acetaldehyde has been researched along with Head and Neck Neoplasms in 9 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The presentations were (1) Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotype and cancer risk for upper aerodigestive tract in Japanese alcoholics, by Akira Yokoyama; (2) The role of acetaldehyde in alcohol-associated carcinogenesis, by Nils Homann; (3) High salivary acetaldehyde levels after a moderate dose of alcohol in ALDH2-deficient subjects, by Satu Väkeväinen; (4) Alcohol and vitamin A interactions, by Xian Dong Wang; and (5) Alcohol and colorectal cancer, by Helmut K." | 4.81 | Alcohol and cancer. ( Homann, N; Matsuzaki, S; Seitz, HK; Väkeväinen, S; Wang, XD; Yokoyama, A, 2001) |
| "The acetaldehyde-to-ethanol ratio detected using the acetaldehyde breath test could be a novel biomarker of metachronous recurrence after endoscopic submucosal dissection in patients with esophageal squamous cell carcinoma and hypopharynx squamous cell carcinoma." | 4.31 | Usefulness of the aldehyde breath test for predicting metachronous recurrence in patients with esophageal squamous cell carcinoma and hypopharyngeal squamous cell carcinoma. ( Arima, S; Hashimoto, S; Ido, A; Kanmura, S; Kumagai, K; Maeda, H; Mawatari, S; Oda, K; Sasaki, F; Tanaka, A; Tanoue, S; Yano, H, 2023) |
| "Using RNA-sequencing data from 136 HNSCC patients, we compared the expression levels of 1,046 microRNAs between drinking and non-drinking cohorts." | 1.42 | Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma. ( Kim, E; Korrapati, A; Kuo, SZ; Ongkeko, WM; Rahimy, E; Rahimy, M; Saad, MA; Wang-Rodriguez, J; Yu, MA; Zheng, H; Zou, AE, 2015) |
| "Upon inhibition of these miRNAs, HNSCC cell lines exhibited increased sensitivity to cisplatin and reduced matrigel invasion." | 1.42 | Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma. ( Kim, E; Korrapati, A; Kuo, SZ; Ongkeko, WM; Rahimy, E; Rahimy, M; Saad, MA; Wang-Rodriguez, J; Yu, MA; Zheng, H; Zou, AE, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sasaki, F | 1 |
| Mawatari, S | 1 |
| Oda, K | 1 |
| Yano, H | 1 |
| Maeda, H | 1 |
| Tanaka, A | 1 |
| Arima, S | 1 |
| Kumagai, K | 1 |
| Tanoue, S | 1 |
| Hashimoto, S | 1 |
| Kanmura, S | 1 |
| Ido, A | 1 |
| Koyanagi, YN | 1 |
| Suzuki, E | 1 |
| Imoto, I | 1 |
| Kasugai, Y | 1 |
| Oze, I | 1 |
| Ugai, T | 1 |
| Iwase, M | 1 |
| Usui, Y | 1 |
| Kawakatsu, Y | 1 |
| Sawabe, M | 1 |
| Hirayama, Y | 1 |
| Tanaka, T | 1 |
| Abe, T | 1 |
| Ito, S | 1 |
| Komori, K | 1 |
| Hanai, N | 1 |
| Tajika, M | 1 |
| Shimizu, Y | 1 |
| Niwa, Y | 1 |
| Ito, H | 1 |
| Matsuo, K | 1 |
| Marttila, E | 1 |
| Rusanen, P | 1 |
| Uittamo, J | 1 |
| Salaspuro, M | 1 |
| Rautemaa-Richardson, R | 1 |
| Salo, T | 1 |
| Mizumoto, A | 1 |
| Ohashi, S | 1 |
| Hirohashi, K | 1 |
| Amanuma, Y | 1 |
| Matsuda, T | 1 |
| Muto, M | 1 |
| Saad, MA | 1 |
| Kuo, SZ | 1 |
| Rahimy, E | 1 |
| Zou, AE | 1 |
| Korrapati, A | 1 |
| Rahimy, M | 1 |
| Kim, E | 1 |
| Zheng, H | 1 |
| Yu, MA | 1 |
| Wang-Rodriguez, J | 1 |
| Ongkeko, WM | 1 |
| Brennan, P | 1 |
| Yokoyama, A | 2 |
| Omori, T | 1 |
| McGregor, NR | 1 |
| Seitz, HK | 1 |
| Matsuzaki, S | 1 |
| Homann, N | 1 |
| Väkeväinen, S | 1 |
| Wang, XD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| W.I.S.E.-Wine Implementation for Surgical Recovery Enhancement[NCT05261620] | 132 participants (Anticipated) | Interventional | 2022-12-12 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for acetaldehyde and Head and Neck Neoplasms
| Article | Year |
|---|---|
Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium.
Topics: Acetaldehyde; Animals; Carcinogenesis; Carcinoma, Squamous Cell; DNA Damage; Esophageal Neoplasms; E | 2017 |
Genetic polymorphisms of alcohol and aldehyde dehydrogenases and risk for esophageal and head and neck cancers.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Carcinogens; | 2005 |
Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Aldehyd | 2007 |
Alcohol and cancer.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mit | 2001 |
5 other studies available for acetaldehyde and Head and Neck Neoplasms
| Article | Year |
|---|---|
Usefulness of the aldehyde breath test for predicting metachronous recurrence in patients with esophageal squamous cell carcinoma and hypopharyngeal squamous cell carcinoma.
Topics: Acetaldehyde; Aldehydes; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Ethanol; Head and | 2023 |
Across-Site Differences in the Mechanism of Alcohol-Induced Digestive Tract Carcinogenesis: An Evaluation by Mediation Analysis.
Topics: Acetaldehyde; Adult; Aged; Alcohol Drinking; Aldehyde Dehydrogenase, Mitochondrial; Carcinogenesis; | 2020 |
Expression of p53 is associated with microbial acetaldehyde production in oralsquamous cell carcinoma.
Topics: Acetaldehyde; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Mouth Neoplasms; Tumor Supp | 2021 |
Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma.
Topics: Acetaldehyde; Adult; Alcohols; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Prolifera | 2015 |
Commentary: Mendelian randomization and gene-environment interaction.
Topics: Acetaldehyde; Alcohol Drinking; Behavior; Causality; Diet; Environment; Genetic Predisposition to Di | 2004 |