acetaldehyde has been researched along with Bronchial Hyperreactivity in 8 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bronchial responsiveness to acetaldehyde, a main factor in alcohol-induced bronchoconstriction, and methacholine were compared between 10 subjects with alcohol-induced bronchoconstriction and 16 asthmatic subjects without alcohol sensitivity." | 9.09 | Increased airway responsiveness to acetaldehyde in asthmatic subjects with alcohol-induced bronchoconstriction. ( Fujimura, M; Hashimoto, T; Ishiura, Y; Iwasa, K; Kamio, Y; Matsuda, T; Myou, S, 1999) |
| "Although airway hyperresponsiveness to inhaled acetaldehyde has been documented in Japanese patients with asthma, the response to this bronchoconstrictor agent has never been studied in Caucasians." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The objectives of the study were to determine differences in airway responsiveness to acetaldehyde between asthmatic and healthy subjects, and to examine the relationship between acetaldehyde responsiveness and the variability of peak expiratory flow (PEF)." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The response to methacholine and acetaldehyde challenges was measured in 81 non-smoking adults (61 asthmatics and 20 normal controls)." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The two types of challenge yielded a similarly high level of sensitivity (100% for methacholine and 92% for acetaldehyde) and specificity (90 and 100%, respectively) to distinguish between asthma and controls." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "These results indicate that airway hyperresponsiveness to acetaldehyde is a sensitive and specific indicator for separating asthmatic and normal subjects." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "We previously reported that inhaled acetaldehyde, a metabolite of ethanol and a main factor in alcohol-induced asthma, causes bronchoconstriction indirectly through endogenously released histamine in asthmatic subjects." | 9.08 | Repeated inhalation challenge with exogenous and endogenous histamine released by acetaldehyde inhalation in asthmatic patients. ( Bando, T; Fujimura, M; Kamio, Y; Matsuda, T; Myou, S; Nakatsumi, Y, 1995) |
| "Acetaldehyde induces bronchial hyperresponsiveness in patients with asthma by mechanisms other than histamine release." | 9.07 | Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects. ( Fujimura, M; Matsuda, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
| "Asthmatic subjects have an exaggerated airway response to inhaled acetaldehyde, but no information is available on airway responsiveness to this bronchoconstrictor agent in subjects with allergic rhinitis." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "The aim of this study was to determine the effect of inhaled acetaldehyde on lung function in nonasthmatic subjects with allergic rhinitis." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "A total of 78 adults (43 subjects with allergic rhinitis, 16 asthmatics and 19 healthy subjects) were challenged with increased concentrations of acetaldehyde and methacholine." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "The geometric mean PC(20) acetaldehyde value for asthmatics was 35." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "We conclude that subjects with allergic rhinitis are less responsive to inhaled acetaldehyde than asthmatic subjects, but more than healthy controls." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "Inhaled acetaldehyde may induce bronchoconstriction in asthmatic subjects and provides a new method to investigate airway responsiveness." | 7.70 | Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis. ( Marín, J; Millan, M; Pérez, JA; Peris, R; Prieto, L; Sánchez-Toril, F, 2000) |
| "Bronchial responsiveness to acetaldehyde, a main factor in alcohol-induced bronchoconstriction, and methacholine were compared between 10 subjects with alcohol-induced bronchoconstriction and 16 asthmatic subjects without alcohol sensitivity." | 5.09 | Increased airway responsiveness to acetaldehyde in asthmatic subjects with alcohol-induced bronchoconstriction. ( Fujimura, M; Hashimoto, T; Ishiura, Y; Iwasa, K; Kamio, Y; Matsuda, T; Myou, S, 1999) |
