acetaldehyde has been researched along with Liver Diseases, Alcoholic in 149 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In spite of continuing alcohol abuse, only a fraction of all alcoholics will develop alcoholic hepatitis and eventually cirrhosis." | 2.38 | [Pathogenesis of alcoholic liver disease]. ( Lauterburg, BH, 1992) |
| "Acetaldehyde was found to be transported in the blood mainly bound reversibly to 2 components of the red blood cells (RBC): a) hemoglobin, which provides binding of a high affinity, but low capacity, and b) a non-protein component (presumably cysteine), which has a lower affinity but a higher capacity." | 2.38 | Contribution of exogenous ethanol and endogenous substrates to acetaldehyde-adduct formation in liver injury. ( Baraona, E; Behrens, UJ; Hernández-Muñoz, R; Lieber, CS; Ma, XL; Uppal, R, 1991) |
| "Acetaldehyde also promotes glutathione depletion, free-radical mediated toxicity, lipid peroxidation and hepatic collagen synthesis." | 2.38 | Biochemical mechanisms of alcohol-induced hepatic injury. ( Lieber, CS, 1991) |
| "1." | 2.38 | The genesis of alcoholic brain tissue injury. ( Pratt, OE; Rooprai, HK; Shaw, GK; Thomson, AD, 1990) |
| "Acetaldehyde is a toxic material produced when alcohol is metabolized through some enzymes, and it causes endoplasmic reticulum (ER) stress, mitochondrial dysfunction, and tissue injury." | 1.91 | Hepatic progesterone receptor membrane component 1 attenuates ethanol-induced liver injury by reducing acetaldehyde production and oxidative stress. ( Baek, IJ; Hong, EJ; Jo, SL; Ko, JW; Kwun, HJ; Shin, HJ, 2023) |
| "GGT indicates Alcohol Abuse only in background of normal LFT." | 1.72 | Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease. ( BhatB, NM, 2022) |
| "24% were in steatosis,32% were in steatohepatitis, while 44% were in cirrhosis." | 1.72 | Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease. ( BhatB, NM, 2022) |
| " Severe fatty degeneration was observed during chronic administration of ethanol increasing from 4-8 weeks." | 1.39 | Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease. ( Arisawa, T; Fukumura, A; George, J; Hayashi, N; Takeuchi, M; Toshikuni, N; Tsutsumi, M, 2013) |
| "Unlike the action of alcohol treatment on fatty liver, BFSP administration attenuated lipid droplet accumulation in hepatocytes." | 1.38 | Hepatoprotective effects on alcoholic liver disease of fermented silkworms with Bacillus subtilis and Aspergillus kawachii. ( Cha, JY; Cho, YS; Kim, YS; Moon, HI, 2012) |
| "Acetaldehyde treatment of H4IIE cells led to a time- and dose-dependent increase in GCLC mRNA levels, binding of NF-kappaB and AP-1 to the GCLC promoter, and luciferase activity driven by the GCLC promoter fragment containing these binding sites." | 1.31 | Cloning and characterization of the 5'-flanking region of the rat glutamate-cysteine ligase catalytic subunit. ( Huang, ZZ; Lu, SC; Ou, X; Wang, J; Yang, H, 2001) |
| "No acetaldehyde adduct was detected in the control rats that were pair-fed with isocaloric amounts of dextrose." | 1.30 | Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease. ( Li, CJ; Lin, RC; Nanji, AA; Siakotos, AN, 1997) |
| "An acetaldehyde (AcH) adduct was prepared using rabbit low-density lipoprotein as carrier proteins." | 1.30 | An enzyme immune assay for serum anti-acetaldehyde adduct antibody using low-density lipoprotein adduct and its significance in alcoholic liver injury. ( Matsuzaki, S; Nagata, N; Nishizaki, Y; Tsuda, M; Watanabe, N, 1998) |
| "Acetaldehyde adducts were found by immunofluorescence in the centrilobular region and were focused in perivenous zone 3 of all ethanol-fed animals." | 1.29 | Centrilobular distribution of acetaldehyde and collagen in the ethanol-fed micropig. ( Chandler, CJ; Halsted, CH; Munn, RJ; Niemelä, O; Parkkila, S; Ruebner, B; Villanueva, J, 1993) |
| "Alcohol abuse is known to cause disturbances to iron homeostasis in man and is associated with elevated serum ferritin levels." | 1.29 | Effect of chronic alcohol feeding on hepatic iron status and ferritin uptake by rat hepatocytes. ( Loney, LA; Potter, BJ; Zhang, H, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (30.87) | 18.7374 |
| 1990's | 52 (34.90) | 18.2507 |
| 2000's | 27 (18.12) | 29.6817 |
| 2010's | 17 (11.41) | 24.3611 |
