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acetaldehyde and Cardiac Hypertrophy

acetaldehyde has been researched along with Cardiac Hypertrophy in 3 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
"Chronic alcoholism leads to the onset and progression of alcoholic cardiomyopathy through toxic mechanisms of ethanol and its metabolite, acetaldehyde."3.75Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. ( Doser, TA; Epstein, PN; Li, SY; Ren, J; Thomas, DP; Turdi, S, 2009)
"Chronic alcohol consumption led to cardiac hypertrophy, reduced fractional shortening, cell shortening, and impaired intracellular Ca(2+) homeostasis, the effect of which was alleviated by ALDH2."1.35Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. ( Doser, TA; Epstein, PN; Li, SY; Ren, J; Thomas, DP; Turdi, S, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doser, TA1
Turdi, S1
Thomas, DP1
Epstein, PN2
Li, SY1
Ren, J1
WAKO, H1
Liang, Q1
Carlson, EC1
Borgerding, AJ1

Other Studies

3 other studies available for acetaldehyde and Cardiac Hypertrophy

ArticleYear
Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction.
    Circulation, 2009, Apr-14, Volume: 119, Issue:14

    Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Ca

2009
Pyruvic acid and heart enlarging; and acetaldehyde, preliminary report.
    The Tohoku journal of experimental medicine, 1951, Volume: 55, Issue:1

    Topics: Acetaldehyde; Beriberi; Cardiomegaly; Heart; Pyruvates; Pyruvic Acid

1951
A transgenic model of acetaldehyde overproduction accelerates alcohol cardiomyopathy.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Acetaldehyde; Actins; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cardiomyopathy, Alcoholic; D

1999