acetaldehyde has been researched along with Alcohol Abuse in 503 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This account of recent work presented at the 4th International Symposium on Alcohol Pancreatitis and Cirrhosis reports animal studies aimed at determining the role of the "acetaldehyde burst," generated shortly upon ethanol intake, as the mechanism of protection against alcoholism conferred by the ADH1B*2 polymorphism." | 8.87 | Acetaldehyde burst protection of ADH1B*2 against alcoholism: an additional hormesis protection against esophageal cancers following alcohol consumption? ( Israel, Y; Quintanilla, ME; Rivera-Meza, M; Sapag, A; Tampier, L, 2011) |
| " We investigated whether variation in genes encoding cytochrome P450 2E1 (CYP2E1) or acetaldehyde-metabolising enzymes (ALDH1A1, ALDH2) might alter the risk of AD, with and without symptoms of anxiety, in a Cape population with mixed ancestry." | 7.80 | Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population. ( Crawford, A; Dalvie, S; Fein, G; King, A; Koenen, K; Lewis, S; Liberzon, I; Ramesar, R; Stein, DJ, 2014) |
| " Based on these results, alcoholism or alcohol abuse might be predicted by concentration of acetaldehyde as well as methanol during abstinence." | 7.75 | Use of acetaldehyde and methanol as markers of alcohol abuse and their measurement. ( Tominaga, Y, 2009) |
| " A role of acetaldehyde is implied in these effects, which seem to override the usual discomfort effects associated with protection against alcohol drinking." | 7.73 | Acetaldehyde involvement in positive and negative alcohol expectancies in han Chinese persons with alcoholism. ( Hahn, CY; Hsieh, CH; Huang, SY; Ko, HC; Lee, IH; Lee, JF; Lin, WW; Lu, RB; Yang, YK; Yeh, TL, 2006) |
| "The ALDH2*2 allele has been shown to be a protective factor against alcoholism in a normal population owing in part to the elevated blood level of acetaldehyde and its accompanying physiological discomforts after drinking alcohol." | 7.73 | Acetaldehyde involvement in positive and negative alcohol expectancies in han Chinese persons with alcoholism. ( Hahn, CY; Hsieh, CH; Huang, SY; Ko, HC; Lee, IH; Lee, JF; Lin, WW; Lu, RB; Yang, YK; Yeh, TL, 2006) |
| "While the immunoreactive acetaldehyde adducts were found to be increased in 50% of the alcohol abusers (p less than 0." | 7.68 | Hemoglobin-acetaldehyde adducts in human alcohol abusers. ( Israel, Y; Niemelä, O, 1992) |
| "Acetaldehyde (AA), the first product of ethanol metabolism, has been suggested as an important mediator in alcoholic pancreatitis, but experimental evidence has not been convincing." | 7.68 | The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis. ( Cameron, JL; MacGowan, S; Nordback, IH; Potter, JJ, 1991) |
| "The development of histaminergic pathways has been studied in the rat brain specially as influenced by maternal alcoholism." | 7.66 | Development of histaminergic pathways in brain as influenced by maternal alcoholism. ( Rawat, AK, 1980) |
| "The plasma pyridoxal-5'-phosphate (PLP) level of alcoholic subjects has been compared with that of non-alcoholic individuals in order to ascertain the incidence of abnormal vitamin B(6) metabolism in chronic alcohol abuse." | 7.65 | Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes. ( Li, TK; Lumeng, L, 1974) |
| "Acetaldehyde levels were found to be significantly higher in alcoholics than in the volunteers for the period of 2 to 3 months after admission." | 5.35 | Use of acetaldehyde and methanol as markers of alcohol abuse and their measurement. ( Tominaga, Y, 2009) |
| "Based on these results, alcoholism or alcohol abuse might be predicted by concentration of acetaldehyde as well as methanol during abstinence." | 5.35 | Use of acetaldehyde and methanol as markers of alcohol abuse and their measurement. ( Tominaga, Y, 2009) |
| "Separately, using the key words fetal alcohol syndrome, epidemiology, prevalence, incidence, and frequency, articles were identified reporting ARBD incidences among the offspring of heavy drinkers." | 5.31 | The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure. ( Einarson, TR; Hard, ML; Koren, G, 2001) |
| "Acetaldehyde is a toxic substance common to heavy drinking of alcohol and heavy smoking of cigarettes." | 5.25 | Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking. ( Gonzales, LJ; Parker, CM; Smith, GG; Sprince, H, 1975) |
| "This account of recent work presented at the 4th International Symposium on Alcohol Pancreatitis and Cirrhosis reports animal studies aimed at determining the role of the "acetaldehyde burst," generated shortly upon ethanol intake, as the mechanism of protection against alcoholism conferred by the ADH1B*2 polymorphism." | 4.87 | Acetaldehyde burst protection of ADH1B*2 against alcoholism: an additional hormesis protection against esophageal cancers following alcohol consumption? ( Israel, Y; Quintanilla, ME; Rivera-Meza, M; Sapag, A; Tampier, L, 2011) |
| "Studies over the past two decades have indicated that protein modifications by acetaldehyde, the first metabolite of ethanol, are generated in the circulation as a result of alcohol abuse and play a major role in the pathogenesis of ethanol-induced diseases." | 4.84 | Acetaldehyde adducts in circulation. ( Niemelä, O, 2007) |
| " The presentations were (1) Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotype and cancer risk for upper aerodigestive tract in Japanese alcoholics, by Akira Yokoyama; (2) The role of acetaldehyde in alcohol-associated carcinogenesis, by Nils Homann; (3) High salivary acetaldehyde levels after a moderate dose of alcohol in ALDH2-deficient subjects, by Satu Väkeväinen; (4) Alcohol and vitamin A interactions, by Xian Dong Wang; and (5) Alcohol and colorectal cancer, by Helmut K." | 4.81 | Alcohol and cancer. ( Homann, N; Matsuzaki, S; Seitz, HK; Väkeväinen, S; Wang, XD; Yokoyama, A, 2001) |
| "The ALDH2*1 allele was found as a risk factor for alcohol abuse and ALC, and combined genotypes of ADH1B rs1229984, ADH1C rs698, and ALDH2 rs671 with non-acetaldehyde accumulation increase ALC risk." | 4.31 | Association of ADH1B rs1229984, ADH1C rs698, and ALDH2 rs671 with Alcohol abuse and Alcoholic Cirrhosis in People Living in Northeast Vietnam. ( Bui, HTT; Hoang, YTT; Nguyen, HH; Nguyen, QV; Nguyen, TD; Nguyen, YT; Vu, LT; Vu, NP, 2023) |
| " We investigated whether variation in genes encoding cytochrome P450 2E1 (CYP2E1) or acetaldehyde-metabolising enzymes (ALDH1A1, ALDH2) might alter the risk of AD, with and without symptoms of anxiety, in a Cape population with mixed ancestry." | 3.80 | Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population. ( Crawford, A; Dalvie, S; Fein, G; King, A; Koenen, K; Lewis, S; Liberzon, I; Ramesar, R; Stein, DJ, 2014) |
| "Chronic alcoholism leads to the onset and progression of alcoholic cardiomyopathy through toxic mechanisms of ethanol and its metabolite, acetaldehyde." | 3.75 | Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. ( Doser, TA; Epstein, PN; Li, SY; Ren, J; Thomas, DP; Turdi, S, 2009) |
| " Based on these results, alcoholism or alcohol abuse might be predicted by concentration of acetaldehyde as well as methanol during abstinence." | 3.75 | Use of acetaldehyde and methanol as markers of alcohol abuse and their measurement. ( Tominaga, Y, 2009) |
| "Salsolinol (SAL), a condensation product of dopamine and acetaldehyde that appears in the rat and human brain after ethanol ingestion, has been largely implicated in the aetiology of alcoholism." | 3.75 | Local salsolinol modulates dopamine extracellular levels from rat nucleus accumbens: shell/core differences. ( Granero, L; Hipólito, L; Polache, A; Sánchez-Catalán, MJ, 2009) |
| "Disulfiram, an inhibitor of aldehyde dehydrogenase used in the treatment of alcoholism, is an effective medication when its intake is supervised by a third person." | 3.74 | Tolerance to disulfiram induced by chronic alcohol intake in the rat. ( Israel, Y; Quintanilla, ME; Tampier, L, 2008) |
| "Data presented show that antialcohol drugs that inhibit Aldh2 gene expression can be generated endogenously in liver cells infected by an adenoviral vector carrying an antisense-coding gene, thus mimicking the high-acetaldehyde phenotype that exists in humans carrying the Glu487Lys mutation who are protected against alcoholism." | 3.73 | Aldehyde dehydrogenase (ALDH2) activity in hepatoma cells is reduced by an adenoviral vector coding for an ALDH2 antisense mRNA. ( Israel, Y; Karahanian, E; Ocaranza, P, 2005) |
| " A role of acetaldehyde is implied in these effects, which seem to override the usual discomfort effects associated with protection against alcohol drinking." | 3.73 | Acetaldehyde involvement in positive and negative alcohol expectancies in han Chinese persons with alcoholism. ( Hahn, CY; Hsieh, CH; Huang, SY; Ko, HC; Lee, IH; Lee, JF; Lin, WW; Lu, RB; Yang, YK; Yeh, TL, 2006) |
| "The ALDH2*2 allele has been shown to be a protective factor against alcoholism in a normal population owing in part to the elevated blood level of acetaldehyde and its accompanying physiological discomforts after drinking alcohol." | 3.73 | Acetaldehyde involvement in positive and negative alcohol expectancies in han Chinese persons with alcoholism. ( Hahn, CY; Hsieh, CH; Huang, SY; Ko, HC; Lee, IH; Lee, JF; Lin, WW; Lu, RB; Yang, YK; Yeh, TL, 2006) |
| "Alcohol abuse has been shown to result in the production of antibodies against acetaldehyde-modified epitopes in proteins." | 3.73 | IgAs against acetaldehyde-modified red cell protein as a marker of ethanol consumption in male alcoholic subjects, moderate drinkers, and abstainers. ( Anttila, P; Hietala, J; Koivisto, H; Latvala, J; Niemelä, O, 2006) |
| "Acetaldehyde-derived protein condensates (adducts) have been suggested as promising biological markers of alcohol abuse because they represent actual metabolites of ethanol." | 3.71 | Assays for acetaldehyde-derived adducts in blood proteins based on antibodies against acetaldehyde/lipoprotein condensates. ( Järvi, K; Latvala, J; Makkonen, K; Melkko, J; Niemelä, O; Parkkila, S, 2001) |
| "The effect of low concentrations of acetaldehyde on activated partial thromboplastin time (APTT) and prothrombin time (PT) of Accuclot coagulation plasmas was monitored over a prolonged time to mimic effects observed in alcoholism." | 3.71 | Short- and long-term effects of acetaldehyde on plasma. ( Adamu, MT; Brecher, AS, 2002) |
| "The present study examined whether measurement of hemoglobin-acetaldehyde (HbA1-AcH) using an improved methodology may be useful as a biological marker of alcohol abuse." | 3.70 | Evaluation of acetaldehyde-modified hemoglobin and other markers of chronic heavy alcohol use: effects of gender and hemoglobin concentration. ( Androulakakis, V; Brown, WJ; Hazelett, SE; Jarjoura, D; Liebelt, RA; Truitt, EB, 1998) |
| "Carbohydrate-deficient transferrin (CDT) has emerged as the best new marker for alcohol abuse." | 3.70 | Comparison of carbohydrate-deficient transferrin, immunoglobulin A antibodies reactive with acetaldehyde-modified protein and acetaldehyde-modified albumin with conventional markers of alcohol consumption. ( de Jersey, J; Hurme, L; Seppä, K; Sillanaukee, P; Wilce, PA; Worrall, S, 1998) |
