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acetaldehyde and Liver Steatosis

acetaldehyde has been researched along with Liver Steatosis in 25 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Research Excerpts

ExcerptRelevanceReference
" To investigate the effect of liver injury on the removal and the production of acetaldehyde, we produced fibrosis and cirrhosis (by chronic administration of carbon tetrachloride) and fatty liver (with very small doses of dimethylnitrosamine) in rats."3.67High levels of acetaldehyde in nonalcoholic liver injury after threonine or ethanol administration. ( Baraona, E; Hernández-Muñoz, R; Lieber, CS; Ma, XL, 1989)
"GGT indicates Alcohol Abuse only in background of normal LFT."1.72Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease. ( BhatB, NM, 2022)
"24% were in steatosis,32% were in steatohepatitis, while 44% were in cirrhosis."1.72Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease. ( BhatB, NM, 2022)
"Unlike the action of alcohol treatment on fatty liver, BFSP administration attenuated lipid droplet accumulation in hepatocytes."1.38Hepatoprotective effects on alcoholic liver disease of fermented silkworms with Bacillus subtilis and Aspergillus kawachii. ( Cha, JY; Cho, YS; Kim, YS; Moon, HI, 2012)
"No acetaldehyde adduct was detected in the control rats that were pair-fed with isocaloric amounts of dextrose."1.30Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease. ( Li, CJ; Lin, RC; Nanji, AA; Siakotos, AN, 1997)
" To investigate the effect of liver injury on the removal and the production of acetaldehyde, we produced fibrosis and cirrhosis (by chronic administration of carbon tetrachloride) and fatty liver (with very small doses of dimethylnitrosamine) in rats."1.28High levels of acetaldehyde in nonalcoholic liver injury after threonine or ethanol administration. ( Baraona, E; Hernández-Muñoz, R; Lieber, CS; Ma, XL, 1989)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199013 (52.00)18.7374
1990's4 (16.00)18.2507
2000's1 (4.00)29.6817
2010's6 (24.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
BhatB, NM1
Choi, RY1
Woo, MJ1
Ham, JR1
Lee, MK1
Millonig, G1
Praun, S1
Netzer, M1
Baumgartner, C1
Dornauer, A1
Mueller, S1
Villinger, J1
Vogel, W1
Yang, K1
Feng, C1
Lip, H1
Bruce, WR1
O'Brien, PJ1
Lorenzi, R1
Andrades, ME1
Bortolin, RC1
Nagai, R1
Dal-Pizzol, F1
Moreira, JC1
Cha, JY1
Kim, YS1
Moon, HI1
Cho, YS1
Thomes, PG1
Osna, NA1
Davis, JS1
Donohue, TM1
Renger, F1
Lieber, CS7
Matysiak-Budnik, T1
Jokelainen, K1
Kärkkäinen, P1
Mäkisalo, H1
Ohisalo, J1
Salaspuro, M1
Parkkila, S2
Niemelä, O2
Li, CJ1
Nanji, AA1
Siakotos, AN1
Lin, RC1
Juvonen, RO1
Viitala, K1
Gelboin, HV1
Pasanen, M1
Kakumu, S1
Leevy, CM3
Ugarte, G1
Iturriaga, H1
Teschke, R1
Hasumura, Y1
Decarli, LM1
Zetterman, RK1
Uppal, R1
Rosman, A1
Hernández, R1
Baraona, E2
Ma, XL1
Hernández-Muñoz, R1
Nakahata, H1
Hirai, Y1
Kumasaka, Y1
Miyazawa, T1
Nakamura, T1
Imamura, K1
Makino, I1
Takebe, K1
Kudo, H1
Sorrell, MF1
Westerfeld, WW1
Bloom, RJ1

Reviews

8 reviews available for acetaldehyde and Liver Steatosis

ArticleYear
[Alcohol and the liver].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1981, Aug-15, Volume: 36, Issue:16

    Topics: Acetaldehyde; Carbohydrate Metabolism; Enzyme Induction; Fatty Liver; gamma-Glutamyltransferase; Hep

1981
Metabolic effects of ethanol on the liver and other digestive organs.
    Clinics in gastroenterology, 1981, Volume: 10, Issue:2

    Topics: Acetaldehyde; Amino Acids; Aminobutyrates; Biotransformation; Carcinogens; Digestive System; Enzyme

1981
[Current aspects of alcohol-induced liver damage].
    Duodecim; laaketieteellinen aikakauskirja, 1995, Volume: 111, Issue:13

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Cytochrome P-450 Enzyme System; Fatty Liver; Female; Hepatitis

1995
Metabolic pathways of alcohol in the liver.
    Frontiers of gastrointestinal research, 1976, Volume: 2

    Topics: Acetaldehyde; Acetates; Alcohol Oxidoreductases; Alcoholism; Animals; Bile Acids and Salts; Catalase

1976
Differences in hepatic and metabolic changes after acute and chronic alcohol consumption.
    Federation proceedings, 1975, Volume: 34, Issue:11

    Topics: Acetaldehyde; Acetates; Acute Disease; Alcohol Oxidoreductases; Alcoholism; Animals; Catalase; Chron

1975
Immunologic reactivity and alcoholic liver disease.
    Bulletin of the New York Academy of Medicine, 1975, Volume: 51, Issue:4

