acetaldehyde has been researched along with Hepatitis, Alcoholic in 33 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alcoholic hepatitis is a necrotizing, often inflammatory, process that is an important precursor to the development of cirrhosis." | 2.38 | Alcoholic hepatitis: pathogenesis and approaches to treatment. ( Maddrey, WC, 1990) |
| "Acetaldehyde has been proposed as one of the mediators of liver injury in alcoholic liver disease." | 1.30 | Acetaldehyde prevents nuclear factor-kappa B activation and hepatic inflammation in ethanol-fed rats. ( Jokelainen, K; Lindros, KO; Nanji, AA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (45.45) | 18.7374 |
| 1990's | 12 (36.36) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Y | 1 |
| Zhong, W | 1 |
| Sun, X | 1 |
| Song, Z | 1 |
| Clemens, DL | 1 |
| Kang, YJ | 1 |
| McClain, CJ | 1 |
| Zhou, Z | 1 |
| Bushma, MI | 1 |
| Ambrushkevich, YG | 1 |
| Zimatkin, SM | 1 |
| Bushma, KM | 1 |
| Omel'yanchik, SN | 1 |
| Slyshenkov, VS | 1 |
| Mel'nichenko, NG | 1 |
| Kuz'mich, AB | 1 |
| El'chaninova, MA | 1 |
| Stewart, SF | 1 |
| Vidali, M | 1 |
| Day, CP | 1 |
| Albano, E | 2 |
| Jones, DE | 1 |
| Jelski, W | 1 |
| Chrostek, L | 1 |
| Szmitkowski, M | 1 |
| Singh, AK | 1 |
| Jiang, Y | 1 |
| Benlhabib, E | 1 |
| Gupta, S | 1 |
| Jenkins, W | 1 |
| Renger, F | 1 |
| Barry, RE | 2 |
| Nilius, R | 1 |
| Königstedt, B | 1 |
| Zipprich, B | 1 |
| Busse, HJ | 1 |
| Lorenz, G | 1 |
| Kakuma, S | 1 |
| Leevy, CM | 1 |
| Frank, O | 1 |
| Baker, H | 1 |
| Worrall, S | 2 |
| De Jersey, J | 2 |
| Wilce, PA | 2 |
| Baumgarten, R | 1 |
| Niemelä, O | 2 |
| Parkkila, S | 2 |
| Ylä-Herttuala, S | 1 |
| Halsted, C | 1 |
| Witztum, JL | 1 |
| Lanca, A | 1 |
| Israel, Y | 1 |
| Lin, RC | 1 |
| Shahidi, S | 1 |
| Lumeng, L | 1 |
| Teare, JP | 1 |
| Carmichael, AJ | 1 |
| Burnett, FR | 1 |
| Rake, MO | 1 |
| Nagata, N | 1 |
| Watanabe, N | 1 |
| Tsuda, M | 1 |
| Tsukamoto, H | 1 |
| Matsuzaki, S | 1 |
| Lindros, KO | 1 |
| Jokelainen, K | 1 |
| Nanji, AA | 1 |
| Rolla, R | 1 |
| Vay, D | 1 |
| Mottaran, E | 1 |
| Parodi, M | 1 |
| Traverso, N | 1 |
| Aricó, S | 1 |
| Sartori, M | 1 |
| Bellomo, G | 1 |
| Klassen, LW | 1 |
| Thiele, GM | 1 |
| Tuma, DJ | 1 |
| Weir, DG | 1 |
| Van Waes, L | 1 |
| Lieber, CS | 3 |
| Actis, GC | 1 |
| Ponzetto, A | 1 |
| Rizzetto, M | 1 |
| Verme, G | 1 |
| Koskinas, J | 1 |
| Kenna, JG | 1 |
| Bird, GL | 1 |
| Alexander, GJ | 1 |
| Williams, R | 1 |
| Shanley, BC | 1 |
| Zetterman, RK | 1 |
| Maddrey, WC | 1 |
| Szczepańska-Szewczyk, M | 1 |
| Szukalski, B | 1 |
| Black, M | 1 |
| Tavill, AS | 1 |
| Williams, AJ | 1 |
| Fainsilber, Z | 1 |
| Feinman, L | 1 |
| Shaw, S | 1 |
| Matsuda, Y | 1 |
| Takada, A | 1 |
| Yasuhara, M | 1 |
| Sato, H | 1 |
| Ihori, M | 1 |
9 reviews available for acetaldehyde and Hepatitis, Alcoholic
| Article | Year |
|---|---|
[Biochemical basic of alcoholic liver injury].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Animals; Cytochrome P-450 CYP2E1; Ethanol; Fatty Li | 2006 |
Liver disorders in alcoholism.
