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acetaldehyde and Liver Diseases, Alcoholic

acetaldehyde has been researched along with Liver Diseases, Alcoholic in 149 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.

Research Excerpts

ExcerptRelevanceReference
"In spite of continuing alcohol abuse, only a fraction of all alcoholics will develop alcoholic hepatitis and eventually cirrhosis."2.38[Pathogenesis of alcoholic liver disease]. ( Lauterburg, BH, 1992)
"Acetaldehyde was found to be transported in the blood mainly bound reversibly to 2 components of the red blood cells (RBC): a) hemoglobin, which provides binding of a high affinity, but low capacity, and b) a non-protein component (presumably cysteine), which has a lower affinity but a higher capacity."2.38Contribution of exogenous ethanol and endogenous substrates to acetaldehyde-adduct formation in liver injury. ( Baraona, E; Behrens, UJ; Hernández-Muñoz, R; Lieber, CS; Ma, XL; Uppal, R, 1991)
"Acetaldehyde also promotes glutathione depletion, free-radical mediated toxicity, lipid peroxidation and hepatic collagen synthesis."2.38Biochemical mechanisms of alcohol-induced hepatic injury. ( Lieber, CS, 1991)
"1."2.38The genesis of alcoholic brain tissue injury. ( Pratt, OE; Rooprai, HK; Shaw, GK; Thomson, AD, 1990)
"Acetaldehyde is a toxic material produced when alcohol is metabolized through some enzymes, and it causes endoplasmic reticulum (ER) stress, mitochondrial dysfunction, and tissue injury."1.91Hepatic progesterone receptor membrane component 1 attenuates ethanol-induced liver injury by reducing acetaldehyde production and oxidative stress. ( Baek, IJ; Hong, EJ; Jo, SL; Ko, JW; Kwun, HJ; Shin, HJ, 2023)
"GGT indicates Alcohol Abuse only in background of normal LFT."1.72Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease. ( BhatB, NM, 2022)
"24% were in steatosis,32% were in steatohepatitis, while 44% were in cirrhosis."1.72Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease. ( BhatB, NM, 2022)
" Severe fatty degeneration was observed during chronic administration of ethanol increasing from 4-8 weeks."1.39Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease. ( Arisawa, T; Fukumura, A; George, J; Hayashi, N; Takeuchi, M; Toshikuni, N; Tsutsumi, M, 2013)
"Unlike the action of alcohol treatment on fatty liver, BFSP administration attenuated lipid droplet accumulation in hepatocytes."1.38Hepatoprotective effects on alcoholic liver disease of fermented silkworms with Bacillus subtilis and Aspergillus kawachii. ( Cha, JY; Cho, YS; Kim, YS; Moon, HI, 2012)
"Acetaldehyde treatment of H4IIE cells led to a time- and dose-dependent increase in GCLC mRNA levels, binding of NF-kappaB and AP-1 to the GCLC promoter, and luciferase activity driven by the GCLC promoter fragment containing these binding sites."1.31Cloning and characterization of the 5'-flanking region of the rat glutamate-cysteine ligase catalytic subunit. ( Huang, ZZ; Lu, SC; Ou, X; Wang, J; Yang, H, 2001)
"No acetaldehyde adduct was detected in the control rats that were pair-fed with isocaloric amounts of dextrose."1.30Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease. ( Li, CJ; Lin, RC; Nanji, AA; Siakotos, AN, 1997)
"An acetaldehyde (AcH) adduct was prepared using rabbit low-density lipoprotein as carrier proteins."1.30An enzyme immune assay for serum anti-acetaldehyde adduct antibody using low-density lipoprotein adduct and its significance in alcoholic liver injury. ( Matsuzaki, S; Nagata, N; Nishizaki, Y; Tsuda, M; Watanabe, N, 1998)
"Acetaldehyde adducts were found by immunofluorescence in the centrilobular region and were focused in perivenous zone 3 of all ethanol-fed animals."1.29Centrilobular distribution of acetaldehyde and collagen in the ethanol-fed micropig. ( Chandler, CJ; Halsted, CH; Munn, RJ; Niemelä, O; Parkkila, S; Ruebner, B; Villanueva, J, 1993)
"Alcohol abuse is known to cause disturbances to iron homeostasis in man and is associated with elevated serum ferritin levels."1.29Effect of chronic alcohol feeding on hepatic iron status and ferritin uptake by rat hepatocytes. ( Loney, LA; Potter, BJ; Zhang, H, 1993)

Research

Studies (149)

TimeframeStudies, this research(%)All Research%
pre-199046 (30.87)18.7374
1990's52 (34.90)18.2507
2000's27 (18.12)29.6817
2010's17 (11.41)24.3611
2020's7 (4.70)2.80