| 2020's | 7 (4.70) | 2.80 |
| Authors | Studies |
|---|---|
| BhatB, NM | 1 |
| Duryee, MJ | 6 |
| Aripova, N | 3 |
| Hunter, CD | 4 |
| Ruskamp, RJ | 3 |
| Tessin, MR | 3 |
| Works, DR | 3 |
| Mikuls, TR | 4 |
| Thiele, GM | 11 |
| Adhikari, R | 1 |
| Mitra, R | 1 |
| Bennett, RG | 1 |
| McVicker, BL | 1 |
| Tuma, PL | 2 |
| Jo, SL | 1 |
| Baek, IJ | 1 |
| Ko, JW | 1 |
| Kwun, HJ | 1 |
| Shin, HJ | 1 |
| Hong, EJ | 1 |
| Liang, HW | 1 |
| Yang, TY | 1 |
| Teng, CS | 1 |
| Lee, YJ | 1 |
| Yu, MH | 1 |
| Lee, HJ | 1 |
| Hsu, LS | 1 |
| Wang, CJ | 1 |
| Shuai, C | 1 |
| Xia, GQ | 1 |
| Yuan, F | 1 |
| Wang, S | 2 |
| Lv, XW | 1 |
| Zhang, FY | 1 |
| Gao, YH | 1 |
| Sasaki, Y | 1 |
| Dehnad, A | 1 |
| Fish, S | 1 |
| Sato, A | 1 |
| Jiang, J | 1 |
| Tian, J | 1 |
| Schröder, K | 1 |
| Brandes, R | 1 |
| Török, NJ | 1 |
| Hao, L | 1 |
| Sun, Q | 1 |
| Zhong, W | 1 |
| Zhang, W | 1 |
| Sun, X | 2 |
| Zhou, Z | 1 |
| Wiese, BM | 1 |
| Bowman, JR | 1 |
| Vanlandingham, JD | 1 |
| Klassen, LW | 10 |
| Thiele, GE | 1 |
| Anderson, DR | 1 |
| Han, H | 1 |
| He, Y | 1 |
| Johnson, H | 1 |
| Mishra, P | 1 |
| Lee, H | 1 |
| Ji, C | 1 |
| Pár, A | 1 |
| Pár, G | 1 |
| Luo, Z | 1 |
| Liu, H | 1 |
| Guo, R | 1 |
| Cui, R | 1 |
| Ma, X | 1 |
| Yan, M | 1 |
| Cha, JY | 2 |
| Ahn, HY | 1 |
| Cho, YS | 2 |
| Je, JY | 1 |
| Hayashi, N | 1 |
| George, J | 1 |
| Takeuchi, M | 1 |
| Fukumura, A | 1 |
| Toshikuni, N | 1 |
| Arisawa, T | 1 |
| Tsutsumi, M | 2 |
| Ceni, E | 2 |
| Mello, T | 2 |
| Galli, A | 2 |
| Zakhari, S | 1 |
| Thomes, PG | 1 |
| Donohue, TM | 1 |
| Wang, F | 1 |
| Zhang, YJ | 1 |
| Zhou, Y | 1 |
| Li, Y | 1 |
| Zhou, T | 1 |
| Zheng, J | 1 |
| Zhang, JJ | 1 |
| Li, S | 1 |
| Xu, DP | 1 |
| Li, HB | 1 |
| Wu, X | 1 |
| Wang, Y | 1 |
| Xu, R | 1 |
| Lv, X | 1 |
| Lee, JH | 1 |
| Banerjee, A | 1 |
| Ueno, Y | 1 |
| Ramaiah, SK | 1 |
| Farfán Labonne, BE | 1 |
| Gutiérrez, M | 1 |
| Gómez-Quiroz, LE | 1 |
| Konigsberg Fainstein, M | 1 |
| Bucio, L | 1 |
| Souza, V | 1 |
| Flores, O | 1 |
| Ortíz, V | 1 |
| Hernández, E | 1 |
| Kershenobich, D | 1 |
| Gutiérrez-Ruíz, MC | 1 |
| Youtz, DJ | 1 |
| Wold, LE | 1 |
| Shen, Z | 1 |
| Ajmo, JM | 1 |
| Rogers, CQ | 1 |
| Liang, X | 1 |
| Le, L | 1 |
| Murr, MM | 1 |
| Peng, Y | 1 |
| You, M | 1 |
| McKillop, IH | 1 |
| Schrum, LW | 1 |
| Rao, R | 2 |
| Guo, Y | 2 |
| Wu, XQ | 2 |
| Zhang, C | 2 |
| Liao, ZX | 2 |
| Wu, Y | 1 |
| Xia, ZY | 1 |
| Wang, H | 2 |
| Song, BJ | 1 |
| Abdelmegeed, MA | 1 |
| Yoo, SH | 1 |
| Kim, BJ | 1 |
| Jo, SA | 1 |
| Jo, I | 1 |
| Moon, KH | 1 |
| Kim, YS | 1 |
| Moon, HI | 1 |
| Shimada, S | 1 |
| Yamauchi, M | 1 |
| Takamatsu, M | 1 |
| Uetake, S | 1 |
| Ohata, M | 1 |
| Saito, S | 1 |
| Freeman, TL | 3 |
| Willis, MS | 2 |
| Tuma, DJ | 14 |
| Kuszynski, CA | 1 |
| Nakajima, T | 1 |
| Kamijo, Y | 1 |
| Tanaka, N | 1 |
| Sugiyama, E | 1 |
| Tanaka, E | 1 |
| Kiyosawa, K | 1 |
| Fukushima, Y | 1 |
| Peters, JM | 1 |
| Gonzalez, FJ | 1 |
| Aoyama, T | 1 |
| Latvala, J | 1 |
| Hietala, J | 1 |
| Koivisto, H | 1 |
| Järvi, K | 1 |
| Anttila, P | 1 |
| Niemelä, O | 12 |
| Worrall, S | 6 |
| Parkkila, S | 6 |
| Emery, PW | 1 |
| Preedy, VR | 1 |
| Seitz, HK | 3 |
| Salaspuro, M | 2 |
| Savolainen, M | 1 |
| Haber, P | 1 |
| Ishii, H | 2 |
| Teschke, R | 2 |
| Moshage, H | 1 |
| Lieber, CS | 16 |
| Kannarkat, GT | 1 |
| Crabb, DW | 1 |
| Foschi, M | 1 |
| Tarocchi, M | 1 |
| Patussi, V | 1 |
| Moraldi, L | 1 |
| Moretti, R | 1 |
| Milani, S | 1 |
| Surrenti, C | 1 |
| Jelski, W | 1 |
| Chrostek, L | 1 |
| Szmitkowski, M | 1 |
| Rao, RK | 1 |
| Purohit, V | 1 |
| Bode, JC | 1 |
| Bode, C | 1 |
| Brenner, DA | 1 |
| Choudhry, MA | 1 |
| Hamilton, F | 1 |
| Kang, YJ | 1 |
| Keshavarzian, A | 1 |
| Sartor, RB | 1 |
| Swanson, C | 1 |
| Turner, JR | 1 |
| Jenkins, W | 1 |
| Renger, F | 1 |
| Lewis, KO | 1 |
| Paton, A | 1 |
| García-Buñuel, L | 1 |
| Thurman, RG | 2 |
| Ji, S | 1 |
| Lemasters, JJ | 1 |
| Yoshihara, H | 1 |
| Sato, N | 2 |
| Kamada, T | 1 |
| Abe, H | 1 |
| Sorrell, MF | 7 |
| Hirayama, C | 1 |
| Kishimoto, Y | 1 |
| Wakushima, T | 1 |
| Murawaki, Y | 1 |
| Baraona, E | 4 |
| Nilius, R | 1 |
| Königstedt, B | 1 |
| Zipprich, B | 1 |
| Busse, HJ | 1 |
| Lorenz, G | 1 |
| Rothschild, MA | 1 |
| Oratz, M | 1 |
| Morland, J | 1 |
| Schreiber, SS | 1 |
| Burks, A | 1 |
