acetaldehyde has been researched along with Asthma, Bronchial in 23 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetaldehyde is thought to be a main factor of alcohol-induced asthma." | 9.10 | Effect of ozagrel hydrochloride, a thromboxane synthetase inhibitor, on alcoholic beverage-induced bronchoconstriction in asthmatic patients. ( Fujimura, M; Ishiura, Y; Kita, T; Kurashima, K; Myou, S; Nakao, S; Nishi, K; Tachibana, H, 2002) |
| "Although airway hyperresponsiveness to inhaled acetaldehyde has been documented in Japanese patients with asthma, the response to this bronchoconstrictor agent has never been studied in Caucasians." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "These results indicate that airway hyperresponsiveness to acetaldehyde is a sensitive and specific indicator for separating asthmatic and normal subjects." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The objectives of the study were to determine differences in airway responsiveness to acetaldehyde between asthmatic and healthy subjects, and to examine the relationship between acetaldehyde responsiveness and the variability of peak expiratory flow (PEF)." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The two types of challenge yielded a similarly high level of sensitivity (100% for methacholine and 92% for acetaldehyde) and specificity (90 and 100%, respectively) to distinguish between asthma and controls." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The response to methacholine and acetaldehyde challenges was measured in 81 non-smoking adults (61 asthmatics and 20 normal controls)." | 9.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "Bronchial responsiveness to acetaldehyde, a main factor in alcohol-induced bronchoconstriction, and methacholine were compared between 10 subjects with alcohol-induced bronchoconstriction and 16 asthmatic subjects without alcohol sensitivity." | 9.09 | Increased airway responsiveness to acetaldehyde in asthmatic subjects with alcohol-induced bronchoconstriction. ( Fujimura, M; Hashimoto, T; Ishiura, Y; Iwasa, K; Kamio, Y; Matsuda, T; Myou, S, 1999) |
| "Acetaldehyde is a main factor of alcohol-induced asthma." | 9.09 | Effect of a cysteinyl leukotriene antagonist, pranlukast hydrate, on acetaldehyde-induced bronchoconstriction in asthmatic patients. ( Abo, M; Fujimura, M; Hashimoto, T; Kamio, Y; Katayama, N; Kita, T; Myou, S; Nakao, S; Nishitsuji, M; Nomura, S; Yoshimi, Y, 2001) |
| "We previously reported that inhaled acetaldehyde, a metabolite of ethanol and a main factor in alcohol-induced asthma, causes bronchoconstriction indirectly through endogenously released histamine in asthmatic subjects." | 9.08 | Repeated inhalation challenge with exogenous and endogenous histamine released by acetaldehyde inhalation in asthmatic patients. ( Bando, T; Fujimura, M; Kamio, Y; Matsuda, T; Myou, S; Nakatsumi, Y, 1995) |
| "Acetaldehyde, a main factor in alcohol-induced asthma, causes bronchoconstriction indirectly through histamine release; and tachyphylaxis in response to repeated inhalation of acetaldehyde is observed in patients with asthma." | 9.08 | Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma. ( Fujimura, M; Kamio, Y; Matsuda, T; Myou, S, 1997) |
| "We investigated the bronchial response to inhaled acetaldehyde in 10 patients with asthma who were treated with indomethacin in a double-blind, randomized, placebo-controlled, crossover fashion." | 9.08 | Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma. ( Fujimura, M; Kamio, Y; Matsuda, T; Myou, S, 1997) |
| "These results suggest an important role of cyclooxygenase pathway products in decreased response to repeated inhalation of acetaldehyde in patients with asthma." | 9.08 | Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma. ( Fujimura, M; Kamio, Y; Matsuda, T; Myou, S, 1997) |
