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acetaldehyde and Anxiety

acetaldehyde has been researched along with Anxiety in 7 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
" We investigated whether variation in genes encoding cytochrome P450 2E1 (CYP2E1) or acetaldehyde-metabolising enzymes (ALDH1A1, ALDH2) might alter the risk of AD, with and without symptoms of anxiety, in a Cape population with mixed ancestry."7.80Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population. ( Crawford, A; Dalvie, S; Fein, G; King, A; Koenen, K; Lewis, S; Liberzon, I; Ramesar, R; Stein, DJ, 2014)
" We investigated whether variation in genes encoding cytochrome P450 2E1 (CYP2E1) or acetaldehyde-metabolising enzymes (ALDH1A1, ALDH2) might alter the risk of AD, with and without symptoms of anxiety, in a Cape population with mixed ancestry."3.80Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population. ( Crawford, A; Dalvie, S; Fein, G; King, A; Koenen, K; Lewis, S; Liberzon, I; Ramesar, R; Stein, DJ, 2014)
"We investigated the effect of direct administration of acetaldehyde on behavioral measures of anxiety and on hormonal markers of stress in mice."3.78Anxiogenic and stress-inducing effects of peripherally administered acetaldehyde in mice: similarities with the disulfiram-ethanol reaction. ( Aragon, CM; Correa, M; Escrig, MA; Pardo, M, 2012)
"Peripheral accumulation of acetaldehyde, the first metabolite of ethanol, produces autonomic responses in humans called "flushing"."3.78Anxiogenic and stress-inducing effects of peripherally administered acetaldehyde in mice: similarities with the disulfiram-ethanol reaction. ( Aragon, CM; Correa, M; Escrig, MA; Pardo, M, 2012)
"A hereditary element to alcohol dependence has been suggested by several adoption and twin studies, but the many contradictions between research results emphasise that any genetic contribution is overshadowed by socio-cultural factors."2.37Psychiatric advances in the understanding and treatment of alcohol dependence. ( Madden, JS, 1984)
"Acetaldehyde was ten times more potent than ethanol at inducing corticosterone release."1.38Anxiogenic and stress-inducing effects of peripherally administered acetaldehyde in mice: similarities with the disulfiram-ethanol reaction. ( Aragon, CM; Correa, M; Escrig, MA; Pardo, M, 2012)
" Rats injected with ICV ethanol or acetaldehyde showed an inverted U-shaped dose-response curve, with moderate doses increasing motor activity."1.32Open field locomotor effects in rats after intraventricular injections of ethanol and the ethanol metabolites acetaldehyde and acetate. ( Arizzi, MN; Betz, A; Correa, M; Mingote, S; Salamone, JD, 2003)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crawford, A1
Dalvie, S1
Lewis, S1
King, A1
Liberzon, I1
Fein, G1
Koenen, K1
Ramesar, R1
Stein, DJ1
Correa, M3
Manrique, HM1
Font, L1
Escrig, MA2
Aragon, CM2
Pardo, M1
Arizzi, MN1
Betz, A1
Mingote, S1
Salamone, JD1
Madden, JS1
Tanaka, T1
Mukasa, H1
Yamada, S1
Hashimoto, M1
Inanaga, K1
Nathan, PE1
Zare, NC1
Ferneau, EW1
Lowenstein, LM1

Reviews

1 review available for acetaldehyde and Anxiety

ArticleYear
Psychiatric advances in the understanding and treatment of alcohol dependence.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1984, Volume: 19, Issue:4

    Topics: Acetaldehyde; Adoption; Alcohol Oxidoreductases; Alcoholic Intoxication; Alcoholism; Antidepressive

1984

Other Studies

6 other studies available for acetaldehyde and Anxiety

ArticleYear
Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population.
    Metabolic brain disease, 2014, Volume: 29, Issue:2

    Topics: Acetaldehyde; Adolescent; Alcoholism; Anxiety; Case-Control Studies; Cohort Studies; Comorbidity; Fe

2014
Reduction in the anxiolytic effects of ethanol by centrally formed acetaldehyde: the role of catalase inhibitors and acetaldehyde-sequestering agents.
    Psychopharmacology, 2008, Volume: 200, Issue:4

    Topics: Acetaldehyde; Amitrole; Animals; Anti-Anxiety Agents; Anxiety; Catalase; Central Nervous System Depr

2008
Anxiogenic and stress-inducing effects of peripherally administered acetaldehyde in mice: similarities with the disulfiram-ethanol reaction.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 100, Issue:3

    Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Anxiety; Behavi

2012
Open field locomotor effects in rats after intraventricular injections of ethanol and the ethanol metabolites acetaldehyde and acetate.
    Brain research bulletin, 2003, Dec-30, Volume: 62, Issue:3

    Topics: Acetaldehyde; Acetates; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Etha

2003
Individual differences in psychophysiological responses after alcohol ingestion.
    The Japanese journal of psychiatry and neurology, 1987, Volume: 41, Issue:1

    Topics: Acetaldehyde; Adult; Alcohol Drinking; Anxiety; Arousal; Blinking; Ethanol; Heart Rate; Humans; Indi

1987
Effects of congener differences in alcoholic beverages on the behavior of alcoholics.
    Quarterly journal of studies on alcohol, 1970, Volume: 5

    Topics: Acetaldehyde; Acetates; Adult; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Alcohols; Anxiety;

1970