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acetaldehyde and Nerve Degeneration

acetaldehyde has been researched along with Nerve Degeneration in 4 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"We propose that the structural epitope AA-AGE is an important toxic moiety for neuronal cells in alcoholism."1.33Cytotoxicity of acetaldehyde-derived advanced glycation end-products (AA-AGE) in alcoholic-induced neuronal degeneration. ( Saito, T; Takeuchi, M, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takeuchi, M1
Saito, T1
Phillips, S1
Cragg, B1
Rintala, J1
Jaatinen, P1
Lu, W1
Sarviharju, M1
Eriksson, CJ1
Laippala, P1
Kiianmaa, K1
Hervonen, A1
Phillips, SC1

Other Studies

4 other studies available for acetaldehyde and Nerve Degeneration

ArticleYear
Cytotoxicity of acetaldehyde-derived advanced glycation end-products (AA-AGE) in alcoholic-induced neuronal degeneration.
    Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:12 Suppl

    Topics: Acetaldehyde; Alcoholism; Animals; Antibodies; Cells, Cultured; Central Nervous System Depressants;

2005
Does consumption of alcohol in the presence of disulfiram cause brain damage?
    Toxicology and applied pharmacology, 1983, Jun-15, Volume: 69, Issue:1

    Topics: Acetaldehyde; Alcohol Drinking; Animals; Brain Diseases; Disulfiram; Ethanol; Male; Nerve Degenerati

1983
Effects of lifelong ethanol consumption on cerebellar layer volumes in AA and ANA rats.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:2

    Topics: Acetaldehyde; Age Factors; Alcoholism; Animals; Brain Mapping; Cerebellar Cortex; Cerebellum; Ethano

1997
Can brain lesions occur in experimental animals by administration of ethanol or acetaldehyde?
    Acta medica Scandinavica. Supplementum, 1987, Volume: 717

    Topics: Acetaldehyde; Administration, Inhalation; Alcoholism; Animals; Brain; Disease Models, Animal; Disulf

1987