acetaldehyde has been researched along with Cancer of Gastrointestinal Tract in 18 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Strong epidemiological, genetic and biochemical evidence indicates that local acetaldehyde exposure is a major factor behind gastrointestinal cancers especially associated with alcohol drinking and smoking." | 4.84 | Pharmacological treatments and strategies for reducing oral and intestinal acetaldehyde. ( Salaspuro, V, 2007) |
| "Acetaldehyde has been classified as a carcinogen in experimental animal research." | 2.44 | The role of acetaldehyde in alcohol-associated cancer of the gastrointestinal tract. ( Homann, N; Seitz, HK, 2007) |
| "Acetaldehyde was analyzed from salivary samples gas chromatographically at 0, 5, and 10 minutes from the beginning of the smoking." | 1.33 | Eliminating carcinogenic acetaldehyde by cysteine from saliva during smoking. ( Hietala, JM; Marvola, ML; Salaspuro, MP; Salaspuro, VJ, 2006) |
| "Acetaldehyde has been shown to dissolve into the saliva during smoking and to be a local carcinogen in the human upper digestive tract." | 1.33 | Eliminating carcinogenic acetaldehyde by cysteine from saliva during smoking. ( Hietala, JM; Marvola, ML; Salaspuro, MP; Salaspuro, VJ, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Y | 1 |
| Liang, Q | 1 |
| Chen, Y | 1 |
| Cao, Y | 1 |
| Zhuo, Q | 1 |
| Liu, B | 1 |
| Wang, S | 1 |
| Koyanagi, YN | 1 |
| Suzuki, E | 1 |
| Imoto, I | 1 |
| Kasugai, Y | 1 |
| Oze, I | 1 |
| Ugai, T | 1 |
| Iwase, M | 1 |
| Usui, Y | 1 |
| Kawakatsu, Y | 1 |
| Sawabe, M | 1 |
| Hirayama, Y | 1 |
| Tanaka, T | 1 |
| Abe, T | 1 |
| Ito, S | 1 |
| Komori, K | 1 |
| Hanai, N | 1 |
| Tajika, M | 1 |
| Shimizu, Y | 1 |
| Niwa, Y | 1 |
| Ito, H | 1 |
| Matsuo, K | 1 |
| Salaspuro, M | 7 |
| Yokoyama, A | 1 |
| Tsutsumi, E | 1 |
| Imazeki, H | 1 |
| Suwa, Y | 1 |
| Nakamura, C | 1 |
| Mizukami, T | 1 |
| Yokoyama, T | 1 |
| Juliano, C | 1 |
| Cossu, M | 1 |
| Rota, MT | 2 |
| Satta, D | 1 |
| Poggi, P | 2 |
| Giunchedi, P | 1 |
| Mikko, S | 1 |
| Haas, SL | 1 |
| Ye, W | 1 |
| Löhr, JM | 1 |
| Väkeväinen, S | 1 |
| Salaspuro, V | 3 |
| Salaspuro, VJ | 1 |
| Hietala, JM | 1 |
| Marvola, ML | 1 |
| Salaspuro, MP | 1 |
| Seitz, HK | 3 |
| Meier, P | 1 |
| Homann, N | 1 |
| Oneta, CM | 1 |
| Hietala, J | 1 |
| Kaihovaara, P | 1 |
| Pihlajarinne, L | 1 |
| Marvola, M | 1 |
9 reviews available for acetaldehyde and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Key role of local acetaldehyde in upper GI tract carcinogenesis.
Topics: Acetaldehyde; Carcinogenesis; Ethanol; Gastrointestinal Neoplasms; Humans | 2017 |
Acetaldehyde and gastric cancer.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Ethanol; Gastrointestinal Neoplasms; Hu | 2011 |
Interactions of alcohol and tobacco in gastrointestinal cancer.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenas | 2012 |
Alcohol consumption and digestive tract cancer.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; DNA; Ethanol; Gastrointestinal Neoplasms; Gastrointestin | 2012 |
[Acetaldehyde as a cause of gastrointestinal cancer].
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Anima | 2003 |
The role of acetaldehyde in upper digestive tract cancer in alcoholics.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mit | 2007 |
The role of acetaldehyde in alcohol-associated cancer of the gastrointestinal tract.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Carci | 2007 |
Pharmacological treatments and strategies for reducing oral and intestinal acetaldehyde.
Topics: Acetaldehyde; Alcohol Drinking; Bacteria; Chlorhexidine; Ciprofloxacin; Cysteine; Gastrointestinal N | 2007 |
Gastrointestinal alcohol dehydrogenase.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Carcinogens; Digestive System; Ethanol; Gastrointestin | 1998 |
2 trials available for acetaldehyde and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Salivary acetaldehyde concentration according to alcoholic beverage consumed and aldehyde dehydrogenase-2 genotype.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial | 2008 |
Removal of acetaldehyde from saliva by a slow-release buccal tablet of L-cysteine.
Topics: Acetaldehyde; Adult; Area Under Curve; Carcinogens; Cysteine; Gastrointestinal Neoplasms; Humans; Ma | 2002 |
7 other studies available for acetaldehyde and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Aldehyde dehydrogenase 2 gene rs671 G>A polymorphism is associated with an increased risk of digestive tract cancer.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase, Mitochondrial; Gastrointestinal Neoplasms; G | 2023 |
Across-Site Differences in the Mechanism of Alcohol-Induced Digestive Tract Carcinogenesis: An Evaluation by Mediation Analysis.
Topics: Acetaldehyde; Adult; Aged; Alcohol Drinking; Aldehyde Dehydrogenase, Mitochondrial; Carcinogenesis; | 2020 |
Acetaldehyde as a common denominator and cumulative carcinogen in digestive tract cancers.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Environmental | 2009 |
Buccal tablets containing cysteine and chlorhexidine for the reduction of acetaldehyde levels in the oral cavity.
Topics: Acetaldehyde; Alcohol Drinking; Bacteria; Chlorhexidine; Cysteine; Drug Therapy, Combination; Ethano | 2011 |
Reduction of oral acetaldehyde levels using a controlled-release chlorhexidine chip as a prevention strategy against upper digestive tract cancer.
Topics: Acetaldehyde; Alcohol Drinking; Chlorhexidine; Delayed-Action Preparations; Feasibility Studies; Gas | 2003 |
Synergistic effect of alcohol drinking and smoking on in vivo acetaldehyde concentration in saliva.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Central Nervous System Depressants; Ethanol; Female; Gastroin | 2004 |
Eliminating carcinogenic acetaldehyde by cysteine from saliva during smoking.
Topics: Acetaldehyde; Adult; Cysteine; Dose-Response Relationship, Drug; Female; Gastrointestinal Neoplasms; | 2006 |