Authors

AuthorsStudies
BhatB, NM1
Duryee, MJ6
Aripova, N3
Hunter, CD4
Ruskamp, RJ3
Tessin, MR3
Works, DR3
Mikuls, TR4
Thiele, GM11
Adhikari, R1
Mitra, R1
Bennett, RG1
McVicker, BL1
Tuma, PL2
Jo, SL1
Baek, IJ1
Ko, JW1
Kwun, HJ1
Shin, HJ1
Hong, EJ1
Liang, HW1
Yang, TY1
Teng, CS1
Lee, YJ1
Yu, MH1
Lee, HJ1
Hsu, LS1
Wang, CJ1
Shuai, C1
Xia, GQ1
Yuan, F1
Wang, S2
Lv, XW1
Zhang, FY1
Gao, YH1
Sasaki, Y1
Dehnad, A1
Fish, S1
Sato, A1
Jiang, J1
Tian, J1
Schröder, K1
Brandes, R1
Török, NJ1
Hao, L1
Sun, Q1
Zhong, W1
Zhang, W1
Sun, X2
Zhou, Z1
Wiese, BM1
Bowman, JR1
Vanlandingham, JD1
Klassen, LW10
Thiele, GE1
Anderson, DR1
Han, H1
He, Y1
Johnson, H1
Mishra, P1
Lee, H1
Ji, C1
Pár, A1
Pár, G1
Luo, Z1
Liu, H1
Guo, R1
Cui, R1
Ma, X1
Yan, M1
Cha, JY2
Ahn, HY1
Cho, YS2
Je, JY1
Hayashi, N1
George, J1
Takeuchi, M1
Fukumura, A1
Toshikuni, N1
Arisawa, T1
Tsutsumi, M2
Ceni, E2
Mello, T2
Galli, A2
Zakhari, S1
Thomes, PG1
Donohue, TM1
Wang, F1
Zhang, YJ1
Zhou, Y1
Li, Y1
Zhou, T1
Zheng, J1
Zhang, JJ1
Li, S1
Xu, DP1
Li, HB1
Wu, X1
Wang, Y1
Xu, R1
Lv, X1
Lee, JH1
Banerjee, A1
Ueno, Y1
Ramaiah, SK1
Farfán Labonne, BE1
Gutiérrez, M1
Gómez-Quiroz, LE1
Konigsberg Fainstein, M1
Bucio, L1
Souza, V1
Flores, O1
Ortíz, V1
Hernández, E1
Kershenobich, D1
Gutiérrez-Ruíz, MC1
Youtz, DJ1
Wold, LE1
Shen, Z1
Ajmo, JM1
Rogers, CQ1
Liang, X1
Le, L1
Murr, MM1
Peng, Y1
You, M1
McKillop, IH1
Schrum, LW1
Rao, R2
Guo, Y2
Wu, XQ2
Zhang, C2
Liao, ZX2
Wu, Y1
Xia, ZY1
Wang, H2
Song, BJ1
Abdelmegeed, MA1
Yoo, SH1
Kim, BJ1
Jo, SA1
Jo, I1
Moon, KH1
Kim, YS1
Moon, HI1
Shimada, S1
Yamauchi, M1
Takamatsu, M1
Uetake, S1
Ohata, M1
Saito, S1
Freeman, TL3
Willis, MS2
Tuma, DJ14
Kuszynski, CA1
Nakajima, T1
Kamijo, Y1
Tanaka, N1
Sugiyama, E1
Tanaka, E1
Kiyosawa, K1
Fukushima, Y1
Peters, JM1
Gonzalez, FJ1
Aoyama, T1
Latvala, J1
Hietala, J1
Koivisto, H1
Järvi, K1
Anttila, P1
Niemelä, O12
Worrall, S6
Parkkila, S6
Emery, PW1
Preedy, VR1
Seitz, HK3
Salaspuro, M2
Savolainen, M1
Haber, P1
Ishii, H2
Teschke, R2
Moshage, H1
Lieber, CS16
Kannarkat, GT1
Crabb, DW1
Foschi, M1
Tarocchi, M1
Patussi, V1
Moraldi, L1
Moretti, R1
Milani, S1
Surrenti, C1
Jelski, W1
Chrostek, L1
Szmitkowski, M1
Rao, RK1
Purohit, V1
Bode, JC1
Bode, C1
Brenner, DA1
Choudhry, MA1
Hamilton, F1
Kang, YJ1
Keshavarzian, A1
Sartor, RB1
Swanson, C1
Turner, JR1
Jenkins, W1
Renger, F1
Lewis, KO1
Paton, A1
García-Buñuel, L1
Thurman, RG2
Ji, S1
Lemasters, JJ1
Yoshihara, H1
Sato, N2
Kamada, T1
Abe, H1
Sorrell, MF7
Hirayama, C1
Kishimoto, Y1
Wakushima, T1
Murawaki, Y1
Baraona, E4
Nilius, R1
Königstedt, B1
Zipprich, B1
Busse, HJ1
Lorenz, G1
Rothschild, MA1
Oratz, M1
Morland, J1
Schreiber, SS1
Burks, A1
Martin, B1
Yokoyama, H1
Tuma, D1
Ylä-Herttuala, S1
Villanueva, J2
Ruebner, B2
Halsted, CH2
Wicht, F1
Fisch, HU1
Nelles, J1
Raisin, J1
Allemann, P1
Preisig, R1
Takada, A2
Kobayashi, Y1
Harcombe, AA1
Ramsay, L1
Kenna, JG1
Koskinas, J1
Why, HJ1
Richardson, PJ1
Weissberg, PL1
Alexander, GJ1
Svegliati-Baroni, G1
Rosman, AS1
Wickramasinghe, SN1
Corridan, B1
Hasan, R1
Marjot, DH1
Nicholls, RM1
Fowles, LF1
de Jersey, J4
Wilce, PA3
Sherman, DI1
Williams, R1
Lin, RC4
Shahidi, S1
Kelly, TJ1
Lumeng, C1
Lumeng, L2
Paronetto, F1
Albano, E3
Parola, M1
Comoglio, A1
Dianzani, MU1
Chandler, CJ1
Munn, RJ1
Panés, J1
Caballería, J1
Guitart, R1
Parés, A1
Soler, X1
Rodamilans, M1
Navasa, M1
Parés, X1
Bosch, J1
Rodés, J1
Teare, JP1
Carmichael, AJ1
Burnett, FR1
Rake, MO1
Zhang, H2
Loney, LA1
Potter, BJ2
Paradis, V1
Scoazec, JY1
Köllinger, M1
Holstege, A1
Moreau, A1
Feldmann, G1
Bedossa, P1
Löf, K1
Lindros, K1
Seppa, K1
Fukunaga, T2
Badger, T1
Ronis, M1
Sillanaukee, P1
Li, CJ1
Nanji, AA1
Siakotos, AN1
Kurose, I1
Kato, S1
Fillenwarth, MJ2
Du, X1
Nagata, N3
Nishizaki, Y1
Watanabe, N2
Tsuda, M2
Matsuzaki, S2
Loguercio, C1
Clot, P1
Argenzio, F1
Grella, A1
De Girolamo, V1
Delle Cave, M1
Del Vecchio Bianco, C1
Nardi, G1
Clemens, DL1
Casey, CA1
Jayatilleke, A1
Shaw, S3
Koskinen, LK1
Korpela, MM1
Lahtela, JT1
Laippala, PJ1
Pikkarainen, PH1
Koivula, TA1
Pasanen, M2
Iimuro , Y1
Bradford, B1
Tsukamoto, H1
Jones, BL1
Rolla, R1
Vay, D1
Mottaran, E1
Parodi, M1
Traverso, N1
Aricó, S1
Sartori, M1
Bellomo, G1
Viitala, K2
Makkonen, K1
Israel, Y4
Lehtimäki, T1
Jaakkola, O1
Koivula, T1
Blake, JE1
Juvonen, RO1
Gelboin, HV1
Eriksson, CJ1
Wyatt, TA1
Yang, H1
Wang, J1
Huang, ZZ1
Ou, X1
Lu, SC1
Kharbanda, KK1
Todero, SL1
Shubert, KA1
Lindros, KO1
Sipponen, P1
Pikkarainen, P1
Turunen, U1
Day, CP1
Bassendine, MF1
Sidner, RA1
Nicholls, R1
Wilce, P1
Lauterburg, BH1
Brown, K1
Shanley, BC2
Behrens, UJ1
Ma, XL1
Hernández-Muñoz, R2
Uppal, R1
Mihas, AA1
Tavassoli, M1
Trudell, JR1
Ardies, CM1
Green, CE1
Allen, K1
Jennett, RB1
Jayatilleke, E2
Pratt, OE1
Rooprai, HK1
Shaw, GK1
Thomson, AD1
Kennedy, NP1
Tipton, KF1
Hurwitz, E1
Arnon, R1
Khanna, J1
Orrego, H2
Cobden, I1
Matthewson, K2
Carr, WP1
Dick, WC1
Record, CO2
Szczepańska-Szewczyk, M1
Szukalski, B1
Puntarulo, S1
Cederbaum, AI1
Takase, S1
Urashima, S1
Yasuhara, M1
Adachi, J1
Mizoi, Y1
Ogawa, Y1
Imamichi, H1
Kubota, S1
Kawano, S1
Matsumura, T1
Inatomi, N1
Mitchell, MC1
Herlong, HF1
Williams, AJ2
Barry, RE4
Eddleston, AL1
Vento, S1
Peters, TJ1
Ward, RJ1
Fleisher, JH1
Lung, CC1
Meinke, GC1
Pinnas, JL1
Thompson, RP1
Mörikofer-Zwez, S1
Al Mardini, H1
Bartlett, K1
Suwaki, H1
Ihori, M1
McGivan, JD1