| "We recently reported that inhaled acetaldehyde causes bronchoconstriction indirectly via histamine release in patients with asthma." | 9.07 | Inhibitory effect of a selective thromboxane synthetase inhibitor, OKY-046, on acetaldehyde-induced bronchoconstriction in asthmatic patients. ( Fujimura, M; Masuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
| "Acetaldehyde induces bronchial hyperresponsiveness in patients with asthma by mechanisms other than histamine release." | 9.07 | Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects. ( Fujimura, M; Matsuda, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
| "It has been reported that acetaldehyde may be a main factor of alcohol-induced bronchoconstriction in Japanese patients with asthma." | 9.07 | Aerosolized acetaldehyde induces histamine-mediated bronchoconstriction in asthmatics. ( Fujimura, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1993) |
| "To determine the effects of a low concentration of acetaldehyde, which itself did not trigger airway inflammation, on extant allergic airway inflammation in a murine model of allergic asthma." | 7.78 | Acetaldehyde at a low concentration synergistically exacerbates allergic airway inflammation as an endocrine-disrupting chemical and as a volatile organic compound. ( Fukahori, S; Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Nishino, T; Tsuchida, T, 2012) |
| "Exposure to acetaldehyde can enhance allergic airway inflammation in asthma." | 7.78 | Acetaldehyde at a low concentration synergistically exacerbates allergic airway inflammation as an endocrine-disrupting chemical and as a volatile organic compound. ( Fukahori, S; Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Nishino, T; Tsuchida, T, 2012) |
| "The purpose of the present study was to determine the effects of acetaldehyde on airway smooth muscle constriction and inflammation." | 7.74 | Effects of acetaldehyde on human airway constriction and inflammation. ( Fukushima, C; Kohno, S; Matsuse, H; Sadahiro, A; Shimoda, T, 2007) |
| " An oral ethanol provocation test was performed in Japanese asthmatics to measure pulmonary function, blood ethanol, acetaldehyde and histamine." | 7.74 | Effects of acetaldehyde on human airway constriction and inflammation. ( Fukushima, C; Kohno, S; Matsuse, H; Sadahiro, A; Shimoda, T, 2007) |
| "Inhaled acetaldehyde and adenosine 5'-monophosphate (AMP) cause bronchoconstriction in asthmatics by a mechanism believed to involve histamine release from airway mast cells." | 7.71 | Airway obstruction induced by inhaled acetaldehyde in asthma: repeatability relationship to adenosine 5'-monophosphate responsiveness. ( Cervera, A; Gutiérrez, V; Liñana, J; Prieto, L, 2002) |
| "A total of 78 adults (43 subjects with allergic rhinitis, 16 asthmatics and 19 healthy subjects) were challenged with increased concentrations of acetaldehyde and methacholine." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "Asthmatic subjects have an exaggerated airway response to inhaled acetaldehyde, but no information is available on airway responsiveness to this bronchoconstrictor agent in subjects with allergic rhinitis." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "The aim of this study was to determine the effect of inhaled acetaldehyde on lung function in nonasthmatic subjects with allergic rhinitis." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "The geometric mean PC(20) acetaldehyde value for asthmatics was 35." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "We conclude that subjects with allergic rhinitis are less responsive to inhaled acetaldehyde than asthmatic subjects, but more than healthy controls." | 7.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "Inhaled acetaldehyde may induce bronchoconstriction in asthmatic subjects and provides a new method to investigate airway responsiveness." | 7.70 | Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis. ( Marín, J; Millan, M; Pérez, JA; Peris, R; Prieto, L; Sánchez-Toril, F, 2000) |
