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acetaldehyde and Alcohol Related Neurodevelopmental Disorder

acetaldehyde has been researched along with Alcohol Related Neurodevelopmental Disorder in 43 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Research Excerpts

ExcerptRelevanceReference
"Separately, using the key words fetal alcohol syndrome, epidemiology, prevalence, incidence, and frequency, articles were identified reporting ARBD incidences among the offspring of heavy drinkers."5.31The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure. ( Einarson, TR; Hard, ML; Koren, G, 2001)
"To compare the usefulness of carbohydrate-deficient transferrin (CDT), the ratio of CDT to total transferrin, and hemoglobin-acetaldehyde adducts with mean cell volume (MCV) and gamma-glutamyl transferase (GGT) in the follow-up of alcohol abuse during pregnancy."3.70Mean cell volume and gamma-glutamyl transferase are superior to carbohydrate-deficient transferrin and hemoglobin-acetaldehyde adducts in the follow-up of pregnant women with alcohol abuse. ( Eriksson, CJ; Halmesmäki, E; Niemelä, O; Sarkola, T; Sillanaukee, P, 2000)
"Acute alcohol abuse causes damage to and functional impairment of several organs affecting protein, carbohydrate, and fat metabolism."2.46Cellular and mitochondrial effects of alcohol consumption. ( Manzo-Avalos, S; Saavedra-Molina, A, 2010)
"Alcohol dependence is correlated with a wide spectrum of medical, psychological, behavioral, and social problems."2.46Cellular and mitochondrial effects of alcohol consumption. ( Manzo-Avalos, S; Saavedra-Molina, A, 2010)
"The biochemical basis of fetal alcohol syndrome is low hepatic alcohol dehydrogenase (EC 1."2.36Effect of alcohol on the heart and cardiac metabolism. ( Bing, RJ, 1982)
"Separately, using the key words fetal alcohol syndrome, epidemiology, prevalence, incidence, and frequency, articles were identified reporting ARBD incidences among the offspring of heavy drinkers."1.31The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure. ( Einarson, TR; Hard, ML; Koren, G, 2001)
"The adverse effects of maternal alcohol consumption on the development of the fetus are well known."1.29Protective effect of Liv.52 on alcohol-induced fetotoxicity. ( Chauhan, BL; Gopumadhavan, S; Jagadeesh, S; Kulkarni, RD, 1993)
"The proximate teratogen of the fetal alcohol syndrome is unknown."1.27Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde. ( Blakley, PM; Scott, WJ, 1984)
"Acetaldehyde was detectable in maternal blood following all treatments and in maternal liver and embryos following treatment with 7 g/kg ethanol."1.27Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 2. Pharmacokinetics of the placental transfer of ethanol and acetaldehyde. ( Blakley, PM; Scott, WJ, 1984)
"Acetaldehyde-treated females had more resorptions both at mid-gestation and at term, though no significant difference in maternal weight gain was observed."1.26The teratogenic effect of acetaldehyde: implications for the study of the fetal alcohol syndrome. ( Kaufman, MH; O'Shea, KS, 1979)
"The symptoms of the fetal alcohol syndrome and their frequency of appearance are described based on 41 reports in the literature and on own observations."1.26The fetal alcohol syndrome: symptoms and pathogenesis. ( Igali, S; Imrei, J; Kardos, G; Leisztner, L; Osztovics, M; Szaszovszky, E; Véghelyi, PV, 1978)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199027 (62.79)18.7374
1990's8 (18.60)18.2507
2000's4 (9.30)29.6817
2010's4 (9.30)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manzo-Avalos, S1
Saavedra-Molina, A1
Joenje, H1
Langevin, F1
Crossan, GP1
Rosado, IV1
Arends, MJ1
Patel, KJ1
Joya, X1
Friguls, B1
Ortigosa, S1
Papaseit, E1
Martínez, SE1
Manich, A1
Garcia-Algar, O1
Pacifici, R1
Vall, O1
Pichini, S1
Cook, JD1
Lee, RD1
An, SM1
Kim, SS1
Rhee, GS1
Kwack, SJ1
Seok, JH1
Chae, SY1
Park, CH1
Choi, YW1
Kim, HS1
Cho, HY1
Lee, BM1
Park, KL1
Véghelyi, PV5
Ryle, PR1
Thomson, AD1
Bing, RJ1
Blakley, PM2
Scott, WJ2
Sreenathan, RN2
Singh, S2
Padmanabhan, R2
Campbell, MA1
Fantel, AG1
Webster, WS1
Walsh, DA1
McEwen, SE1
Lipson, AH1
Mukherjee, AB1
Hodgen, GD1
Skakun, NP1
Majewski, F1
Leistner, L1
Popov, VB1
Vaisman, BL1
Puchkov, VF1
Ignat'eva, TV1
Véghelyi, P1
Leisztner, L2
Osztovics, M4
Korányi, G1
Kardos, G2
Ullrich, E1
Cooper, P1
Gopumadhavan, S1
Jagadeesh, S1
Chauhan, BL1
Kulkarni, RD1
Hamby-Mason, R1
Chen, JJ1
Schenker, S2
Perez, A1
Henderson, GI2
Stoler, JM1
Huntington, KS1
Peterson, CM1
Peterson, KP1
Daniel, P1
Aboagye, KK1
Lieberman, E1
Ryan, L1
Holmes, LB1
Sarkola, T1
Eriksson, CJ1
Niemelä, O2
Sillanaukee, P1
Halmesmäki, E2
Hard, ML1
Einarson, TR1
Koren, G1
Obe, G1
Ristow, H1
Goldstein, DB1
O'Shea, KS1
Kaufman, MH1
Szaszovsky, E1
Szaszovszky, E1
Igali, S1
Imrei, J1
Agarwal, DP1
Goedde, HW1
Imai, T1
Omoto, M1
Ylikorkala, O1
Randall, CL2
Ekblad, U1
Anton, RF1
Becker, HC1
Phillips, DK1
Baskin, GS1
Zorzano, A1
Herrera, E1
Khokha, AM1
Ali, F1
Persaud, TV1
Custo, GM1
Mastrofini, P1
Corazzi, L1
Arienti, G1
Suwaki, H1

