acetaldehyde has been researched along with Muscle Contraction in 20 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present results strongly suggest that acetaldehyde stimulates human airway mast cells to release histamine, which may be involved in bronchial smooth muscle contraction following alcohol consumption." | 3.72 | Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction. ( Fukushima, C; Kawano, T; Kohno, S; Kondo, Y; Machida, I; Matsuse, H; Mitsuta, K; Obase, Y; Saeki, S; Shimoda, T; Tomari, S, 2004) |
| "Ethanol did not affect resting tension but acetaldehyde and ethanol suppressed bladder muscle contractions." | 3.70 | Effects of ethanol and its metabolite acetaldehyde on responses of the rat bladder. ( Kim, HJ; Lee, G; Lee, HW; Lee, JG; Moon, H; Sohng, I, 1999) |
| " TIQs contracted isolated saphenous vein strips, behaving as total agonists; the dose-response curves were displaced to the right by phentolamine and to the left by cocaine (potentiation factor: 2." | 1.25 | Preparation and pharmacological activity of the condensation product of adrenaline with acetaldehyde. ( Osswald, W; Polónia, J; Polónia, MA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (60.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oba, T | 2 |
| Maeno, Y | 2 |
| Kawano, T | 1 |
| Matsuse, H | 1 |
| Kondo, Y | 1 |
| Machida, I | 1 |
| Saeki, S | 1 |
| Tomari, S | 1 |
| Mitsuta, K | 1 |
| Obase, Y | 1 |
| Fukushima, C | 1 |
| Shimoda, T | 1 |
| Kohno, S | 1 |
| Ishida, K | 1 |
| Altura, BM | 2 |
| Altura, BT | 2 |
| Carella, A | 2 |
| Khan, AR | 1 |
| Momose, Y | 3 |
| Takeda, R | 3 |
| Schuckit, MA | 1 |
| Brown, RA | 1 |
| Savage, AO | 1 |
| McCrohan, CR | 1 |
| Mills, JD | 1 |
| Cheng, SC | 1 |
| Bailey, SE | 1 |
| Kim, HJ | 2 |
| Moon, H | 1 |
| Sohng, I | 2 |
| Lee, HW | 1 |
| Lee, G | 2 |
| Lee, JG | 1 |
| Kim, JJ | 1 |
| Koh, SK | 1 |
| Puszkin, S | 1 |
| Rubin, E | 1 |
| Osswald, W | 1 |
| Polónia, J | 1 |
| Polónia, MA | 1 |
| Haji, A | 1 |
| Beckner, JS | 1 |
| Hudgins, PM | 1 |
| Egle, JL | 1 |
| Nakano, J | 2 |
| Prancan, AV | 1 |
| Kessinger, JM | 1 |
| Walsh, MJ | 1 |
| Hollander, PB | 1 |
| Truitt, EB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Asian Flushing Syndrome With Topical Alpha Agonists[NCT03497442] | Early Phase 1 | 20 participants (Actual) | Interventional | 2018-07-12 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetaldehyde and Muscle Contraction
| Article | Year |
|---|---|
Differential contribution of clinical amounts of acetaldehyde to skeletal and cardiac muscle dysfunction in alcoholic myopathy.
Topics: Acetaldehyde; Alcohol Drinking; Cardiomyopathy, Alcoholic; Central Nervous System Depressants; Ethan | 2005 |
19 other studies available for acetaldehyde and Muscle Contraction
| Article | Year |
|---|---|
Acetaldehyde alters Ca2+-release channel gating and muscle contraction in a dose-dependent manner.
Topics: Acetaldehyde; Animals; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Ion Channel G | 2004 |
Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction.
Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Bronchoconstriction; Female; Histamine Antagonists; Hi | 2004 |
Ethanol produces coronary vasospasm: evidence for a direct action of ethanol on vascular muscle.
