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acetaldehyde and Liver Dysfunction

acetaldehyde has been researched along with Liver Dysfunction in 22 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Research Excerpts

ExcerptRelevanceReference
"Phenobarbital pretreatment of the rats did not affect any of these kinetic parameters."1.28Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol. ( Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M, 1992)
" The enzymes involved in the toxic metabolic pathway have been investigated in this study."1.28Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol. ( Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M, 1992)
"The mechanism by which alcohol abuse causes the morphologic abnormalities is not known."1.27Red cell morphology in alcoholics: a new test for alcohol abuse. ( Bailey, AR; Homaidan, FR; Kricka, LJ; Whitehead, TP, 1986)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19909 (40.91)18.7374
1990's10 (45.45)18.2507
2000's1 (4.55)29.6817
2010's1 (4.55)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Yang, XY1
Luo, J1
Chen, BY1
Chen, Q1
Liu, ZZ1
Ye, QF1
Millonig, G1
Praun, S1
Netzer, M1
Baumgartner, C1
Dornauer, A1
Mueller, S1
Villinger, J1
Vogel, W1
Holstege, A1
Bedossa, P1
Poynard, T1
Kollinger, M1
Chaput, JC1
Houglum, K1
Chojkier, M1
Svegliati-Baroni, G1
Baraona, E2
Rosman, AS1
Lieber, CS4
Viitala, K2
Israel, Y1
Blake, JE1
Niemelä, O2
Parkkila, S1
Juvonen, RO1
Gelboin, HV1
Pasanen, M1
Moura, D1
Azevedo, I1
Osswald, W1
Macdonald, CM1
Dow, J1
Moore, MR1
Bossone, CM1
Kaminsky, LS1
Fraser, JM1
Seaman, M1
Dunbar, D1
Worrall, S3
De Jersey, J3
Shanley, BC3
Wilce, PA3
Uppal, R1
Rosman, A1
Hernández, R1
Trudell, JR1
Ardies, CM1
Anderson, WR1
Kakuma, S1
Leevy, CB1
Frank, O1
Baker, H1
Homaidan, FR1
Kricka, LJ1
Bailey, AR1
Whitehead, TP1
Thompson, RP1
Younes, M1
Strubelt, O1
Matthewson, K1
Al Mardini, H1
Bartlett, K1
Record, CO1

Reviews

3 reviews available for acetaldehyde and Liver Dysfunction

ArticleYear
Role of oxidative stress and antioxidant therapy in alcoholic and nonalcoholic liver diseases.
    Advances in pharmacology (San Diego, Calif.), 1997, Volume: 38

    Topics: Acetaldehyde; Animals; Antioxidants; Humans; Lipid Peroxidation; Liver Diseases; Liver Diseases, Alc

1997
Measuring the damage--ethanol and the liver.
    Gut, 1986, Volume: 27, Issue:7

    Topics: Acetaldehyde; Aldehyde Oxidoreductases; Ethanol; Female; Gastric Emptying; Humans; Intestinal Absorp

1986
Metabolic effects produced by alcohol in the liver and other tissues.
    Advances in internal medicine, 1968, Volume: 14

    Topics: Acetaldehyde; Acetates; Alcoholism; Coenzymes; Deficiency Diseases; Dietary Carbohydrates; Enzymes;

1968

Other Studies

19 other studies available for acetaldehyde and Liver Dysfunction

ArticleYear
[Research progress of acetaldehyde dehydrogenase 2 in liver diseases].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2022, Dec-20, Volume: 30, Issue:12

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Humans; Liver Diseases

2022
Non-invasive diagnosis of liver diseases by breath analysis using an optimized ion-molecule reaction-mass spectrometry approach: a pilot study.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2010, Volume: 15, Issue:4

    Topics: Acetaldehyde; Adult; Aged; Biomarkers; Breath Tests; Butadienes; Ethanol; Fatty Liver; Fatty Liver,

2010
Acetaldehyde-modified epitopes in liver biopsy specimens of alcoholic and nonalcoholic patients: localization and association with progression of liver fibrosis.
    Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:2