| "The content of endogenic ethanol (EE) and acetaldehyde (AcA) in blood, excretion of catecholamines (CA) with urine and their content in blood, functional activity of vegetative nerve system and central nerve system were studied in patients with chronic alcoholism in the period of short-term remission." | 3.70 | [The characteristics of the metabolic and psychophysiological disorders in patients in different stages of chronic alcoholism]. ( Kharchenko, NK, 1999) |
| "With the ex vivo perfused canine pancreas preparation, the infusion of acetaldehyde, the primary metabolite of ethanol oxidation, plus a short period of ischemia to convert xanthine dehydrogenase to xanthine oxidase, results in the physiologic injury response of acute pancreatitis (edema, weight gain, hyperamylasemia)." | 3.69 | Detailed characterization of experimental acute alcoholic pancreatitis. ( Cameron, JL; Chacko, VP; Nordback, IH; Olson, JL, 1995) |
| " The reactivity of these groups not only has an important role in the maintenance of mechanical strength in collagen fibrils, but can also manifest pathologically in the cases of aging, diabetes (reactivity with a variety of sugars) and alcoholism (reactivity with acetaldehyde)." | 3.69 | The chemical reactivity and structure of collagen studied by neutron diffraction. ( Miller, A; Wess, L; Wess, TJ, 1996) |
| "A fast-eluting minor variant of hemoglobin A, designated as HbA1-AcH, appears elevated after the incubation of red blood cell hemolysates with acetaldehyde (AcH) and has been proposed as a diagnostic marker for alcoholism or as an indicator for heavy drinking." | 3.68 | Improved separation of acetaldehyde-induced hemoglobin. ( Hazelett, SE; Liebelt, RA; Truitt, EB, 1993) |
| "While the immunoreactive acetaldehyde adducts were found to be increased in 50% of the alcohol abusers (p less than 0." | 3.68 | Hemoglobin-acetaldehyde adducts in human alcohol abusers. ( Israel, Y; Niemelä, O, 1992) |
| "We examined the diagnostic value of acetaldehyde-hemoglobin adducts in the detection of heavy drinking and alcoholism." | 3.68 | Acetaldehyde-modified hemoglobin as a marker of alcohol consumption: comparison of two new methods. ( Israel, Y; Koivula, T; Niemela, O; Seppa, K; Sillanaukee, P, 1992) |
| "Acetaldehyde (AA), the first product of ethanol metabolism, has been suggested as an important mediator in alcoholic pancreatitis, but experimental evidence has not been convincing." | 3.68 | The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis. ( Cameron, JL; MacGowan, S; Nordback, IH; Potter, JJ, 1991) |
| "A new biological alcohol marker, the ratio between the acetaldehyde-induced haemoglobin fraction HbA1ach and the glycated haemoglobin fraction HbA1c (HbA1ach/HbA1c), was studied in association with data obtained in a questionnaire, the Malmö modified Michigan alcoholism screening test (Mm-MAST), completed by 270 consecutive middle-aged men participating in a voluntary health screening." | 3.68 | Association of a haemoglobin-acetaldehyde adduct with questionnaire results on heavy drinkers. ( Koivula, T; Seppä, K; Sillanaukee, P, 1991) |
| "The correlation among degrees of alcohol intoxication, facial flushing, blood alcohol concentration (BAC) and blood acetaldehyde level was studied in 117 male alcoholic patients who underwent various tests to assess alcohol influence." | 3.68 | Degrees of alcohol intoxication in 117 hospitalized cases. ( Adachi, J; Fukunaga, T; Imamichi, H; Mizoi, Y; Ogawa, Y; Ueno, Y, 1991) |
| "New results of biomedical research in alcoholism show great interindividual, as well as racial, variability with respect to metabolism of alcohol and its first oxidation product, acetaldehyde." | 3.67 | Biology of disease. Alcoholism and aldehydism: new biomedical concepts. ( Bühler, R; von Wartburg, JP, 1984) |
| "The development of histaminergic pathways has been studied in the rat brain specially as influenced by maternal alcoholism." | 3.66 | Development of histaminergic pathways in brain as influenced by maternal alcoholism. ( Rawat, AK, 1980) |
| " Hypotension and tachycardia often occur when blood acetaldehyde levels increase." | 3.66 | Cardiovascular changes during the calcium carbimide-ethanol interaction. ( Brien, JF; Hemy, M; Maglana, S; Peachey, JE; Robinson, GM, 1981) |
| "Blood acetaldehyde concentrations were significantly elevated after a moderate ethanol dose in 20 healthy young men with alcoholic parents or siblings compared to matched controls with no familial alcoholism." | 3.66 | Ethanol ingestion: differences in blood acetaldehyde concentrations in relatives of alcoholics and controls. ( Rayses, V; Schuckit, MA, 1979) |
| "The plasma pyridoxal-5'-phosphate (PLP) level of alcoholic subjects has been compared with that of non-alcoholic individuals in order to ascertain the incidence of abnormal vitamin B(6) metabolism in chronic alcohol abuse." | 3.65 | Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes. ( Li, TK; Lumeng, L, 1974) |
| " The ADH1B polymorphisms did not appear to correlate with the pharmacokinetic and pharmacodynamic effects." | 2.73 | Pharmacokinetic and pharmacodynamic basis for partial protection against alcoholism in Asians, heterozygous for the variant ALDH2*2 gene allele. ( Chen, YC; Peng, GS; Tsao, TP; Wang, MF; Yin, SJ, 2007) |
| "Alcohol abuse is a serious medical and social problem." | 2.46 | Alcohol and acetaldehyde in public health: from marvel to menace. ( Guo, R; Ren, J, 2010) |
| "Acute alcohol abuse causes damage to and functional impairment of several organs affecting protein, carbohydrate, and fat metabolism." | 2.46 | Cellular and mitochondrial effects of alcohol consumption. ( Manzo-Avalos, S; Saavedra-Molina, A, 2010) |
| "Alcohol dependence is correlated with a wide spectrum of medical, psychological, behavioral, and social problems." | 2.46 | Cellular and mitochondrial effects of alcohol consumption. ( Manzo-Avalos, S; Saavedra-Molina, A, 2010) |
| "Alcoholism is a complex behavioural disorder." | 2.45 | Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2 on blood acetaldehyde concentrations. ( Peng, GS; Yin, SJ, 2009) |
| "Like acetaldehyde, alcohol has been widely considered a nonspecific drug, despite rather persuasive evidence implicating inhibitory GABA(A) receptors (GABA(A)Rs) in acute alcohol actions, for example, a GABA(A)R ligand, the imidazobenzodiazepine Ro15-4513 antagonizes many low-to-moderate dose alcohol actions in mammals." | 2.44 | Physiology and pharmacology of alcohol: the imidazobenzodiazepine alcohol antagonist site on subtypes of GABAA receptors as an opportunity for drug development? ( Olsen, RW; Wallner, M, 2008) |
| " The alpha-dicarbonyl moiety in related substances is believed to induce various toxic responses, such as Alzheimer's disease, mutagenesis, and carcinogenesis." | 2.43 | Role of diacetyl metabolite in alcohol toxicity and addiction via electron transfer and oxidative stress. ( Cooksy, AL; Kovacic, P, 2005) |
| "Although alcohol abuse is known to cause a wide array of adverse effects on blood cell formation, the molecular mechanisms by which alcohol exerts its toxic actions have remained poorly defined." | 2.42 | Alcoholic macrocytosis--is there a role for acetaldehyde and adducts? ( Niemelä, O; Parkkila, S, 2004) |
| "The acetaldehyde adducts allow to detect an alcohol abuse lasting for several weeks, even after a recent alcohol withdrawal." | 2.41 | [Peripheral markers, future perspectives]. ( Nalpas, B; Schellenberg, F, 2001) |
| "Rodd-Henricks; and (4) Salsolinol and alcohol addiction, by William J." | 2.41 | Involvement of acetaldehyde in alcohol addiction. ( Deitrich, RA; Li, TK; McBride, WJ; Rodd-Henricks, ZA; Smith, BR; Zimatkin, S, 2002) |
| "The identification of alcohol abuse is an important social and clinical objective for which various biochemical procedures have been utilized, serum enzymes and circulating proteins being predominant." | 2.39 | Enzymes and circulating proteins as markers of alcohol abuse. ( Goldberg, DM; Kapur, BM, 1994) |
| "After all, in patients with alcohol abuse and myocarditis the immune functioning appears to be compromised." | 2.39 | [Alcohol and myocarditis]. ( Ferency, I; Kaiser, A; Maisch, B; Wilke, A, 1996) |
| "The risk of developing alcoholic cardiomyopathy is related to both the mean daily alcohol intake and the duration of drinking, but there is much individual susceptibility to the toxic effect of alcohol." | 2.39 | [Alcohol and myocarditis]. ( Ferency, I; Kaiser, A; Maisch, B; Wilke, A, 1996) |
| "Screening for alcohol abuse in its early phase, and the diagnosis of alcohol-related organ damage by laboratory tests in clinical settings, have often been unreliable." | 2.39 | The separation of hemoglobin-acetaldehyde adducts by cation exchange chromatography: a brief history. ( Itälä, L; Sillanaukee, P, 1994) |
| " In human volunteers treated with increasing doses of DSF and challenged with ethanol between each of the dosage periods, the mean plasma concentrations of Me-DTC at steady state were proportional to the DSF doses given." | 2.38 | A review of the pharmacokinetics and pharmacodynamics of disulfiram and its metabolites. ( Johansson, B, 1992) |
| "Disulfiram is an irreversible ALDH inhibitor when administered in vivo." | 2.38 | The pharmacology and toxicology of disulfiram and its metabolites. ( Petersen, EN, 1992) |
| "In spite of continuing alcohol abuse, only a fraction of all alcoholics will develop alcoholic hepatitis and eventually cirrhosis." | 2.38 | [Pathogenesis of alcoholic liver disease]. ( Lauterburg, BH, 1992) |
| "Acetaldehyde was found to be transported in the blood mainly bound reversibly to 2 components of the red blood cells (RBC): a) hemoglobin, which provides binding of a high affinity, but low capacity, and b) a non-protein component (presumably cysteine), which has a lower affinity but a higher capacity." | 2.38 | Contribution of exogenous ethanol and endogenous substrates to acetaldehyde-adduct formation in liver injury. ( Baraona, E; Behrens, UJ; Hernández-Muñoz, R; Lieber, CS; Ma, XL; Uppal, R, 1991) |
| "Acetaldehyde also promotes glutathione depletion, free-radical mediated toxicity, lipid peroxidation and hepatic collagen synthesis." | 2.38 | Biochemical mechanisms of alcohol-induced hepatic injury. ( Lieber, CS, 1991) |
| "1." | 2.38 | The genesis of alcoholic brain tissue injury. ( Pratt, OE; Rooprai, HK; Shaw, GK; Thomson, AD, 1990) |
| "When alcohol abuse occurs in association with anxiety, depression, or schizophrenia, treatment with the anxiolytic, antidepressant, and neuroleptic drugs, respectively, may facilitate the alcoholic's ability to participate in other programs." | 2.37 | Pharmacologic treatment of chronic alcoholism. ( Annis, A; Peachey, JE, 1984) |
| "A hereditary element to alcohol dependence has been suggested by several adoption and twin studies, but the many contradictions between research results emphasise that any genetic contribution is overshadowed by socio-cultural factors." | 2.37 | Psychiatric advances in the understanding and treatment of alcohol dependence. ( Madden, JS, 1984) |
