acetaldehyde has been researched along with Cell Transformation, Neoplastic in 12 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Taken together with somatic breast cancer genome data, these results point to a breakdown in a BRCA/FA-mSWI/SNF-ΔNP63-mediated DNA repair and differentiation maintenance process in mammary epithelial cells that may contribute to sporadic breast cancer development." | 1.43 | BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells. ( Bierie, B; Dimitrov, SD; Feunteun, J; Gelman, R; Giobbie-Hurder, A; Li, AG; Liu, B; Livingston, DM; Pathania, S; Polyak, K; Toomire, K; Wang, H, 2016) |
| " First, to determine the optimal concentration of AA for detecting N(2)-ethylidene-dG in cell culture, a dose-response study was performed using HL60 cells of the human promyelocytic leukemia cell line." | 1.38 | Stability of acetaldehyde-derived DNA adduct in vitro. ( Chiba, T; Hori, K; Matsuda, T; Miyamoto, S; Muto, M; Yukawa, Y, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sobh, A | 1 |
| Loguinov, A | 1 |
| Stornetta, A | 1 |
| Balbo, S | 1 |
| Tagmount, A | 1 |
| Zhang, L | 1 |
| Vulpe, CD | 1 |
| Tao, L | 2 |
| Pavlova, SI | 1 |
| Gasparovich, SR | 1 |
| Jin, L | 1 |
| Schwartz, J | 2 |
| Wang, H | 1 |
| Bierie, B | 1 |
| Li, AG | 1 |
| Pathania, S | 1 |
| Toomire, K | 1 |
| Dimitrov, SD | 1 |
| Liu, B | 1 |
| Gelman, R | 1 |
| Giobbie-Hurder, A | 1 |
| Feunteun, J | 1 |
| Polyak, K | 1 |
| Livingston, DM | 1 |
| McKillop, IH | 1 |
| Schrum, LW | 1 |
| Pavlova, S | 1 |
| Kolokythas, A | 1 |
| Lugakingira, M | 1 |
| Miloro, M | 1 |
| Hori, K | 1 |
| Miyamoto, S | 1 |
| Yukawa, Y | 1 |
| Muto, M | 1 |
| Chiba, T | 1 |
| Matsuda, T | 1 |
| Seitz, HK | 1 |
| Stickel, F | 1 |
| Nakajima, M | 1 |
| Kato, J | 1 |
| Kohgo, Y | 1 |
| Katsuki, S | 1 |
| Inui, N | 1 |
| Ohya, M | 1 |
| Takeichi, N | 1 |
| Niitu, Y | 1 |
| Dhalluin, S | 1 |
| Elias, Z | 1 |
| Poirot, O | 1 |
| Gate, L | 1 |
| Pages, N | 1 |
| Tapiero, H | 1 |
| Vasseur, P | 1 |
| Nguyen-Ba, G | 1 |
| Błasiak, J | 1 |
| Huberman, E | 1 |
| Bartsch, H | 1 |
| Sachs, L | 1 |
| Eker, P | 1 |
| Sanner, T | 1 |
2 reviews available for acetaldehyde and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Role of alcohol in liver carcinogenesis.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; | 2009 |
Molecular mechanisms of alcohol-mediated carcinogenesis.
Topics: Acetaldehyde; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA Methylation; Ethanol; Human | 2007 |
10 other studies available for acetaldehyde and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Genome-Wide CRISPR Screening Identifies the Tumor Suppressor Candidate OVCA2 As a Determinant of Tolerance to Acetaldehyde.
Topics: Acetaldehyde; Cell Survival; Cell Transformation, Neoplastic; CRISPR-Cas Systems; DNA Adducts; Dose- | 2019 |
Alcohol metabolism by oral streptococci and interaction with human papillomavirus leads to malignant transformation of oral keratinocytes.
Topics: Acetaldehyde; Bacterial Adhesion; Cell Transformation, Neoplastic; Ethanol; Human papillomavirus 16; | 2015 |
BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.
Topics: Acetaldehyde; BRCA1 Protein; Breast Neoplasms; Cell Differentiation; Cell Line; Cell Transformation, | 2016 |
Streptococci-human papilloma virus interaction with ethanol exposure leads to keratinocyte damage.
Topics: Acetaldehyde; Antimetabolites; Bacterial Adhesion; Basement Membrane; Bromodeoxyuridine; Carcinogens | 2012 |
Stability of acetaldehyde-derived DNA adduct in vitro.
Topics: Acetaldehyde; Carcinogens; Cell Culture Techniques; Cell Transformation, Neoplastic; Deoxyguanosine; | 2012 |
Abnormal ethanol metabolism in Long-Evans Cinnamon rats, a mutant strain developing spontaneous hepatoma.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Animals; Cell Transformatio | 1993 |
Apoptosis inhibition and ornithine decarboxylase superinduction as early epigenetic events in morphological transformation of Syrian hamster embryo cells exposed to 2-methoxyacetaldehyde, a metabolite of 2-methoxyethanol.
Topics: Acetaldehyde; Animals; Apoptosis; bcl-X Protein; Carcinogenicity Tests; Cell Transformation, Neoplas | 1999 |
Ethanol and acetaldehyde impair the repair of bleomycin-damaged DNA in human lymphocytes.
Topics: Acetaldehyde; Antimetabolites, Antineoplastic; Bleomycin; Cell Transformation, Neoplastic; Comet Ass | 2001 |
Mutation induction in Chinese hamster V79 cells by two vinyl chloride metabolites, chloroethylene oxide and 2-chloroacetaldehyde.
Topics: Acetaldehyde; Animals; Azaguanine; Cell Line; Cell Transformation, Neoplastic; Chemical Phenomena; C | 1975 |
Initiation of in vitro cell transformation by formaldehyde and acetaldehyde as measured by attachment-independent survival of cells in aggregates.
Topics: Acetaldehyde; Animals; Cell Aggregation; Cell Line; Cell Survival; Cell Transformation, Neoplastic; | 1986 |