| "Alcohol-induced asthma is probably caused by increased blood acetaldehyde concentration resulting from abnormalities of ALDH2 enzyme activity based on ALDH2 genotype differences." | 7.70 | Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype. ( Asai, S; Harda, S; Kohno, S; Shimoda, T; Takao, A, 1998) |
| "Our results suggest that antihistamine agents may be effective against alcohol-induced asthma by both blocking H1 receptors and inhibiting histamine release." | 7.70 | Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma. ( Asai, S; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Takao, A, 1999) |
| "We examined the inhibitory effects of azelastine hydrochloride, which inhibits histamine release and blocks H1 receptors, in alcohol-induced asthma." | 7.70 | Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma. ( Asai, S; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Takao, A, 1999) |
| "Alcohol-induced asthma, a phenomenon characteristic of Asians, is due to differences in alcohol metabolism, particularly acetaldehyde metabolism." | 7.70 | Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype. ( Asai, S; Harda, S; Kohno, S; Shimoda, T; Takao, A, 1998) |
| "Acetaldehyde is a main factor of alcohol-induced asthma." | 6.70 | Effect of a cysteinyl leukotriene antagonist, pranlukast hydrate, on acetaldehyde-induced bronchoconstriction in asthmatic patients. ( Abo, M; Fujimura, M; Hashimoto, T; Kamio, Y; Katayama, N; Kita, T; Myou, S; Nakao, S; Nishitsuji, M; Nomura, S; Yoshimi, Y, 2001) |
| "Acetaldehyde is thought to be a main factor of alcohol-induced asthma." | 6.70 | Effect of ozagrel hydrochloride, a thromboxane synthetase inhibitor, on alcoholic beverage-induced bronchoconstriction in asthmatic patients. ( Fujimura, M; Ishiura, Y; Kita, T; Kurashima, K; Myou, S; Nakao, S; Nishi, K; Tachibana, H, 2002) |
| "Acetaldehyde is an endocrine-disrupting chemical (EDC) and a volatile organic compound (VOC)." | 5.38 | Acetaldehyde at a low concentration synergistically exacerbates allergic airway inflammation as an endocrine-disrupting chemical and as a volatile organic compound. ( Fukahori, S; Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Nishino, T; Tsuchida, T, 2012) |
| "Acetaldehyde is thought to be a main factor of alcohol-induced asthma." | 5.10 | Effect of ozagrel hydrochloride, a thromboxane synthetase inhibitor, on alcoholic beverage-induced bronchoconstriction in asthmatic patients. ( Fujimura, M; Ishiura, Y; Kita, T; Kurashima, K; Myou, S; Nakao, S; Nishi, K; Tachibana, H, 2002) |
| "The two types of challenge yielded a similarly high level of sensitivity (100% for methacholine and 92% for acetaldehyde) and specificity (90 and 100%, respectively) to distinguish between asthma and controls." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The objectives of the study were to determine differences in airway responsiveness to acetaldehyde between asthmatic and healthy subjects, and to examine the relationship between acetaldehyde responsiveness and the variability of peak expiratory flow (PEF)." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "These results indicate that airway hyperresponsiveness to acetaldehyde is a sensitive and specific indicator for separating asthmatic and normal subjects." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "Bronchial responsiveness to acetaldehyde, a main factor in alcohol-induced bronchoconstriction, and methacholine were compared between 10 subjects with alcohol-induced bronchoconstriction and 16 asthmatic subjects without alcohol sensitivity." | 5.09 | Increased airway responsiveness to acetaldehyde in asthmatic subjects with alcohol-induced bronchoconstriction. ( Fujimura, M; Hashimoto, T; Ishiura, Y; Iwasa, K; Kamio, Y; Matsuda, T; Myou, S, 1999) |