| "Acetaldehyde is a very toxic substance the removal of which makes possible the consumption of large quantities of ethanol frequently imbibed by alcoholics." | 2.37 | Genetic variability of enzymes of alcohol metabolism in human beings. ( Bosron, WF; Li, TK, 1986) |
| "Acetaldehyde has been found to form adducts with human hemoglobin, a portion of which (15-25%) are stable to dialysis." | 2.37 | Clinical implications of acetaldehyde adducts with hemoglobin. ( Nguyen, LB; Peterson, CM, 1985) |
| "Patients with alcohol use disorders have higher odds of COVID-19-associated hospitalization and mortality." | 1.91 | Malondialdehyde acetaldehyde adduction of surfactant protein D attenuates SARS-CoV-2 spike protein binding and virus neutralization. ( Bailey, KL; Bauer, C; Katafiasz, DM; Morwitzer, MJ; Muralidharan, A; Oyewole, OO; Pham, D; Reid, SP; Roy, E; Wyatt, TA, 2023) |
| "GGT indicates Alcohol Abuse only in background of normal LFT." | 1.72 | Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease. ( BhatB, NM, 2022) |
| "24% were in steatosis,32% were in steatohepatitis, while 44% were in cirrhosis." | 1.72 | Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease. ( BhatB, NM, 2022) |
| " While the pharmacokinetics of ethanol metabolism through alcohol dehydrogenase have been thoroughly explored in previous studies, in this paper, we combined a base physiologically-based pharmacokinetic (PBPK) model with a whole-body genome-scale model (WBM) to gain further insight into the effect of other less explored processes and genetic variations on ethanol metabolism." | 1.62 | Integration of a physiologically-based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for characterization of ethanol and acetaldehyde metabolism. ( Mahadevan, R; Pei, W; Thiele, I; Zhu, L, 2021) |
| "Disulfiram is an adjunct in the treatment of alcohol use disorders, but case reports indicate that disulfiram ethanol reactions are not always recognized in the emergency department." | 1.56 | Recognition of a disulfiram ethanol reaction in the emergency department is not always straightforward. ( Buylaert, W; Chys, S; De Paepe, P; Desmet, T; Huys, L; Segher, K; Steen, E, 2020) |
| "Heavy drinking leads to premature aging and precipitates the onset of age-related diseases." | 1.51 | Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde. ( Hara, S; Higuchi, S; Hishimoto, A; Matsushita, S; Yamaki, N; Yokoyama, A, 2019) |
| "As such, lungs of individuals with alcohol use disorders (AUDs) are a target for the effects of combined alcohol and cigarette smoke metabolites." | 1.46 | Malondialdehyde-Acetaldehyde (MAA) Protein Adducts Are Found Exclusively in the Lungs of Smokers with Alcohol Use Disorders and Are Associated with Systemic Anti-MAA Antibodies. ( Burnham, EL; DeVasure, JM; Duryee, MJ; Hunter, CD; Kharbanda, KK; Klassen, LW; Sapkota, M; Sisson, JH; Sweeter, JM; Thiele, GM; Wyatt, TA, 2017) |
| "The pathogenesis of ethanol-related colorectal cancer (ER-CRC) is thought to be partly mediated by gut microbes." | 1.43 | Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer. ( Aoki, Y; Hattori, M; Inai, M; Kinoshita, K; Kuwahara, A; Mizukami, T; Morita, H; Nakayama, T; Oshima, K; Saito, Y; Shimoyama, T; Suda, W; Suga, S; Suwa, Y; Takahashi, S; Totsuka, Y; Tsubo, T; Tsuruya, A; Tsutsumi, E; Yamaguchi, H; Yokoyama, A, 2016) |
| "Associations between alcohol dependence and polymorphisms in ADH1B, ADH1C, and ALDH2 were compared in a community sample of Native Americans (n 791) living on reservations and Mexican Americans (n 391) living within the same county." | 1.38 | ADH and ALDH polymorphisms and alcohol dependence in Mexican and Native Americans. ( Ehlers, CL; Gizer, IR; Liang, T, 2012) |
| "No associations between alcohol dependence and polymorphisms in ADH1C were found." | 1.38 | ADH and ALDH polymorphisms and alcohol dependence in Mexican and Native Americans. ( Ehlers, CL; Gizer, IR; Liang, T, 2012) |
| "We develop a pharmacokinetic model describing how genetic variations in ADH1B, ADH1C, ADH7, ALDH2, and TAS2R38 affect consumption behavior, and alcohol and acetaldehyde levels over time in various tissues of individuals with a particular genotype to predict their susceptibility to alcohol dependence." | 1.36 | Using a pharmacokinetic model to relate an individual's susceptibility to alcohol dependence to genotypes. ( Kidd, KK; Miller, P; Mustavich, LF; Zhao, H, 2010) |
| "We describe an approach for alcohol dependence connecting a mechanistic model at the molecular level with disease risk at the population level, and investigate how this model implies statistical gene-gene interactions that affect disease risk." | 1.36 | Using a pharmacokinetic model to relate an individual's susceptibility to alcohol dependence to genotypes. ( Kidd, KK; Miller, P; Mustavich, LF; Zhao, H, 2010) |
| "Chronic alcohol consumption led to cardiac hypertrophy, reduced fractional shortening, cell shortening, and impaired intracellular Ca(2+) homeostasis, the effect of which was alleviated by ALDH2." | 1.35 | Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. ( Doser, TA; Epstein, PN; Li, SY; Ren, J; Thomas, DP; Turdi, S, 2009) |
| "Acetaldehyde levels were found to be significantly higher in alcoholics than in the volunteers for the period of 2 to 3 months after admission." | 1.35 | Use of acetaldehyde and methanol as markers of alcohol abuse and their measurement. ( Tominaga, Y, 2009) |
| "Based on these results, alcoholism or alcohol abuse might be predicted by concentration of acetaldehyde as well as methanol during abstinence." | 1.35 | Use of acetaldehyde and methanol as markers of alcohol abuse and their measurement. ( Tominaga, Y, 2009) |
| "Hypertension is commonly observed in alcoholics." | 1.35 | Effect of acetaldehyde upon cathepsin G and chymase. NRAS implications. ( Brecher, AS; Dubord, R, 2008) |
| "The National Institute on Alcohol Abuse and Alcoholism, Office of Dietary Supplements, Office of Rare Diseases, National Cancer Institute, National Institute on Drug Abuse, and National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, sponsored an international symposium on Mechanisms of Alcohol-Associated Cancers in Bethesda, Maryland, USA, October 2004." | 1.33 | Mechanisms of alcohol-associated cancers: introduction and summary of the symposium. ( Khalsa, J; Purohit, V; Serrano, J, 2005) |
| "We propose that the structural epitope AA-AGE is an important toxic moiety for neuronal cells in alcoholism." | 1.33 | Cytotoxicity of acetaldehyde-derived advanced glycation end-products (AA-AGE) in alcoholic-induced neuronal degeneration. ( Saito, T; Takeuchi, M, 2005) |
| "Alcohol abuse has been shown to result in the production of antibodies against acetaldehyde-modified epitopes in proteins." | 1.33 | IgAs against acetaldehyde-modified red cell protein as a marker of ethanol consumption in male alcoholic subjects, moderate drinkers, and abstainers. ( Anttila, P; Hietala, J; Koivisto, H; Latvala, J; Niemelä, O, 2006) |
| " We propose that the structural epitope AA-AGE is an important toxic moiety for neuronal cells in alcoholism." | 1.32 | Neurotoxicity of acetaldehyde-derived advanced glycation end products for cultured cortical neurons. ( Ashizawa, T; Bucala, R; Choei, H; Inagaki, Y; Iwaki, M; Kameda, Y; Kikuchi, S; Riederer, P; Saito, T; Sasaki, N; Takeuchi, M; Watai, T; Yamagishi, S, 2003) |
| "As acetaldehyde seems to be a carcinogenic factor associated with chronic alcohol consumption, alcoholics with the alcohol dehydrogenase (ADH) 1C*1 allele seem to be particularly at risk as this allele encodes for a rapidly ethanol metabolising enzyme leading to increased acetaldehyde levels." | 1.32 | Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde. ( Benesova, M; Conradt, C; Götte, K; Homann, N; Hörrmann, K; Inoue, H; Li, J; Salaspuro, M; Seitz, HK; Tisch, M; Väkeväinen, S; Visapää, JP, 2004) |
| "Alcohol addiction was diagnosed according to ICD-10 criteria." | 1.32 | [Acetaldehyde concentration in acute ethanol-intoxicated patients addicted to alcohol]. ( Gawlikowski, T; Gomółka, E; Król, A; Piekoszewski, W, 2004) |
| "Separately, using the key words fetal alcohol syndrome, epidemiology, prevalence, incidence, and frequency, articles were identified reporting ARBD incidences among the offspring of heavy drinkers." | 1.31 | The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure. ( Einarson, TR; Hard, ML; Koren, G, 2001) |
| "Oral cancer and alcoholic cirrhosis are relatively common diseases encountered in medical and dental practices." | 1.31 | Chronic alcoholism: a common risk factor in oral cancer and alcoholic cirrhosis. ( Perkins, I; Perkins, TM, 2001) |
| "A major risk factor common to both oral cancer and alcoholic cirrhosis is the excessive use of alcohol." | 1.31 | Chronic alcoholism: a common risk factor in oral cancer and alcoholic cirrhosis. ( Perkins, I; Perkins, TM, 2001) |
| "Alcohol abuse is commonly associated with reduced bone mass and osteoporosis as a consequence of both systemic and direct cellular effects." | 1.30 | Ethanol and acetaldehyde inhibit the formation of early osteoblast progenitors in murine and human bone marrow cultures. ( Girasole, G; Giuliani, N; Passeri, G; Pedrazzoni, M; Vescovi, PP, 1999) |
| " However, differences in dose-response patterns for suppression of cytokine gene expression and suppression of the AFC response suggest the involvement of additional factors." | 1.29 | Mechanisms of ethanol-induced suppression of a primary antibody response in a mouse model for binge drinking. ( Han, YC; Pruett, SB, 1995) |
| "The aim of this study was to evaluate the adverse effects on the exocrine pancreas of ethanol and ethanol with congeners which coexist in alcoholic beverages most commonly consumed by the Portuguese population." | 1.29 | [The effect of combined toxicity on the development of alcoholic pancreatic lesions. A long-term experimental trial]. ( Baptista, A; Peneda, J, 1995) |
| "Alcohol abuse is known to cause disturbances to iron homeostasis in man and is associated with elevated serum ferritin levels." | 1.29 | Effect of chronic alcohol feeding on hepatic iron status and ferritin uptake by rat hepatocytes. ( Loney, LA; Potter, BJ; Zhang, H, 1993) |
| "[14C]acetaldehyde (AcH)-Hb was synthesized in vivo for use as a standard." | 1.28 | The identification and partial characterization of acetaldehyde adducts of hemoglobin occurring in vivo: a possible marker of alcohol consumption. ( Belcher, JD; Gapstur, SM; Gross, MD; Potter, JD; Scanlan, G, 1992) |
| "How the levels of rat cardiac, adrenal, and epinephrine and norepinephrine change with acetaldehyde and ethanol given alone or in combination during their acute and chronic administration was examined." | 1.28 | [Acetaldehyde in the cardiotoxic mechanism of action of alcohol: effects on cardiac and adrenal catecholamines]. ( Boĭko, TP; Bozhko, GKh, 1991) |
| "The results indicate that in man, alcohol abuse is connected with reduced activities of several glycosyltransferases in serum, which may reflect an important mechanism behind the carbohydrate deficiencies in secretory as well as membrane-bound glyconjugates in alcoholic patients." | 1.28 | Glycoprotein glycosyltransferase activities in serum in alcohol-abusing patients and healthy controls. ( Borg, S; Stibler, H, 1991) |
