acetaldehyde has been researched along with Cardiomegaly in 3 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic alcoholism leads to the onset and progression of alcoholic cardiomyopathy through toxic mechanisms of ethanol and its metabolite, acetaldehyde." | 3.75 | Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. ( Doser, TA; Epstein, PN; Li, SY; Ren, J; Thomas, DP; Turdi, S, 2009) |
| "Chronic alcohol consumption led to cardiac hypertrophy, reduced fractional shortening, cell shortening, and impaired intracellular Ca(2+) homeostasis, the effect of which was alleviated by ALDH2." | 1.35 | Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. ( Doser, TA; Epstein, PN; Li, SY; Ren, J; Thomas, DP; Turdi, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doser, TA | 1 |
| Turdi, S | 1 |
| Thomas, DP | 1 |
| Epstein, PN | 2 |
| Li, SY | 1 |
| Ren, J | 1 |
| WAKO, H | 1 |
| Liang, Q | 1 |
| Carlson, EC | 1 |
| Borgerding, AJ | 1 |
3 other studies available for acetaldehyde and Cardiomegaly
| Article | Year |
|---|---|
Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Ca | 2009 |
Pyruvic acid and heart enlarging; and acetaldehyde, preliminary report.
Topics: Acetaldehyde; Beriberi; Cardiomegaly; Heart; Pyruvates; Pyruvic Acid | 1951 |
A transgenic model of acetaldehyde overproduction accelerates alcohol cardiomyopathy.
Topics: Acetaldehyde; Actins; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cardiomyopathy, Alcoholic; D | 1999 |