Topics: Acetaldehyde; Animals; Carcinoma, Hepatocellular; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoho | 1984 |
[Alcohol and the liver].
Topics: Acetaldehyde; Carbohydrate Metabolism; Enzyme Induction; Fatty Liver; gamma-Glutamyltransferase; Hep | 1981 |
[Current aspects of alcohol-induced liver damage].
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Cytochrome P-450 Enzyme System; Fatty Liver; Female; Hepatitis | 1995 |
Immunologic abnormalities in alcoholic hepatitis.
Topics: Acetaldehyde; Animals; Antibody Formation; Hepatitis, Alcoholic; Humans; Immunity, Cellular; Liver; | 1991 |
Alcoholic hepatitis: pathogenesis and approaches to treatment.
Topics: Acetaldehyde; Adrenal Cortex Hormones; Anabolic Agents; Glucagon; Hepatitis, Alcoholic; Humans; Insu | 1990 |
[Biochemical aspects of alcoholism. IV. Alcohol-induced diseases of the liver].
Topics: Acetaldehyde; Alcoholism; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Humans; Liver; Live | 1989 |
Corticosteroids in severe alcoholic hepatitis.
Topics: Acetaldehyde; Adrenal Cortex Hormones; Hepatitis, Alcoholic; Humans; Oxidation-Reduction | 1989 |
[Alcoholic liver injuries].
Topics: Acetaldehyde; Animals; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Humans; Liver; Liver D | 1985 |
24 other studies available for acetaldehyde and Hepatitis, Alcoholic
| Article | Year |
|---|---|
Zinc deprivation mediates alcohol-induced hepatocyte IL-8 analog expression in rodents via an epigenetic mechanism.
Topics: Acetaldehyde; Alcohols; Animals; Carcinoma, Hepatocellular; Enzyme-Linked Immunosorbent Assay; Epige | 2011 |
LPO and ethanol biotransformation systems in the liver as markers of predisposition to ethanol hepatotoxicity.
Topics: Acetaldehyde; Alanine Transaminase; Animals; Ascorbic Acid; Biomarkers; Biotransformation; Ethanol; | 2002 |
Oxidative stress as a trigger for cellular immune responses in patients with alcoholic liver disease.
Topics: Acetaldehyde; Autoantibodies; CD4-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Female; He | 2004 |
Herbal mixtures consisting of puerarin and either polyenylphosphatidylcholine or curcumin provide comprehensive protection against alcohol-related disorders in P rats receiving free choice water and 15% ethanol in pure water.
Topics: Acetaldehyde; Alcohol-Related Disorders; Alcoholism; Animals; Apoptosis; Curcumin; Electroencephalog | 2007 |
The pathogenesis of hepatitis in alcohol abuse and jejunoileal bypass.
Topics: Acetaldehyde; Bacteria; Complement Activation; Erythrocyte Membrane; Ethanol; Female; Hepatitis; Hep | 1983 |
[Acetaldehyde-induced leukocyte migration inhibition in alcoholic liver diseases].
Topics: Acetaldehyde; Cell Migration Inhibition; Hepatitis, Alcoholic; Humans; Leukocytes; Liver Cirrhosis, | 1982 |
Protection of pyridoxal 5'-phosphate against toxicity of acetaldehyde to hepatocytes.