    Topics: Acetaldehyde; Alcoholism; Antigen-Antibody Reactions; B-Lymphocytes; Caffeine; Chemical and Drug Ind

1975
Alcohol and the liver: metabolism of ethanol, metabolic effects and pathogenesis of injury.
    Acta medica Scandinavica. Supplementum, 1985, Volume: 703

    Topics: Acetaldehyde; Acetates; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Blood G

1985
Metabolic effects produced by alcohol in the liver and other tissues.
    Advances in internal medicine, 1968, Volume: 14

    Topics: Acetaldehyde; Acetates; Alcoholism; Coenzymes; Deficiency Diseases; Dietary Carbohydrates; Enzymes;

1968

Other Studies

17 other studies available for acetaldehyde and Liver Steatosis

ArticleYear
Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Acetaldehyde; Adult; Alcoholism; Biomarkers; Fatty Liver; Humans; Immunoglobulin A; Immunoglobulin G

2022
Anti-steatotic and anti-inflammatory effects of Hovenia dulcis Thunb. extracts in chronic alcohol-fed rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Acetaldehyde; Animals; Anti-Inflammatory Agents; Cytochrome P-450 CYP2E1; Down-Regulation; Ethanol;

2017
Non-invasive diagnosis of liver diseases by breath analysis using an optimized ion-molecule reaction-mass spectrometry approach: a pilot study.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2010, Volume: 15, Issue:4

    Topics: Acetaldehyde; Adult; Aged; Biomarkers; Breath Tests; Butadienes; Ethanol; Fatty Liver; Fatty Liver,

2010
Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde.
    Chemico-biological interactions, 2011, May-30, Volume: 191, Issue:1-3

    Topics: Acetaldehyde; Animals; Copper; Fatty Liver; Glutathione; Glyceraldehyde; Glyoxal; Hepatocytes; Hydro

2011
Oxidative damage in the liver of rats treated with glycolaldehyde.
    International journal of toxicology, 2011, Volume: 30, Issue:2

    Topics: Acetaldehyde; Animals; Catalase; Fatty Liver; Glycation End Products, Advanced; Injections, Intraven

2011
Hepatoprotective effects on alcoholic liver disease of fermented silkworms with Bacillus subtilis and Aspergillus kawachii.
    International journal of food sciences and nutrition, 2012, Volume: 63, Issue:5

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Animals; Antioxidants; Aspartate Amin

2012
Cellular steatosis in ethanol oxidizing-HepG2 cells is partially controlled by the transcription factor, early growth response-1.
    The international journal of biochemistry & cell biology, 2013, Volume: 45, Issue:2

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Cytochrome P-450 CYP2E1; Early Growth Response Protein 1; Ethan

2013
Medical disorders of alcoholism. Pathogenesis and treatment.
    Major problems in internal medicine, 1982, Volume: 22

    Topics: Acetaldehyde; Acetates; Alcoholism; Amino Acids; Animals; Arteriosclerosis; Blood; Brain; Digestion;

1982
Hepatotoxicity and absorption of extrahepatic acetaldehyde in rats.
    The Journal of pathology, 1996, Volume: 178, Issue:4

    Topics: Absorption; Acetaldehyde; Animals; Chemical and Drug Induced Liver Injury; Colon; Dose-Response Rela

1996
Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:3

    Topics: Acetaldehyde; Aldehydes; Animals; Antibodies; Corn Oil; Dietary Fats; Fatty Liver; Fish Oils; Humans

1997
Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases.
    Journal of hepatology, 2000, Volume: 33, Issue:6

    Topics: Acetaldehyde; Adipose Tissue; Adult; Aldehydes; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2

2000
Lymphocyte cytotoxicity in alcoholic hepatitis.
    Gastroenterology, 1977, Volume: 72, Issue:4 Pt 1

    Topics: Acetaldehyde; Alcoholism; Antigen-Antibody Reactions; Biopsy; Cell Line; Culture Techniques; Cytotox

1977
Effects of liver disease on red blood cell acetaldehyde in alcoholics and non-alcoholics.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: Acetaldehyde; Alcohol Drinking; Erythrocytes; Fatty Liver; Humans; Liver Cirrhosis; Liver Cirrhosis,

1991
High levels of acetaldehyde in nonalcoholic liver injury after threonine or ethanol administration.
    Hepatology (Baltimore, Md.), 1989, Volume: 10, Issue:6

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Carbon Tetrachloride; Dimethylnitrosamine; Ethanol;

1989
[Disulfiram-like reactions resulting from the administration of cephem antibiotics with methyltetrazolethiol moiety examined by using different doses].
    The Japanese journal of antibiotics, 1986, Volume: 39, Issue:3

    Topics: Acetaldehyde; Aldehyde Oxidoreductases; Animals; Cefoperazone; Disulfiram; Ethanol; Fatty Liver; Liv

1986
Lymphocyte transformation and alcoholic liver injury.
    Gastroenterology, 1972, Volume: 63, Issue:6

    Topics: Acetaldehyde; Alcoholism; Cells, Cultured; Chemical and Drug Induced Liver Injury; DNA; Ethanol; Fat

1972
[Metabolic routes of ethanol].
    Archivos de biologia y medicina experimentales, 1969, Volume: 3, Issue:Suppl 3

    Topics: Acetaldehyde; Animals; Caproates; Ethanol; Fatty Liver; Fructose-Bisphosphate Aldolase; Glyceraldehy

1969