| "Although airway hyperresponsiveness to inhaled acetaldehyde has been documented in Japanese patients with asthma, the response to this bronchoconstrictor agent has never been studied in Caucasians." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "The response to methacholine and acetaldehyde challenges was measured in 81 non-smoking adults (61 asthmatics and 20 normal controls)." | 5.09 | Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation. ( Belenguer, JL; Brotons, B; Casañ, R; Prieto, L; Sánchez-Toril, F; Soriano, S, 2000) |
| "Acetaldehyde is a main factor of alcohol-induced asthma." | 5.09 | Effect of a cysteinyl leukotriene antagonist, pranlukast hydrate, on acetaldehyde-induced bronchoconstriction in asthmatic patients. ( Abo, M; Fujimura, M; Hashimoto, T; Kamio, Y; Katayama, N; Kita, T; Myou, S; Nakao, S; Nishitsuji, M; Nomura, S; Yoshimi, Y, 2001) |
| "Acetaldehyde, a main factor in alcohol-induced asthma, causes bronchoconstriction indirectly through histamine release; and tachyphylaxis in response to repeated inhalation of acetaldehyde is observed in patients with asthma." | 5.08 | Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma. ( Fujimura, M; Kamio, Y; Matsuda, T; Myou, S, 1997) |
| "We investigated the bronchial response to inhaled acetaldehyde in 10 patients with asthma who were treated with indomethacin in a double-blind, randomized, placebo-controlled, crossover fashion." | 5.08 | Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma. ( Fujimura, M; Kamio, Y; Matsuda, T; Myou, S, 1997) |
| "These results suggest an important role of cyclooxygenase pathway products in decreased response to repeated inhalation of acetaldehyde in patients with asthma." | 5.08 | Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma. ( Fujimura, M; Kamio, Y; Matsuda, T; Myou, S, 1997) |
| "We previously reported that inhaled acetaldehyde, a metabolite of ethanol and a main factor in alcohol-induced asthma, causes bronchoconstriction indirectly through endogenously released histamine in asthmatic subjects." | 5.08 | Repeated inhalation challenge with exogenous and endogenous histamine released by acetaldehyde inhalation in asthmatic patients. ( Bando, T; Fujimura, M; Kamio, Y; Matsuda, T; Myou, S; Nakatsumi, Y, 1995) |
| "It has been reported that acetaldehyde may be a main factor of alcohol-induced bronchoconstriction in Japanese patients with asthma." | 5.07 | Aerosolized acetaldehyde induces histamine-mediated bronchoconstriction in asthmatics. ( Fujimura, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1993) |
| "We recently reported that inhaled acetaldehyde causes bronchoconstriction indirectly via histamine release in patients with asthma." | 5.07 | Inhibitory effect of a selective thromboxane synthetase inhibitor, OKY-046, on acetaldehyde-induced bronchoconstriction in asthmatic patients. ( Fujimura, M; Masuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
| "Acetaldehyde induces bronchial hyperresponsiveness in patients with asthma by mechanisms other than histamine release." | 5.07 | Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects. ( Fujimura, M; Matsuda, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
| "Exposure to acetaldehyde can enhance allergic airway inflammation in asthma." | 3.78 | Acetaldehyde at a low concentration synergistically exacerbates allergic airway inflammation as an endocrine-disrupting chemical and as a volatile organic compound. ( Fukahori, S; Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Nishino, T; Tsuchida, T, 2012) |
| "To determine the effects of a low concentration of acetaldehyde, which itself did not trigger airway inflammation, on extant allergic airway inflammation in a murine model of allergic asthma." | 3.78 | Acetaldehyde at a low concentration synergistically exacerbates allergic airway inflammation as an endocrine-disrupting chemical and as a volatile organic compound. ( Fukahori, S; Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Nishino, T; Tsuchida, T, 2012) |