| Martin, B | 1 |
| Yokoyama, H | 1 |
| Tuma, D | 1 |
| Ylä-Herttuala, S | 1 |
| Villanueva, J | 2 |
| Ruebner, B | 2 |
| Halsted, CH | 2 |
| Wicht, F | 1 |
| Fisch, HU | 1 |
| Nelles, J | 1 |
| Raisin, J | 1 |
| Allemann, P | 1 |
| Preisig, R | 1 |
| Takada, A | 2 |
| Kobayashi, Y | 1 |
| Harcombe, AA | 1 |
| Ramsay, L | 1 |
| Kenna, JG | 1 |
| Koskinas, J | 1 |
| Why, HJ | 1 |
| Richardson, PJ | 1 |
| Weissberg, PL | 1 |
| Alexander, GJ | 1 |
| Svegliati-Baroni, G | 1 |
| Rosman, AS | 1 |
| Wickramasinghe, SN | 1 |
| Corridan, B | 1 |
| Hasan, R | 1 |
| Marjot, DH | 1 |
| Nicholls, RM | 1 |
| Fowles, LF | 1 |
| de Jersey, J | 4 |
| Wilce, PA | 3 |
| Sherman, DI | 1 |
| Williams, R | 1 |
| Lin, RC | 4 |
| Shahidi, S | 1 |
| Kelly, TJ | 1 |
| Lumeng, C | 1 |
| Lumeng, L | 2 |
| Paronetto, F | 1 |
| Albano, E | 3 |
| Parola, M | 1 |
| Comoglio, A | 1 |
| Dianzani, MU | 1 |
| Chandler, CJ | 1 |
| Munn, RJ | 1 |
| Panés, J | 1 |
| Caballería, J | 1 |
| Guitart, R | 1 |
| Parés, A | 1 |
| Soler, X | 1 |
| Rodamilans, M | 1 |
| Navasa, M | 1 |
| Parés, X | 1 |
| Bosch, J | 1 |
| Rodés, J | 1 |
| Teare, JP | 1 |
| Carmichael, AJ | 1 |
| Burnett, FR | 1 |
| Rake, MO | 1 |
| Zhang, H | 2 |
| Loney, LA | 1 |
| Potter, BJ | 2 |
| Paradis, V | 1 |
| Scoazec, JY | 1 |
| Köllinger, M | 1 |
| Holstege, A | 1 |
| Moreau, A | 1 |
| Feldmann, G | 1 |
| Bedossa, P | 1 |
| Löf, K | 1 |
| Lindros, K | 1 |
| Seppa, K | 1 |
| Fukunaga, T | 2 |
| Badger, T | 1 |
| Ronis, M | 1 |
| Sillanaukee, P | 1 |
| Li, CJ | 1 |
| Nanji, AA | 1 |
| Siakotos, AN | 1 |
| Kurose, I | 1 |
| Kato, S | 1 |
| Fillenwarth, MJ | 2 |
| Du, X | 1 |
| Nagata, N | 3 |
| Nishizaki, Y | 1 |
| Watanabe, N | 2 |
| Tsuda, M | 2 |
| Matsuzaki, S | 2 |
| Loguercio, C | 1 |
| Clot, P | 1 |
| Argenzio, F | 1 |
| Grella, A | 1 |
| De Girolamo, V | 1 |
| Delle Cave, M | 1 |
| Del Vecchio Bianco, C | 1 |
| Nardi, G | 1 |
| Clemens, DL | 1 |
| Casey, CA | 1 |
| Jayatilleke, A | 1 |
| Shaw, S | 3 |
| Koskinen, LK | 1 |
| Korpela, MM | 1 |
| Lahtela, JT | 1 |
| Laippala, PJ | 1 |
| Pikkarainen, PH | 1 |
| Koivula, TA | 1 |
| Pasanen, M | 2 |
| Iimuro , Y | 1 |
| Bradford, B | 1 |
| Tsukamoto, H | 1 |
| Jones, BL | 1 |
| Rolla, R | 1 |
| Vay, D | 1 |
| Mottaran, E | 1 |
| Parodi, M | 1 |
| Traverso, N | 1 |
| Aricó, S | 1 |
| Sartori, M | 1 |
| Bellomo, G | 1 |
| Viitala, K | 2 |
| Makkonen, K | 1 |
| Israel, Y | 4 |
| Lehtimäki, T | 1 |
| Jaakkola, O | 1 |
| Koivula, T | 1 |
| Blake, JE | 1 |
| Juvonen, RO | 1 |
| Gelboin, HV | 1 |
| Eriksson, CJ | 1 |
| Wyatt, TA | 1 |
| Yang, H | 1 |
| Wang, J | 1 |
| Huang, ZZ | 1 |
| Ou, X | 1 |
| Lu, SC | 1 |
| Kharbanda, KK | 1 |
| Todero, SL | 1 |
| Shubert, KA | 1 |
| Lindros, KO | 1 |
| Sipponen, P | 1 |
| Pikkarainen, P | 1 |
| Turunen, U | 1 |
| Day, CP | 1 |
| Bassendine, MF | 1 |
| Sidner, RA | 1 |
| Nicholls, R | 1 |
| Wilce, P | 1 |
| Lauterburg, BH | 1 |
| Brown, K | 1 |
| Shanley, BC | 2 |
| Behrens, UJ | 1 |
| Ma, XL | 1 |
| Hernández-Muñoz, R | 2 |
| Uppal, R | 1 |
| Mihas, AA | 1 |
| Tavassoli, M | 1 |
| Trudell, JR | 1 |
| Ardies, CM | 1 |
| Green, CE | 1 |
| Allen, K | 1 |
| Jennett, RB | 1 |
| Jayatilleke, E | 2 |
| Pratt, OE | 1 |
| Rooprai, HK | 1 |
| Shaw, GK | 1 |
| Thomson, AD | 1 |
| Kennedy, NP | 1 |
| Tipton, KF | 1 |
| Hurwitz, E | 1 |
| Arnon, R | 1 |
| Khanna, J | 1 |
| Orrego, H | 2 |
| Cobden, I | 1 |
| Matthewson, K | 2 |
| Carr, WP | 1 |
| Dick, WC | 1 |
| Record, CO | 2 |
| Szczepańska-Szewczyk, M | 1 |
| Szukalski, B | 1 |
| Puntarulo, S | 1 |
| Cederbaum, AI | 1 |
| Takase, S | 1 |
| Urashima, S | 1 |
| Yasuhara, M | 1 |
| Adachi, J | 1 |
| Mizoi, Y | 1 |
| Ogawa, Y | 1 |
| Imamichi, H | 1 |
| Kubota, S | 1 |
| Kawano, S | 1 |
| Matsumura, T | 1 |
| Inatomi, N | 1 |
| Mitchell, MC | 1 |
| Herlong, HF | 1 |
| Williams, AJ | 2 |
| Barry, RE | 4 |
| Eddleston, AL | 1 |
| Vento, S | 1 |
| Peters, TJ | 1 |
| Ward, RJ | 1 |
| Fleisher, JH | 1 |
| Lung, CC | 1 |
| Meinke, GC | 1 |
| Pinnas, JL | 1 |
| Thompson, RP | 1 |
| Mörikofer-Zwez, S | 1 |
| Al Mardini, H | 1 |
| Bartlett, K | 1 |
| Suwaki, H | 1 |
| Ihori, M | 1 |
| McGivan, JD | 1 |
50 reviews available for acetaldehyde and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
[Immune cells role and their new potential therapeutic targets in the pathogenesis of alcoholic liver disease].