Reviews

50 reviews available for acetaldehyde and Liver Diseases, Alcoholic

ArticleYear
[Immune cells role and their new potential therapeutic targets in the pathogenesis of alcoholic liver disease].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2021, Jun-20, Volume: 29, Issue:6

    Topics: Acetaldehyde; Adaptive Immunity; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Oxidative Stress

2021
[Alcoholic liver disease: the roles of genetic-epigenetic factors and the effect of abstinence].
    Orvosi hetilap, 2019, Volume: 160, Issue:14

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Epigenesis, Genetic; Fem

2019
Pathogenesis of alcoholic liver disease: role of oxidative metabolism.
    World journal of gastroenterology, 2014, Dec-21, Volume: 20, Issue:47

    Topics: Acetaldehyde; Adaptive Immunity; Animals; Disease Progression; Ethanol; Humans; Immunity, Innate; Li

2014
Chronic alcohol drinking: Liver and pancreatic cancer?
    Clinics and research in hepatology and gastroenterology, 2015, Volume: 39 Suppl 1

    Topics: Acetaldehyde; Adaptive Immunity; Alcoholism; Carcinoma, Hepatocellular; Central Nervous System Depre

2015
Role of Early Growth Response-1 in the Development of Alcohol-Induced Steatosis.
    Current molecular pharmacology, 2017, Volume: 10, Issue:3

    Topics: Acetaldehyde; Animals; Autophagy; Early Growth Response Protein 1; Gene Expression Regulation; Human

2017
Role of alcohol in liver carcinogenesis.
    Seminars in liver disease, 2009, Volume: 29, Issue:2

    Topics: Acetaldehyde; Alcohol Drinking; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic;

2009
Endotoxemia and gut barrier dysfunction in alcoholic liver disease.
    Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:2

    Topics: Acetaldehyde; Adherens Junctions; Animals; Endotoxemia; Ethanol; Humans; Intestinal Mucosa; Intestin

2009
Post-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications.
    Journal of proteomics, 2011, Nov-18, Volume: 74, Issue:12

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Asian People;

2011
Mechanisms of alcohol liver damage: aldehydes, scavenger receptors, and autoimmunity.
    Frontiers in bioscience : a journal and virtual library, 2004, Sep-01, Volume: 9

    Topics: Acetaldehyde; Aldehydes; Animals; Apoptosis; Autoimmune Diseases; Autoimmunity; CD4-Positive T-Lymph

2004
[Biochemical basic of alcoholic liver injury].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006, Volume: 21, Issue:124

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Animals; Cytochrome P-450 CYP2E1; Ethanol; Fatty Li

2006
Liver disorders in alcoholism.
    Contemporary issues in clinical biochemistry, 1984, Volume: 1

    Topics: Acetaldehyde; Animals; Carcinoma, Hepatocellular; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoho

1984
[Alcohol and the liver].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1981, Aug-15, Volume: 36, Issue:16

    Topics: Acetaldehyde; Carbohydrate Metabolism; Enzyme Induction; Fatty Liver; gamma-Glutamyltransferase; Hep

1981
Alcohol, protein nutrition, and liver injury.
    Current concepts in nutrition, 1983, Volume: 12

    Topics: Acetaldehyde; Animals; Collagen; Cysteine; Dietary Fats; Dietary Proteins; Fatty Acids; Fatty Liver,

1983
Alcohol, liver injury and protein metabolism.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13 Suppl 1

    Topics: Acetaldehyde; Alcoholism; Amino Acids; Carbohydrate Metabolism; Collagen; Dietary Proteins; Ethanol;

1980
Metabolic effects of ethanol on the liver and other digestive organs.
    Clinics in gastroenterology, 1981, Volume: 10, Issue:2

    Topics: Acetaldehyde; Amino Acids; Aminobutyrates; Biotransformation; Carcinogens; Digestive System; Enzyme

1981
Effects of alcohol on hepatic transport of proteins.
    Annual review of medicine, 1982, Volume: 33

    Topics: Acetaldehyde; Albumins; Animals; Biological Transport; Ethanol; Humans; Liver; Liver Diseases, Alcoh

1982
Effects of ethanol on protein synthesis and secretion.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13 Suppl 1

    Topics: Acetaldehyde; Alcoholism; Animals; Dose-Response Relationship, Drug; Ethanol; Humans; Liver; Liver C

1980
Genotypes of ALDH2 related to liver and pulmonary diseases and other genetic factors related to alcoholic liver disease.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1994, Volume: 29, Issue:6

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Asthma; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Syste

1994
Liver damage: mechanisms and management.
    British medical bulletin, 1994, Volume: 50, Issue:1

    Topics: Acetaldehyde; Ethanol; Female; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic;

1994
Biochemical factors in alcoholic liver disease.
    Seminars in liver disease, 1993, Volume: 13, Issue:2

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Body Weight; Catalase; Ethanol; Humans; Liver; Live

1993
Immunologic reactions in alcoholic liver disease.
    Seminars in liver disease, 1993, Volume: 13, Issue:2

    Topics: Acetaldehyde; Antibodies; Cytokines; Hepacivirus; Hepatitis B virus; HLA Antigens; Humans; Immunoglo

1993
Role of oxidative stress and antioxidant therapy in alcoholic and nonalcoholic liver diseases.
    Advances in pharmacology (San Diego, Calif.), 1997, Volume: 38

    Topics: Acetaldehyde; Animals; Antioxidants; Humans; Lipid Peroxidation; Liver Diseases; Liver Diseases, Alc

1997
Susceptibility to alcohol-related liver injury.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1994, Volume: 2

    Topics: Acetaldehyde; Age Factors; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Catalase; Cytokin

1994
[Current aspects of alcohol-induced liver damage].
    Duodecim; laaketieteellinen aikakauskirja, 1995, Volume: 111, Issue:13

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Cytochrome P-450 Enzyme System; Fatty Liver; Female; Hepatitis

