acetaldehyde has been researched along with Leucocythaemia in 3 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alkylation of DNA by acrolein and/or chloroacetaldehyde may result in the mutations that lead to the therapy-induced leukemia associated with cyclophosphamide (and ifosfamide) treatment." | 3.71 | Modified guanines representing O(6)-alkylation by the cyclophosphamide metabolites acrolein and chloroacetaldehyde: synthesis, stability, and ab initio studies. ( Balu, N; Colvin, ME; Colvin, OM; Dolan, ME; Gamcsik, MP; Ludeman, SM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liviac, D | 1 |
| Creus, A | 1 |
| Marcos, R | 1 |
| Garaycoechea, JI | 1 |
| Crossan, GP | 1 |
| Langevin, F | 1 |
| Daly, M | 1 |
| Arends, MJ | 1 |
| Patel, KJ | 1 |
| Balu, N | 1 |
| Gamcsik, MP | 1 |
| Colvin, ME | 1 |
| Colvin, OM | 1 |
| Dolan, ME | 1 |
| Ludeman, SM | 1 |
3 other studies available for acetaldehyde and Leucocythaemia
| Article | Year |
|---|---|
DNA damage induction by two halogenated acetaldehydes, byproducts of water disinfection.
Topics: Acetaldehyde; Cells, Cultured; Chloral Hydrate; Chromosome Breakage; DNA Damage; DNA Repair; Humans; | 2010 |
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.
Topics: Acetaldehyde; Aging; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Anima | 2012 |
Modified guanines representing O(6)-alkylation by the cyclophosphamide metabolites acrolein and chloroacetaldehyde: synthesis, stability, and ab initio studies.
Topics: Acetaldehyde; Acrolein; Alkylation; Antineoplastic Agents, Alkylating; Cyclophosphamide; DNA Damage; | 2002 |