Topics: Acetaldehyde; Adaptive Immunity; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Oxidative Stress | 2021 |
[Alcoholic liver disease: the roles of genetic-epigenetic factors and the effect of abstinence].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Epigenesis, Genetic; Fem | 2019 |
Pathogenesis of alcoholic liver disease: role of oxidative metabolism.
Topics: Acetaldehyde; Adaptive Immunity; Animals; Disease Progression; Ethanol; Humans; Immunity, Innate; Li | 2014 |
Chronic alcohol drinking: Liver and pancreatic cancer?
Topics: Acetaldehyde; Adaptive Immunity; Alcoholism; Carcinoma, Hepatocellular; Central Nervous System Depre | 2015 |
Role of Early Growth Response-1 in the Development of Alcohol-Induced Steatosis.
Topics: Acetaldehyde; Animals; Autophagy; Early Growth Response Protein 1; Gene Expression Regulation; Human | 2017 |
Role of alcohol in liver carcinogenesis.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; | 2009 |
Endotoxemia and gut barrier dysfunction in alcoholic liver disease.
Topics: Acetaldehyde; Adherens Junctions; Animals; Endotoxemia; Ethanol; Humans; Intestinal Mucosa; Intestin | 2009 |
Post-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Asian People; | 2011 |
Mechanisms of alcohol liver damage: aldehydes, scavenger receptors, and autoimmunity.
Topics: Acetaldehyde; Aldehydes; Animals; Apoptosis; Autoimmune Diseases; Autoimmunity; CD4-Positive T-Lymph | 2004 |
[Biochemical basic of alcoholic liver injury].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Animals; Cytochrome P-450 CYP2E1; Ethanol; Fatty Li | 2006 |
Liver disorders in alcoholism.
Topics: Acetaldehyde; Animals; Carcinoma, Hepatocellular; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoho | 1984 |
[Alcohol and the liver].
Topics: Acetaldehyde; Carbohydrate Metabolism; Enzyme Induction; Fatty Liver; gamma-Glutamyltransferase; Hep | 1981 |
Alcohol, protein nutrition, and liver injury.
Topics: Acetaldehyde; Animals; Collagen; Cysteine; Dietary Fats; Dietary Proteins; Fatty Acids; Fatty Liver, | 1983 |
Alcohol, liver injury and protein metabolism.
Topics: Acetaldehyde; Alcoholism; Amino Acids; Carbohydrate Metabolism; Collagen; Dietary Proteins; Ethanol; | 1980 |
Metabolic effects of ethanol on the liver and other digestive organs.
Topics: Acetaldehyde; Amino Acids; Aminobutyrates; Biotransformation; Carcinogens; Digestive System; Enzyme | 1981 |
Effects of alcohol on hepatic transport of proteins.
Topics: Acetaldehyde; Albumins; Animals; Biological Transport; Ethanol; Humans; Liver; Liver Diseases, Alcoh | 1982 |
Effects of ethanol on protein synthesis and secretion.
Topics: Acetaldehyde; Alcoholism; Animals; Dose-Response Relationship, Drug; Ethanol; Humans; Liver; Liver C | 1980 |
Genotypes of ALDH2 related to liver and pulmonary diseases and other genetic factors related to alcoholic liver disease.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Asthma; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Syste | 1994 |
Liver damage: mechanisms and management.
Topics: Acetaldehyde; Ethanol; Female; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; | 1994 |
Biochemical factors in alcoholic liver disease.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Body Weight; Catalase; Ethanol; Humans; Liver; Live | 1993 |
Immunologic reactions in alcoholic liver disease.
Topics: Acetaldehyde; Antibodies; Cytokines; Hepacivirus; Hepatitis B virus; HLA Antigens; Humans; Immunoglo | 1993 |
Role of oxidative stress and antioxidant therapy in alcoholic and nonalcoholic liver diseases.
Topics: Acetaldehyde; Animals; Antioxidants; Humans; Lipid Peroxidation; Liver Diseases; Liver Diseases, Alc | 1997 |
Susceptibility to alcohol-related liver injury.
Topics: Acetaldehyde; Age Factors; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Catalase; Cytokin | 1994 |
[Current aspects of alcohol-induced liver damage].
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Cytochrome P-450 Enzyme System; Fatty Liver; Female; Hepatitis | 1995 |
Pathogenesis of alcoholic liver disease with particular emphasis on oxidative stress.
Topics: Acetaldehyde; Animals; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Oxidative Stress; Oxidored | 1997 |
The role of acetaldehyde in the actions of alcohol (update 2000).
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol-Induced Disorders; Alcoholic Intoxica | 2001 |
The chemistry and biological effects of malondialdehyde-acetaldehyde adducts.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Central Nervou | 2001 |
Distribution of ethanol-induced protein adducts in vivo: relationship to tissue injury.
Topics: Acetaldehyde; Animals; Ethanol; Free Radicals; Humans; Immunity; Lipid Peroxidation; Liver Diseases, | 2001 |
Genetic predisposition to alcoholic liver disease.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Ethanol; Female; Genes; Genotype; Humans; Liver; Liver Disease | 1992 |
Modification of proteins and other biological molecules by acetaldehyde: adduct structure and functional significance.
Topics: Acetaldehyde; Animals; Ethanol; Humans; Immunochemistry; In Vitro Techniques; Liver; Liver Diseases, | 1992 |
[Pathogenesis of alcoholic liver disease].
Topics: Acetaldehyde; Alcoholism; Environment; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Nutritiona | 1992 |
Alcohol, liver, and nutrition.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Collagen; Ethanol; Hormones; Humans; Liver; Liver C | 1991 |
Contribution of exogenous ethanol and endogenous substrates to acetaldehyde-adduct formation in liver injury.
