Page last updated: 2024-10-16

acetaldehyde and Chromosome-Defective Micronuclei

acetaldehyde has been researched along with Chromosome-Defective Micronuclei in 4 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Research Excerpts

ExcerptRelevanceReference
" Four suspected aneuploidy-inducing chemicals, acetaldehyde (AA), diethylstilbestrol (DES), diethylstilbestrol dipropionate (DESdp) and griseofulvin (GF), have been evaluated with the assay."3.69Detection of the centromere in micronuclei by fluorescence in situ hybridization: its application to the human lymphocyte micronucleus assay after treatment with four suspected aneugens. ( Cocchi, L; Migliore, L; Scarpato, R, 1996)
"The dose-response relationship for biomarkers of exposure (N(2)-ethylidene-dG adducts) and effect (cell survival and micronucleus formation) was determined across 4."1.39Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure. ( Bodnar, WM; Green, A; Moeller, BC; Recio, L; Sun, W; Swenberg, JA; Wright, FA, 2013)
"Four suspected aneuploidy-inducing chemicals, acetaldehyde (AA), diethylstilbestrol (DES), diethylstilbestrol dipropionate (DESdp) and griseofulvin (GF), have been evaluated with the assay."1.29Detection of the centromere in micronuclei by fluorescence in situ hybridization: its application to the human lymphocyte micronucleus assay after treatment with four suspected aneugens. ( Cocchi, L; Migliore, L; Scarpato, R, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moeller, BC1
Recio, L1
Green, A1
Sun, W1
Wright, FA1
Bodnar, WM1
Swenberg, JA1
Kim, JS1
Kim, YJ1
Kim, TY1
Song, JY1
Cho, YH1
Park, YC1
Chung, HW1
Kunugita, N1
Isse, T1
Oyama, T1
Kitagawa, K1
Ogawa, M1
Yamaguchi, T1
Kinaga, T1
Kawamoto, T1
Migliore, L1
Cocchi, L1
Scarpato, R1

Other Studies

4 other studies available for acetaldehyde and Chromosome-Defective Micronuclei

ArticleYear
Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 133, Issue:1

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Carbon Isotopes; Cell C

2013
Association of ALDH2 polymorphism with sensitivity to acetaldehyde-induced micronuclei and facial flushing after alcohol intake.
    Toxicology, 2005, Jun-01, Volume: 210, Issue:2-3

    Topics: Acetaldehyde; Adult; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial

2005
Increased frequencies of micronucleated reticulocytes and T-cell receptor mutation in Aldh2 knockout mice exposed to acetaldehyde.
    The Journal of toxicological sciences, 2008, Volume: 33, Issue:1

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Male; Mice; Mi

2008
Detection of the centromere in micronuclei by fluorescence in situ hybridization: its application to the human lymphocyte micronucleus assay after treatment with four suspected aneugens.
    Mutagenesis, 1996, Volume: 11, Issue:3

    Topics: Acetaldehyde; Aneuploidy; Centromere; Diethylstilbestrol; Drug Evaluation, Preclinical; Griseofulvin

1996