| "Facial flushing was recognized in 75% of the subjects." | 1.28 | Degrees of alcohol intoxication in 117 hospitalized cases. ( Adachi, J; Fukunaga, T; Imamichi, H; Mizoi, Y; Ogawa, Y; Ueno, Y, 1991) |
| " Our purpose was to study the binding of acetaldehyde to liver microsomal proteins, a site of ethanol oxidation via cytochrome P-450 (especially P-450 II E1), after chronic administration of ethanol or acetaldehyde for 21 days to rats." | 1.28 | Ethanol-inducible cytochrome P-450 activity and increase in acetaldehyde bound to microsomes after chronic administration of acetaldehyde or ethanol. ( De Saint Blanquat, G; Lamboeuf, Y; Lucas, D; Menez, JF, 1990) |
| "The results suggest that in chronic alcohol abuse, the placenta plays a negligible role in the metabolism of ethanol and acetaldehyde." | 1.28 | Placental alcohol metabolism in chronic alcohol abuse. ( Andersson, S; Halmesmäki, E; Koivusalo, M; Lapatto, R; Ylikorkala, O, 1989) |
| "Evidence is growing that acetaldehyde is responsible for some toxic effects after ethanol intake." | 1.27 | The polymorphisms of alcohol and aldehyde dehydrogenase and their significance for acetaldehyde toxicity. ( Bühler, R; Maring, JA; Pestalozzi, D; Von Wartburg, JP, 1983) |
| "The mechanism by which alcohol abuse causes the morphologic abnormalities is not known." | 1.27 | Red cell morphology in alcoholics: a new test for alcohol abuse. ( Bailey, AR; Homaidan, FR; Kricka, LJ; Whitehead, TP, 1986) |
| "Acetaldehyde was then taken up by extra-splanchnic tissues from both plasma and erythrocytes." | 1.27 | Transport of acetaldehyde in red blood cells. ( Baraona, E; DiPadova, C; Lieber, CS; Tabasco, J, 1987) |
| "This taurine pretreatment produced a 4-fold increase in liver taurine content." | 1.27 | Lowering of liver acetaldehyde but not ethanol concentrations by pretreatment with taurine in ethanol-loaded rats. ( Hobara, N; Nagashima, H; Watanabe, A, 1985) |
| "Blood AcH in occasional or chronic alcohol abusers were generally low (< 10 microM), elevated AcH levels being observed only in association with clinical abnormalities." | 1.26 | Low acetaldehyde levels in blood, breath and cerebrospinal fluid of intoxicated humans as assayed by improved methods. ( Hillbom, M; Lindros, KO; Salaspuro, M; Stowell, A, 1980) |
| "Acetaldehyde is a toxic substance common to heavy drinking of alcohol and heavy smoking of cigarettes." | 1.25 | Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking. ( Gonzales, LJ; Parker, CM; Smith, GG; Sprince, H, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 259 (51.49) | 18.7374 |
| 1990's | 122 (24.25) | 18.2507 |
| 2000's | 76 (15.11) | 29.6817 |
| 2010's | 36 (7.16) | 24.3611 |
| 2020's | 10 (1.99) | 2.80 |
| Authors | Studies |
|---|---|
| BhatB, NM | 1 |
| McQuillan, MA | 1 |
| Ranciaro, A | 1 |
| Hansen, MEB | 1 |
| Fan, S | 1 |
| Beggs, W | 1 |
| Belay, G | 1 |
| Woldemeskel, D | 1 |
| Tishkoff, SA | 1 |
| Muralidharan, A | 1 |
| Bauer, C | 1 |
| Katafiasz, DM | 1 |
| Pham, D | 1 |
| Oyewole, OO | 1 |
| Morwitzer, MJ | 1 |
| Roy, E | 1 |
| Bailey, KL | 2 |
| Reid, SP | 1 |
| Wyatt, TA | 3 |
| Niemelä, O | 14 |
| Halkola, AS | 1 |
| Bloigu, A | 1 |
| Bloigu, R | 1 |
| Nivukoski, U | 1 |
| Pohjasniemi, H | 1 |
| Kultti, J | 1 |
| Prokopieva, VD | 2 |
| Vetlugina, TP | 1 |
| Hoang, YTT | 1 |
| Nguyen, YT | 1 |
| Vu, LT | 1 |
| Bui, HTT | 1 |
| Nguyen, QV | 1 |
| Vu, NP | 1 |
| Nguyen, TD | 1 |
| Nguyen, HH | 1 |
| Guillot, A | 1 |
| Ren, T | 1 |
| Jourdan, T | 1 |
| Pawlosky, RJ | 1 |
| Han, E | 1 |
| Kim, SJ | 1 |
| Zhang, L | 1 |
| Koob, GF | 1 |
| Gao, B | 1 |
| Segher, K | 1 |
| Huys, L | 1 |
| Desmet, T | 1 |
| Steen, E | 1 |
| Chys, S | 1 |
| Buylaert, W | 1 |
| De Paepe, P | 1 |
| Warren, KJ | 1 |
| Wetzel, TJ | 1 |
| Suwondo, T | 1 |
| Rensch, GP | 1 |
| DeVasure, JM | 3 |
| Mosley, DD | 1 |
| Kharbanda, KK | 2 |
| Thiele, GM | 6 |
| Burnham, EL | 2 |
| Yeligar, SM | 1 |
| Shiba, S | 1 |
| Nakamoto, N | 1 |
| Chu, PS | 1 |
| Ojiro, K | 1 |
| Taniki, N | 1 |
| Yamaguchi, A | 1 |
| Morikawa, R | 1 |
| Katayama, T | 1 |
| Yoshida, A | 1 |
| Aoki, R | 1 |
| Teratani, T | 1 |
| Suzuki, T | 1 |
| Miyamoto, T | 1 |
| Hara, S | 2 |
| Yokoyama, A | 14 |
| Kanai, T | 1 |
| Zhu, L | 1 |
| Pei, W | 1 |
| Thiele, I | 1 |
| Mahadevan, R | 1 |
| Sanchez, AC | 1 |
| Li, C | 1 |
| Andrews, B | 1 |
| Asenjo, JA | 1 |
| Samulski, RJ | 1 |
| Sapkota, M | 1 |
| Sweeter, JM | 1 |
| Hunter, CD | 1 |
| Duryee, MJ | 1 |
| Klassen, LW | 5 |
| Sisson, JH | 1 |
| Yamaki, N | 1 |
| Matsushita, S | 4 |
| Hishimoto, A | 1 |
| Higuchi, S | 5 |
| Catazaro, JR | 1 |
| Brecher, AS | 7 |
| Orrico, A | 1 |
| Hipólito, L | 3 |
| Sánchez-Catalán, MJ | 2 |
| Martí-Prats, L | 1 |
| Zornoza, T | 1 |
| Granero, L | 3 |
| Polache, A | 3 |
| Crawford, A | 1 |
| Dalvie, S | 1 |
| Lewis, S | 1 |
| King, A | 1 |
| Liberzon, I | 1 |
| Fein, G | 1 |
| Koenen, K | 1 |
| Ramesar, R | 1 |
| Stein, DJ | 1 |
| Karahanian, E | 3 |
| Rivera-Meza, M | 4 |
| Tampier, L | 7 |
| Quintanilla, ME | 7 |
| Herrera-Marschitz, M | 2 |
| Israel, Y | 14 |
| Guo, R | 2 |
| Xu, X | 1 |
| Babcock, SA | 1 |
| Zhang, Y | 1 |
| Ren, J | 3 |
| van Zyl, PM | 1 |
| Joubert, G | 1 |
| Lachenmeier, DW | 3 |
| Gill, JS | 1 |
| Chick, J | 1 |
| Rehm, J | 3 |
| Zakhari, S | 1 |
| Fois, GR | 1 |
| Diana, M | 3 |
| Tsuruya, A | 1 |
| Kuwahara, A | 1 |
| Saito, Y | 1 |
| Yamaguchi, H | 1 |
| Tsubo, T | 1 |
| Suga, S | 1 |
| Inai, M | 1 |
| Aoki, Y | 1 |
| Takahashi, S | 1 |
| Tsutsumi, E | 3 |
| Suwa, Y | 4 |
| Morita, H | 1 |
| Kinoshita, K | 1 |
| Totsuka, Y | 1 |
| Suda, W | 1 |
| Oshima, K | 1 |
| Hattori, M | 1 |
| Mizukami, T | 1 |
| Shimoyama, T | 1 |
| Nakayama, T | 1 |
| Heit, C | 1 |
| Eriksson, P | 1 |
| Thompson, DC | 1 |
| Charkoftaki, G | 1 |
| Fritz, KS | 1 |
| Vasiliou, V | 1 |
| Han, D | 1 |
| Johnson, HS | 1 |
| Rao, MP | 1 |
| Martin, G | 1 |
| Sancheti, H | 1 |
| Silkwood, KH | 1 |
| Decker, CW | 1 |
| Nguyen, KT | 1 |
| Casian, JG | 1 |
| Cadenas, E | 1 |
| Kaplowitz, N | 1 |
| Orywal, K | 1 |
| Jelski, W | 2 |
| Szmitkowski, M | 2 |
| Deng, XS | 1 |
| Deitrich, RA | 4 |
| Peng, GS | 5 |
| Yin, SJ | 6 |
| Kanteres, F | 1 |
| Brooks, PJ | 1 |
| Enoch, MA | 1 |
| Goldman, D | 1 |
| Li, TK | 5 |
| Doser, TA | 1 |
| Turdi, S | 1 |
| Thomas, DP | 1 |
| Epstein, PN | 1 |
| Li, SY | 1 |
| Tominaga, Y | 2 |
| Sudo, T | 1 |
| Kanegae, T | 2 |
| Nagoya, T | 2 |
| Matsumura, S | 1 |
| Yoshida, M | 1 |
| Teraoka, A | 1 |
| Shimamura, M | 1 |
| Tsukamoto, S | 2 |
| Sato, Y | 1 |
| De Benedetto, GE | 1 |
| Fanigliulo, M | 1 |
| Ganss, S | 1 |
| Rychlak, B | 1 |
| Sulkowska, U | 1 |
| Skiba, M | 1 |
| Zatonski, W | 1 |
| Chen, YC | 2 |
| Tsao, TP | 2 |
| Wang, MF | 4 |
| Lu, RB | 2 |
| Mura, CV | 1 |
| Sapag, A | 2 |
| Melis, M | 1 |
| Enrico, P | 2 |
| Marinelli, M | 1 |
| Brodie, MS | 2 |
| Linneberg, A | 1 |
| Gonzalez-Quintela, A | 1 |
| Vidal, C | 1 |
| Jørgensen, T | 1 |
| Fenger, M | 1 |
| Hansen, T | 1 |
| Pedersen, O | 1 |
| Husemoen, LL | 1 |
| Gomółka, E | 2 |
| Radomska, M | 1 |
| Sulka, A | 1 |
| Imazeki, H | 2 |
| Nakamura, C | 2 |
| Yokoyama, T | 3 |
| Toennes, SW | 1 |
| Wagner, MG | 1 |
| Kauert, GF | 1 |
| Mustavich, LF | 1 |
| Miller, P | 1 |
| Kidd, KK | 1 |
| Zhao, H | 1 |
| Omori, T | 2 |
| Amireche, N | 1 |
| Petit, JS | 1 |
| Bankole, E | 1 |
| Fournet-Fayard, A | 1 |
| Appriou, M | 1 |
| Leon, A | 1 |
| Manzo-Avalos, S | 1 |
| Saavedra-Molina, A | 1 |
| Latino-Martel, P | 1 |
| Arwidson, P | 1 |
| Ancellin, R | 1 |
| Druesne-Pecollo, N | 1 |
| Hercberg, S | 1 |
| Le Quellec-Nathan, M | 1 |
| Le-Luong, T | 1 |
| Maraninchi, D | 1 |
| Mabuchi, R | 1 |
| Kurita, A | 1 |
| Miyoshi, N | 1 |
| Furuta, T | 1 |
| Goda, T | 1 |
| Kan, T | 1 |
| Amagai, T | 1 |
| Ohshima, H | 1 |
| Deehan, GA | 1 |
| Rodd, ZA | 1 |
| Yukawa, Y | 1 |
| Muto, M | 1 |
| Hori, K | 1 |
| Nagayoshi, H | 1 |
| Chiba, T | 1 |
| Matsuda, T | 2 |
| Haas, SL | 1 |
| Ye, W | 1 |
| Löhr, JM | 1 |
| Ehlers, CL | 1 |
| Liang, T | 1 |
| Gizer, IR | 1 |
| Cederbaum, AI | 2 |
| Hurley, TD | 1 |
| Edenberg, HJ | 1 |
| Chen, X | 1 |
| Niu, J | 1 |
| Wang, F | 1 |
| Liu, W | 1 |
| Takeuchi, M | 2 |
| Watai, T | 1 |
| Sasaki, N | 1 |
| Choei, H | 1 |
| Iwaki, M | 1 |
| Ashizawa, T | 1 |
| Inagaki, Y | 1 |
| Yamagishi, S | 1 |
| Kikuchi, S | 1 |
| Riederer, P | 1 |
| Saito, T | 2 |
| Bucala, R | 1 |
| Kameda, Y | 1 |
| VARELA, A | 1 |
| PENNA, A | 1 |
| ALCAINO, F | 1 |
| JOHNSON, E | 1 |
| MARDONES, J | 2 |
| SILVA, P | 1 |
| Nakamura, K | 3 |
| Iwahashi, K | 3 |
| Furukawa, A | 1 |
| Ameno, K | 3 |
| Kinoshita, H | 1 |
| Ijiri, I | 2 |
| Sekine, Y | 1 |
| Suzuki, K | 1 |
| Iwata, Y | 1 |
| Minabe, Y | 1 |
| Mori, N | 1 |
| Ward, RJ | 4 |
| Coutelle, Ch | 1 |
| Adachi, J | 4 |
| Asano, M | 1 |
| Ueno, Y | 2 |
| Ohlendieck, K | 1 |
| Peters, TJ | 6 |
| Preedy, VR | 5 |
| NIBLO, G | 1 |
| NOWINSKI, WW | 1 |
| ROARK, D | 1 |
| Pöschl, G | 1 |
| Stickel, F | 1 |
| Wang, XD | 2 |
| Seitz, HK | 5 |
| Kim, JM | 1 |
| Stewart, R | 1 |
| Shin, IS | 1 |
| Jung, JS | 1 |
| Yoon, JS | 1 |
| Visapää, JP | 1 |
| Götte, K | 1 |
| Benesova, M | 1 |
| Li, J | 1 |
| Homann, N | 2 |
| Conradt, C | 1 |
| Inoue, H | 1 |
| Tisch, M | 1 |
| Hörrmann, K | 1 |
| Väkeväinen, S | 2 |
| Salaspuro, M | 6 |
| Quertemont, E | 1 |
| Parkkila, S | 5 |
| Mochizuki, H | 1 |
| Masaki, T | 1 |
| Kamakura, K | 1 |
| Motoyoshi, K | 1 |
| JACOBSEN, E | 2 |
| LARSEN, V | 3 |
| HALD, J | 2 |
| CARRATLA, R | 1 |
| CARRATALA, R | 1 |
| Gawlikowski, T | 1 |
| Piekoszewski, W | 2 |
| Król, A | 1 |
| Kovacic, P | 1 |
| Cooksy, AL | 1 |
| Purohit, V | 1 |
| Khalsa, J | 1 |
| Serrano, J | 1 |
| Freeman, TL | 1 |
| Tuma, DJ | 6 |
| Worrall, S | 12 |
| Emery, PW | 1 |
| Savolainen, M | 1 |
| Haber, P | 1 |
| Ishii, H | 3 |
| Teschke, R | 4 |
| Moshage, H | 1 |
| Lieber, CS | 31 |
| Wall, TL | 3 |
| Shea, SH | 1 |
| Luczak, SE | 2 |
| Cook, TA | 1 |
| Carr, LG | 1 |
| Ocaranza, P | 1 |
| Dahchour, A | 1 |
| Lallemand, F | 1 |
| De Witte, P | 1 |
| Tyulina, OV | 1 |
| Boldyrev, AA | 1 |
| Johnson, P | 1 |
| Hahn, CY | 1 |
| Huang, SY | 1 |
| Ko, HC | 1 |
| Hsieh, CH | 1 |
| Lee, IH | 1 |
| Yeh, TL | 1 |
| Yang, YK | 1 |
| Lee, JF | 1 |
| Lin, WW | 2 |
| Hietala, J | 1 |
| Koivisto, H | 2 |
| Latvala, J | 2 |
| Anttila, P | 1 |
| Yabushita, H | 1 |
| Kanaly, RA | 1 |
| Shibutani, S | 1 |
| Chrostek, L | 1 |
| Suchocki, EA | 1 |
| Meier, P | 1 |
| Chmiest, W | 1 |
| Targosz, D | 1 |
| Gawlikowsk, T | 1 |
| Singh, AK | 1 |
| Jiang, Y | 1 |
| Benlhabib, E | 1 |
| Gupta, S | 1 |
| Dubord, R | 1 |
| Schoedel, K | 1 |
| Ring, HZ | 1 |
| Katsuyoshi, DM | 1 |
| Tyndale, RF | 1 |
| Sánchez, MJ | 1 |
| McGregor, NR | 1 |
| Peana, AT | 1 |
| Assaretti, AR | 1 |
| Pulighe, E | 1 |
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| Lintas, A | 1 |
| Warnakulasuriya, S | 1 |
| Nagao, T | 1 |
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| Olsen, RW | 1 |
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| Beck, O | 2 |
| Jenkins, WJ | 3 |
| Needham, D | 1 |
| Knop, J | 1 |
| Angelo, H | 1 |
| Christensen, JM | 1 |
| Schuckit, MA | 7 |
| Holman, RB | 1 |
| Véghelyi, PV | 3 |
| Cakebread, K | 1 |
| Palmer, KR | 2 |
| Peachey, JE | 10 |
| Annis, A | 1 |
| Tregear, GW | 1 |
| Coghlan, JP | 1 |
