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acetaldehyde and Aneuploid

acetaldehyde has been researched along with Aneuploid in 10 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Research Excerpts

ExcerptRelevanceReference
"AA induced an increase of aneuploidy and chromosome breaks and exchanges."5.27Acetaldehyde-induced aneuploidy in cultured Chinese hamster cells. ( Dulout, FN; Furnus, CC, 1988)
" Other striking features presented in this review are their aneuploidy, and their mitochondrial DNA polymorphism which seems to reflect adaptive evolution of the yeast to a stressful environment where acetaldehyde and ethanol are present at elevated concentration."4.89Flor yeasts of Saccharomyces cerevisiae--their ecology, genetics and metabolism. ( Alexandre, H, 2013)
" Four suspected aneuploidy-inducing chemicals, acetaldehyde (AA), diethylstilbestrol (DES), diethylstilbestrol dipropionate (DESdp) and griseofulvin (GF), have been evaluated with the assay."3.69Detection of the centromere in micronuclei by fluorescence in situ hybridization: its application to the human lymphocyte micronucleus assay after treatment with four suspected aneugens. ( Cocchi, L; Migliore, L; Scarpato, R, 1996)
"We tested six additional chemicals (acetaldehyde, benomyl, diethylstilboestrol, diethylstilboestrol dipropionate, griseofulvin, and mercaptoethanol) for in vitro systems of the coordinated programme to study aneuploidy induction sponsored by the Commission of the European Communities in two in vitro test systems."3.68Analysis of the six additional chemicals for in vitro assays of the European Economic Communities' EEC aneuploidy programme using Saccharomyces cerevisiae D61.M and the in vitro porcine brain tubulin assembly assay. ( Albertini, S; Brunner, M; Würgler, FE, 1993)
"Acetaldehyde induced an increase in chromosomal malsegregation with the cold treatment protocol (LEDT: 1."1.29Analysis of the six additional chemicals for in vitro assays of the European Economic Communities' EEC aneuploidy programme using Saccharomyces cerevisiae D61.M and the in vitro porcine brain tubulin assembly assay. ( Albertini, S; Brunner, M; Würgler, FE, 1993)
"Four suspected aneuploidy-inducing chemicals, acetaldehyde (AA), diethylstilbestrol (DES), diethylstilbestrol dipropionate (DESdp) and griseofulvin (GF), have been evaluated with the assay."1.29Detection of the centromere in micronuclei by fluorescence in situ hybridization: its application to the human lymphocyte micronucleus assay after treatment with four suspected aneugens. ( Cocchi, L; Migliore, L; Scarpato, R, 1996)
" The same bell-shaped dose-response curve was shown by the spindle poison chloral hydrate, which was active in the range 6-10 mM."1.28A comparative study on ethanol and acetaldehyde as inducers of chromosome malsegregation in Aspergillus nidulans. ( Carere, A; Conti, G; Conti, L; Crebelli, R, 1989)
"AA induced an increase of aneuploidy and chromosome breaks and exchanges."1.27Acetaldehyde-induced aneuploidy in cultured Chinese hamster cells. ( Dulout, FN; Furnus, CC, 1988)
"Similar rates of aneuploidy have also been observed when recently ovulated eggs are briefly exposed in vitro to a dilute solution of ethanol in tissue culture medium."1.27An hypothesis regarding the origin of aneuploidy in man: indirect evidence from an experimental model. ( Kaufman, MH, 1985)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's3 (30.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alexandre, H1
Kayani, MA1
Parry, JM1
Albertini, S1
Brunner, M1
Würgler, FE1
Migliore, L1
Cocchi, L1
Scarpato, R1
Il'inskikh, NN1
Il'inskikh, IN1
Makarov, LN1
Chernoskutova, SA1
Crebelli, R2
Conti, G2
Conti, L2
Carere, A2
Natarajan, AT1
Dulout, FN1
Furnus, CC1
Kaufman, MH1

Reviews

1 review available for acetaldehyde and Aneuploid

ArticleYear
Flor yeasts of Saccharomyces cerevisiae--their ecology, genetics and metabolism.
    International journal of food microbiology, 2013, Oct-15, Volume: 167, Issue:2

    Topics: Acetaldehyde; Aneuploidy; DNA, Mitochondrial; Ethanol; Fermentation; Membrane Glycoproteins; Phenoty

2013

Other Studies

9 other studies available for acetaldehyde and Aneuploid

ArticleYear
The in vitro genotoxicity of ethanol and acetaldehyde.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:1

    Topics: Acetaldehyde; Aneuploidy; Apoptosis; Cell Line; Cell Proliferation; Cell Survival; Central Nervous S

2010
Analysis of the six additional chemicals for in vitro assays of the European Economic Communities' EEC aneuploidy programme using Saccharomyces cerevisiae D61.M and the in vitro porcine brain tubulin assembly assay.
    Environmental and molecular mutagenesis, 1993, Volume: 21, Issue:2

    Topics: Acetaldehyde; Aneuploidy; Animals; Benomyl; Diethylstilbestrol; Dose-Response Relationship, Drug; Eu

1993
Detection of the centromere in micronuclei by fluorescence in situ hybridization: its application to the human lymphocyte micronucleus assay after treatment with four suspected aneugens.
    Mutagenesis, 1996, Volume: 11, Issue:3

    Topics: Acetaldehyde; Aneuploidy; Centromere; Diethylstilbestrol; Drug Evaluation, Preclinical; Griseofulvin

1996
[Effect of ethanol and its metabolite acetaldehyde on the chromosomal apparatus of rat and human cells].
    Tsitologiia, 1978, Volume: 20, Issue:4

    Topics: Acetaldehyde; Adult; Alcoholism; Aneuploidy; Animals; Chromosome Aberrations; Ethanol; Humans; Leuko

1978
Chloroacetaldehyde is a powerful inducer of mitotic aneuploidy in Aspergillus nidulans.
    Mutagenesis, 1990, Volume: 5, Issue:2

    Topics: Acetaldehyde; Aneuploidy; Animals; Aspergillus nidulans; Cattle; Chromosomes, Fungal; Crossing Over,

1990
Development of techniques to study induction of aneuploidy in somatic cells in vitro and in vivo.
    Progress in clinical and biological research, 1989, Volume: 318

    Topics: Acetaldehyde; Aneuploidy; Animals; Chromosome Aberrations; Cricetinae; Cricetulus; Demecolcine; Diet

1989
A comparative study on ethanol and acetaldehyde as inducers of chromosome malsegregation in Aspergillus nidulans.
    Mutation research, 1989, Volume: 215, Issue:2

    Topics: Acetaldehyde; Alcohols; Aneuploidy; Aspergillus nidulans; Dose-Response Relationship, Drug; Ethanol;

1989
Acetaldehyde-induced aneuploidy in cultured Chinese hamster cells.
    Mutagenesis, 1988, Volume: 3, Issue:3

    Topics: Acetaldehyde; Aneuploidy; Animals; Cell Line; Cell Nucleus; Diethylstilbestrol; Ethanol; Karyotyping

1988
An hypothesis regarding the origin of aneuploidy in man: indirect evidence from an experimental model.
    Journal of medical genetics, 1985, Volume: 22, Issue:3

    Topics: Acetaldehyde; Age Factors; Anesthetics; Aneuploidy; Animals; Ethanol; Female; Humans; Male; Meiosis;

1985