acetaldehyde has been researched along with Experimental Neoplasms in 15 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alcohol consumption is the key risk factor for the development of esophageal squamous cell carcinoma (ESCC), and acetaldehyde, a metabolite of alcohol, is an alcohol-derived major carcinogen that causes DNA damage." | 3.96 | Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2 (Glu504Lys) knock-in mice. ( Amanuma, Y; Baba, K; Hirohashi, K; Ida, T; Kikuchi, O; Matsubara, J; Matsuda, T; Mitani, Y; Miyamoto, S; Mizumoto, A; Muto, M; Nakai, Y; Ohashi, S; Seno, H; Yamada, A; Yamamoto, Y, 2020) |
| "Formaldehyde was recovered at a level of 1356 +/- 234 nmol/kg0." | 1.28 | Analysis of reactive carbonyls in the expired air of transgenic mice. ( Clifford, AJ; Ebeler, SE; Hinrichs, SH; Shibamoto, T, 1992) |
| "The toxic effects of ethanol and acetaldehyde on testosterone biosynthesis were examined in vitro using isolated Leydig cells prepared from adult rat testes." | 1.27 | Inhibition of testosterone production by rat Leydig cells with ethanol and acetaldehyde: prevention of ethanol toxicity with 4-methylpyrazole. ( Graham, TJ; Santucci, L; Van Thiel, DH, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hirohashi, K | 1 |
| Ohashi, S | 1 |
| Amanuma, Y | 1 |
| Nakai, Y | 1 |
| Ida, T | 1 |
| Baba, K | 1 |
| Mitani, Y | 1 |
| Mizumoto, A | 1 |
| Yamamoto, Y | 1 |
| Kikuchi, O | 1 |
| Matsubara, J | 1 |
| Yamada, A | 1 |
| Miyamoto, S | 1 |
| Seno, H | 1 |
| Matsuda, T | 1 |
| Muto, M | 1 |
| WATANABE, F | 1 |
| SUGIMOTO, S | 1 |
| Hansen, RJ | 1 |
| Ludeman, SM | 1 |
| Paikoff, SJ | 1 |
| Pegg, AE | 1 |
| Dolan, ME | 1 |
| Reuzel, PG | 1 |
| Feron, VJ | 3 |
| Spit, BJ | 1 |
| Beems, RB | 1 |
| Kroes, R | 1 |
| Santucci, L | 1 |
| Graham, TJ | 1 |
| Van Thiel, DH | 1 |
| Toth, B | 2 |
| Smith, JW | 1 |
| Patil, KD | 1 |
| Patil, K | 1 |
| Kruysse, A | 1 |
| Woutersen, RA | 1 |
| Cederbaum, AI | 1 |
| Rubin, E | 1 |
| Ebeler, SE | 1 |
| Hinrichs, SH | 1 |
| Clifford, AJ | 1 |
| Shibamoto, T | 1 |
| Van Duuren, BL | 1 |
| Seidman, I | 1 |
| Melchionne, S | 1 |
| Kline, SA | 1 |
| Norpoth, K | 2 |
| Heger, M | 2 |
| Müller, G | 2 |
| Mohtashamipur, E | 2 |
| Kemena, A | 2 |
| Witting, C | 2 |
1 review available for acetaldehyde and Experimental Neoplasms
| Article | Year |
|---|---|
Acetaldehyde.
Topics: Acetaldehyde; Animals; Carcinogenicity Tests; Carcinogens; Humans; Mutagenicity Tests; Mutagens; Neo | 1999 |
14 other studies available for acetaldehyde and Experimental Neoplasms
| Article | Year |
|---|---|
Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2 (Glu504Lys) knock-in mice.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase, Mitochondrial; Animals; Benzamides; Benzodio | 2020 |
[Study on the carcinogenicity of aldehyde. 3. Four cases of sarcomas of rats appearing in the areas of repeated subcutaneous injections of acetaldehyde].
Topics: Acetaldehyde; Animals; Injections, Subcutaneous; Neoplasms, Experimental; Rats; Sarcoma | 1956 |
Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals.
Topics: Acetaldehyde; Acrolein; Alkylating Agents; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclophospham | 2007 |
Tissue damage and nutritional factors in experimental respiratory tract (Co-)carcinogenesis.
Topics: Acetaldehyde; Animals; Benzo(a)pyrene; Benzopyrenes; Cocarcinogenesis; Cricetinae; Glass; Neoplasms, | 1983 |
Inhibition of testosterone production by rat Leydig cells with ethanol and acetaldehyde: prevention of ethanol toxicity with 4-methylpyrazole.
Topics: Acetaldehyde; Animals; Cell Line; Depression, Chemical; Ethanol; Fomepizole; In Vitro Techniques; Le | 1983 |
Cancer induction in mice with acetaldehyde methylformylhydrazone of the false morel mushroom.
Topics: Acetaldehyde; Animals; Basidiomycota; Female; Male; Mice; Mycotoxins; Neoplasms, Experimental | 1981 |
Gyromitrin as a tumor inducer.
Topics: Acetaldehyde; Adenocarcinoma; Adenoma; Animals; Basidiomycota; Carcinogens; Carcinoma, Squamous Cell | 1981 |
Respiratory tract tumours in hamsters exposed to acetaldehyde vapour alone or simultaneously to benzo(a)pyrene or diethylnitrosamine.
Topics: Acetaldehyde; Aerosols; Animals; Benzopyrenes; Body Weight; Carcinoma; Cricetinae; Diethylnitrosamin | 1982 |
Effects of exposure to acetaldehyde in syrian hamsters simultaneously treated with benzo(a)pyrene or diethylnitrosamine.
Topics: Acetaldehyde; Animals; Benzopyrenes; Body Weight; Cocarcinogenesis; Cricetinae; Diethylnitrosamine; | 1979 |
The oxidation of acetaldehyde by isolated mitochondria from various organs of the rat and hepatocellular carcinoma.
Topics: Acetaldehyde; Adenosine Diphosphate; Animals; Antimycin A; Atractyloside; Carcinoma; Citrates; Dinit | 1977 |
Analysis of reactive carbonyls in the expired air of transgenic mice.
Topics: Acetaldehyde; Acetone; Animals; Breath Tests; Chromatography, Gas; Formaldehyde; Gas Chromatography- | 1992 |
Carcinogenicity bioassays of bromoacetaldehyde and bromoethanol--potential metabolites of dibromoethane.
Topics: Acetaldehyde; Animals; Biological Assay; Biotransformation; Body Weight; Carcinogens; Drug Administr | 1985 |
Investigations on metabolism and carcinogenicity of 1,1,2-trichloroethane.
Topics: Acetaldehyde; Animals; DNA; Female; Hydrocarbons, Chlorinated; Male; Neoplasms, Experimental; Rats; | 1988 |
Investigations on metabolism, genotoxic effects and carcinogenicity of 2,2'-dichlorodiethylether.
Topics: Acetaldehyde; Animals; Carcinogens; DNA; Dose-Response Relationship, Drug; Ether; Ethyl Ethers; Fema | 1986 |