| Behar, D | 1 |
| Berg, CJ | 1 |
| Rapoport, JL | 1 |
| Nelson, W | 1 |
| Linnoila, M | 1 |
| Cohen, M | 1 |
| Bozevich, C | 1 |
| Marshall, T | 1 |
| Tipton, KF | 1 |
| Henehan, GT | 1 |
| McCrodden, JM | 1 |
| Marks, V | 1 |
| Lindros, KO | 5 |
| Nuutinen, H | 1 |
| Zilm, DH | 1 |
| Robinson, GM | 2 |
| Jacob, M | 1 |
| Cappell, H | 1 |
| Von Wartburg, JP | 6 |
| Bühler, R | 2 |
| Maring, JA | 2 |
| Pestalozzi, D | 1 |
| Mizoi, Y | 3 |
| Tatsuno, Y | 1 |
| Kogame, M | 1 |
| Fukunaga, T | 3 |
| Fujiwara, S | 1 |
| Hishida, S | 1 |
| Goedde, HW | 4 |
| Agarwal, DP | 4 |
| Harada, S | 2 |
| Naranjo, CA | 3 |
| García-Buñuel, L | 1 |
| Thurman, RG | 2 |
| Ji, S | 1 |
| Lemasters, JJ | 1 |
| Madden, JS | 1 |
| Lundquist, F | 1 |
| Nuutinen, HU | 1 |
| Salaspuro, MP | 2 |
| Valle, M | 1 |
| van Ieperen, L | 1 |
| Fisher, SE | 1 |
| Atkinson, M | 1 |
| Van Thiel, DH | 3 |
| Nguyen, LB | 2 |
| Peterson, CM | 9 |
| Poldrugo, F | 1 |
| Snead, OC | 1 |
| Weigand, K | 2 |
| Brenner, HD | 1 |
| Takagi, S | 1 |
| Eriksson, CJ | 6 |
| Lamboeuf, Y | 2 |
| la Droitte, P | 1 |
| de Saint-Blanquat, G | 1 |
| Coon, MJ | 1 |
| Koop, DR | 1 |
| Morgan, ET | 1 |
| Korsten, MA | 2 |
| Gordon, ER | 2 |
| Klingenstein, J | 1 |
| Homaidan, FR | 2 |
| Kricka, LJ | 2 |
| Clark, PM | 1 |
| Jones, SR | 1 |
| Whitehead, TP | 2 |
| Sorrell, MF | 5 |
| Gromnatskiĭ, NI | 1 |
| Kulishov, SK | 1 |
| Henderson, GI | 1 |
| Patwardhan, RV | 1 |
| McLeroy, S | 1 |
| Schenker, S | 1 |
| Klatsky, AL | 1 |
| Tomaru, A | 1 |
| Mizorogi, F | 1 |
| Fujita, K | 1 |
| Nishiyama, N | 1 |
| Miura, Y | 1 |
| Matsuda, F | 1 |
| Tanaka, T | 1 |
| Horiguchi, M | 1 |
| Mathews, JD | 1 |
| Khanna, JM | 1 |
| Sellers, EM | 3 |
| Borisov, MM | 2 |
| Brien, JF | 4 |
| Roach, CA | 1 |
| Loomis, CW | 3 |
| Thomas, M | 1 |
| Pardo, MP | 1 |
| Hall, TB | 1 |
| Gavaler, JS | 2 |
| Eagon, PK | 1 |
| Cobb, CF | 1 |
| Chiao, YB | 1 |
| Lester, R | 1 |
| Haddock, NF | 1 |
| Wilkin, JK | 1 |
| Murray, RM | 1 |
| Gurling, HM | 1 |
| Duby, J | 1 |
| Terland, O | 1 |
| Rawat, AK | 3 |
| Demol, P | 1 |
| Andersen, BN | 1 |
| Sarles, H | 1 |
| Boyden, TW | 1 |
| Silvert, MA | 1 |
| Pamenter, RW | 1 |
| Pikkarainen, PH | 1 |
| Lebsack, ME | 1 |
| Korte, A | 1 |
| Obe, G | 3 |
| Ingwersen, I | 1 |
| Rückert, G | 1 |
| Majewski, F | 1 |
| Borisenko, SA | 1 |
| Mannisto, PT | 1 |
| Burov, IuV | 1 |
| Nesterick, CA | 1 |
| Rahwan, RG | 2 |
| Amit, Z | 2 |
| Smith, BR | 2 |
| Brown, ZW | 1 |
| Williams, RL | 1 |
| Leistner, L | 1 |
| Majchrowicz, E | 4 |
| Hunt, WA | 2 |
| McClearn, GE | 1 |
| Stowell, A | 2 |
| Pikkarainen, P | 1 |
| Rothschild, MA | 3 |
| Oratz, M | 3 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Asian Flushing Syndrome With Topical Alpha Agonists[NCT03497442] | Early Phase 1 | 20 participants (Actual) | Interventional | 2018-07-12 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
122 reviews available for acetaldehyde and Alcohol Abuse
| Article | Year |
|---|---|
Features of oxidative stress in alcoholism.
Topics: Acetaldehyde; Alcoholism; Ethanol; Humans; Oxidative Stress; Reactive Oxygen Species | 2023 |
Chronic alcohol drinking: Liver and pancreatic cancer?
Topics: Acetaldehyde; Adaptive Immunity; Alcoholism; Carcinoma, Hepatocellular; Central Nervous System Depre | 2015 |
Review: Use of Asian samples in genetic research of alcohol use disorders: Genetic variation of alcohol metabolizing enzymes and the effects of acetaldehyde.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Asian People; Ethanol; Genetic Variation; Humans; Risk F | 2017 |
[Alcohol dehydrogenase and aldehyde dehydrogenase in malignant diseases--part I].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Causality; Comorbidity; Hum | 2008 |
Putative role of brain acetaldehyde in ethanol addiction.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Br | 2008 |
Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2 on blood acetaldehyde concentrations.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mit | 2009 |
The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, M | 2009 |
Ethanol and acetaldehyde action on central dopamine systems: mechanisms, modulation, and relationship to stress.
Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Humans; Mice; Stress, Psychological; Ventral Tegmental A | 2009 |
Alcohol and acetaldehyde in public health: from marvel to menace.
Topics: Acetaldehyde; Alcoholism; Ethanol; Humans; Oxidative Stress; Polymorphism, Genetic | 2010 |
Alcohol and aldehyde dehydrogenase polymorphisms and a new strategy for prevention and screening for cancer in the upper aerodigestive tract in East Asians.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Al | 2010 |
Acetaldehyde burst protection of ADH1B*2 against alcoholism: an additional hormesis protection against esophageal cancers following alcohol consumption?
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Animals; | 2011 |
Cellular and mitochondrial effects of alcohol consumption.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Ethanol; Female; Fetal Alcohol Spec | 2010 |
What is in that drink: the biological actions of ethanol, acetaldehyde, and salsolinol.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Central Nervous System; Ethanol; Humans; Isoqui | 2013 |
Alcohol consumption and digestive tract cancer.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; DNA; Ethanol; Gastrointestinal Neoplasms; Gastrointestin | 2012 |
Alcohol metabolism.
Topics: Absorption; Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Cytochrome P-450 CYP2E1; Electron Trans | 2012 |
Alcoholic muscle disease and biomembrane perturbations (review).
Topics: Acetaldehyde; Alcoholism; Animals; Calcium; Cell Membrane; Cholesterol; Disease Models, Animal; Etha | 2003 |
Alcohol and cancer: genetic and nutritional aspects.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Carcinogens; Cytochrome P-450 CYP2E1; DNA Methylati | 2004 |
Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Animals; Disease Models, Animal; Ethanol; Humans; | 2004 |
Alcoholic macrocytosis--is there a role for acetaldehyde and adducts?
Topics: Acetaldehyde; Alcoholism; Bone Marrow; Erythrocyte Indices; Erythrocytes; Hematologic Diseases; Hema | 2004 |
Role of diacetyl metabolite in alcohol toxicity and addiction via electron transfer and oxidative stress.
Topics: Acetaldehyde; Alcoholism; Diacetyl; Ethanol; Humans; Mutagenesis; Neoplasms; Oxidation-Reduction; Ox | 2005 |
[Biochemical basic of alcoholic liver injury].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Animals; Cytochrome P-450 CYP2E1; Ethanol; Fatty Li | 2006 |
The role of acetaldehyde in upper digestive tract cancer in alcoholics.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mit | 2007 |
Acetaldehyde adducts in circulation.
Topics: Acetaldehyde; Albumins; Alcohol Drinking; Alcoholism; Amino Acids; Autoimmunity; Biomarkers; Blood P | 2007 |
Differences in pharmacogenetics of nicotine and alcohol metabolism: review and recommendations for future research.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Cytochrome P-450 Enzyme System; Ethanol; Ethnicity | 2007 |
Brain metabolism of ethanol and alcoholism: an update.
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Catalase; Central Nervous System Depressants; Cytochrome P | 2007 |
Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Aldehyd | 2007 |
Physiology and pharmacology of alcohol: the imidazobenzodiazepine alcohol antagonist site on subtypes of GABAA receptors as an opportunity for drug development?
Topics: Acetaldehyde; Alcoholism; Animals; Azides; Behavior, Addictive; Benzodiazepines; Binding, Competitiv | 2008 |
[Excessive consumption of alcohol].
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aspartate Aminotransferases; Cholesterol; Cholesterol, H | 1982 |
Ethanol and cerebral neuroregulators.
Topics: Acetaldehyde; Acetylcholine; Alcoholism; Animals; Brain; Carbolines; Dopamine; Epinephrine; Ethanol; | 1983 |
Pharmacologic treatment of chronic alcoholism.
Topics: Acetaldehyde; Adrenergic beta-Antagonists; Alcoholics Anonymous; Alcoholism; Antidepressive Agents, | 1984 |
Clinical pathology of alcohol.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Child; Cushing Syndrome; Endocrine Glands; Enzyme | 1983 |
Metabolism and metabolic effects of alcohol.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Ethanol; Female; Humans; Liver; Mitochon | 1984 |
The role of drugs in the treatment of alcoholism.
Topics: Acetaldehyde; Alcoholism; Benzodiazepines; Cyanamide; Disulfiram; Drug Interactions; Humans; Mood Di | 1984 |
Psychiatric advances in the understanding and treatment of alcohol dependence.
Topics: Acetaldehyde; Adoption; Alcohol Oxidoreductases; Alcoholic Intoxication; Alcoholism; Antidepressive | 1984 |
Biochemical markers of a predisposition to alcoholism.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Humans; Mal | 1984 |
[Alcoholic cardiomyopathy].
Topics: Acetaldehyde; Alcoholic Beverages; Alcoholism; Beriberi; Cardiomyopathies; Echocardiography; Electro | 1982 |
[Advances in the field of alcohol-aversive agents].
Topics: Acetaldehyde; Alcohol Deterrents; Alcoholism; Cyanamide; Disulfiram; Humans; Nitroimidazoles | 1982 |
The relations of alcohol and the cardiovascular system.
Topics: Acetaldehyde; Alcoholism; Animals; Arteriosclerosis; Beriberi; Blood Pressure; Cardiomyopathy, Alcoh | 1982 |
Metabolism and metabolic effects of alcohol.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Ethanol; Humans; Hydrogen; Liver; Liver | 1980 |
Ethanol metabolism.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Catalase; Drug Interactions; Ethanol; Hu | 1980 |
Alcohol, liver injury and protein metabolism.
Topics: Acetaldehyde; Alcoholism; Amino Acids; Carbohydrate Metabolism; Collagen; Dietary Proteins; Ethanol; | 1980 |
Drug therapy: Drugs to decrease alcohol consumption.
Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Antidepressive Agents; Benzodiazepin | 1981 |
[Role of the serotoninergic structures of the brain in alcoholism].
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Brain Chemistry; Carbolines; Cricetinae; Ethanol; Humans; | 1981 |
A comparative review of the pharmacological and toxicological properties of disulfiram and calcium carbimide.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Cyanamide; Cyanides; Dis | 1981 |
The disulfiram and calcium carbimide acetaldehyde-mediated ethanol reactions.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Animals; Blood Pressure; Cyanamide; Cyanides; Di | 1981 |
Genetic implications of the alcohol-induced flushing phenomenon in Orientals.
Topics: Acetaldehyde; Alcoholism; Asian People; Cimetidine; Diphenhydramine; Ethanol; Female; Histamine; Hum | 1981 |
Adverse effects of ethanol upon sexual functioning: experimental studies in animals.
Topics: Acetaldehyde; Alcoholism; Animals; Dogs; Ethanol; Female; Gonadal Steroid Hormones; Humans; Male; Mi | 1981 |
The adverse effects of ethanol upon hypothalamic-pituitary-gonadal function in males and females compared and contrasted.
Topics: Acetaldehyde; Adult; Alcoholism; Estradiol; Ethanol; Female; Gonadotropins; Gonads; Humans; Hypothal | 1982 |
Effects of ethanol on protein synthesis and secretion.