Reviews

11 reviews available for acetaldehyde and Alcohol Related Neurodevelopmental Disorder

ArticleYear
Cellular and mitochondrial effects of alcohol consumption.
    International journal of environmental research and public health, 2010, Volume: 7, Issue:12

    Topics: Acetaldehyde; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Ethanol; Female; Fetal Alcohol Spec

2010
Determination of maternal-fetal biomarkers of prenatal exposure to ethanol: a review.
    Journal of pharmaceutical and biomedical analysis, 2012, Volume: 69

    Topics: Acetaldehyde; Alanine Transaminase; Alcohol Drinking; Aspartate Aminotransferases; Biomarkers; Eryth

2012
Biochemical markers of alcohol use in pregnant women.
    Clinical biochemistry, 2003, Volume: 36, Issue:1

    Topics: Acetaldehyde; Alcohol Drinking; Alcohols; Biomarkers; Erythrocyte Indices; Female; Fetal Alcohol Spe

2003
Effect of alcohol on the heart and cardiac metabolism.
    Federation proceedings, 1982, Volume: 41, Issue:8

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Calcium; Cell Membrane; Dogs;

1982
[Kinetics and teratogenic action of ethyl alcohol].
    Akusherstvo i ginekologiia, 1981, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Alcohol Oxidoreductases; Animals; Biotransformatio

1981
Mutagenic, cancerogenic and teratogenic effects of alcohol.
    Mutation research, 1979, Volume: 65, Issue:4

    Topics: Acetaldehyde; Adult; Alcoholism; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; Drosophi

1979
Medicobiological and genetic studies on alcoholism. Role of metabolic variation and ethnicity on drinking habits, alcohol abuse and alcohol-related mortality.
    The Clinical investigator, 1992, Volume: 70, Issue:6

    Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Central Nervous System; Diseases in Twins; Ethanol; Feta

1992
Perspectives on the pathophysiology of fetal alcohol syndrome.
    Alcoholism, clinical and experimental research, 1990, Volume: 14, Issue:6

    Topics: Acetaldehyde; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetal Growth Retardation;

1990
Fetal alcohol syndrome: current status of pathogenesis.
    Alcoholism, clinical and experimental research, 1990, Volume: 14, Issue:5