| "Although airway hyperresponsiveness to inhaled acetaldehyde has been documented in Japanese patients with asthma, the response to this bronchoconstrictor agent has never been studied in Caucasians." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The objectives of the study were to determine differences in airway responsiveness to acetaldehyde between asthmatic and healthy subjects, and to examine the relationship between acetaldehyde responsiveness and the variability of peak expiratory flow (PEF)." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The response to methacholine and acetaldehyde challenges was measured in 81 non-smoking adults (61 asthmatics and 20 normal controls)." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The two types of challenge yielded a similarly high level of sensitivity (100% for methacholine and 92% for acetaldehyde) and specificity (90 and 100%, respectively) to distinguish between asthma and controls." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "These results indicate that airway hyperresponsiveness to acetaldehyde is a sensitive and specific indicator for separating asthmatic and normal subjects." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "We previously reported that inhaled acetaldehyde, a metabolite of ethanol and a main factor in alcohol-induced asthma, causes bronchoconstriction indirectly through endogenously released histamine in asthmatic subjects." | 5.08 | Repeated inhalation challenge with exogenous and endogenous histamine released by acetaldehyde inhalation in asthmatic patients. ( Bando, T; Fujimura, M; Kamio, Y; Matsuda, T; Myou, S; Nakatsumi, Y, 1995) |
| "Acetaldehyde induces bronchial hyperresponsiveness in patients with asthma by mechanisms other than histamine release." | 5.07 | Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects. ( Fujimura, M; Matsuda, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
| "Asthmatic subjects have an exaggerated airway response to inhaled acetaldehyde, but no information is available on airway responsiveness to this bronchoconstrictor agent in subjects with allergic rhinitis." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "The aim of this study was to determine the effect of inhaled acetaldehyde on lung function in nonasthmatic subjects with allergic rhinitis." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "A total of 78 adults (43 subjects with allergic rhinitis, 16 asthmatics and 19 healthy subjects) were challenged with increased concentrations of acetaldehyde and methacholine." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "The geometric mean PC(20) acetaldehyde value for asthmatics was 35." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "We conclude that subjects with allergic rhinitis are less responsive to inhaled acetaldehyde than asthmatic subjects, but more than healthy controls." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "Inhaled acetaldehyde may induce bronchoconstriction in asthmatic subjects and provides a new method to investigate airway responsiveness." | 3.70 | Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis. ( Marín, J; Millan, M; Pérez, JA; Peris, R; Prieto, L; Sánchez-Toril, F, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lacroix, G | 1 |
| Tissot, S | 1 |
| Rogerieux, F | 1 |
| Beaulieu, R | 1 |
| Cornu, L | 1 |
| Gillet, C | 1 |
| Robidel, F | 1 |
| Lefèvre, JP | 1 |
| Bois, FY | 1 |
| Myou, S | 4 |
| Fujimura, M | 4 |
| Kamio, Y | 2 |
| Bando, T | 1 |
| Nakatsumi, Y | 1 |
| Matsuda, T | 4 |
| Nishi, K | 1 |
| Matsuda, M | 1 |
| Ohka, T | 1 |
| Amemiya, T | 1 |
| Tachibana, H | 1 |
| Kita, T | 1 |
| Ishiura, Y | 1 |
| Iwasa, K | 1 |
| Hashimoto, T | 1 |
| Prieto, L | 3 |
| Sánchez-Toril, F | 3 |
| Brotons, B | 1 |
| Soriano, S | 1 |
| Casañ, R | 1 |
| Belenguer, JL | 1 |
| Peris, R | 1 |
| Pérez, JA | 1 |
| Millan, M | 1 |
| Marín, J | 1 |
| Gutiérrez, V | 1 |
| Marín, MJ | 1 |
4 trials available for acetaldehyde and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Repeated inhalation challenge with exogenous and endogenous histamine released by acetaldehyde inhalation in asthmatic patients.
Topics: Acetaldehyde; Administration, Inhalation; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial | 1995 |
Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects.
Topics: Acetaldehyde; Adult; Aged; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; | 1994 |
Increased airway responsiveness to acetaldehyde in asthmatic subjects with alcohol-induced bronchoconstriction.
Topics: Acetaldehyde; Administration, Inhalation; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial | 1999 |
Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation.
Topics: Acetaldehyde; Adult; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tes | 2000 |
4 other studies available for acetaldehyde and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Decrease in ovalbumin-induced pulmonary allergic response by benzaldehyde but not acetaldehyde exposure in a Guinea pig model.
Topics: Acetaldehyde; Administration, Inhalation; Air Pollutants; Animals; Benzaldehydes; Bronchial Hyperrea | 2002 |
Peptide leukotrienes mediate acetaldehyde-induced bronchial hyper-responsiveness in guinea-pigs.
Topics: Acetaldehyde; Animals; Anti-Allergic Agents; Bronchial Hyperreactivity; Bronchial Provocation Tests; | 1997 |
Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis.
Topics: Acetaldehyde; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bro | 2000 |
Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness.
Topics: Acetaldehyde; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstric | 2002 |