Topics: Acetaldehyde; Alcoholism; Animals; Dose-Response Relationship, Drug; Ethanol; Humans; Liver; Liver C | 1980 |
Measuring and reporting the concentration of acetaldehyde in human breath.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Breath Tests; Ethanol; Humans; Predictive Value of | 1995 |
Alcohol and the mystique of flushing.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Alleles; Cross-Cultural Comparis | 1995 |
Enzymes and circulating proteins as markers of alcohol abuse.
Topics: Acetaldehyde; Alcoholism; Biomarkers; Clinical Enzyme Tests; gamma-Glutamyltransferase; Hemoglobins; | 1994 |
Mechanisms of ethanol-drug-nutrition interactions.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Animals; Catalase; Drug Interactions; Drug Toleranc | 1994 |
Ethanol induced cardiovascular disease.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Cardiomyopathy, Alcoholic; Cardiovascular Diseases; Coro | 1994 |
Acetate-mediated effects of ethanol.
Topics: Acetaldehyde; Acetates; Alcoholism; Animals; Brain; Dose-Response Relationship, Drug; Energy Metabol | 1994 |
Acetaldehyde adducts of proteins: diagnostic and pathogenic implications in diseases caused by excessive alcohol consumption.
Topics: Acetaldehyde; Alcoholism; Blood Proteins; Erythrocytes; Ethanol; Fibrinogen; Humans; Liver; Proteins | 1993 |
Biochemical factors in alcoholic liver disease.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Body Weight; Catalase; Ethanol; Humans; Liver; Live | 1993 |
[Alcohol and myocarditis].
Topics: Acetaldehyde; Alcoholism; Biopsy; Cardiomyopathy, Alcoholic; Electrocardiography; Endocardium; Ethan | 1996 |
[Hypertension and alcohol: central and peripheral mechanisms].
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Arousal; Brain Stem; Corticotropin-Releasing Ho | 1996 |
The separation of hemoglobin-acetaldehyde adducts by cation exchange chromatography: a brief history.
Topics: Acetaldehyde; Alcoholism; Biomarkers; Chromatography, Ion Exchange; Hemoglobins; History, 20th Centu | 1994 |
[Alcohol dependence syndrome: screening method and early detection method].
Topics: Acetaldehyde; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Ethanol; Humans; Isoenz | 1997 |
Determinations of free and bound ethanol, acetaldehyde, and acetate in human blood and urine by headspace gas chromatography.
Topics: Acetaldehyde; Acetates; Alcoholism; Biomarkers; Chromatography, Gas; Ethanol; Humans | 1998 |
Innovative technologies for the diagnosis of alcohol abuse and monitoring abstinence.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Biomarkers; Humans; Substance Abuse Detection; Transferr | 2001 |
[Laboratory diagnosis of ethyl alcohol dependence syndrome].
Topics: Acetaldehyde; Alcoholism; beta-N-Acetylhexosaminidases; Biomarkers; Humans; Liver Function Tests; Se | 2001 |
[The influence of alcohol dependence on oxidative stress parameters].
Topics: Acetaldehyde; Alcoholism; Animals; Antioxidants; Free Radicals; Humans; Lipid Peroxidation; Oxidativ | 2001 |
The role of acetaldehyde in the actions of alcohol (update 2000).
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol-Induced Disorders; Alcoholic Intoxica | 2001 |
Alcohol and cancer.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mit | 2001 |
Biochemical detection and monitoring of alcohol abuse and abstinence.
Topics: Acetaldehyde; Alanine Transaminase; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Aspartate | 2001 |
[Peripheral markers, future perspectives].
Topics: Acetaldehyde; Alcoholism; beta-N-Acetylhexosaminidases; Biomarkers; Humans; Hyaluronic Acid; Hydroxy | 2001 |
Involvement of acetaldehyde in alcohol addiction.
Topics: Acetaldehyde; Alcoholism; Animals; Humans | 2002 |
[Alcohol and oropharyngolaryngeal and digestive tract cancer].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholic Beverages; Alcoholism; Aldehyde Dehydrogenase; Aldehy | 2001 |
Pharmacological aspects of physical dependence on ethanol.
Topics: Acetaldehyde; Adenosine Triphosphatases; Alcoholism; Animals; Behavior, Animal; Disease Models, Anim | 1976 |
Mutagenic, cancerogenic and teratogenic effects of alcohol.
Topics: Acetaldehyde; Adult; Alcoholism; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; Drosophi | 1979 |
Metabolic pathways of alcohol in the liver.
Topics: Acetaldehyde; Acetates; Alcohol Oxidoreductases; Alcoholism; Animals; Bile Acids and Salts; Catalase | 1976 |
[Biochemical basis of the effects of alcohol].
Topics: Acetaldehyde; Alcoholism; Arrhythmias, Cardiac; Carbohydrate Metabolism; Citrates; Citric Acid Cycle | 1976 |
The metabolism of biogenic amines in experimental animals and in human subjects during acute and chronic administration of ethanol.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Aldehyde Oxidoreductases; Animals; Biogenic Amines | 1977 |
Differences in hepatic and metabolic changes after acute and chronic alcohol consumption.
Topics: Acetaldehyde; Acetates; Acute Disease; Alcohol Oxidoreductases; Alcoholism; Animals; Catalase; Chron | 1975 |
The disulfiram--ethanol reaction: a review.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Disulfiram; Dopamine beta-Hydroxylase; Enzyme I | 1977 |
Drug therapy reviews: management of the disulfiram-alcohol reaction.
Topics: Acetaldehyde; Alcoholism; Antidotes; Disulfiram; Drug Interactions; Ethanol; Humans | 1977 |
Immunologic reactivity and alcoholic liver disease.
Topics: Acetaldehyde; Alcoholism; Antigen-Antibody Reactions; B-Lymphocytes; Caffeine; Chemical and Drug Ind | 1975 |
[Interaction of acetaldehyde and proteins].
Topics: Acetaldehyde; Alcoholism; Animals; Blood Proteins; Humans; In Vitro Techniques; Liver; Protein Bindi | 1992 |
[Biological markers of alcoholism].
Topics: Acetaldehyde; Alcoholism; Asialoglycoproteins; Autoantibodies; beta-N-Acetylhexosaminidases; Biomark | 1992 |
Medicobiological and genetic studies on alcoholism. Role of metabolic variation and ethnicity on drinking habits, alcohol abuse and alcohol-related mortality.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Central Nervous System; Diseases in Twins; Ethanol; Feta | 1992 |
A review of the pharmacokinetics and pharmacodynamics of disulfiram and its metabolites.
Topics: Acetaldehyde; Alcoholism; Disulfiram; Humans | 1992 |
The pharmacology and toxicology of disulfiram and its metabolites.
Topics: Acetaldehyde; Alcoholism; Animals; Disulfiram; Humans | 1992 |
[Pathogenesis of alcoholic liver disease].
Topics: Acetaldehyde; Alcoholism; Environment; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Nutritiona | 1992 |
Alcohol, liver, and nutrition.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Collagen; Ethanol; Hormones; Humans; Liver; Liver C | 1991 |
Contribution of exogenous ethanol and endogenous substrates to acetaldehyde-adduct formation in liver injury.
Topics: Acetaldehyde; Alcoholism; Animals; Carbon Tetrachloride Poisoning; Erythrocytes; Ethanol; Humans; Li | 1991 |
The chemistry of acetaldehyde-protein adducts.
Topics: Acetaldehyde; Alcoholism; Animals; Humans; Kinetics; Protein Binding; Proteins; Schiff Bases; Serum | 1991 |
Biochemical mechanisms of alcohol-induced hepatic injury.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Animals; Drug Tolerance; Ethanol; Humans; Liver; Li | 1991 |
The genesis of alcoholic brain tissue injury.
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Brain Damage, Chronic; Ethanol; Free Radicals; Humans; Liv | 1990 |
Alcohol and aldehydes.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Carcinogens; Ethanol; Humans; Mutagens | 1990 |
Alcohol challenge with sons of alcoholics: a critical review and analysis.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Arousal; Child of Impaired Parents; Ethanol; Humans; Mal | 1990 |
Alcohol and the liver: metabolism of ethanol, metabolic effects and pathogenesis of injury.
Topics: Acetaldehyde; Acetates; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Blood G | 1985 |
[Biochemical aspects of alcoholism. IV. Alcohol-induced diseases of the liver].
Topics: Acetaldehyde; Alcoholism; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Humans; Liver; Live | 1989 |
Laboratory markers of alcoholism.
Topics: Acetaldehyde; Alcoholism; Asialoglycoproteins; Aspartate Aminotransferases; Clinical Enzyme Tests; E | 1989 |
Oxygen radicals from acetaldehyde.
Topics: Acetaldehyde; Alcoholism; Animals; Free Radicals; Humans; Oxygen; Superoxide Dismutase | 1989 |
[Role of the catecholaminergic system of the brain in addiction to alcohol (review)].
Topics: Acetaldehyde; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcohol Deterrents; Alcohol | 1985 |
Racial differences in alcohol sensitivity.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholism; Aldehyde | 1986 |
Ethanol metabolism by the liver.
Topics: Acetaldehyde; Adenosine Triphosphate; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Al | 1985 |
Modulation of ethanol intake by serotonin uptake inhibitors.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Brain; Citalopram; Disulfiram; Dopamine; Humans | 1986 |
Alcohol and nutrition: caloric value, bioenergetics, and relationship to liver damage.
Topics: Acetaldehyde; Adenosine Triphosphate; Adolescent; Adult; Aged; Alcohol Dehydrogenase; Alcohol Drinki | 1986 |
Metabolism of ethanol and its consequences for the liver and gastrointestinal tract.
Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Gastrointestinal Diseases; Humans; Liver Diseases, Alcoh | 1988 |
Role of acetaldehyde in the pathogenesis of alcoholic liver disease.
Topics: Acetaldehyde; Alcoholism; Free Radicals; Humans; Liver Diseases, Alcoholic | 1988 |
Role of acetaldehyde in the pathogenesis of alcoholic liver disease.
Topics: Acetaldehyde; Alcoholism; Humans; Liver; Liver Diseases, Alcoholic | 1988 |
Acetaldehyde and its condensation products as markers in alcoholism.
Topics: Acetaldehyde; Alcoholism; Ethanol; Humans; Inactivation, Metabolic | 1988 |
[Pathogenesis of the fetal alcohol syndrome].
Topics: Acetaldehyde; Alcoholism; Female; Fetal Alcohol Spectrum Disorders; Humans; Placenta; Pregnancy; Pre | 1988 |
The role of genetics in the pathogenesis of alcoholism.
Topics: Acetaldehyde; Adoption; Adult; Alcoholism; Diseases in Twins; Electroencephalography; Environment; F | 1988 |
[New biological indicators of alcoholism].
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Apolipoproteins A; Aspartate Aminotransferases; Er | 1987 |
Genetic variability of enzymes of alcohol metabolism in human beings.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Ethanol; Humans; Kinetics; Liver; Polymorphism, G | 1986 |
Studies of populations at high risk for alcoholism.
Topics: Acetaldehyde; Adoption; Alcoholism; Attention Deficit Disorder with Hyperactivity; Cognition; Diseas | 1985 |
Alcohol and alcohol problems research 2. Japan.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Female; Fetal Alcohol Spectrum D | 1985 |
Clinical implications of acetaldehyde adducts with hemoglobin.
Topics: Acetaldehyde; Alcoholism; Amino Acids; Diabetes Mellitus; Dialysis; Glycated Hemoglobin; Hemoglobin | 1985 |
Multiple metabolite theory, alcohol drinking and the alcogene.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Brain; Carbolines; Dopamine; Ethanol; Genes; Hu | 1985 |
Structural & biological studies of the acetaldehyde adducts of enkephalins and related peptides: a short review.
Topics: Acetaldehyde; Alcoholism; Animals; Binding Sites; Enkephalin, Leucine; Enkephalin, Methionine; Enkep | 1985 |
[Interaction of alcohol with the liver, nutrition, drugs and carcinogens].
Topics: Acetaldehyde; Alcoholism; Animals; Carcinogens; Disease Models, Animal; Ethanol; Humans; Liver; Live | 1985 |
Ethanol metabolism and uric acid.
Topics: Acetaldehyde; Alcoholism; Ethanol; Fasting; Gout; Humans; Hyperlipidemias; Ketone Bodies; Lactates; | 1972 |
Metabolic aspects of alcohol and their biological significance.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Bone and Bones; Cardiomyopathies; Catala | 1973 |
Metabolic effects produced by alcohol in the liver and other tissues.
Topics: Acetaldehyde; Acetates; Alcoholism; Coenzymes; Deficiency Diseases; Dietary Carbohydrates; Enzymes; | 1968 |
Speculations on the biochemical pharmacology of ethanol.
Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Humans | 1974 |
Biologic concomitants of alcoholism. 1.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholic Intoxication; Alcoholism; Animals; Blood Glucose; C | 1970 |
[Further facts about the effects of disulfiram].
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Disulfiram; Drug Tolerance; Humans; Oxyg | 1970 |
7 trials available for acetaldehyde and Alcohol Abuse
| Article | Year |
|---|---|
Pharmacokinetic and pharmacodynamic basis for partial protection against alcoholism in Asians, heterozygous for the variant ALDH2*2 gene allele.
Topics: Acetaldehyde; Acetates; Administration, Oral; Adult; Alcoholism; Aldehyde Dehydrogenase; Aldehyde De | 2007 |
A placebo-controlled double-blind comparative clinical study of the disulfiram- and calcium carbimide-acetaldehyde mediated ethanol reactions in social drinkers.