Topics: Acetaldehyde; Alcoholism; Animals; Carbon Tetrachloride Poisoning; Erythrocytes; Ethanol; Humans; Li | 1991 |
Biochemical mechanisms of alcohol-induced hepatic injury.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Animals; Drug Tolerance; Ethanol; Humans; Liver; Li | 1991 |
Effects of acetaldehyde on hepatic proteins.
Topics: Acetaldehyde; Animals; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Protein Binding; Proteins | 1990 |
Mechanism of ethanol induced hepatic injury.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Endotoxins; Ethanol; Humans; Liver Cirrhosis, Alcoholi | 1990 |
The genesis of alcoholic brain tissue injury.
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Brain Damage, Chronic; Ethanol; Free Radicals; Humans; Liv | 1990 |
Ethanol metabolism and alcoholic liver disease.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Ethanol; Humans; Lipid Peroxidation; Liver; Liver Dise | 1990 |
Alcohol and the liver: metabolism of ethanol, metabolic effects and pathogenesis of injury.
Topics: Acetaldehyde; Acetates; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Blood G | 1985 |
Immune responses to alcohol metabolites: pathogenic and diagnostic implications.
Topics: Acetaldehyde; Antibody Formation; Epitopes; Ethanol; Humans; Immunity, Cellular; Liver Diseases, Alc | 1988 |
[Biochemical aspects of alcoholism. IV. Alcohol-induced diseases of the liver].
Topics: Acetaldehyde; Alcoholism; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Humans; Liver; Live | 1989 |
Alcohol and nutrition: caloric value, bioenergetics, and relationship to liver damage.
Topics: Acetaldehyde; Adenosine Triphosphate; Adolescent; Adult; Aged; Alcohol Dehydrogenase; Alcohol Drinki | 1986 |
Metabolism of ethanol and its consequences for the liver and gastrointestinal tract.
Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Gastrointestinal Diseases; Humans; Liver Diseases, Alcoh | 1988 |
Relevance of immune mediated mechanisms in progressive alcoholic liver injury.
Topics: Acetaldehyde; Animals; Antibody Formation; Hepatitis B; Humans; Immunity, Cellular; Liver Diseases, | 1988 |
Role of acetaldehyde in the pathogenesis of alcoholic liver disease.
Topics: Acetaldehyde; Alcoholism; Free Radicals; Humans; Liver Diseases, Alcoholic | 1988 |
Role of acetaldehyde in the pathogenesis of alcoholic liver disease.
Topics: Acetaldehyde; Alcoholism; Humans; Liver; Liver Diseases, Alcoholic | 1988 |
Measuring the damage--ethanol and the liver.
Topics: Acetaldehyde; Aldehyde Oxidoreductases; Ethanol; Female; Gastric Emptying; Humans; Intestinal Absorp | 1986 |
Alcohol and alcohol problems research 2. Japan.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Female; Fetal Alcohol Spectrum D | 1985 |
[Alcoholic liver injuries].
Topics: Acetaldehyde; Animals; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Humans; Liver; Liver D | 1985 |
Covalent binding of acetaldehyde to hepatic proteins: role in alcoholic liver injury.
Topics: Acetaldehyde; Animals; Ascorbic Acid; Ethanol; In Vitro Techniques; Liver; Liver Diseases, Alcoholic | 1985 |
1 trial available for acetaldehyde and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Effect of acetaldehyde and acetylsalicylic acid on HbA1c chromatography in the FPLC method with Mono S cation exchanger.
Topics: Acetaldehyde; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cation Exchange Resins; Chrom | 1998 |
98 other studies available for acetaldehyde and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease.
Topics: Acetaldehyde; Adult; Alcoholism; Biomarkers; Fatty Liver; Humans; Immunoglobulin A; Immunoglobulin G | 2022 |
A novel reactive aldehyde species inhibitor prevents the deleterious effects of ethanol in an animal model of alcoholic liver disease.
Topics: Acetaldehyde; Aldehydes; Animals; Disease Models, Animal; Ethanol; Liver Diseases, Alcoholic; Malond | 2022 |
A novel reactive aldehyde species inhibitor prevents the deleterious effects of ethanol in an animal model of alcoholic liver disease.
Topics: Acetaldehyde; Aldehydes; Animals; Disease Models, Animal; Ethanol; Liver Diseases, Alcoholic; Malond | 2022 |
A novel reactive aldehyde species inhibitor prevents the deleterious effects of ethanol in an animal model of alcoholic liver disease.
Topics: Acetaldehyde; Aldehydes; Animals; Disease Models, Animal; Ethanol; Liver Diseases, Alcoholic; Malond | 2022 |
A novel reactive aldehyde species inhibitor prevents the deleterious effects of ethanol in an animal model of alcoholic liver disease.
Topics: Acetaldehyde; Aldehydes; Animals; Disease Models, Animal; Ethanol; Liver Diseases, Alcoholic; Malond | 2022 |
Alcohol-induced tubulin post-translational modifications directly alter hepatic protein trafficking.
Topics: Acetaldehyde; Animals; Ethanol; Humans; Liver Diseases, Alcoholic; Mice; Protein Processing, Post-Tr | 2023 |
Hepatic progesterone receptor membrane component 1 attenuates ethanol-induced liver injury by reducing acetaldehyde production and oxidative stress.
Topics: Acetaldehyde; Animals; Chemical and Drug Induced Liver Injury, Chronic; Ethanol; Humans; Liver; Live | 2023 |
Mulberry leaves extract ameliorates alcohol-induced liver damages through reduction of acetaldehyde toxicity and inhibition of apoptosis caused by oxidative stress signals.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Enzy | 2021 |
CD39-mediated ATP-adenosine signalling promotes hepatic stellate cell activation and alcoholic liver disease.
Topics: 5'-Nucleotidase; Acetaldehyde; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Ca | 2021 |
NOX4 Regulates CCR2 and CCL2 mRNA Stability in Alcoholic Liver Disease.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Cell Nucleus; Cells, Cultured; Chemokine CCL2; ELAV-Like Pr | 2017 |
Mitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: A molecular mechanism of protection against alcoholic liver disease.
Topics: Acetaldehyde; Aldehyde Dehydrogenase, Mitochondrial; Animals; Cell Line; Liver Diseases, Alcoholic; | 2018 |
Liver tissue metabolically transformed by alcohol induces immune recognition of liver self-proteins but not in vivo inflammation.
