: Acetaldehyde; Administration, Oral; Ethanol; Female; Humans; Lactation; Milk, Human; Pregnancy; Time | 1974 |
Metabolism of ethanol and acetaldehyde in intact rats during pregnancy.
Topics: Acetaldehyde; Animals; Chromatography, Gas; Ethanol; Female; In Vitro Techniques; Injections, Intrap | 1974 |
Aldehyde oxidase activity during the perinatal period.
Topics: Acetaldehyde; Aldehydes; Animals; Animals, Newborn; Female; Fetus; Indophenol; Liver; Oxidoreductase | 1969 |