Topics: Acetaldehyde; Adult; Alcoholism; Clinical Trials as Topic; Cyanamide; Cyanides; Disulfiram; Double-B | 1983 |
Disulfiram treatment increases plasma and red blood cell acetaldehyde in abstinent alcoholics.
Topics: Acetaldehyde; Adult; Alcohol Deterrents; Alcoholism; Analysis of Variance; Disulfiram; Erythrocytes; | 2000 |
Patient management in disulfiram implant therapy.
Topics: Acetaldehyde; Administration, Oral; Alcohol Drinking; Alcoholism; Disulfiram; Drug Implants; Humans; | 1979 |
Disulfiram implant: a double-blind placebo controlled follow-up on treatment outcome.
Topics: Acetaldehyde; Adult; Aged; Alcohol Drinking; Alcoholism; Disulfiram; Double-Blind Method; Drug Impla | 1991 |
[Cardiovascular and metabolic changes in the antabuse-alcohol reaction: basis for the diagnosis of degree of severity].
Topics: Acetaldehyde; Adult; Alcoholism; Clinical Trials as Topic; Disulfiram; Drug Evaluation; Drug Synergi | 1987 |
Acetaldehyde concentrations in alveolar air following a standard dose of ethanol in man.
Topics: Acetaldehyde; Acetone; Adult; Air; Alcoholism; Blood Chemical Analysis; Body Weight; Brain Damage, C | 1965 |
374 other studies available for acetaldehyde and Alcohol Abuse
| Article | Year |
|---|---|
Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease.
Topics: Acetaldehyde; Adult; Alcoholism; Biomarkers; Fatty Liver; Humans; Immunoglobulin A; Immunoglobulin G | 2022 |
Signatures of Convergent Evolution and Natural Selection at the Alcohol Dehydrogenase Gene Region are Correlated with Agriculture in Ethnically Diverse Africans.
Topics: Acetaldehyde; Agriculture; Alcohol Dehydrogenase; Alcoholism; Ethanol; Ethiopia; Humans; Nucleotides | 2022 |
Malondialdehyde acetaldehyde adduction of surfactant protein D attenuates SARS-CoV-2 spike protein binding and virus neutralization.
Topics: Acetaldehyde; Alcoholism; COVID-19; Ethanol; Humans; Malondialdehyde; Pandemics; Protein Binding; Pr | 2023 |
Blood Cell Responses Following Heavy Alcohol Consumption Coincide with Changes in Acute Phase Reactants of Inflammation, Indices of Hemolysis and Immune Responses to Ethanol Metabolites.
Topics: Acetaldehyde; Acute-Phase Proteins; Adult; Alcohol Drinking; Alcoholism; Bilirubin; Biomarkers; Bloo | 2022 |
Association of ADH1B rs1229984, ADH1C rs698, and ALDH2 rs671 with Alcohol abuse and Alcoholic Cirrhosis in People Living in Northeast Vietnam.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde | 2023 |
Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking.
Topics: Acetaldehyde; Alanine Transaminase; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase, Mitochondr | 2019 |
Recognition of a disulfiram ethanol reaction in the emergency department is not always straightforward.
Topics: Acetaldehyde; Adult; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Disulfiram; Drug Interactions | 2020 |
Malondialdehyde-Acetaldehyde Adduct Formation Decreases Immunoglobulin A Transport across Airway Epithelium in Smokers Who Abuse Alcohol.
Topics: Acetaldehyde; Alcoholism; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Epithelial | 2021 |
Acetaldehyde exposure underlies functional defects in monocytes induced by excessive alcohol consumption.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase, Mitochond | 2021 |
Integration of a physiologically-based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for characterization of ethanol and acetaldehyde metabolism.
Topics: Acetaldehyde; Acetaldehyde Dehydrogenase Inhibitors; Alcohol Deterrents; Alcoholism; Aldehyde Dehydr | 2021 |
AAV Gene Therapy for Alcoholism: Inhibition of Mitochondrial Aldehyde Dehydrogenase Enzyme Expression in Hepatoma Cells.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase, Mitochondrial; Asian People; Car | 2017 |
Malondialdehyde-Acetaldehyde (MAA) Protein Adducts Are Found Exclusively in the Lungs of Smokers with Alcohol Use Disorders and Are Associated with Systemic Anti-MAA Antibodies.
Topics: Acetaldehyde; Adult; Alcoholism; Autoantibodies; Female; Humans; Lung; Male; Malondialdehyde; Protei | 2017 |
Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde.
Topics: Acetaldehyde; Aged; Aging, Premature; Alcoholism; Aldehyde Dehydrogenase, Mitochondrial; Ethanol; Hu | 2019 |
The influence of B-complex vitamins upon the prolongation of prothrombin time by acetaldehyde.
Topics: Acetaldehyde; Alcoholism; Amines; Anticoagulants; Ethanol; Humans; NAD; Niacinamide; Prothrombin Tim | 2013 |
Efficacy of D-penicillamine, a sequestering acetaldehyde agent, in the prevention of alcohol relapse-like drinking in rats.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Brain; Chelating Agents; Dose-Response Relation | 2013 |
Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population.
Topics: Acetaldehyde; Adolescent; Alcoholism; Anxiety; Case-Control Studies; Cohort Studies; Comorbidity; Fe | 2014 |
Long-term inhibition of ethanol intake by the administration of an aldehyde dehydrogenase-2 (ALDH2)-coding lentiviral vector into the ventral tegmental area of rats.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochon | 2015 |
Aldehyde dedydrogenase-2 plays a beneficial role in ameliorating chronic alcohol-induced hepatic steatosis and inflammation through regulation of autophagy.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Au | 2015 |
Acetaldehyde production capacity of salivary microflora in alcoholics during early recovery.
Topics: Acetaldehyde; Adult; Alcohol Abstinence; Alcoholism; Beer; Biomarkers; Chromatography, Gas; Craving; | 2015 |
The total margin of exposure of ethanol and acetaldehyde for heavy drinkers consuming cider or vodka.
Topics: Acetaldehyde; Adult; Alcoholic Beverages; Alcoholism; Algorithms; Ethanol; Female; Fermentation; Foo | 2015 |
Opioid antagonists block acetaldehyde-induced increments in dopamine neurons activity.
Topics: Acetaldehyde; Alcoholism; Animals; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; | 2016 |
Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer.
Topics: Acetaldehyde; Adolescent; Adult; Aged; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase, Mi | 2016 |
Quantification of Neural Ethanol and Acetaldehyde Using Headspace GC-MS.
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Brain Chemistry; Ethanol; Female; Gas Chromatography-Mass | 2016 |
Mitochondrial remodeling in the liver following chronic alcohol feeding to rats.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Energy Metabolism; Ethanol; Humans; Malates; Mi | 2017 |
Alcohol in Mayan Guatemala: consumption, distribution, production and composition of cuxa.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholic Beverages; Alcoholic Intoxication; Alcoholism; Cult | 2009 |
Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Ca | 2009 |
Measurement of free and bound alcohol metabolites and methanol in human biological samples--free and bound alcohol metabolites and methanol in acute alcohol administration.
Topics: Acetaldehyde; Acetates; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Chromatography, Gas; Ethano | 2009 |
Use of acetaldehyde and methanol as markers of alcohol abuse and their measurement.
Topics: Acetaldehyde; Acetates; Adult; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde D | 2009 |
A new CE-ESI-MS method for the detection of stable hemoglobin acetaldehyde adducts, potential biomarkers of alcohol abuse.
Topics: Acetaldehyde; Alcoholism; Biomarkers; Electrophoresis, Capillary; Hemoglobins; Humans; Spectrometry, | 2009 |
Local salsolinol modulates dopamine extracellular levels from rat nucleus accumbens: shell/core differences.
Topics: Acetaldehyde; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Chromatography, High P | 2009 |
Association between quality of cheap and unrecorded alcohol products and public health consequences in Poland.
Topics: Acetaldehyde; Alcoholic Beverages; Alcoholism; Alcohols; Anions; Central Nervous System Depressants; | 2009 |
Pharmacokinetic and pharmacodynamic basis for overcoming acetaldehyde-induced adverse reaction in Asian alcoholics, heterozygous for the variant ALDH2*2 gene allele.
Topics: Acetaldehyde; Adult; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Alle | 2009 |
Mechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model.
Topics: Acetaldehyde; Adenoviridae; Alcohol Dehydrogenase; Alcoholism; Alleles; Amino Acid Substitution; Ani | 2010 |
Genetic determinants of both ethanol and acetaldehyde metabolism influence alcohol hypersensitivity and drinking behaviour among Scandinavians.
Topics: Acetaldehyde; Adolescent; Adult; Aged; Alcoholic Beverages; Alcoholism; Aldehyde Dehydrogenase; Alde | 2010 |
[Tobacco smoking by patients treat for alcohol addiction--interaction of psychoactive substances].
Topics: Acetaldehyde; Acetone; Adult; Alcoholism; Cotinine; Drug Interactions; Female; Humans; Male; Methano | 2009 |
Polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 and the blood and salivary ethanol and acetaldehyde concentrations of Japanese alcoholic men.
Topics: Acetaldehyde; Adult; Aged; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehyd | 2010 |
Application of LC-TOF MS to analysis of hemoglobin acetaldehyde adducts in alcohol detoxification patients.
Topics: Acetaldehyde; Adult; Aged; Alcoholism; Amino Acid Sequence; Child; Child, Preschool; Chromatography, | 2010 |
Using a pharmacokinetic model to relate an individual's susceptibility to alcohol dependence to genotypes.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Alcoholism; Alcohols; Aldehyde Dehydrogenase; | 2010 |
[A serious "acetaldehyde syndrome" compounded by dopamine].
Topics: Acetaldehyde; Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Anti-Anxiety Agents; Antidepre | 2011 |
Alcohol consumption and cancer risk: revisiting guidelines for sensible drinking.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Central Nervous System Depressants; Dose-Response Relati | 2011 |
Reward and relapse: complete gene-induced dissociation in an animal model of alcohol dependence.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Catalase; Cues; Disease Models, Animal; Ethanol | 2012 |
Analysis of N(ε) -ethyllysine in human plasma proteins by gas chromatography-negative ion chemical ionization/mass spectrometry as a biomarker for exposure to acetaldehyde and alcohol.
Topics: Acetaldehyde; Adult; Aged; Alcoholism; Biomarkers; Carbon Isotopes; Case-Control Studies; Central Ne | 2012 |
Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde-derived DNA damage in the blood of Japanese alcoholics.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogena | 2012 |
ADH and ALDH polymorphisms and alcohol dependence in Mexican and Native Americans.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogena | 2012 |
Genes encoding enzymes involved in ethanol metabolism.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Humans | 2012 |
[Measurement of anti-acetaldehyde protein adduct IgA, IgG, IgM antibody titers in the sera of human alcoholics].
Topics: Acetaldehyde; Alcoholics; Alcoholism; Antibodies, Anti-Idiotypic; Humans; Immunoglobulin A; Immunogl | 2002 |
Neurotoxicity of acetaldehyde-derived advanced glycation end products for cultured cortical neurons.
Topics: Acetaldehyde; Albumins; Alcoholism; Animals; Antibodies; Apoptosis; Cattle; Cells, Cultured; Cerebra | 2003 |
Sugar, pyruvate and acetaldehyde levels in the blood of alcohol addicts after ingestion of dextrose.
Topics: Acetaldehyde; Alcoholism; Blood; Blood Glucose; Catabolite Repression; Eating; Ethanol; Glucose; Hum | 1953 |
[Complications of various types of acetaldehyde poisoning in treatment of chronic alcoholism].
Topics: Acetaldehyde; Alcoholism; Disulfiram; Ethanol; Humans; Poisoning | 1954 |
Acetaldehyde adducts in the brain of alcoholics.
Topics: Acetaldehyde; Alcoholism; Brain; Brain Chemistry; Ethanol; Fatal Outcome; Humans; Immunohistochemist | 2003 |
Women and alcohol susceptibility: could differences in alcohol metabolism predispose women to alcohol-related diseases?
Topics: Acetaldehyde; Adult; Alcoholism; Ethanol; Female; Gene Frequency; Genetic Predisposition to Disease; | 2003 |
Brain mitochondrial aldehyde dehydrogenase: relation to acetaldehyde aversion in low-alcohol-drinking (UChA) and high-alcohol-drinking (UChB) rats.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochon | 2003 |
Effects of ascorbic acid in antabuse-alcohol reactions.
Topics: Acetaldehyde; Alcoholism; Ascorbic Acid; Biochemical Phenomena; Disulfiram; Ethanol; Humans; Vitamin | 1951 |
Assessment of association between mitochondrial aldehyde dehydrogenase polymorphism and Alzheimer's disease in an older Korean population.
Topics: Acetaldehyde; Age Factors; Aged; Aging; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehy | 2004 |
Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Ethanol; Female; Gene Frequency; Genotype; Humans; | 2004 |
Prolonged central sensory conduction time in alcoholics with hypoactive aldehyde dehydrogenase-2.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Evoked Pote | 2004 |
Site of the formation of acetaldehyde after ingestion of antabuse (tetraethylthiuramdisulphide) and alcohol.
