acetaldehyde has been researched along with Kidney Diseases in 10 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The toxic metabolite of IFO thought to be responsible for IFO-induced kidney damage is chloroacetaldehyde (CAA)." | 2.45 | Ifosfamide nephrotoxicity in children: a mechanistic base for pharmacological prevention. ( Chen, N; Hanly, L; Koren, G; Rieder, M, 2009) |
| "Orellanine is a nephrotoxic bipyridine N-oxide found in some Cortinarius species." | 2.42 | Cytotoxic fungi--an overview. ( Karlson-Stiber, C; Persson, H, 2003) |
| "Chloroacetaldehyde toxicity was demonstrated by the decrease in total glutathione and cellular ATP levels." | 1.36 | Targets of chloroacetaldehyde-induced nephrotoxicity. ( Baverel, G; Dubourg, L; Knouzy, B; Michoudet, C, 2010) |
| " Despite this, none of the adverse effects of 0." | 1.35 | In vivo mesna and amifostine do not prevent chloroacetaldehyde nephrotoxicity in vitro. ( Baverel, G; Dubourg, L; Michoudet, C; Yaseen, Z, 2008) |
| "Ifosfamide treatment significantly inhibited oxidative phosphorylation with only C-I substrates." | 1.33 | Ifosfamide-induced nephrotoxicity: mechanism and prevention. ( Daikhin, Y; Horyn, O; Luhovyy, B; Nissim, I; Phillips, PC; Yudkoff, M, 2006) |
| "Chloroacetaldehyde (CAA) is a metabolite of the alkylating agent ifosfamide (IFO) and putatively responsible for renal damage following anti-tumor therapy with IFO." | 1.33 | Chloroacetaldehyde as a sulfhydryl reagent: the role of critical thiol groups in ifosfamide nephropathy. ( Benesic, A; Freudinger, R; Gekle, M; Groezinger, F; Kirchhoff, A; Mildenberger, S; Schwerdt, G; Wollny, B, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hanly, L | 1 |
| Chen, N | 1 |
| Rieder, M | 1 |
| Koren, G | 2 |
| Knouzy, B | 1 |
| Dubourg, L | 2 |
| Baverel, G | 2 |
| Michoudet, C | 2 |
| Karlson-Stiber, C | 1 |
| Persson, H | 1 |
| Aleksa, K | 1 |
| Halachmi, N | 1 |
| Ito, S | 1 |
| Benesic, A | 2 |
| Schwerdt, G | 2 |
| Mildenberger, S | 2 |
| Freudinger, R | 2 |
| Gordjani, N | 1 |
| Gekle, M | 2 |
| Nissim, I | 2 |
| Horyn, O | 1 |
| Daikhin, Y | 1 |
| Luhovyy, B | 1 |
| Phillips, PC | 1 |
| Yudkoff, M | 1 |
| Groezinger, F | 1 |
| Wollny, B | 1 |
| Kirchhoff, A | 1 |
| Yaseen, Z | 1 |
| Gincheva, NA | 1 |
| Heller, H | 1 |
2 reviews available for acetaldehyde and Kidney Diseases
| Article | Year |
|---|---|
Ifosfamide nephrotoxicity in children: a mechanistic base for pharmacological prevention.
Topics: Acetaldehyde; Acetylcysteine; Age Factors; Antineoplastic Agents, Alkylating; Antioxidants; Child; H | 2009 |
Cytotoxic fungi--an overview.
Topics: 2,2'-Dipyridyl; Acetaldehyde; Amanitins; Basidiomycota; Humans; Kidney Diseases; Mushroom Poisoning; | 2003 |
8 other studies available for acetaldehyde and Kidney Diseases
| Article | Year |
|---|---|
Targets of chloroacetaldehyde-induced nephrotoxicity.
Topics: Acetaldehyde; Adenosine Triphosphate; Animals; Biotransformation; Enzyme Inhibitors; Enzymes; Glucon | 2010 |
Renal ontogeny of ifosfamide nephrotoxicity.
Topics: Acetaldehyde; Age Factors; Animals; Antineoplastic Agents, Alkylating; Aryl Hydrocarbon Hydroxylases | 2004 |
Disturbed Ca2+-signaling by chloroacetaldehyde: a possible cause for chronic ifosfamide nephrotoxicity.
Topics: Acetaldehyde; Antineoplastic Agents, Alkylating; Calcium; Calcium Signaling; Calcium-Transporting AT | 2005 |
Ifosfamide-induced nephrotoxicity: mechanism and prevention.
Topics: Acetaldehyde; Agmatine; Animals; Antineoplastic Agents, Alkylating; Drug Interactions; Electron Tran | 2006 |
Chloroacetaldehyde as a sulfhydryl reagent: the role of critical thiol groups in ifosfamide nephropathy.
Topics: Acetaldehyde; Antineoplastic Agents, Alkylating; Biomarkers; Caspase 3; Caspase 8; Cathepsin B; Cell | 2006 |
In vivo mesna and amifostine do not prevent chloroacetaldehyde nephrotoxicity in vitro.
Topics: Acetaldehyde; Acetyl Coenzyme A; Adenosine Triphosphate; Amifostine; Animals; Disease Models, Animal | 2008 |
[Toxicological characteristics of the products of the thermal destruction of polyethylene-terephthalate].
Topics: Acetaldehyde; Air Pollution; Animals; Body Temperature; Body Weight; Chemical and Drug Induced Liver | 1971 |
[Importance of enzyme determination in the urine for the diagnosis and control of renal diseases].
Topics: Acetaldehyde; Alanine Transaminase; Aspartate Aminotransferases; Catalase; Chronic Disease; Clinical | 1970 |