| " An oral ethanol provocation test was performed in Japanese asthmatics to measure pulmonary function, blood ethanol, acetaldehyde and histamine." | 3.74 | Effects of acetaldehyde on human airway constriction and inflammation. ( Fukushima, C; Kohno, S; Matsuse, H; Sadahiro, A; Shimoda, T, 2007) |
| "The purpose of the present study was to determine the effects of acetaldehyde on airway smooth muscle constriction and inflammation." | 3.74 | Effects of acetaldehyde on human airway constriction and inflammation. ( Fukushima, C; Kohno, S; Matsuse, H; Sadahiro, A; Shimoda, T, 2007) |
| "Inhaled acetaldehyde and adenosine 5'-monophosphate (AMP) cause bronchoconstriction in asthmatics by a mechanism believed to involve histamine release from airway mast cells." | 3.71 | Airway obstruction induced by inhaled acetaldehyde in asthma: repeatability relationship to adenosine 5'-monophosphate responsiveness. ( Cervera, A; Gutiérrez, V; Liñana, J; Prieto, L, 2002) |
| "Asthmatic subjects have an exaggerated airway response to inhaled acetaldehyde, but no information is available on airway responsiveness to this bronchoconstrictor agent in subjects with allergic rhinitis." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "The aim of this study was to determine the effect of inhaled acetaldehyde on lung function in nonasthmatic subjects with allergic rhinitis." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "A total of 78 adults (43 subjects with allergic rhinitis, 16 asthmatics and 19 healthy subjects) were challenged with increased concentrations of acetaldehyde and methacholine." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "The geometric mean PC(20) acetaldehyde value for asthmatics was 35." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "We conclude that subjects with allergic rhinitis are less responsive to inhaled acetaldehyde than asthmatic subjects, but more than healthy controls." | 3.71 | Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness. ( Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F, 2002) |
| "Inhaled acetaldehyde may induce bronchoconstriction in asthmatic subjects and provides a new method to investigate airway responsiveness." | 3.70 | Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis. ( Marín, J; Millan, M; Pérez, JA; Peris, R; Prieto, L; Sánchez-Toril, F, 2000) |
| "We examined the inhibitory effects of azelastine hydrochloride, which inhibits histamine release and blocks H1 receptors, in alcohol-induced asthma." | 3.70 | Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma. ( Asai, S; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Takao, A, 1999) |
| "Alcohol-induced asthma is probably caused by increased blood acetaldehyde concentration resulting from abnormalities of ALDH2 enzyme activity based on ALDH2 genotype differences." | 3.70 | Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype. ( Asai, S; Harda, S; Kohno, S; Shimoda, T; Takao, A, 1998) |
| "Alcohol-induced asthma, a phenomenon characteristic of Asians, is due to differences in alcohol metabolism, particularly acetaldehyde metabolism." | 3.70 | Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype. ( Asai, S; Harda, S; Kohno, S; Shimoda, T; Takao, A, 1998) |
| "Our results suggest that antihistamine agents may be effective against alcohol-induced asthma by both blocking H1 receptors and inhibiting histamine release." | 3.70 | Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma. ( Asai, S; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Takao, A, 1999) |
| "An oral ethanol challenge test, a leukocyte histamine release test, and an ELISA for detection of IgE specific to acetaldehyde-human serum albumin conjugate were carried out in 42 adults with bronchial asthma and nine healthy adults." | 3.69 | Investigation of the mechanism of alcohol-induced bronchial asthma. ( Asai, S; Fujiwara, C; Hara, K; Kohno, S; Matsuse, H; Sakai, H; Shimoda, T; Takao, A; Watanabe, T, 1996) |