    Topics: Acetaldehyde; Animals; Dose-Response Relationship, Drug; Ethanol; Female; Fetal Alcohol Spectrum Dis

1990
[Pathogenesis of the fetal alcohol syndrome].
    Akusherstvo i ginekologiia, 1988, Issue:1

    Topics: Acetaldehyde; Alcoholism; Female; Fetal Alcohol Spectrum Disorders; Humans; Placenta; Pregnancy; Pre

1988
Alcohol and alcohol problems research 2. Japan.
    British journal of addiction, 1985, Volume: 80, Issue:2

    Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Female; Fetal Alcohol Spectrum D

1985

Other Studies

32 other studies available for acetaldehyde and Alcohol Related Neurodevelopmental Disorder

ArticleYear
Metabolism: alcohol, DNA and disease.
    Nature, 2011, Jul-06, Volume: 475, Issue:7354

    Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Anima

2011
Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.
    Nature, 2011, Jul-06, Volume: 475, Issue:7354

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Alleles; Ani

2011
Neurotoxic effects of alcohol and acetaldehyde during embryonic development.
    Journal of toxicology and environmental health. Part A, 2005, Dec-10, Volume: 68, Issue:23-24

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaldehyde; Animals; Antioxidants; Catalase; Cells, Cultured; Deoxygu

2005
Fetal abnormality and maternal ethanol metabolism.
    Lancet (London, England), 1983, Jul-02, Volume: 2, Issue:8340

    Topics: Acetaldehyde; Alcoholism; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Maternal-Fetal

1983
Acetaldehyde and the fetal alcohol syndrome.
    Lancet (London, England), 1983, Jul-23, Volume: 2, Issue:8343

    Topics: Acetaldehyde; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Infant, Newborn; Maternal-F

1983
Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde.
    Toxicology and applied pharmacology, 1984, Volume: 72, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals;

1984
Effect of acetaldehyde on skeletogenesis in rats.
    Drug and alcohol dependence, 1984, Volume: 14, Issue:2

    Topics: Acetaldehyde; Animals; Bone and Bones; Bone Development; Female; Fetal Alcohol Spectrum Disorders; G

1984
Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 2. Pharmacokinetics of the placental transfer of ethanol and acetaldehyde.
    Toxicology and applied pharmacology, 1984, Volume: 72, Issue:2

    Topics: Acetaldehyde; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetal Blood; Fomepizole; K

1984
Teratogenicity of acetaldehyde in vitro: relevance to the fetal alcohol syndrome.
    Life sciences, 1983, Jun-06, Volume: 32, Issue:23

    Topics: Acetaldehyde; Animals; Dose-Response Relationship, Drug; Ethanol; Female; Fetal Alcohol Spectrum Dis

1983
Some teratogenic properties of ethanol and acetaldehyde in C57BL/6J mice: implications for the study of the fetal alcohol syndrome.
    Teratology, 1983, Volume: 27, Issue:2

    Topics: Acetaldehyde; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Mice; Mice, Inbred C57BL;

1983
Maternal ethanol exposure induces transient impairment of umbilical circulation and fetal hypoxia in monkeys.
    Science (New York, N.Y.), 1982, Nov-12, Volume: 218, Issue:4573

    Topics: Acetaldehyde; Animals; Disease Models, Animal; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fe

1982
Teratogenic effects of acetaldehyde in the rat.
    Drug and alcohol dependence, 1982, Volume: 9, Issue:4

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Bone and Bones; Dose-Response Relationship, Drug

1982
Alcohol embryopathy: some facts and speculations about pathogenesis.
    Neurobehavioral toxicology and teratology, 1981,Summer, Volume: 3, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcoholic Beverages; Alcoholism; Brain; Child; Child, Pre

1981
[Fetal alcohol syndrome].
    Akusherstvo i ginekologiia, 1981, Issue:1

    Topics: Acetaldehyde; Adult; Alcoholism; Chromatography, Gas; Ethanol; Female; Fetal Alcohol Spectrum Disord

1981
[Embryotoxic effect of ethanol and its biotransformation products in cultures of postimplantation rat embryos].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:12

    Topics: Acetaldehyde; Animals; Biotransformation; Culture Techniques; Embryonic Development; Ethanol; Female

