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acetaldehyde and Alcoholic Pancreatitis

acetaldehyde has been researched along with Alcoholic Pancreatitis in 11 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Research Excerpts

ExcerptRelevanceReference
"During development of alcoholic pancreatitis, oxidative (acetaldehyde) and nonoxidative metabolites (ethyl palmitate, ethyl oleate), rather than ethanol itself, mediate toxic injury."3.78Effects of ethanol metabolites on exocytosis of pancreatic acinar cells in rats. ( Chidambaram, S; Dolai, S; Fernandez, NA; Gaisano, HY; Lam, PPL; Liang, T, 2012)
"During development of alcoholic pancreatitis, oxidative (acetaldehyde) and nonoxidative metabolites (ethyl palmitate, ethyl oleate), rather than ethanol itself, mediate toxic injury."1.38Effects of ethanol metabolites on exocytosis of pancreatic acinar cells in rats. ( Chidambaram, S; Dolai, S; Fernandez, NA; Gaisano, HY; Lam, PPL; Liang, T, 2012)
"However, mechanism of alcoholic pancreatitis remains obscure due to lack of a suitable animal model."1.36Pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice after subchronic exposure to ethanol. ( Ansari, GA; Bhopale, KK; Boor, PJ; Kaphalia, BS; Kondraganti, S; Wu, H, 2010)
"An acetaldehyde (AcH) adduct was prepared using rabbit low-density lipoprotein as carrier proteins."1.30An enzyme immune assay for serum anti-acetaldehyde adduct antibody using low-density lipoprotein adduct and its significance in alcoholic liver injury. ( Matsuzaki, S; Nagata, N; Nishizaki, Y; Tsuda, M; Watanabe, N, 1998)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's4 (36.36)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Takahashi, T1
Miao, Y1
Kang, F1
Dolai, S2
Gaisano, HY2
Zakhari, S1
Lawrencia, C1
Charrier, A1
Huang, G1
Brigstock, DR1
Kaphalia, BS1
Bhopale, KK1
Kondraganti, S1
Wu, H1
Boor, PJ1
Ansari, GA1
Jelski, W1
Kutyłowska, E1
Szmitkowski, M1
Liang, T1
Lam, PPL1
Fernandez, NA1
Chidambaram, S1
Lerch, MM1
Albrecht, E1
Ruthenbürger, M1
Mayerle, J1
Halangk, W1
Krüger, B1
Apte, MV1
Pirola, RC1
Wilson, JS2
Korsten, MA1
Haber, PS1
Nagata, N1
Nishizaki, Y1
Watanabe, N1
Tsuda, M1
Matsuzaki, S1
Brecher, AS1
Yang, MP1

Reviews

5 reviews available for acetaldehyde and Alcoholic Pancreatitis

ArticleYear
Susceptibility Factors and Cellular Mechanisms Underlying Alcoholic Pancreatitis.
    Alcoholism, clinical and experimental research, 2020, Volume: 44, Issue:4

    Topics: Acetaldehyde; Autophagy; Calcium; Disease Susceptibility; Endoplasmic Reticulum Stress; Ethanol; Exo

2020
Chronic alcohol drinking: Liver and pancreatic cancer?
    Clinics and research in hepatology and gastroenterology, 2015, Volume: 39 Suppl 1

    Topics: Acetaldehyde; Adaptive Immunity; Alcoholism; Carcinoma, Hepatocellular; Central Nervous System Depre

2015
[The role of ethanol in pathogenesis of pancreatitis].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2011, Volume: 30, Issue:175

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Ethanol; Humans; Oxidation-Reduction; Oxidative Stress

2011
Battle-scarred pancreas: role of alcohol and pancreatic stellate cells in pancreatic fibrosis.
    Journal of gastroenterology and hepatology, 2006, Volume: 21 Suppl 3

    Topics: Acetaldehyde; Animals; Enzyme Activation; Enzyme Inhibitors; Ethanol; Humans; MAP Kinase Signaling S

2006
An overview of extrapancreatic factors in the pathogenesis of alcoholic pancreatitis.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1994, Volume: 2

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Diet; Ethanol; Free Radicals; Gastrointestinal Hormone

1994

Other Studies

6 other studies available for acetaldehyde and Alcoholic Pancreatitis

ArticleYear
Ethanol-mediated expression of connective tissue growth factor (CCN2) in mouse pancreatic stellate cells.
    Growth factors (Chur, Switzerland), 2009, Volume: 27, Issue:2

    Topics: Acetaldehyde; Animals; Base Sequence; Cells, Cultured; Connective Tissue Growth Factor; DNA Primers;

2009
Pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice after subchronic exposure to ethanol.
    Toxicology and applied pharmacology, 2010, Aug-01, Volume: 246, Issue:3

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Cathepsin B; Disease Models, Animal; Endoplasmic Retic

2010
Effects of ethanol metabolites on exocytosis of pancreatic acinar cells in rats.
    Gastroenterology, 2012, Volume: 143, Issue:3

    Topics: Acetaldehyde; Actin Cytoskeleton; Amylases; Animals; Calcium Signaling; Dose-Response Relationship,

2012
Pathophysiology of alcohol-induced pancreatitis.
    Pancreas, 2003, Volume: 27, Issue:4

    Topics: Acetaldehyde; Cathepsin B; Enzyme Activation; Humans; Pancreas; Pancreatitis, Alcoholic; Trypsin

2003
An enzyme immune assay for serum anti-acetaldehyde adduct antibody using low-density lipoprotein adduct and its significance in alcoholic liver injury.
    Alcoholism, clinical and experimental research, 1998, Volume: 22, Issue:S3 Pt 1

    Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Animals; Antibodies; Cattle; Female; Humans; Immunoenz

1998
Acetaldehyde inhibits chymotrypsin and serum anti-chymotrypsin activity.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 1998, Volume: 46, Issue:4

    Topics: Acetaldehyde; Chymotrypsin; Humans; Pancreatitis, Alcoholic; Protease Inhibitors

1998