    Topics: Acetaldehyde; Adult; Antibody Specificity; Biopsy, Needle; Epitopes; Female; Humans; Immunohistochem

1994
Collagen-acetaldehyde adducts in alcoholic and nonalcoholic liver diseases.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:1 Pt 1

    Topics: Acetaldehyde; Adult; Aged; Analysis of Variance; Animals; Aspartate Aminotransferases; Collagen; gam

1994
Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: relationship to liver disease severity and alcohol consumption.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:6

    Topics: Acetaldehyde; Alcohol Drinking; Antibodies; Disease Progression; Epitopes; Female; Humans; Immunoglo

1997
Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases.
    Journal of hepatology, 2000, Volume: 33, Issue:6

    Topics: Acetaldehyde; Adipose Tissue; Adult; Aldehydes; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2

2000
Hepatotoxicity of the condensation product of adrenaline with acetaldehyde.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:4

    Topics: Acetaldehyde; Animals; Chemical and Drug Induced Liver Injury; Epinephrine; Liver; Liver Diseases; M

1977
A possible protective role for sulphydryl compounds in acute alcoholic liver injury.
    Biochemical pharmacology, 1977, Aug-15, Volume: 26, Issue:16

    Topics: Acetaldehyde; Alcoholic Intoxication; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dos

1977
The liver: a pharmacologic perspective.
    The Nursing clinics of North America, 1977, Volume: 12, Issue:2

    Topics: Acetaldehyde; Alcoholism; Chemical and Drug Induced Liver Injury; Diuretics; Drug-Related Side Effec

1977
Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol.
    Biochemical pharmacology, 1992, Nov-03, Volume: 44, Issue:9

    Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Biotransformation; Chemical and Drug Induced Liver In

1992
Antibodies against acetaldehyde-modified epitopes: presence in alcoholic, non-alcoholic liver disease and control subjects.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1990, Volume: 25, Issue:5

    Topics: Acetaldehyde; Alcohol Drinking; Autoantibodies; Blood Proteins; Carcinoma, Hepatocellular; Enzyme-Li

1990
Antibodies against acetaldehyde-modified epitopes: an elevated IgA response in alcoholics.
    European journal of clinical investigation, 1991, Volume: 21, Issue:1

    Topics: Acetaldehyde; Alcoholism; Epitopes; Hemoglobins; Humans; Immunoglobulin A; Liver; Liver Diseases; Li

1991
Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Cattle; Enzyme-Linked Immunosorbent Assay; Hemo

1991
Effects of liver disease on red blood cell acetaldehyde in alcoholics and non-alcoholics.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: Acetaldehyde; Alcohol Drinking; Erythrocytes; Fatty Liver; Humans; Liver Cirrhosis; Liver Cirrhosis,

1991
The effect of alcohol and anesthetic metabolites on cell membranes. A possible direct immune mechanism.
    Annals of the New York Academy of Sciences, 1991, Volume: 625

    Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Cell Membrane; Chemical and Drug Induced Live

1991
Pyridoxal phosphate annuls acetaldehyde inhibition of uridine uptake by hepatocytes.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1989, Volume: 24, Issue:1

    Topics: Acetaldehyde; Benzylamines; Depression, Chemical; Drug Evaluation; Humans; In Vitro Techniques; Live

1989
Red cell morphology in alcoholics: a new test for alcohol abuse.
    Blood cells, 1986, Volume: 11, Issue:3

    Topics: Acetaldehyde; Adult; Alcoholism; Aspartate Aminotransferases; Erythrocyte Volume; Erythrocytes; Eryt

1986
Enhancement of hypoxic liver damage by ethanol. Involvement of xanthine oxidase and the role of glycolysis.
    Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18

    Topics: Acetaldehyde; Adenosine Triphosphate; Alanine Transaminase; Allopurinol; Animals; Ethanol; Glycolysi

1987
Impaired acetaldehyde metabolism in patients with non-alcoholic liver disorders.
    Gut, 1986, Volume: 27, Issue:7

    Topics: Acetaldehyde; Adult; Aged; Aldehyde Dehydrogenase; Chromatography, Gas; Cytosol; Ethanol; Female; Hu

1986