| "Acetaldehyde is a main factor of alcohol-induced asthma." | 2.70 | Effect of a cysteinyl leukotriene antagonist, pranlukast hydrate, on acetaldehyde-induced bronchoconstriction in asthmatic patients. ( Abo, M; Fujimura, M; Hashimoto, T; Kamio, Y; Katayama, N; Kita, T; Myou, S; Nakao, S; Nishitsuji, M; Nomura, S; Yoshimi, Y, 2001) |
| "Acetaldehyde is thought to be a main factor of alcohol-induced asthma." | 2.70 | Effect of ozagrel hydrochloride, a thromboxane synthetase inhibitor, on alcoholic beverage-induced bronchoconstriction in asthmatic patients. ( Fujimura, M; Ishiura, Y; Kita, T; Kurashima, K; Myou, S; Nakao, S; Nishi, K; Tachibana, H, 2002) |
| "Acetaldehyde is an endocrine-disrupting chemical (EDC) and a volatile organic compound (VOC)." | 1.38 | Acetaldehyde at a low concentration synergistically exacerbates allergic airway inflammation as an endocrine-disrupting chemical and as a volatile organic compound. ( Fukahori, S; Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Nishino, T; Tsuchida, T, 2012) |
| "We report the case of a severe bronchial asthma attack 15 minutes after the ingestion of food containing small amounts of alcohol." | 1.31 | Acute severe alcohol-induced bronchial asthma. ( Okazawa, M; Saito, Y; Sakakibara, H; Sasaki, F; Sato, M; Suetsugu, S; Tanaka, I, 2001) |
| "Alcohol-induced bronchial asthma seems to develop as follows." | 1.29 | Investigation of the mechanism of alcohol-induced bronchial asthma. ( Asai, S; Fujiwara, C; Hara, K; Kohno, S; Matsuse, H; Sakai, H; Shimoda, T; Takao, A; Watanabe, T, 1996) |
| "The histamine release was significantly higher in the asthma group (both responders and nonresponders) than in the healthy control group." | 1.29 | Investigation of the mechanism of alcohol-induced bronchial asthma. ( Asai, S; Fujiwara, C; Hara, K; Kohno, S; Matsuse, H; Sakai, H; Shimoda, T; Takao, A; Watanabe, T, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (43.48) | 18.2507 |
| 2000's | 10 (43.48) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, X | 1 |
| Ma, H | 1 |
| Pan, Q | 1 |
| Wang, H | 1 |
| Qian, X | 1 |
| Song, P | 1 |
| Zou, L | 1 |
| Mao, M | 1 |
| Xia, S | 1 |
| Ge, G | 1 |
| Yang, L | 1 |
| Chang, PT | 1 |
| Hung, PC | 1 |
| Tsai, SW | 1 |
| Kawano, T | 1 |
| Matsuse, H | 4 |
| Fukahori, S | 1 |
| Tsuchida, T | 1 |
| Nishino, T | 1 |
| Fukushima, C | 2 |
| Kohno, S | 5 |
| Prieto, L | 4 |
| Gutiérrez, V | 2 |
| Cervera, A | 1 |
| Liñana, J | 1 |
| Shimoda, T | 4 |
| Sadahiro, A | 1 |
| Asai, S | 4 |
| Myou, S | 9 |
| Fujimura, M | 9 |
| Kamio, Y | 4 |
| Bando, T | 1 |
| Nakatsumi, Y | 1 |
| Matsuda, T | 5 |
| Nishi, K | 4 |
| Ohka, T | 3 |
| Takada, A | 1 |
| Tsutsumi, M | 1 |
| Kobayashi, Y | 1 |
| Masuda, T | 1 |
| Matsuda, M | 1 |
| Takao, A | 3 |
| Fujiwara, C | 1 |
| Sakai, H | 1 |
| Watanabe, T | 1 |
| Hara, K | 1 |
| Harda, S | 1 |
| Mitsuta, K | 1 |
| Obase, Y | 1 |
| Ishiura, Y | 2 |
| Iwasa, K | 1 |
| Hashimoto, T | 2 |
| Sánchez-Toril, F | 3 |
| Brotons, B | 1 |
| Soriano, S | 1 |
| Casañ, R | 1 |
| Belenguer, JL | 1 |
| Peris, R | 1 |
| Pérez, JA | 1 |
| Millan, M | 1 |
| Marín, J | 1 |
| Kita, T | 2 |
| Katayama, N | 1 |
| Abo, M | 1 |
| Yoshimi, Y | 1 |
| Nishitsuji, M | 1 |
| Nomura, S | 1 |
| Nakao, S | 2 |
| Saito, Y | 1 |
| Sasaki, F | 1 |
| Tanaka, I | 1 |
| Sato, M | 1 |
| Okazawa, M | 1 |
| Sakakibara, H | 1 |
| Suetsugu, S | 1 |
| Marín, MJ | 1 |
| Kurashima, K | 1 |
| Tachibana, H | 1 |
2 reviews available for acetaldehyde and Asthma, Bronchial
| Article | Year |
|---|---|
[Alcohol-induced asthma].
Topics: Acetaldehyde; Adult; Alcohol Drinking; Aldehyde Dehydrogenase; Asthma; Ethanol; Histamine Release; H | 2008 |
Genotypes of ALDH2 related to liver and pulmonary diseases and other genetic factors related to alcoholic liver disease.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Asthma; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Syste | 1994 |
10 trials available for acetaldehyde and Asthma, Bronchial
| Article | Year |
|---|---|
Theophylline Acetaldehyde as the Initial Product in Doxophylline Metabolism in Human Liver.