1995
Pathogenesis of alcoholic liver disease with particular emphasis on oxidative stress.
    Journal of gastroenterology and hepatology, 1997, Volume: 12, Issue:9-10

    Topics: Acetaldehyde; Animals; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Oxidative Stress; Oxidored

1997
The role of acetaldehyde in the actions of alcohol (update 2000).
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:5 Suppl IS

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol-Induced Disorders; Alcoholic Intoxica

2001
The chemistry and biological effects of malondialdehyde-acetaldehyde adducts.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:5 Suppl IS

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Central Nervou

2001
Distribution of ethanol-induced protein adducts in vivo: relationship to tissue injury.
    Free radical biology & medicine, 2001, Dec-15, Volume: 31, Issue:12

    Topics: Acetaldehyde; Animals; Ethanol; Free Radicals; Humans; Immunity; Lipid Peroxidation; Liver Diseases,

2001
Genetic predisposition to alcoholic liver disease.
    Gut, 1992, Volume: 33, Issue:11

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Ethanol; Female; Genes; Genotype; Humans; Liver; Liver Disease

1992
Modification of proteins and other biological molecules by acetaldehyde: adduct structure and functional significance.
    The International journal of biochemistry, 1992, Volume: 24, Issue:12

    Topics: Acetaldehyde; Animals; Ethanol; Humans; Immunochemistry; In Vitro Techniques; Liver; Liver Diseases,

1992
[Pathogenesis of alcoholic liver disease].
    Schweizerische medizinische Wochenschrift, 1992, Apr-25, Volume: 122, Issue:17

    Topics: Acetaldehyde; Alcoholism; Environment; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Nutritiona

1992
Alcohol, liver, and nutrition.
    Journal of the American College of Nutrition, 1991, Volume: 10, Issue:6

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Collagen; Ethanol; Hormones; Humans; Liver; Liver C

1991
Contribution of exogenous ethanol and endogenous substrates to acetaldehyde-adduct formation in liver injury.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: Acetaldehyde; Alcoholism; Animals; Carbon Tetrachloride Poisoning; Erythrocytes; Ethanol; Humans; Li

1991
Biochemical mechanisms of alcohol-induced hepatic injury.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Animals; Drug Tolerance; Ethanol; Humans; Liver; Li

1991
Effects of acetaldehyde on hepatic proteins.
    Progress in liver diseases, 1990, Volume: 9

    Topics: Acetaldehyde; Animals; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Protein Binding; Proteins

1990
Mechanism of ethanol induced hepatic injury.
    Pharmacology & therapeutics, 1990, Volume: 46, Issue:1

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Endotoxins; Ethanol; Humans; Liver Cirrhosis, Alcoholi

1990
The genesis of alcoholic brain tissue injury.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1990, Volume: 25, Issue:2-3

    Topics: Acetaldehyde; Alcoholism; Animals; Brain; Brain Damage, Chronic; Ethanol; Free Radicals; Humans; Liv

1990
Ethanol metabolism and alcoholic liver disease.
    Essays in biochemistry, 1990, Volume: 25

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Ethanol; Humans; Lipid Peroxidation; Liver; Liver Dise

1990
Alcohol and the liver: metabolism of ethanol, metabolic effects and pathogenesis of injury.
    Acta medica Scandinavica. Supplementum, 1985, Volume: 703

    Topics: Acetaldehyde; Acetates; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Blood G

1985
Immune responses to alcohol metabolites: pathogenic and diagnostic implications.
    Seminars in liver disease, 1988, Volume: 8, Issue:1

    Topics: Acetaldehyde; Antibody Formation; Epitopes; Ethanol; Humans; Immunity, Cellular; Liver Diseases, Alc

1988
[Biochemical aspects of alcoholism. IV. Alcohol-induced diseases of the liver].
    Postepy higieny i medycyny doswiadczalnej, 1989, Volume: 43, Issue:5-6

    Topics: Acetaldehyde; Alcoholism; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Humans; Liver; Live

1989
Alcohol and nutrition: caloric value, bioenergetics, and relationship to liver damage.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Acetaldehyde; Adenosine Triphosphate; Adolescent; Adult; Aged; Alcohol Dehydrogenase; Alcohol Drinki

1986
Metabolism of ethanol and its consequences for the liver and gastrointestinal tract.
    Digestive diseases (Basel, Switzerland), 1988, Volume: 6, Issue:4

    Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Gastrointestinal Diseases; Humans; Liver Diseases, Alcoh

1988
Relevance of immune mediated mechanisms in progressive alcoholic liver injury.
    Molecular aspects of medicine, 1988, Volume: 10, Issue:2

    Topics: Acetaldehyde; Animals; Antibody Formation; Hepatitis B; Humans; Immunity, Cellular; Liver Diseases,

1988
Role of acetaldehyde in the pathogenesis of alcoholic liver disease.
    Molecular aspects of medicine, 1988, Volume: 10, Issue:2

    Topics: Acetaldehyde; Alcoholism; Free Radicals; Humans; Liver Diseases, Alcoholic

1988
Role of acetaldehyde in the pathogenesis of alcoholic liver disease.
    British journal of addiction, 1988, Volume: 83, Issue:12

    Topics: Acetaldehyde; Alcoholism; Humans; Liver; Liver Diseases, Alcoholic

1988
Measuring the damage--ethanol and the liver.
    Gut, 1986, Volume: 27, Issue:7

    Topics: Acetaldehyde; Aldehyde Oxidoreductases; Ethanol; Female; Gastric Emptying; Humans; Intestinal Absorp

1986
Alcohol and alcohol problems research 2. Japan.
    British journal of addiction, 1985, Volume: 80, Issue:2

    Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Female; Fetal Alcohol Spectrum D

1985
[Alcoholic liver injuries].
    Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:6

    Topics: Acetaldehyde; Animals; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Humans; Liver; Liver D

1985
Covalent binding of acetaldehyde to hepatic proteins: role in alcoholic liver injury.
    Progress in clinical and biological research, 1985, Volume: 183

    Topics: Acetaldehyde; Animals; Ascorbic Acid; Ethanol; In Vitro Techniques; Liver; Liver Diseases, Alcoholic

1985

Trials

1 trial available for acetaldehyde and Liver Diseases, Alcoholic

ArticleYear
Effect of acetaldehyde and acetylsalicylic acid on HbA1c chromatography in the FPLC method with Mono S cation exchanger.
    Clinica chimica acta; international journal of clinical chemistry, 1998, Jul-06, Volume: 275, Issue:1

    Topics: Acetaldehyde; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cation Exchange Resins; Chrom

1998

Other Studies

98 other studies available for acetaldehyde and Liver Diseases, Alcoholic

ArticleYear
Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Acetaldehyde; Adult; Alcoholism; Biomarkers; Fatty Liver; Humans; Immunoglobulin A; Immunoglobulin G

