acetaldehyde has been researched along with Lung Neoplasms in 14 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Consistent with this concept, treatment of lung adenocarcinoma cells with ALDH2 agonist Alda-1 suppressed the proliferation, stemness and migration features of lung adenocarcinoma cells." | 1.51 | ALDH2 Repression Promotes Lung Tumor Progression via Accumulated Acetaldehyde and DNA Damage. ( Deng, J; Guo, W; Hu, M; Jing, B; Kuang, Y; Li, K; Li, Z; Liao, Y; Ling, J; Song, H; Sun, A; Sun, B; Wang, L; Wang, Q; Wang, T; Wang, Y; Xu, D; Yao, F; Zhu, L, 2019) |
| "Acetaldehyde was also released by the medium, but at relatively lower levels than the other three compounds, and was also generated by the CALU-1 and NL20 cell cultures in proportions to the number of cells in the medium." | 1.35 | Quantification of acetaldehyde and carbon dioxide in the headspace of malignant and non-malignant lung cells in vitro by SIFT-MS. ( Pysanenko, A; Smith, D; Spanel, P; Sulé-Suso, J, 2009) |
| " Similar dose-response curves were found for both metabolites." | 1.30 | Ifosfamide cytotoxicity on human tumor and renal cells: role of chloroacetaldehyde in comparison to 4-hydroxyifosfamide. ( Brüggemann, SK; Kisro, J; Wagner, T, 1997) |
| " As compared with the values obtained on day 1, on day 5 the terminal half-life and AUC values determined for IF were reduced by 30% (6." | 1.29 | Comparative pharmacokinetics of ifosfamide, 4-hydroxyifosfamide, chloroacetaldehyde, and 2- and 3-dechloroethylifosfamide in patients on fractionated intravenous ifosfamide therapy. ( Kurowski, V; Wagner, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, K | 1 |
| Guo, W | 1 |
| Li, Z | 1 |
| Wang, Y | 1 |
| Sun, B | 1 |
| Xu, D | 1 |
| Ling, J | 1 |
| Song, H | 1 |
| Liao, Y | 1 |
| Wang, T | 2 |
| Jing, B | 1 |
| Hu, M | 1 |
| Kuang, Y | 1 |
| Wang, Q | 1 |
| Yao, F | 1 |
| Sun, A | 1 |
| Zhu, L | 1 |
| Wang, L | 1 |
| Deng, J | 1 |
| Schumer, EM | 1 |
| Trivedi, JR | 1 |
| van Berkel, V | 1 |
| Black, MC | 1 |
| Li, M | 1 |
| Fu, XA | 1 |
| Bousamra, M | 1 |
| Sulé-Suso, J | 2 |
| Pysanenko, A | 1 |
| Spanel, P | 2 |
| Smith, D | 2 |
| Yang, M | 1 |
| Coles, BF | 1 |
| Delongchamp, R | 1 |
| Lang, NP | 1 |
| Kadlubar, FF | 1 |
| El Haj, A | 1 |
| Brennan, P | 1 |
| Lin, JS | 1 |
| Chuang, KT | 1 |
| Huang, MS | 1 |
| Wei, KM | 1 |
| Pankow, JF | 1 |
| Watanabe, KH | 1 |
| Toccalino, PL | 1 |
| Luo, W | 1 |
| Austin, DF | 1 |
| Braven, J | 1 |
| Bonker, GJ | 1 |
| Fenner, ML | 1 |
| Tonge, BL | 1 |
| Toth, B | 1 |
| Patil, K | 1 |
| Kurowski, V | 1 |
| Wagner, T | 2 |
| Brüggemann, SK | 1 |
| Kisro, J | 1 |
| Henning, T | 1 |
| Brischwein, M | 1 |
| Baumann, W | 1 |
| Ehret, R | 1 |
| Freund, I | 1 |
| Kammerer, R | 1 |
| Lehmann, M | 1 |
| Schwinde, A | 1 |
| Wolf, B | 1 |
| Kitson, TM | 1 |
14 other studies available for acetaldehyde and Lung Neoplasms
| Article | Year |
|---|---|
ALDH2 Repression Promotes Lung Tumor Progression via Accumulated Acetaldehyde and DNA Damage.
Topics: Acetaldehyde; Acetic Acid; Adenocarcinoma of Lung; Aldehyde Dehydrogenase, Mitochondrial; Animals; C | 2019 |
High sensitivity for lung cancer detection using analysis of exhaled carbonyl compounds.
Topics: Acetaldehyde; Acetoin; Aged; Aldehydes; Biomarkers, Tumor; Breath Tests; Butanones; Case-Control Stu | 2015 |
Quantification of acetaldehyde and carbon dioxide in the headspace of malignant and non-malignant lung cells in vitro by SIFT-MS.
Topics: Acetaldehyde; Carbon Dioxide; Cell Line, Tumor; Humans; Lung; Lung Neoplasms; Mass Spectrometry | 2009 |
Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue.
Topics: Acetaldehyde; Adolescent; Adult; Age Factors; Aged; Alcohol Dehydrogenase; Biotransformation; Chroma | 2002 |
Quantification of acetaldehyde released by lung cancer cells in vitro using selected ion flow tube mass spectrometry.
Topics: Acetaldehyde; Cell Count; Ions; Lung Neoplasms; Mass Spectrometry; Tumor Cells, Cultured; Volatiliza | 2003 |
Commentary: Mendelian randomization and gene-environment interaction.
Topics: Acetaldehyde; Alcohol Drinking; Behavior; Causality; Diet; Environment; Genetic Predisposition to Di | 2004 |
Emission of ethylene oxide during frying of foods in soybean oil.
Topics: Acetaldehyde; Cooking; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hot Temperature; Humans | 2007 |
Calculated cancer risks for conventional and "potentially reduced exposure product" cigarettes.
Topics: Acetaldehyde; Acrylonitrile; Biomarkers; Butadienes; Carcinogens; Humans; Lung; Lung Neoplasms; Risk | 2007 |
The mechanism of carcinogenesis by tobacco smoke. Some experimental observations and a hypothesis.
Topics: Acetaldehyde; Bronchial Neoplasms; Carcinogens; Chemical Phenomena; Chemistry; Chromatography; Cyste | 1967 |
Gyromitrin as a tumor inducer.
Topics: Acetaldehyde; Adenocarcinoma; Adenoma; Animals; Basidiomycota; Carcinogens; Carcinoma, Squamous Cell | 1981 |
Comparative pharmacokinetics of ifosfamide, 4-hydroxyifosfamide, chloroacetaldehyde, and 2- and 3-dechloroethylifosfamide in patients on fractionated intravenous ifosfamide therapy.
Topics: Acetaldehyde; Adult; Aged; Carcinoma, Bronchogenic; Chromatography, Gas; Chromatography, High Pressu | 1993 |
Ifosfamide cytotoxicity on human tumor and renal cells: role of chloroacetaldehyde in comparison to 4-hydroxyifosfamide.
Topics: Acetaldehyde; Carcinoma, Non-Small-Cell Lung; Cell Survival; Cells, Cultured; Dose-Response Relation | 1997 |
Approach to a multiparametric sensor-chip-based tumor chemosensitivity assay.
Topics: Acetaldehyde; Antibiotics, Antineoplastic; Biosensing Techniques; Breast Neoplasms; Doxorubicin; Dru | 2001 |
Disulfiram and cigarettes.
Topics: Acetaldehyde; Disulfiram; Ditiocarb; Drug Interactions; Humans; Lung Neoplasms; Smoking | 1978 |