Topics: Acetaldehyde; Adoptive Transfer; Animals; Autoimmunity; Cell Movement; Cells, Cultured; Disease Mode | 2018 |
Protective Effects of Facilitated Removal of Blood Alcohol and Acetaldehyde Against Liver Injury in Animal Models Fed Alcohol and Anti-HIV Drugs.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Animals; Anti-HIV Agents; Catalase; D | 2019 |
RNA interference against discoidin domain receptor 2 ameliorates alcoholic liver disease in rats.
Topics: Acetaldehyde; Animals; Apoptosis; Cell Line; Cell Proliferation; Collagen Type I; Discoidin Domain R | 2013 |
Protective effect of cordycepin-enriched Cordyceps militaris on alcoholic hepatotoxicity in Sprague-Dawley rats.
Topics: Acetaldehyde; Alanine Transaminase; Alcohol Drinking; Alkaline Phosphatase; Animals; Aspartate Amino | 2013 |
Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease.
Topics: Acetaldehyde; Aldehydes; Animals; Cells, Cultured; Ethanol; Glutathione; Glycation End Products, Adv | 2013 |
Effects of Beverages on Alcohol Metabolism: Potential Health Benefits and Harmful Impacts.
Topics: Acetaldehyde; Alanine Transaminase; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Aspartat | 2016 |
Purinergic P2X7 receptor mediates acetaldehyde-induced hepatic stellate cells activation via PKC-dependent GSK3β pathway.
Topics: Acetaldehyde; Adenosine Triphosphate; Animals; Cells, Cultured; Fibrosis; Glycogen Synthase Kinase 3 | 2017 |
Potential relationship between hepatobiliary osteopontin and peroxisome proliferator-activated receptor alpha expression following ethanol-associated hepatic injury in vivo and in vitro.
Topics: Acetaldehyde; Animals; Bezafibrate; Bile Ducts; Cell Line, Tumor; Disease Models, Animal; Epithelial | 2008 |
Acetaldehyde-induced mitochondrial dysfunction sensitizes hepatocytes to oxidative damage.
Topics: Acetaldehyde; Adenosine Triphosphate; Animals; Antimycin A; Cell Respiration; Cell Survival; Drug Sy | 2009 |
Role of aldehyde dehydrogenase-2 in alcoholic liver disease.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Anima | 2009 |
Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-alpha production in cultured macrophage cell lines.
Topics: Acetaldehyde; Acetates; Acetylation; Adiponectin; Animals; Benzamides; Cell Line; Enzyme Inhibitors; | 2009 |
Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices.
Topics: Acetaldehyde; Actins; Animals; Brassica; Cell Survival; Collagen; Ethanol; Hepatic Stellate Cells; I | 2010 |
Hepatoprotective effects on alcoholic liver disease of fermented silkworms with Bacillus subtilis and Aspergillus kawachii.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Animals; Antioxidants; Aspartate Amin | 2012 |
Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices.
Topics: Acetaldehyde; Animals; Ethanol; Hepatic Stellate Cells; Indoles; Liver; Liver Diseases, Alcoholic; M | 2012 |
Experimental studies on the relationship between immune responses and liver damage induced by ethanol after immunization with homologous acetaldehyde adducts.
Topics: Acetaldehyde; Animals; Autoimmune Diseases; Immunization; Liver; Liver Diseases, Alcoholic; Liver Fu | 2002 |
Chronic ethanol consumption impairs receptor-mediated endocytosis of MAA-modified albumin by liver endothelial cells.
Topics: Acetaldehyde; Albumins; Alcohol Drinking; Animals; Binding Sites; Central Nervous System Depressants | 2003 |
Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage.
Topics: Acetaldehyde; Animals; Apoptosis; Cell Division; Central Nervous System Depressants; Ethanol; Hepato | 2004 |
Immune Responses to Ethanol Metabolites and Cytokine Profiles Differentiate Alcoholics with or without Liver Disease.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Antibodies, Anticardiolipin; Autoantigens; Autoimmunity; Biom | 2005 |
Recent advances in alcohol-induced adduct formation.
Topics: Acetaldehyde; Alcohol-Related Disorders; Alcoholism; Animals; Cardiomyopathy, Alcoholic; DNA Adducts | 2005 |
From alcohol toxicity to treatment.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol-Related Disorders; Alcoholism; Alleles; Cholestasis, In | 2005 |
Microtubules are more stable and more highly acetylated in ethanol-treated hepatic cells.
Topics: Acetaldehyde; Acetylation; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Central Nervous Sys | 2006 |
Acetaldehyde inhibits PPARgamma via H2O2-mediated c-Abl activation in human hepatic stellate cells.
Topics: Acetaldehyde; Animals; Cells, Cultured; Central Nervous System Depressants; Collagen; Ethanol; Extra | 2006 |
Acetaldehyde-induced barrier disruption and paracellular permeability in Caco-2 cell monolayer.
Topics: Acetaldehyde; Caco-2 Cells; Cell Culture Techniques; Cell Survival; Electric Impedance; Endotoxins; | 2008 |
Formation and immunological properties of aldehyde-derived protein adducts following alcohol consumption.
Topics: Acetaldehyde; Alcohol Drinking; Aldehydes; Animals; Antibodies; Antibodies, Monoclonal; Antibody Spe | 2008 |
Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Avena; Bacterial Translocation; Burns; Endotoxins; ErbB Rec | 2008 |
[Alcoholic liver diseases. Biochemical and clinical studies on pathogenesis and early diagnosis].
Topics: Acetaldehyde; Alcohol Oxidoreductases; Biochemical Phenomena; Biochemistry; Catalase; Chlorpromazine | 1980 |
Could superoxide cause cirrhosis?
Topics: Acetaldehyde; Humans; Lipid Metabolism; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic | 1982 |
Aldehyde dehydrogenase and alcoholism.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Cytosol; Humans; Liver; Liver Diseases, Alcoholi | 1983 |
Lipid peroxidation in alcoholic myopathy and cardiomyopathy.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Cardiomyopathy, Alcoholic; Catalase; Eth | 1984 |
Alcohol-induced liver injury. The role of oxygen.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Humans; L-Lactate | 1984 |
[Metabolic aspects of alcoholic liver damage: 1984/5 update. 1. Epidemiology and alcohol metabolism].
Topics: Acetaldehyde; Acidosis; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Collagen; | 1984 |
Low Km ALDH isozyme and alcoholic liver injury.
Topics: Acetaldehyde; Adolescent; Adult; Aged; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Oxidoreduc | 1983 |
Effect of ethanol on hepatic secretory proteins.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Animals; Blood Proteins; Ethanol; Glycoproteins; H | 1984 |
Alcohol, protein metabolism, and liver injury.