2022
A novel reactive aldehyde species inhibitor prevents the deleterious effects of ethanol in an animal model of alcoholic liver disease.
    International immunopharmacology, 2022, Volume: 113, Issue:Pt A

    Topics: Acetaldehyde; Aldehydes; Animals; Disease Models, Animal; Ethanol; Liver Diseases, Alcoholic; Malond

2022
A novel reactive aldehyde species inhibitor prevents the deleterious effects of ethanol in an animal model of alcoholic liver disease.
    International immunopharmacology, 2022, Volume: 113, Issue:Pt A

    Topics: Acetaldehyde; Aldehydes; Animals; Disease Models, Animal; Ethanol; Liver Diseases, Alcoholic; Malond

2022
A novel reactive aldehyde species inhibitor prevents the deleterious effects of ethanol in an animal model of alcoholic liver disease.
    International immunopharmacology, 2022, Volume: 113, Issue:Pt A

    Topics: Acetaldehyde; Aldehydes; Animals; Disease Models, Animal; Ethanol; Liver Diseases, Alcoholic; Malond

2022
A novel reactive aldehyde species inhibitor prevents the deleterious effects of ethanol in an animal model of alcoholic liver disease.
    International immunopharmacology, 2022, Volume: 113, Issue:Pt A

    Topics: Acetaldehyde; Aldehydes; Animals; Disease Models, Animal; Ethanol; Liver Diseases, Alcoholic; Malond

2022
Alcohol-induced tubulin post-translational modifications directly alter hepatic protein trafficking.
    Hepatology communications, 2023, 04-01, Volume: 7, Issue:4

    Topics: Acetaldehyde; Animals; Ethanol; Humans; Liver Diseases, Alcoholic; Mice; Protein Processing, Post-Tr

2023
Hepatic progesterone receptor membrane component 1 attenuates ethanol-induced liver injury by reducing acetaldehyde production and oxidative stress.
    American journal of physiology. Gastrointestinal and liver physiology, 2023, 06-01, Volume: 324, Issue:6

    Topics: Acetaldehyde; Animals; Chemical and Drug Induced Liver Injury, Chronic; Ethanol; Humans; Liver; Live

2023
Mulberry leaves extract ameliorates alcohol-induced liver damages through reduction of acetaldehyde toxicity and inhibition of apoptosis caused by oxidative stress signals.
    International journal of medical sciences, 2021, Volume: 18, Issue:1

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Enzy

2021
CD39-mediated ATP-adenosine signalling promotes hepatic stellate cell activation and alcoholic liver disease.
    European journal of pharmacology, 2021, Aug-15, Volume: 905

    Topics: 5'-Nucleotidase; Acetaldehyde; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Ca

2021
NOX4 Regulates CCR2 and CCL2 mRNA Stability in Alcoholic Liver Disease.
    Scientific reports, 2017, 04-06, Volume: 7

    Topics: Acetaldehyde; Alcohol Drinking; Animals; Cell Nucleus; Cells, Cultured; Chemokine CCL2; ELAV-Like Pr

2017
Mitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: A molecular mechanism of protection against alcoholic liver disease.
    Redox biology, 2018, Volume: 14

    Topics: Acetaldehyde; Aldehyde Dehydrogenase, Mitochondrial; Animals; Cell Line; Liver Diseases, Alcoholic;

2018
Liver tissue metabolically transformed by alcohol induces immune recognition of liver self-proteins but not in vivo inflammation.
    American journal of physiology. Gastrointestinal and liver physiology, 2018, 03-01, Volume: 314, Issue:3

    Topics: Acetaldehyde; Adoptive Transfer; Animals; Autoimmunity; Cell Movement; Cells, Cultured; Disease Mode

2018
Protective Effects of Facilitated Removal of Blood Alcohol and Acetaldehyde Against Liver Injury in Animal Models Fed Alcohol and Anti-HIV Drugs.
    Alcoholism, clinical and experimental research, 2019, Volume: 43, Issue:6

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Animals; Anti-HIV Agents; Catalase; D

2019
RNA interference against discoidin domain receptor 2 ameliorates alcoholic liver disease in rats.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Acetaldehyde; Animals; Apoptosis; Cell Line; Cell Proliferation; Collagen Type I; Discoidin Domain R

2013
Protective effect of cordycepin-enriched Cordyceps militaris on alcoholic hepatotoxicity in Sprague-Dawley rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 60

    Topics: Acetaldehyde; Alanine Transaminase; Alcohol Drinking; Alkaline Phosphatase; Animals; Aspartate Amino

2013
Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetaldehyde; Aldehydes; Animals; Cells, Cultured; Ethanol; Glutathione; Glycation End Products, Adv

2013
Effects of Beverages on Alcohol Metabolism: Potential Health Benefits and Harmful Impacts.
    International journal of molecular sciences, 2016, Mar-09, Volume: 17, Issue:3

    Topics: Acetaldehyde; Alanine Transaminase; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Aspartat

2016
Purinergic P2X7 receptor mediates acetaldehyde-induced hepatic stellate cells activation via PKC-dependent GSK3β pathway.
    International immunopharmacology, 2017, Volume: 43

    Topics: Acetaldehyde; Adenosine Triphosphate; Animals; Cells, Cultured; Fibrosis; Glycogen Synthase Kinase 3

2017
Potential relationship between hepatobiliary osteopontin and peroxisome proliferator-activated receptor alpha expression following ethanol-associated hepatic injury in vivo and in vitro.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 106, Issue:1

    Topics: Acetaldehyde; Animals; Bezafibrate; Bile Ducts; Cell Line, Tumor; Disease Models, Animal; Epithelial

2008
Acetaldehyde-induced mitochondrial dysfunction sensitizes hepatocytes to oxidative damage.
    Cell biology and toxicology, 2009, Volume: 25, Issue:6

    Topics: Acetaldehyde; Adenosine Triphosphate; Animals; Antimycin A; Cell Respiration; Cell Survival; Drug Sy

2009
Role of aldehyde dehydrogenase-2 in alcoholic liver disease.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:5-6

    Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Anima

2009
Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-alpha production in cultured macrophage cell lines.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:5

    Topics: Acetaldehyde; Acetates; Acetylation; Adiponectin; Animals; Benzamides; Cell Line; Enzyme Inhibitors;

2009
Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices.
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:12

    Topics: Acetaldehyde; Actins; Animals; Brassica; Cell Survival; Collagen; Ethanol; Hepatic Stellate Cells; I

2010
Hepatoprotective effects on alcoholic liver disease of fermented silkworms with Bacillus subtilis and Aspergillus kawachii.
    International journal of food sciences and nutrition, 2012, Volume: 63, Issue:5

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Animals; Antioxidants; Aspartate Amin

2012
Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:7

    Topics: Acetaldehyde; Animals; Ethanol; Hepatic Stellate Cells; Indoles; Liver; Liver Diseases, Alcoholic; M