1981
[Development of the fetal alcohol syndrome].
    Orvosi hetilap, 1980, Jan-20, Volume: 121, Issue:3

    Topics: Acetaldehyde; Alcoholism; Disulfiram; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Inf

1980
Alcohol and pregnancy--part 1: animal data.
    Food and cosmetics toxicology, 1980, Volume: 18, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcohol Drinking; Animals; Brain; Ethanol; Female; Fetal

1980
Protective effect of Liv.52 on alcohol-induced fetotoxicity.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:5

    Topics: Acetaldehyde; Amniotic Fluid; Animals; Body Weight; Drug Combinations; Ethanol; Female; Fetal Alcoho

1993
Catalase mediates acetaldehyde formation from ethanol in fetal and neonatal rat brain.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:6

    Topics: Acetaldehyde; Animals; Brain; Catalase; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Gestation

1997
The prenatal detection of significant alcohol exposure with maternal blood markers.
    The Journal of pediatrics, 1998, Volume: 133, Issue:3

    Topics: Acetaldehyde; Adult; Alcohol Drinking; Biomarkers; Birth Weight; Body Height; Erythrocyte Indices; E

1998
Mean cell volume and gamma-glutamyl transferase are superior to carbohydrate-deficient transferrin and hemoglobin-acetaldehyde adducts in the follow-up of pregnant women with alcohol abuse.
    Acta obstetricia et gynecologica Scandinavica, 2000, Volume: 79, Issue:5

    Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcohol-Related Disorders; Area Under Curve; Erythrocyte Indi

2000
The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure.
    Therapeutic drug monitoring, 2001, Volume: 23, Issue:4

    Topics: Acetaldehyde; Alcoholism; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Incidence; Infa

2001
Fetal-alcohol syndrome in child whose parents had stopped drinking.
    Lancet (London, England), 1979, Jul-07, Volume: 2, Issue:8132

    Topics: Acetaldehyde; Alcohol Drinking; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans;

1979
Some promising fields of inquiry in biomedical alcohol research.
    Journal of studies on alcohol. Supplement, 1979, Volume: 8

    Topics: Acetaldehyde; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholism; Animals; Female; Fetal Alcohol

1979
The teratogenic effect of acetaldehyde: implications for the study of the fetal alcohol syndrome.
    Journal of anatomy, 1979, Volume: 128, Issue:Pt 1

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Body Weight; Central Nervous System; Dose-Respon

1979
Maternal alcohol consumption and birth weight.
    British medical journal, 1978, Nov-11, Volume: 2, Issue:6148

    Topics: Acetaldehyde; Alcohol Drinking; Birth Weight; Female; Fetal Alcohol Spectrum Disorders; Humans; Preg

1978
The fetal alcohol syndrome: symptoms and pathogenesis.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1978, Volume: 19, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Aldehyde Oxidoreductases; Animals; Child, Preschoo

1978
[Effects of acetaldehyde exposure on maternal rats and their offspring].
    Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence, 1992, Volume: 27, Issue:3

    Topics: Acetaldehyde; Animals; Body Weight; Brain; Female; Fetal Alcohol Spectrum Disorders; Fetal Organ Mat

1992
Hemoglobin-acetaldehyde adducts are elevated in women carrying alcohol-damaged fetuses.
    Alcoholism, clinical and experimental research, 1991, Volume: 15, Issue:6

    Topics: Acetaldehyde; Alcohol Drinking; Birth Weight; Dose-Response Relationship, Drug; Female; Fetal Alcoho

1991
Decreased in vivo rate of ethanol metabolism in the suckLing rat.
    Alcoholism, clinical and experimental research, 1989, Volume: 13, Issue:4

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Animals, Suckling; Ethanol; Fe

1989
Mechanisms of fetal alcohol effects: role of acetaldehyde.
    Experimental pathology, 1988, Volume: 33, Issue:1

    Topics: Acetaldehyde; Animals; Cyanamide; Embryo Loss; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Pr

1988
[Role of ethanol in perinatal pathology].
    Minerva ginecologica, 1986, Volume: 38, Issue:5

    Topics: Acetaldehyde; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetus; Guinea Pigs; Humans

1986