Topics: Acetaldehyde; Amino Acids; Aminobutyrates; Animals; Collagen; Dietary Proteins; Ethanol; Fatty Acids | 1980 |
Mechanism of the protective action of thiol compounds in ethanol-induced liver injury.
Topics: Acetaldehyde; Animals; Cysteine; Ethanol; Lipid Metabolism; Liver Diseases, Alcoholic; Male; Rats; R | 1983 |
[Acetaldehyde-induced leukocyte migration inhibition in alcoholic liver diseases].
Topics: Acetaldehyde; Cell Migration Inhibition; Hepatitis, Alcoholic; Humans; Leukocytes; Liver Cirrhosis, | 1982 |
[Immune response against protein epitopes modified with acetaldehyde and its clinical significance in alcoholic liver diseases].
Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Epitopes; Female; Guinea Pigs; Humans; Liver Diseases | 1993 |
Immune mechanisms of alcohol-induced liver disease.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Antibody Formation; Antigens; Epitopes; Humans; Immune Syst | 1995 |
Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease.
Topics: Acetaldehyde; Aldehydes; Animals; Guinea Pigs; Immunohistochemistry; Lipid Peroxidation; Liver; Live | 1995 |
Divergence of ethanol and acetaldehyde kinetics and of the disulfiram-alcohol reaction between subjects with and without alcoholic liver disease.
Topics: Acetaldehyde; Adult; Aged; Combined Modality Therapy; Disulfiram; Dose-Response Relationship, Drug; | 1995 |
Circulating antibodies to cardiac protein-acetaldehyde adducts in alcoholic heart muscle disease.
Topics: Acetaldehyde; Adult; Aged; Antibodies; Biomarkers; Blotting, Western; Cardiomyopathy, Alcoholic; Cyt | 1995 |
Collagen-acetaldehyde adducts in alcoholic and nonalcoholic liver diseases.
Topics: Acetaldehyde; Adult; Aged; Analysis of Variance; Animals; Aspartate Aminotransferases; Collagen; gam | 1994 |
Correlations between acetaldehyde-modified haemoglobin, carbohydrate-deficient transferrin (CDT) and haematological abnormalities in chronic alcoholism.
Topics: Acetaldehyde; Adult; Alcoholism; Bilirubin; Blood Cell Count; Enzymes; Erythrocyte Indices; Female; | 1994 |
Distribution and turnover of acetaldehyde-modified proteins in liver and blood of ethanol-fed rats.
Topics: Acetaldehyde; Alcoholism; Animals; Blood Proteins; Cytosol; Enzyme-Linked Immunosorbent Assay; Ethan | 1994 |
Measurement of hemoglobin-acetaldehyde adduct in alcoholic patients.
Topics: Acetaldehyde; Alcoholism; Enzyme-Linked Immunosorbent Assay; Female; Hemoglobins; Humans; Liver Dise | 1993 |
Evidence for the covalent binding of hydroxyethyl radicals to rat liver microsomal proteins.
Topics: Acetaldehyde; Animals; Binding Sites; Ethanol; Free Radicals; Hydroxyl Radical; Liver Diseases, Alco | 1993 |
Centrilobular distribution of acetaldehyde and collagen in the ethanol-fed micropig.
Topics: Acetaldehyde; Animals; Collagen; Disease Models, Animal; Ethanol; Iron; Liver; Liver Diseases, Alcoh | 1993 |
Determinants of ethanol and acetaldehyde metabolism in chronic alcoholics.
Topics: Acetaldehyde; Adult; Aged; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Femal | 1993 |
Detection of antibodies to acetaldehyde-albumin conjugates in alcoholic liver disease.
Topics: Acetaldehyde; Autoantibodies; Autoantigens; Blood Proteins; Enzyme-Linked Immunosorbent Assay; Fatty | 1993 |
Effect of chronic alcohol feeding on hepatic iron status and ferritin uptake by rat hepatocytes.
Topics: Acetaldehyde; Alcoholism; Animals; Cells, Cultured; Ferritins; Iron; Liver; Liver Diseases, Alcoholi | 1993 |
Cellular and subcellular localization of acetaldehyde-protein adducts in liver biopsies from alcoholic patients.
Topics: Acetaldehyde; Animals; Biopsy; Cells, Cultured; Cytosol; Endoplasmic Reticulum; Humans; Immunohistoc | 1996 |
The effect of ethanol or hepatotoxin exposure on rat transferrin desialylation.
Topics: Acetaldehyde; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethan | 1996 |
Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease.
Topics: Acetaldehyde; Aldehydes; Animals; Antibodies; Corn Oil; Dietary Fats; Fatty Liver; Fish Oils; Humans | 1997 |
Cytotoxic effect of 7alpha-hydroxy-4-cholesten-3-one on HepG2 cells: hypothetical role of acetaldehyde-modified delta4-3-ketosteroid-5beta-reductase (the 37-kd-liver protein) in the pathogenesis of alcoholic liver injury in the rat.
Topics: Acetaldehyde; Animals; Cell Death; Cell Line; Cell Nucleus; Cholestenones; Culture Media; DNA Fragme | 1998 |
An enzyme immune assay for serum anti-acetaldehyde adduct antibody using low-density lipoprotein adduct and its significance in alcoholic liver injury.
Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Animals; Antibodies; Cattle; Female; Humans; Immunoenz | 1998 |
Free radicals and not acetaldehyde influence the circulating levels of glutathione after acute or chronic alcohol abuse: in vivo and in vitro studies.
Topics: Acetaldehyde; Acute Disease; Adult; Alcoholic Intoxication; Alcoholism; Chronic Disease; Erythrocyte | 1997 |
Ethanol oxidation mediates impaired hepatic receptor-mediated enocytosis.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Asialoglycoprotein Receptor; Cell Line, Transformed; E | 1998 |
Stimulation of monocyte interleukin-8 by lipid peroxidation products: a mechanism for alcohol-induced liver injury.
Topics: Acetaldehyde; alpha-Linolenic Acid; Arachidonic Acid; Ethanol; Humans; Hydrocortisone; Interleukin-8 | 1998 |
Early alcoholic liver injury: formation of protein adducts with acetaldehyde and lipid peroxidation products, and expression of CYP2E1 and CYP3A.
Topics: Acetaldehyde; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3 | 1998 |
Relationship between serum levels of anti-low-density lipoprotein-acetaldehyde-adduct antibody and aldehyde dehydrogenase 2 heterozygotes in patients with alcoholic liver injury.
Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitoch | 1999 |
Conversion of acetaldehyde-protein adduct epitopes from a nonreduced to a reduced phenotype by antigen processing cells.
Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Antibody Formation; Antigen Presentation; Antigen-Pre | 1999 |
Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease.
Topics: Acetaldehyde; Adult; Aged; Antibodies; Antibody Specificity; Enzyme-Linked Immunosorbent Assay; Epit | 2000 |
Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers.
Topics: Acetaldehyde; Alcohol Drinking; Analysis of Variance; Autoantibodies; Autoimmunity; Chi-Square Distr | 2000 |
Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases.
Topics: Acetaldehyde; Adipose Tissue; Adult; Aldehydes; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2 | 2000 |
Cloning and characterization of the 5'-flanking region of the rat glutamate-cysteine ligase catalytic subunit.
Topics: 5' Untranslated Regions; Acetaldehyde; Animals; Base Sequence; Catalysis; Cell Line; Cloning, Molecu | 2001 |
Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells.
Topics: Acetaldehyde; Animals; Cells, Cultured; Chemokine CCL2; Chemokine CXCL2; Chemokines; Dose-Response R | 2001 |
Alcoholic liver damage is provoked by 4-methylpyrazole, which prolongs the influence of ethanol but reduces acetaldehyde levels.
Topics: Acetaldehyde; Animals; Drug Interactions; Ethanol; Liver; Liver Diseases, Alcoholic; Male; Pyrazoles | 1979 |
Immune responses to acetaldehyde-protein adducts: role in alcoholic liver disease.
Topics: Acetaldehyde; Humans; Immunoglobulin A; Liver Diseases, Alcoholic; Proteins | 1992 |
Localization of protein-acetaldehyde adducts on cell surface of hepatocytes by flow cytometry.
Topics: Acetaldehyde; Animals; Cytosol; Flow Cytometry; Liver; Liver Diseases, Alcoholic; Male; Membrane Pro | 1992 |
The effect of ethanol metabolism on ferritin uptake by freshly isolated rat hepatocytes: is acetaldehyde responsible for this alteration?
Topics: Acetaldehyde; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Ethanol; Ferritins; Hemosi | 1992 |
Alcohol hepatotoxicity: a genotypic predisposition?
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Disease Susceptibility; Female; Heterozygote; Humans; Liver Di | 1992 |
Antibodies against acetaldehyde-modified epitopes: an elevated IgA response in alcoholics.
Topics: Acetaldehyde; Alcoholism; Epitopes; Hemoglobins; Humans; Immunoglobulin A; Liver; Liver Diseases; Li | 1991 |
The effect of ethanol on the uptake, binding, and desialylation of transferrin by rat liver endothelium: implications in the pathogenesis of alcohol-associated hepatic siderosis.
Topics: Acetaldehyde; Acetates; Animals; Biological Transport; Endothelium; Ethanol; In Vitro Techniques; Ir | 1991 |
Binding of anti-acetaldehyde IgG antibodies to hepatocytes with an acetaldehyde-phosphatidylethanolamine adduct on their surface.
Topics: Acetaldehyde; Animals; Cell Membrane; Cross Reactions; Immunoglobulin G; Liver; Liver Diseases, Alco | 1991 |
Ethanol-induced iron mobilization: role of acetaldehyde-aldehyde oxidase generated superoxide.
Topics: Acetaldehyde; Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Colorimetry; Ethanol; Ferritins; | 1990 |
Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies, Monoclonal; Antibody Formation; Blood Proteins; Epito | 1986 |
Antibodies against acetaldehyde- modified epitopes: a new perspective.
Topics: Acetaldehyde; Antibodies; Antibody Specificity; Antigen-Antibody Complex; Epitopes; Humans; Liver Di | 1987 |
Effect of ethanol challenge on serum glycoproteins in alcoholic and non-alcoholic liver disease.
Topics: Acetaldehyde; alpha-Macroglobulins; Ethanol; Glycoproteins; Haptoglobins; Humans; Liver Cirrhosis; L | 1987 |
Ethanol induces the production of antibodies to acetaldehyde-modified epitopes in rats.
Topics: Acetaldehyde; Alcoholism; Animals; Autoantibodies; Autoantigens; Carrier Proteins; Epitopes; Ethanol | 1989 |
Chemiluminescence from acetaldehyde oxidation by xanthine oxidase involves generation of and interactions with hydroxyl radicals.
Topics: Acetaldehyde; Catalase; Humans; Hydroxides; Hydroxyl Radical; Liver; Liver Diseases, Alcoholic; Lumi | 1989 |
Studies on aldehyde dehydrogenase type V-A isozymes in liver disease.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Humans; Isoenzymes; Liver Cirrhosis, Alcohol | 1989 |
Comparative study on ethanol elimination and blood acetaldehyde between alcoholics and control subjects.
Topics: Acetaldehyde; Adult; Aged; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Humans; Liver Diseases, Alco | 1989 |
Impaired oxygen utilization. A new mechanism for the hepatotoxicity of ethanol in sub-human primates.
Topics: Acetaldehyde; Animals; Ethanol; Indocyanine Green; Liver; Liver Diseases, Alcoholic; Oxidation-Reduc | 1989 |
[Metabolic aspects of alcoholic liver damage: 1984/1985 update. 2: Microsomal enzyme induction and hypermetabolism].
Topics: Acetaldehyde; Alcohol Oxidoreductases; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Enzyme | 1985 |
Superoxide anion production and degranulation of rat neutrophils in response to acetaldehyde-altered liver cell membranes.
Topics: Acetaldehyde; Animals; Cell Membrane; Female; Free Radicals; Liver; Liver Diseases, Alcoholic; Neutr | 1986 |
Acetaldehyde-mediated hepatic lipid peroxidation: role of superoxide and ferritin.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Ethanol; Ferritins; In Vitro Techniques; Lipid Peroxid | 1987 |
Acetaldehyde-albumin adduct formation: possible relevance to an immunologic mechanism in alcoholism.
Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Enzyme-Linked Immunosorbent Assay; Haptens; H | 1988 |
[Alcohol: biochemistry and health].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Humans; Liver; Liv | 1987 |
Impaired acetaldehyde metabolism in patients with non-alcoholic liver disorders.
Topics: Acetaldehyde; Adult; Aged; Aldehyde Dehydrogenase; Chromatography, Gas; Cytosol; Ethanol; Female; Hu | 1986 |
Acetaldehyde alone may initiate hepatocellular damage in acute alcoholic liver disease.
Topics: Acetaldehyde; Cell Membrane; Complement Activation; Complement C3; Humans; Liver; Liver Diseases, Al | 1985 |