2012
Experimental studies on the relationship between immune responses and liver damage induced by ethanol after immunization with homologous acetaldehyde adducts.
    Alcoholism, clinical and experimental research, 2002, Volume: 26, Issue:8 Suppl

    Topics: Acetaldehyde; Animals; Autoimmune Diseases; Immunization; Liver; Liver Diseases, Alcoholic; Liver Fu

2002
Chronic ethanol consumption impairs receptor-mediated endocytosis of MAA-modified albumin by liver endothelial cells.
    Biochemical pharmacology, 2003, Sep-15, Volume: 66, Issue:6

    Topics: Acetaldehyde; Albumins; Alcohol Drinking; Animals; Binding Sites; Central Nervous System Depressants

2003
Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage.
    Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:4

    Topics: Acetaldehyde; Animals; Apoptosis; Cell Division; Central Nervous System Depressants; Ethanol; Hepato

2004
Immune Responses to Ethanol Metabolites and Cytokine Profiles Differentiate Alcoholics with or without Liver Disease.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:6

    Topics: Acetaldehyde; Adult; Alcohol Drinking; Antibodies, Anticardiolipin; Autoantigens; Autoimmunity; Biom

2005
Recent advances in alcohol-induced adduct formation.
    Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:7

    Topics: Acetaldehyde; Alcohol-Related Disorders; Alcoholism; Animals; Cardiomyopathy, Alcoholic; DNA Adducts

2005
From alcohol toxicity to treatment.
    Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:7

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol-Related Disorders; Alcoholism; Alleles; Cholestasis, In

2005
Microtubules are more stable and more highly acetylated in ethanol-treated hepatic cells.
    Journal of hepatology, 2006, Volume: 44, Issue:5

    Topics: Acetaldehyde; Acetylation; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Central Nervous Sys

2006
Acetaldehyde inhibits PPARgamma via H2O2-mediated c-Abl activation in human hepatic stellate cells.
    Gastroenterology, 2006, Volume: 131, Issue:4

    Topics: Acetaldehyde; Animals; Cells, Cultured; Central Nervous System Depressants; Collagen; Ethanol; Extra

2006
Acetaldehyde-induced barrier disruption and paracellular permeability in Caco-2 cell monolayer.
    Methods in molecular biology (Clifton, N.J.), 2008, Volume: 447

    Topics: Acetaldehyde; Caco-2 Cells; Cell Culture Techniques; Cell Survival; Electric Impedance; Endotoxins;

2008
Formation and immunological properties of aldehyde-derived protein adducts following alcohol consumption.
    Methods in molecular biology (Clifton, N.J.), 2008, Volume: 447

    Topics: Acetaldehyde; Alcohol Drinking; Aldehydes; Animals; Antibodies; Antibodies, Monoclonal; Antibody Spe

2008
Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium.
    Alcohol (Fayetteville, N.Y.), 2008, Volume: 42, Issue:5

    Topics: Acetaldehyde; Alcohol Drinking; Animals; Avena; Bacterial Translocation; Burns; Endotoxins; ErbB Rec

2008
[Alcoholic liver diseases. Biochemical and clinical studies on pathogenesis and early diagnosis].
    Fortschritte der Medizin, 1980, Jun-19, Volume: 98, Issue:23

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Biochemical Phenomena; Biochemistry; Catalase; Chlorpromazine

1980
Could superoxide cause cirrhosis?
    Lancet (London, England), 1982, Jul-24, Volume: 2, Issue:8291

    Topics: Acetaldehyde; Humans; Lipid Metabolism; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic

1982
Aldehyde dehydrogenase and alcoholism.
    Lancet (London, England), 1983, Feb-12, Volume: 1, Issue:8320

    Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Cytosol; Humans; Liver; Liver Diseases, Alcoholi

1983
Lipid peroxidation in alcoholic myopathy and cardiomyopathy.
    Medical hypotheses, 1984, Volume: 13, Issue:2

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Cardiomyopathy, Alcoholic; Catalase; Eth

1984
Alcohol-induced liver injury. The role of oxygen.
    Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism, 1984, Volume: 2

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Humans; L-Lactate

1984
[Metabolic aspects of alcoholic liver damage: 1984/5 update. 1. Epidemiology and alcohol metabolism].
    Zeitschrift fur Gastroenterologie, 1984, Volume: 22, Issue:12

    Topics: Acetaldehyde; Acidosis; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Collagen;

1984
Low Km ALDH isozyme and alcoholic liver injury.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18 Suppl 1

    Topics: Acetaldehyde; Adolescent; Adult; Aged; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Oxidoreduc

1983
Effect of ethanol on hepatic secretory proteins.
    Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism, 1984, Volume: 2

    Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Animals; Blood Proteins; Ethanol; Glycoproteins; H

1984
Alcohol, protein metabolism, and liver injury.
    Gastroenterology, 1980, Volume: 79, Issue:2

    Topics: Acetaldehyde; Amino Acids; Aminobutyrates; Animals; Collagen; Dietary Proteins; Ethanol; Fatty Acids

1980
Mechanism of the protective action of thiol compounds in ethanol-induced liver injury.
    Biochemical pharmacology, 1983, Jan-15, Volume: 32, Issue:2

    Topics: Acetaldehyde; Animals; Cysteine; Ethanol; Lipid Metabolism; Liver Diseases, Alcoholic; Male; Rats; R

1983
[Acetaldehyde-induced leukocyte migration inhibition in alcoholic liver diseases].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1982, Jun-15, Volume: 37, Issue:12

    Topics: Acetaldehyde; Cell Migration Inhibition; Hepatitis, Alcoholic; Humans; Leukocytes; Liver Cirrhosis,

1982
[Immune response against protein epitopes modified with acetaldehyde and its clinical significance in alcoholic liver diseases].
    Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence, 1993, Volume: 28, Issue:6

    Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Epitopes; Female; Guinea Pigs; Humans; Liver Diseases

1993
Immune mechanisms of alcohol-induced liver disease.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:1

    Topics: Acetaldehyde; Alcohol Drinking; Animals; Antibody Formation; Antigens; Epitopes; Humans; Immune Syst

1995
Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:4 Pt 1

    Topics: Acetaldehyde; Aldehydes; Animals; Guinea Pigs; Immunohistochemistry; Lipid Peroxidation; Liver; Live

1995
Divergence of ethanol and acetaldehyde kinetics and of the disulfiram-alcohol reaction between subjects with and without alcoholic liver disease.
    Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:2

    Topics: Acetaldehyde; Adult; Aged; Combined Modality Therapy; Disulfiram; Dose-Response Relationship, Drug;

1995
Circulating antibodies to cardiac protein-acetaldehyde adducts in alcoholic heart muscle disease.
    Clinical science (London, England : 1979), 1995, Volume: 88, Issue:3

    Topics: Acetaldehyde; Adult; Aged; Antibodies; Biomarkers; Blotting, Western; Cardiomyopathy, Alcoholic; Cyt