Topics: Acetaldehyde; Adult; Animals; Asthma; Bronchodilator Agents; Cytochrome P-450 Enzyme System; Female; | 2020 |
Repeated inhalation challenge with exogenous and endogenous histamine released by acetaldehyde inhalation in asthmatic patients.
Topics: Acetaldehyde; Administration, Inhalation; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial | 1995 |
Aerosolized acetaldehyde induces histamine-mediated bronchoconstriction in asthmatics.
Topics: Acetaldehyde; Adult; Aerosols; Analysis of Variance; Asthma; Bronchial Provocation Tests; Bronchocon | 1993 |
Inhibitory effect of a selective thromboxane synthetase inhibitor, OKY-046, on acetaldehyde-induced bronchoconstriction in asthmatic patients.
Topics: Acetaldehyde; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Cross-Over Studies; D | 1994 |
Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects.
Topics: Acetaldehyde; Adult; Aged; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; | 1994 |
Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma.
Topics: Acetaldehyde; Administration, Inhalation; Administration, Oral; Adult; Aged; Asthma; Bronchoconstric | 1997 |
Increased airway responsiveness to acetaldehyde in asthmatic subjects with alcohol-induced bronchoconstriction.
Topics: Acetaldehyde; Administration, Inhalation; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial | 1999 |
Airway responsiveness to acetaldehyde in patients with asthma: relationship to methacholine responsiveness and peak expiratory flow variation.
Topics: Acetaldehyde; Adult; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tes | 2000 |
Effect of a cysteinyl leukotriene antagonist, pranlukast hydrate, on acetaldehyde-induced bronchoconstriction in asthmatic patients.
Topics: Acetaldehyde; Adult; Asthma; Bronchoconstriction; Chromones; Cross-Over Studies; Cysteine; Double-Bl | 2001 |
Effect of ozagrel hydrochloride, a thromboxane synthetase inhibitor, on alcoholic beverage-induced bronchoconstriction in asthmatic patients.
Topics: Acetaldehyde; Adult; Alcoholic Beverages; Asthma; Beer; Bronchial Provocation Tests; Bronchoconstric | 2002 |
11 other studies available for acetaldehyde and Asthma, Bronchial
| Article | Year |
|---|---|
Occupational exposures of flour dust and airborne chemicals at bakeries in Taiwan.
Topics: Acetaldehyde; Air Pollutants, Occupational; Asthma; Dust; Flavoring Agents; Flour; Food Handling; Hu | 2018 |
Acetaldehyde at a low concentration synergistically exacerbates allergic airway inflammation as an endocrine-disrupting chemical and as a volatile organic compound.
Topics: Acetaldehyde; Administration, Intranasal; Animals; Asthma; Bronchoconstriction; Disease Models, Anim | 2012 |
Airway obstruction induced by inhaled acetaldehyde in asthma: repeatability relationship to adenosine 5'-monophosphate responsiveness.
Topics: Acetaldehyde; Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adult; Airway Obstruc | 2002 |
Effects of acetaldehyde on human airway constriction and inflammation.
Topics: Acetaldehyde; Administration, Oral; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; A | 2007 |
Investigation of the mechanism of alcohol-induced bronchial asthma.
Topics: Acetaldehyde; Adult; Aged; Albumins; Alcohol Drinking; Asthma; Enzyme-Linked Immunosorbent Assay; Fe | 1996 |
Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype.
Topics: Acetaldehyde; Adult; Aged; Aldehyde Oxidoreductases; Allergens; Asthma; Ethanol; Female; Genotype; H | 1998 |
Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma.
Topics: Acetaldehyde; Adult; Aged; Asthma; Bronchoconstrictor Agents; Bronchodilator Agents; Ethanol; Female | 1999 |
Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis.
Topics: Acetaldehyde; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bro | 2000 |
Alcohol-induced asthma.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Asthma; Ethanol; Genotype; Humans; Racial Groups | 2001 |
Acute severe alcohol-induced bronchial asthma.
Topics: Acetaldehyde; Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Asthma; Ethanol; | 2001 |
Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness.
Topics: Acetaldehyde; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstric | 2002 |