Page last updated: 2024-10-16

acetaldehyde and Colorectal Cancer

acetaldehyde has been researched along with Colorectal Cancer in 11 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Research Excerpts

ExcerptRelevanceReference
" The presentations were (1) Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotype and cancer risk for upper aerodigestive tract in Japanese alcoholics, by Akira Yokoyama; (2) The role of acetaldehyde in alcohol-associated carcinogenesis, by Nils Homann; (3) High salivary acetaldehyde levels after a moderate dose of alcohol in ALDH2-deficient subjects, by Satu Väkeväinen; (4) Alcohol and vitamin A interactions, by Xian Dong Wang; and (5) Alcohol and colorectal cancer, by Helmut K."4.81Alcohol and cancer. ( Homann, N; Matsuzaki, S; Seitz, HK; Väkeväinen, S; Wang, XD; Yokoyama, A, 2001)
"Colorectal cancer (CRC) and pancreatic cancer are two very significant contributors to cancer-related deaths."2.52Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers. ( Arcaroli, J; Messersmith, W; Singh, S; Thompson, DC; Vasiliou, V, 2015)
"The pathogenesis of ethanol-related colorectal cancer (ER-CRC) is thought to be partly mediated by gut microbes."1.43Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer. ( Aoki, Y; Hattori, M; Inai, M; Kinoshita, K; Kuwahara, A; Mizukami, T; Morita, H; Nakayama, T; Oshima, K; Saito, Y; Shimoyama, T; Suda, W; Suga, S; Suwa, Y; Takahashi, S; Totsuka, Y; Tsubo, T; Tsuruya, A; Tsutsumi, E; Yamaguchi, H; Yokoyama, A, 2016)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Zhang, Y1
Zheng, DW1
Li, CX1
Pan, P1
Zeng, SM1
Pan, T1
Zhang, XZ1
Cerretelli, G1
Zhou, Y2
Müller, MF2
Adams, DJ2
Arends, MJ2
Crous-Bou, M1
Rennert, G1
Cuadras, D1
Salazar, R1
Cordero, D1
Saltz Rennert, H1
Lejbkowicz, F1
Kopelovich, L1
Monroe Lipkin, S1
Bernard Gruber, S1
Moreno, V1
Singh, S1
Arcaroli, J1
Thompson, DC1
Messersmith, W1
Vasiliou, V1
Tsuruya, A1
Kuwahara, A1
Saito, Y1
Yamaguchi, H1
Tsubo, T1
Suga, S1
Inai, M1
Aoki, Y1
Takahashi, S1
Tsutsumi, E1
Suwa, Y1
Morita, H1
Kinoshita, K1
Totsuka, Y1
Suda, W1
Oshima, K1
Hattori, M1
Mizukami, T1
Yokoyama, A2
Shimoyama, T1
Nakayama, T1
Shin, SY1
Ahn, S1
Yoon, H1
Jung, H1
Jung, Y1
Koh, D1
Lee, YH1
Lim, Y1
Homann, N2
König, IR1
Marks, M1
Benesova, M1
Stickel, F1
Millonig, G1
Mueller, S1
Seitz, HK2
Chiang, CP1
Jao, SW1
Lee, SP1
Chen, PC1
Chung, CC1
Lee, SL1
Nieh, S1
Yin, SJ1
Motrescu, ER1
Otto, AM1
Brischwein, M1
Zahler, S1
Wolf, B1
Matsuzaki, S1
Väkeväinen, S1
Wang, XD1

Reviews

2 reviews available for acetaldehyde and Colorectal Cancer

ArticleYear
Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers.
    Advances in experimental medicine and biology, 2015, Volume: 815

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Cell Proliferation; Colorectal Neoplasms; Humans; Pancreatic N

2015
Alcohol and cancer.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:5 Suppl IS

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mit

2001

Other Studies

9 other studies available for acetaldehyde and Colorectal Cancer

ArticleYear
Temulence Therapy to Orthotopic Colorectal Tumor via Oral Administration of Fungi-Based Acetaldehyde Generator.
    Small methods, 2022, Volume: 6, Issue:1

    Topics: Acetaldehyde; Administration, Oral; Alcohol Dehydrogenase; Animals; Colorectal Neoplasms; Saccharomy

2022
Acetaldehyde and defective mismatch repair increase colonic tumours in a Lynch syndrome model with Aldh1b1 inactivation.
    Disease models & mechanisms, 2023, 08-01, Volume: 16, Issue:8

    Topics: Acetaldehyde; Animals; Colonic Neoplasms; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Non

2023
Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenas

2013
Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer.
    Scientific reports, 2016, 06-13, Volume: 6

    Topics: Acetaldehyde; Adolescent; Adult; Aged; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase, Mi

2016
Colorectal anticancer activities of polymethoxylated 3-naphthyl-5-phenylpyrazoline-carbothioamides.
    Bioorganic & medicinal chemistry letters, 2016, 09-01, Volume: 26, Issue:17

    Topics: Acetaldehyde; Antineoplastic Agents; Cell Line; Cell Survival; Colorectal Neoplasms; Humans; Molecul

2016
Effects of long-term ethanol consumption and Aldh1b1 depletion on intestinal tumourigenesis in mice.
    The Journal of pathology, 2017, Volume: 241, Issue:5

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitoc

2017
Alcohol and colorectal cancer: the role of alcohol dehydrogenase 1C polymorphism.
    Alcoholism, clinical and experimental research, 2009, Volume: 33, Issue:3

    Topics: Acetaldehyde; Adenoma; Adult; Aged; Alcohol Dehydrogenase; Alcohol Drinking; Carcinoma; Colorectal N

2009
Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human large bowel: association of the functional polymorphisms of ADH and ALDH genes with hemorrhoids and colorectal cancer.
    Alcohol (Fayetteville, N.Y.), 2012, Volume: 46, Issue:1

    Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aldehyd

2012
Dynamic analysis of metabolic effects of chloroacetaldehyde and cytochalasin B on tumor cells using bioelectronic sensor chips.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:10

    Topics: Acetaldehyde; Adenocarcinoma; Biosensing Techniques; Cell Line, Tumor; Colorectal Neoplasms; Cytocha

2005