Topics: Acetaldehyde; Benzylamines; Cell Survival; Hepatitis, Alcoholic; Humans; In Vitro Techniques; Liver; | 1981 |
Antibodies from alcoholics, ethanol-fed rats and a rabbit immunised with proteins modified by acetaldehyde in vitro react with liver cytosolic proteins from ethanol-fed rats.
Topics: Acetaldehyde; Alcoholism; Animals; Autoantibodies; Autoantigens; Autoradiography; Blood Protein Elec | 1993 |
[Can toxic alcohol liver parenchyma damage be diagnosed using pathobiochemical parameters?].
Topics: Acetaldehyde; Alanine Transaminase; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aspartate Aminot | 1993 |
Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation.
Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Hepatitis, Alcoholic; Humans; Immunologic Techniques; Li | 1994 |
Production of antibodies that recognize the heterogeneity of immunoreactive sites in human hemoglobin chemically modified by acetaldehyde.
Topics: Acetaldehyde; Antibodies, Heterophile; Antigens, Heterophile; Autoantibodies; Enzyme-Linked Immunoso | 1993 |
Detection of antibodies to acetaldehyde-albumin conjugates in alcoholic liver disease.
Topics: Acetaldehyde; Autoantibodies; Autoantigens; Blood Proteins; Enzyme-Linked Immunosorbent Assay; Fatty | 1993 |
Relationship between serum levels of anti-low-density lipoprotein-acetaldehyde-adduct antibody and aldehyde dehydrogenase 2 heterozygotes in patients with alcoholic liver injury.
Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitoch | 1999 |
Acetaldehyde prevents nuclear factor-kappa B activation and hepatic inflammation in ethanol-fed rats.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Cyclooxygenase 2; Enzyme Inhibitors; Hepatitis, Alcoh | 1999 |
Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease.
Topics: Acetaldehyde; Adult; Aged; Antibodies; Antibody Specificity; Enzyme-Linked Immunosorbent Assay; Epit | 2000 |
The pathophysiology of alcohol and acetaldehyde metabolism in the liver.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Ethanol; Hepatitis, Alcoholic; Humans; I | 1978 |
[Biochemical and morphological changes of the liver in chronic alcoholism].
Topics: Acetaldehyde; Animals; Ethanol; Haplorhini; Hepatitis, Alcoholic; Humans; Liver; Oxidation-Reduction | 1978 |
Cell-mediated immunity to acetaldehyde in alcoholic liver disease demonstrated by leukocyte migration test.
Topics: Acetaldehyde; Adult; Aged; Cell Migration Inhibition; Diagnosis, Differential; Female; Hepatitis, Al | 1978 |
Immunoglobulin A antibody to a 200-kilodalton cytosolic acetaldehyde adduct in alcoholic hepatitis.
Topics: Acetaldehyde; Animals; Antigens; Cytosol; Hepatitis, Alcoholic; Humans; Immunoglobulin A; Male; Prot | 1992 |
Antibodies against acetaldehyde-modified epitopes: presence in alcoholic, non-alcoholic liver disease and control subjects.
Topics: Acetaldehyde; Alcohol Drinking; Autoantibodies; Blood Proteins; Carcinoma, Hepatocellular; Enzyme-Li | 1990 |
Free radical generation by neutrophils: a potential mechanism of cellular injury in acute alcoholic hepatitis.
Topics: Acetaldehyde; Acute Disease; Cell Membrane; Cytochrome c Group; Free Radicals; Hepatitis, Alcoholic; | 1987 |
Biphasic control of polymorphonuclear cell migration by Kupffer cells. Effect of exposure to metabolic products of ethanol.
Topics: Acetaldehyde; Animals; Chemotaxis, Leukocyte; Ethanol; Hepatitis, Alcoholic; Kupffer Cells; Microsom | 1988 |
[From alcohol to cirrhosis].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Ethanol; Hepatitis, Alcoholic; Humans; Liver; Liver Cirrhosis, | 1986 |
Effects of malotilate on alcoholic liver injury in rats.
Topics: Acetaldehyde; Animals; Ethanol; Hepatitis, Alcoholic; Liver; Liver Cirrhosis, Alcoholic; Male; Malon | 1988 |