1995
Collagen-acetaldehyde adducts in alcoholic and nonalcoholic liver diseases.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:1 Pt 1

    Topics: Acetaldehyde; Adult; Aged; Analysis of Variance; Animals; Aspartate Aminotransferases; Collagen; gam

1994
Correlations between acetaldehyde-modified haemoglobin, carbohydrate-deficient transferrin (CDT) and haematological abnormalities in chronic alcoholism.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1994, Volume: 29, Issue:4

    Topics: Acetaldehyde; Adult; Alcoholism; Bilirubin; Blood Cell Count; Enzymes; Erythrocyte Indices; Female;

1994
Distribution and turnover of acetaldehyde-modified proteins in liver and blood of ethanol-fed rats.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1994, Volume: 29, Issue:2

    Topics: Acetaldehyde; Alcoholism; Animals; Blood Proteins; Cytosol; Enzyme-Linked Immunosorbent Assay; Ethan

1994
Measurement of hemoglobin-acetaldehyde adduct in alcoholic patients.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:3

    Topics: Acetaldehyde; Alcoholism; Enzyme-Linked Immunosorbent Assay; Female; Hemoglobins; Humans; Liver Dise

1993
Evidence for the covalent binding of hydroxyethyl radicals to rat liver microsomal proteins.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1993, Volume: 28, Issue:4

    Topics: Acetaldehyde; Animals; Binding Sites; Ethanol; Free Radicals; Hydroxyl Radical; Liver Diseases, Alco

1993
Centrilobular distribution of acetaldehyde and collagen in the ethanol-fed micropig.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:4

    Topics: Acetaldehyde; Animals; Collagen; Disease Models, Animal; Ethanol; Iron; Liver; Liver Diseases, Alcoh

1993
Determinants of ethanol and acetaldehyde metabolism in chronic alcoholics.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:1

    Topics: Acetaldehyde; Adult; Aged; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Femal

1993
Detection of antibodies to acetaldehyde-albumin conjugates in alcoholic liver disease.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1993, Volume: 28, Issue:1

    Topics: Acetaldehyde; Autoantibodies; Autoantigens; Blood Proteins; Enzyme-Linked Immunosorbent Assay; Fatty

1993
Effect of chronic alcohol feeding on hepatic iron status and ferritin uptake by rat hepatocytes.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:2

    Topics: Acetaldehyde; Alcoholism; Animals; Cells, Cultured; Ferritins; Iron; Liver; Liver Diseases, Alcoholi

1993
Cellular and subcellular localization of acetaldehyde-protein adducts in liver biopsies from alcoholic patients.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1996, Volume: 44, Issue:9

    Topics: Acetaldehyde; Animals; Biopsy; Cells, Cultured; Cytosol; Endoplasmic Reticulum; Humans; Immunohistoc

1996
The effect of ethanol or hepatotoxin exposure on rat transferrin desialylation.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1996, Volume: 31, Issue:5

    Topics: Acetaldehyde; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethan

1996
Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:3

    Topics: Acetaldehyde; Aldehydes; Animals; Antibodies; Corn Oil; Dietary Fats; Fatty Liver; Fish Oils; Humans

1997
Cytotoxic effect of 7alpha-hydroxy-4-cholesten-3-one on HepG2 cells: hypothetical role of acetaldehyde-modified delta4-3-ketosteroid-5beta-reductase (the 37-kd-liver protein) in the pathogenesis of alcoholic liver injury in the rat.
    Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:1

    Topics: Acetaldehyde; Animals; Cell Death; Cell Line; Cell Nucleus; Cholestenones; Culture Media; DNA Fragme

1998
An enzyme immune assay for serum anti-acetaldehyde adduct antibody using low-density lipoprotein adduct and its significance in alcoholic liver injury.
    Alcoholism, clinical and experimental research, 1998, Volume: 22, Issue:S3 Pt 1

    Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Animals; Antibodies; Cattle; Female; Humans; Immunoenz

1998
Free radicals and not acetaldehyde influence the circulating levels of glutathione after acute or chronic alcohol abuse: in vivo and in vitro studies.
    Italian journal of gastroenterology and hepatology, 1997, Volume: 29, Issue:2

    Topics: Acetaldehyde; Acute Disease; Adult; Alcoholic Intoxication; Alcoholism; Chronic Disease; Erythrocyte

1997
Ethanol oxidation mediates impaired hepatic receptor-mediated enocytosis.
    Alcoholism, clinical and experimental research, 1998, Volume: 22, Issue:4

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Asialoglycoprotein Receptor; Cell Line, Transformed; E

1998
Stimulation of monocyte interleukin-8 by lipid peroxidation products: a mechanism for alcohol-induced liver injury.
    Alcohol (Fayetteville, N.Y.), 1998, Volume: 16, Issue:2

    Topics: Acetaldehyde; alpha-Linolenic Acid; Arachidonic Acid; Ethanol; Humans; Hydrocortisone; Interleukin-8

1998
Early alcoholic liver injury: formation of protein adducts with acetaldehyde and lipid peroxidation products, and expression of CYP2E1 and CYP3A.
    Alcoholism, clinical and experimental research, 1998, Volume: 22, Issue:9

    Topics: Acetaldehyde; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3

1998
Relationship between serum levels of anti-low-density lipoprotein-acetaldehyde-adduct antibody and aldehyde dehydrogenase 2 heterozygotes in patients with alcoholic liver injury.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:4 Suppl

    Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitoch

1999
Conversion of acetaldehyde-protein adduct epitopes from a nonreduced to a reduced phenotype by antigen processing cells.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:4

    Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Antibody Formation; Antigen Presentation; Antigen-Pre

1999
Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease.
    Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:4

    Topics: Acetaldehyde; Adult; Aged; Antibodies; Antibody Specificity; Enzyme-Linked Immunosorbent Assay; Epit

2000
Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers.
    Alcoholism, clinical and experimental research, 2000, Volume: 24, Issue:7

    Topics: Acetaldehyde; Alcohol Drinking; Analysis of Variance; Autoantibodies; Autoimmunity; Chi-Square Distr

2000
Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases.
    Journal of hepatology, 2000, Volume: 33, Issue:6

    Topics: Acetaldehyde; Adipose Tissue; Adult; Aldehydes; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2

2000
Cloning and characterization of the 5'-flanking region of the rat glutamate-cysteine ligase catalytic subunit.
    The Biochemical journal, 2001, Jul-15, Volume: 357, Issue:Pt 2

    Topics: 5' Untranslated Regions; Acetaldehyde; Animals; Base Sequence; Catalysis; Cell Line; Cloning, Molecu

2001
Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells.
    Alcohol (Fayetteville, N.Y.), 2001, Volume: 25, Issue:2