Topics: Acetaldehyde; Animals; Coronary Vasospasm; Dogs; Ethanol; Female; Male; Muscle Contraction; Muscle, | 1983 |
Influence of ethanol and acetaldehyde on electro-mechanical coupling of skeletal muscle fibers.
Topics: Acetaldehyde; Action Potentials; Animals; Calcium; Ethanol; Membrane Potentials; Muscle Contraction; | 1981 |
The inhibitory action of acetaldehyde on the tonic component of the potassium-induced contracture in the guinea-pig taenia caeci.
Topics: Acetaldehyde; Animals; Calcium; Carbachol; Cecum; Electric Stimulation; Guinea Pigs; In Vitro Techni | 1982 |
Biological markers: metabolism and acute reactions to alcohol in sons of alcoholics.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Ethanol; Humans; Male; Muscle Contraction; Prospec | 1980 |
Effects of acute acetaldehyde, chronic ethanol, and pargyline treatment on agonist responses of the rat aorta.
Topics: Acetaldehyde; Aldehyde Oxidoreductases; Animals; Aorta; Central Nervous System Depressants; Diet; Dr | 1996 |
Inhibition of feeding responses by the molluscicide, metaldehyde.
Topics: Acetaldehyde; Animals; Central Nervous System; Feeding Behavior; Lymnaea; Molluscacides; Motor Neuro | 1995 |
Effects of ethanol and its metabolite acetaldehyde on responses of the rat bladder.
Topics: Acetaldehyde; Adenosine Triphosphate; Animals; Bethanechol; Central Nervous System Depressants; Dose | 1999 |
Effects of acetaldehyde on responses of rabbit corpus cavernosal smooth muscle.
Topics: Acetaldehyde; Animals; Bethanechol; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation | 2000 |
Adenosine diphosphate effect on contractility of human muscle actomyosin: inhibition by ethanol and acetaldehyde.
Topics: Acetaldehyde; Actins; Actomyosin; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Tripho | 1975 |
Effects of acetaldehyde on electrical and mechanical activities of guinea-pig taenia coli.
Topics: Acetaldehyde; Acetylcholine; Animals; Barium; Calcium; Colon; Drug Interactions; Female; Guinea Pigs | 1978 |
Acetaldehyde on vascular smooth muscle: possible role in vasodilator action of ethanol.
Topics: Acetaldehyde; Animals; Blood Vessels; Calcium; Dose-Response Relationship, Drug; Epinephrine; Ethano | 1978 |
Preparation and pharmacological activity of the condensation product of adrenaline with acetaldehyde.
Topics: Acetaldehyde; Animals; Autonomic Fibers, Preganglionic; Blood Pressure; Chromatography, Gas; Chromat | 1975 |
Effects of acetaldehyde on contractile response to nerve stimulation in guinea-pig vas deferens.
Topics: Acetaldehyde; Animals; Electric Stimulation; Electrodes; Guinea Pigs; Hexamethonium Compounds; In Vi | 1990 |
Effects of acetaldehyde, propionaldehyde, formaldehyde and acrolein on contractility, 14C-norepinephrine and 45calcium binding in isolated smooth muscle.
Topics: Acetaldehyde; Acrolein; Aldehydes; Animals; Aorta; Binding Sites; Calcium; Calcium Radioisotopes; Ca | 1974 |
Effects of adrenergic blockade on cardiovascular responses to ethanol and acetaldehyde.
Topics: Acetaldehyde; Animals; Arteries; Blood Pressure; Cardiovascular System; Catecholamines; Dogs; Drug A | 1972 |
Cardiovascular effects of ethanol, its congeners and synthetic bourbon in dogs.
Topics: Acetaldehyde; Acetates; Alcoholic Beverages; Animals; Anti-Arrhythmia Agents; Blood Pressure; Chroma | 1972 |
Sympathomimetic effects of acetaldehyde on the electrical and contractile characteristics of isolated left atria of guinea pigs.
Topics: Acetaldehyde; Animals; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Me | 1969 |