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acetaldehyde and Laryngeal Neoplasms

acetaldehyde has been researched along with Laryngeal Neoplasms in 5 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Laryngeal Neoplasms: Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.

Research Excerpts

ExcerptRelevanceReference
"As acetaldehyde seems to be a carcinogenic factor associated with chronic alcohol consumption, alcoholics with the alcohol dehydrogenase (ADH) 1C*1 allele seem to be particularly at risk as this allele encodes for a rapidly ethanol metabolising enzyme leading to increased acetaldehyde levels."1.32Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde. ( Benesova, M; Conradt, C; Götte, K; Homann, N; Hörrmann, K; Inoue, H; Li, J; Salaspuro, M; Seitz, HK; Tisch, M; Väkeväinen, S; Visapää, JP, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Ye, Y1
Wu, T1
Liang, F1
Fan, J1
Song, P1
Li, Y1
Xie, W1
Huang, X1
Han, P1
Visapää, JP1
Götte, K1
Benesova, M1
Li, J1
Homann, N1
Conradt, C1
Inoue, H1
Tisch, M1
Hörrmann, K1
Väkeväinen, S1
Salaspuro, M3
Seitz, HK1
Kartal, A1
Hietala, J1
Laakso, I1
Kaihovaara, P1
Salaspuro, V1
Säkkinen, M1
Marvola, M1
Jokelainen, K1
Heikkonen, E1
Roine, R1
Lehtonen, H1
Woutersen, RA1
Appelman, LM1
Van Garderen-Hoetmer, A1
Feron, VJ1

Other Studies

5 other studies available for acetaldehyde and Laryngeal Neoplasms

ArticleYear
Prognostic Significance of a Model Based on Acetaldehyde Dehydrogenase 2 Genetic Polymorphisms in Laryngeal Carcinoma.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2023, Volume: 169, Issue:3

    Topics: Acetaldehyde; Aldehyde Dehydrogenase, Mitochondrial; Carcinoma; Humans; Laryngeal Neoplasms; Nomogra

2023
Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde.
    Gut, 2004, Volume: 53, Issue:6

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Ethanol; Female; Gene Frequency; Genotype; Humans;

2004
Formulation and in-vivo evaluation of L-cysteine chewing gums for binding carcinogenic acetaldehyde in the saliva during smoking.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:10

    Topics: Acetaldehyde; Adult; Carcinogens; Chewing Gum; Cysteine; Female; Humans; Laryngeal Neoplasms; Male;

2007
Increased acetaldehyde production by mouthwashings from patients with oral cavity, laryngeal, or pharyngeal cancer.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:7

    Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Carcinoma, Squamous Cell; Ethanol; F

1996
Inhalation toxicity of acetaldehyde in rats. III. Carcinogenicity study.
    Toxicology, 1986, Volume: 41, Issue:2

    Topics: Acetaldehyde; Adenocarcinoma; Administration, Inhalation; Animals; Body Weight; Carcinoma, Squamous

1986