    Topics: Acetaldehyde; Animals; Cells, Cultured; Chemokine CCL2; Chemokine CXCL2; Chemokines; Dose-Response R

2001
Alcoholic liver damage is provoked by 4-methylpyrazole, which prolongs the influence of ethanol but reduces acetaldehyde levels.
    Alcoholism, clinical and experimental research, 1979, Volume: 3, Issue:1

    Topics: Acetaldehyde; Animals; Drug Interactions; Ethanol; Liver; Liver Diseases, Alcoholic; Male; Pyrazoles

1979
Immune responses to acetaldehyde-protein adducts: role in alcoholic liver disease.
    Gastroenterology, 1992, Volume: 103, Issue:6

    Topics: Acetaldehyde; Humans; Immunoglobulin A; Liver Diseases, Alcoholic; Proteins

1992
Localization of protein-acetaldehyde adducts on cell surface of hepatocytes by flow cytometry.
    Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:6

    Topics: Acetaldehyde; Animals; Cytosol; Flow Cytometry; Liver; Liver Diseases, Alcoholic; Male; Membrane Pro

1992
The effect of ethanol metabolism on ferritin uptake by freshly isolated rat hepatocytes: is acetaldehyde responsible for this alteration?
    Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:2

    Topics: Acetaldehyde; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Ethanol; Ferritins; Hemosi

1992
Alcohol hepatotoxicity: a genotypic predisposition?
    The American journal of gastroenterology, 1992, Volume: 87, Issue:5

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Disease Susceptibility; Female; Heterozygote; Humans; Liver Di

1992
Antibodies against acetaldehyde-modified epitopes: an elevated IgA response in alcoholics.
    European journal of clinical investigation, 1991, Volume: 21, Issue:1

    Topics: Acetaldehyde; Alcoholism; Epitopes; Hemoglobins; Humans; Immunoglobulin A; Liver; Liver Diseases; Li

1991
The effect of ethanol on the uptake, binding, and desialylation of transferrin by rat liver endothelium: implications in the pathogenesis of alcohol-associated hepatic siderosis.
    The American journal of the medical sciences, 1991, Volume: 301, Issue:5

    Topics: Acetaldehyde; Acetates; Animals; Biological Transport; Endothelium; Ethanol; In Vitro Techniques; Ir

1991
Binding of anti-acetaldehyde IgG antibodies to hepatocytes with an acetaldehyde-phosphatidylethanolamine adduct on their surface.
    Alcoholism, clinical and experimental research, 1991, Volume: 15, Issue:2

    Topics: Acetaldehyde; Animals; Cell Membrane; Cross Reactions; Immunoglobulin G; Liver; Liver Diseases, Alco

1991
Ethanol-induced iron mobilization: role of acetaldehyde-aldehyde oxidase generated superoxide.
    Free radical biology & medicine, 1990, Volume: 9, Issue:1

    Topics: Acetaldehyde; Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Colorimetry; Ethanol; Ferritins;

1990
Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:20

    Topics: Acetaldehyde; Alcoholism; Animals; Antibodies, Monoclonal; Antibody Formation; Blood Proteins; Epito

1986
Antibodies against acetaldehyde- modified epitopes: a new perspective.
    Progress in clinical and biological research, 1987, Volume: 241

    Topics: Acetaldehyde; Antibodies; Antibody Specificity; Antigen-Antibody Complex; Epitopes; Humans; Liver Di

1987
Effect of ethanol challenge on serum glycoproteins in alcoholic and non-alcoholic liver disease.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1987, Volume: 22, Issue:3

    Topics: Acetaldehyde; alpha-Macroglobulins; Ethanol; Glycoproteins; Haptoglobins; Humans; Liver Cirrhosis; L

1987
Ethanol induces the production of antibodies to acetaldehyde-modified epitopes in rats.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1989, Volume: 24, Issue:3

    Topics: Acetaldehyde; Alcoholism; Animals; Autoantibodies; Autoantigens; Carrier Proteins; Epitopes; Ethanol

1989
Chemiluminescence from acetaldehyde oxidation by xanthine oxidase involves generation of and interactions with hydroxyl radicals.
    Alcoholism, clinical and experimental research, 1989, Volume: 13, Issue:1

    Topics: Acetaldehyde; Catalase; Humans; Hydroxides; Hydroxyl Radical; Liver; Liver Diseases, Alcoholic; Lumi

1989
Studies on aldehyde dehydrogenase type V-A isozymes in liver disease.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1989, Volume: 24, Issue:6

    Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Humans; Isoenzymes; Liver Cirrhosis, Alcohol

1989
Comparative study on ethanol elimination and blood acetaldehyde between alcoholics and control subjects.
    Alcoholism, clinical and experimental research, 1989, Volume: 13, Issue:5

    Topics: Acetaldehyde; Adult; Aged; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Humans; Liver Diseases, Alco

1989
Impaired oxygen utilization. A new mechanism for the hepatotoxicity of ethanol in sub-human primates.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:5

    Topics: Acetaldehyde; Animals; Ethanol; Indocyanine Green; Liver; Liver Diseases, Alcoholic; Oxidation-Reduc

1989
[Metabolic aspects of alcoholic liver damage: 1984/1985 update. 2: Microsomal enzyme induction and hypermetabolism].
    Zeitschrift fur Gastroenterologie, 1985, Volume: 23, Issue:1

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Enzyme

1985
Superoxide anion production and degranulation of rat neutrophils in response to acetaldehyde-altered liver cell membranes.
    Clinical science (London, England : 1979), 1986, Volume: 71, Issue:3

    Topics: Acetaldehyde; Animals; Cell Membrane; Female; Free Radicals; Liver; Liver Diseases, Alcoholic; Neutr

1986
Acetaldehyde-mediated hepatic lipid peroxidation: role of superoxide and ferritin.
    Biochemical and biophysical research communications, 1987, Mar-30, Volume: 143, Issue:3

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Ethanol; Ferritins; In Vitro Techniques; Lipid Peroxid

1987
Acetaldehyde-albumin adduct formation: possible relevance to an immunologic mechanism in alcoholism.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1988, Volume: 23, Issue:2

    Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Enzyme-Linked Immunosorbent Assay; Haptens; H

1988
[Alcohol: biochemistry and health].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1987, Mar-17, Volume: 76, Issue:12

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Humans; Liver; Liv

1987
Impaired acetaldehyde metabolism in patients with non-alcoholic liver disorders.
    Gut, 1986, Volume: 27, Issue:7

    Topics: Acetaldehyde; Adult; Aged; Aldehyde Dehydrogenase; Chromatography, Gas; Cytosol; Ethanol; Female; Hu

1986
Acetaldehyde alone may initiate hepatocellular damage in acute alcoholic liver disease.
    Gut, 1985, Volume: 26, Issue:10

    Topics: Acetaldehyde; Cell Membrane; Complement Activation; Complement C3; Humans; Liver; Liver Diseases, Al

1985