Topics: Acetaldehyde; Alcoholism; Disulfiram; Eating; Ethanol; Humans | 1949 |
The rate of acetaldehyde metabolism in rabbits treated with antabuse (tetraethylthiuramdisulphide).
Topics: Acetaldehyde; Alcoholism; Animals; Biochemical Phenomena; Disulfiram; Lagomorpha; Rabbits | 1949 |
The rate of acetaldehyde metabolism in isolated livers and hind limbs of rabbits treated with antabuse (tetraethylthiuramdisulphide).
Topics: Acetaldehyde; Alcoholism; Animals; Disulfiram; Hindlimb; Lagomorpha; Liver; Lower Extremity; Rabbits | 1949 |
[Treatment of alcoholism with antabuse (tetraethylthiuram disulfide); importance of acetaldehyde].
Topics: Acetaldehyde; Alcoholism; Disulfiram | 1950 |
[Treatment of alcoholism with antabuse (tetraethylthiuran disulfide); importance of the acetaldehyde].
Topics: Acetaldehyde; Alcoholism; Disulfides; Disulfiram | 1950 |
[Acetaldehyde concentration in acute ethanol-intoxicated patients addicted to alcohol].
Topics: Acetaldehyde; Adult; Alcoholic Intoxication; Alcoholism; Biomarkers; Ethanol; Humans; Male; Middle A | 2004 |
Mechanisms of alcohol-associated cancers: introduction and summary of the symposium.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Carcinogens; Cytochrome P-450 CYP2E1; Ethanol; Humans; N | 2005 |
Recent advances in alcohol-induced adduct formation.
Topics: Acetaldehyde; Alcohol-Related Disorders; Alcoholism; Animals; Cardiomyopathy, Alcoholic; DNA Adducts | 2005 |
From alcohol toxicity to treatment.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol-Related Disorders; Alcoholism; Alleles; Cholestasis, In | 2005 |
Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college students.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcohol Drinking; Alcoholism; Alleles; Female; Genetic P | 2005 |
Aldehyde dehydrogenase (ALDH2) activity in hepatoma cells is reduced by an adenoviral vector coding for an ALDH2 antisense mRNA.
Topics: Acetaldehyde; Adenoviridae; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondria | 2005 |
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats.
Topics: Acamprosate; Acetaldehyde; Alcohol Deterrents; Alcoholism; Animals; Disease Models, Animal; Ethanol; | 2005 |
Cytotoxicity of acetaldehyde-derived advanced glycation end-products (AA-AGE) in alcoholic-induced neuronal degeneration.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies; Cells, Cultured; Central Nervous System Depressants; | 2005 |
Genetic associations of alcohol and aldehyde dehydrogenase with alcohol dependence and their mechanisms of action.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Genetic Linkage; H | 2005 |
Erythrocyte and plasma protein modification in alcoholism: a possible role of acetaldehyde.
Topics: Acetaldehyde; Adult; Alcoholism; Alcohols; Blood Proteins; Electrophoresis, Polyacrylamide Gel; Eryt | 2006 |
Acetaldehyde involvement in positive and negative alcohol expectancies in han Chinese persons with alcoholism.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, M | 2006 |
IgAs against acetaldehyde-modified red cell protein as a marker of ethanol consumption in male alcoholic subjects, moderate drinkers, and abstainers.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Central Nervous System Depressants; C | 2006 |
Increased DNA damage in ALDH2-deficient alcoholics.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochon | 2006 |
The effect of acetaldehyde on human plasma factor XIII function.
Topics: Acetaldehyde; Alcoholism; Blood Coagulation; Factor XIII; Factor XIIIa; Fibrinogen; Humans; Thrombin | 2007 |
Contribution of the alcohol dehydrogenase-1B genotype and oral microorganisms to high salivary acetaldehyde concentrations in Japanese alcoholic men.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Ethanol; Humans; Japan; Mouth; Saliva | 2007 |
Acetaldehyde, polymorphisms and the cardiovascular system.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mit | 2007 |
[Evaluation of ventilation disorders in alcohol addicted males].
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Bi | 2007 |
Herbal mixtures consisting of puerarin and either polyenylphosphatidylcholine or curcumin provide comprehensive protection against alcohol-related disorders in P rats receiving free choice water and 15% ethanol in pure water.
Topics: Acetaldehyde; Alcohol-Related Disorders; Alcoholism; Animals; Apoptosis; Curcumin; Electroencephalog | 2007 |
Effect of acetaldehyde upon cathepsin G and chymase. NRAS implications.
Topics: Acetaldehyde; Alcoholism; Animals; Cathepsin G; Cathepsins; Chymases; Hypertension; Rats; Renin-Angi | 2008 |
Key role of ethanol-derived acetaldehyde in the motivational properties induced by intragastric ethanol: a conditioned place preference study in the rat.
Topics: Acetaldehyde; Alcoholism; Animals; Association Learning; Choice Behavior; Dose-Response Relationship | 2008 |
Demonstration of ethanol-induced protein adducts in oral leukoplakia (pre-cancer) and cancer.
Topics: Acetaldehyde; Alcoholism; Aldehydes; Carcinoma, Squamous Cell; Cytochrome P-450 CYP2E1; Ethanol; Fem | 2008 |
Tolerance to disulfiram induced by chronic alcohol intake in the rat.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Cyan | 2008 |
Sudden death durin disulfiram--alcohol reaction.
Topics: Acetaldehyde; Adult; Alcoholism; Death, Sudden; Disulfiram; Electrocardiography; Humans; Male; Myoca | 1967 |
Occurrence of trace indoles in mammals.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Animals; Brain; Carbolines; Formaldehyde; Humans; | 1984 |
Selectively reduced hepatic acetaldehyde dehydrogenase in alcoholics.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Cytosol; Humans; Liver; Mitochondria, Liver | 1980 |
Acetaldehyde and the alcoholic.
Topics: Acetaldehyde; Alcoholism; Breath Tests; Humans | 1980 |
Is role of acetaldehyde in alcoholism based on an analytical artifact?
Topics: Acetaldehyde; Alcoholism; Chromatography, Gas; Ethanol; Humans | 1981 |
Acetaldehyde in alcoholism.
Topics: Acetaldehyde; Adult; Alcoholism; Humans; Hydroxytryptophol; Male | 1982 |
Aldehyde dehydrogenase and alcoholism.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Cytosol; Humans; Liver; Liver Diseases, Alcoholi | 1983 |
Fetal abnormality and maternal ethanol metabolism.
Topics: Acetaldehyde; Alcoholism; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Maternal-Fetal | 1983 |
Effect of alcohol consumption on hepatic aldehyde dehydrogenase activity in alcoholic patients.
Topics: Acetaldehyde; Adult; Aged; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreduc | 1984 |
Alcohol addiction: are the endogenous opioids involved?
Topics: Acetaldehyde; Alcoholism; Animals; Endorphins; Enkephalins; Humans; Isoquinolines; Mice; Naloxone; R | 1981 |
Behavioral and physiological effects of ethanol in high-risk and control children: a pilot study.
Topics: Acetaldehyde; Adolescent; Affect; Alcohol Drinking; Alcoholism; beta-Endorphin; Child; Child Behavio | 1983 |
Metabolic and nutritional aspects of the effects of ethanol.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Aldehyde Oxidoreductases; Animals; Deficiency Dis | 1983 |
Human blood acetaldehyde levels: with improved methods, a clearer picture emerges.
Topics: Acetaldehyde; Alcoholism; Asian People; Blood Chemical Analysis; Humans; White People | 1983 |
Determinants of blood acetaldehyde level during ethanol oxidation in chronic alcoholics.
Topics: Acetaldehyde; Adult; Alcohol Oxidoreductases; Alcoholism; Aldehyde Oxidoreductases; Ethanol; Fructos | 1983 |
The polymorphisms of alcohol and aldehyde dehydrogenase and their significance for acetaldehyde toxicity.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Aldehyde Dehydrogenase; Al | 1983 |
Alcohol sensitivity related to polymorphism of alcohol-metabolizing enzymes in Japanese.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholic Intoxication; Alcohol | 1983 |
Pharmacogenetics of alcohol sensitivity.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Aldehyde Dehydrogenase; Al | 1983 |
Biology of disease. Alcoholism and aldehydism: new biomedical concepts.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Aldehyde Dehydrogenase; Al | 1984 |
Lipid peroxidation in alcoholic myopathy and cardiomyopathy.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Cardiomyopathy, Alcoholic; Catalase; Eth | 1984 |
Alcohol-induced liver injury. The role of oxygen.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Humans; L-Lactate | 1984 |
Acetaldehyde and aldehyde dehydrogenases--central problems in the study of alcoholism.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Ethanol; Humans | 1983 |
Microsomal ethanol oxidizing system (MEOS): interaction with ethanol, drugs and carcinogens.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Carcinogens; Cata | 1983 |
Blood acetaldehyde concentration gradient between hepatic and antecubital venous blood in ethanol-intoxicated alcoholics and controls.
Topics: Acetaldehyde; Adult; Alcoholic Intoxication; Alcoholism; Ethanol; Humans; Kinetics; Lactates; Lactic | 1984 |
Sudden death during disulfiram-ethanol reaction.
Topics: Acetaldehyde; Adult; Alcoholism; Death, Sudden; Disulfiram; Humans; Male | 1984 |
Selective fetal malnutrition: the effect of nicotine, ethanol, and acetaldehyde upon in vitro uptake of alpha-aminoisobutyric acid by human term placental villous slices.
Topics: Acetaldehyde; Alcoholism; Aminoisobutyric Acids; Biological Transport, Active; Chorionic Villi; Etha | 1984 |
The effect of acetaldehyde concentrations on the relative rates of formation of acetaldehyde-modified hemoglobins.
Topics: Acetaldehyde; Adult; Alcoholism; Chromatography, High Pressure Liquid; Diabetes Mellitus; Glycated H | 1984 |
Effect of ethanol and acetaldehyde on gamma-hydroxybutyric acid in rat brain and liver.
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Ethanol; Humans; Hydroxybutyrates; Liver; Male; Pyrazoles; | 1984 |
Aldehyde oxidizing capacity of erythrocytes in normal and alcoholic individuals.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; | 1983 |
Blood ethanol and acetaldehyde levels in Japanese alcoholics and controls.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; | 1983 |
Human blood acetaldehyde concentration during ethanol oxidation (update 1982).
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; | 1983 |
The gastro-intestinal metabolism of ethanol in the rat. Effect of chronic alcoholic intoxication.
Topics: Acetaldehyde; Acetates; Alcoholism; Animals; Ethanol; Gastric Mucosa; Humans; Intestinal Mucosa; Mal | 1983 |
Alcohol oxidation by isozyme 3a of liver microsomal cytochrome P-450.
Topics: Acetaldehyde; Alcoholism; Aniline Compounds; Animals; Cytochrome P-450 Enzyme System; Ethanol; Human | 1983 |
Effects of chronic ethanol feeding and acetaldehyde metabolism on calcium transport by rat liver mitochondria.
Topics: Acetaldehyde; Alcoholism; Animals; Biological Transport, Active; Calcium; Ethanol; Humans; Kinetics; | 1983 |
Acetaldehyde-hemoglobin adducts: an unreliable marker of alcohol abuse.
Topics: Acetaldehyde; Adult; Alcoholism; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electr | 1984 |
Effect of ethanol on hepatic secretory proteins.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Animals; Blood Proteins; Ethanol; Glycoproteins; H | 1984 |
Inhibition of placental amino acid uptake in rats following acute and chronic ethanol exposure.
Topics: Acetaldehyde; Alanine; Alcoholism; Amino Acids; Aminoisobutyric Acids; Animals; Betaine; Cycloleucin | 1982 |
Alcoholic cardiomyopathy--acetaldehyde poisoning rat: myocardial and serum enzyme changes in acute exposure.
Topics: Acetaldehyde; Alcoholism; Animals; Aspartate Aminotransferases; Cardiomyopathies; Creatine Kinase; H | 1983 |
Genetics and alcohol: implications for human disease.
Topics: Acetaldehyde; Adolescent; Adult; Alcohol Drinking; Alcoholism; Female; Humans; Male; Middle Aged; Pe | 1981 |
Alcohol metabolism and alcoholism--pharmacogenetic considerations.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Ethanol; Ethnicity; Fructose; Humans; Liver; NAD; | 1980 |
Acetaldehyde: its role in alcoholic toxicity and dependence.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Cardiovascular System; Central Nervous System; Hu | 1981 |
Cutaneous reactions to lower aliphatic alcohols before and during disulfiram therapy.
Topics: 1-Propanol; Acetaldehyde; Alcoholism; Disulfiram; Drug Interactions; Erythema; Ethanol; Female; Huma | 1982 |
Alcoholism: polygenic influence on a multifactorial disorder.
Topics: Acetaldehyde; Adoption; Alcoholism; Diseases in Twins; Ethanol; Family Characteristics; Female; Gene | 1982 |
Impaired acetaldehyde oxidation in alcoholics.
Topics: Acetaldehyde; Adult; Alcoholism; Aldehyde Oxidoreductases; Ethanol; Humans; Lactates; Lactic Acid; L | 1982 |
Alcohol-related flushing and the risk for alcoholism in sons of alcoholics.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Ethanol; Face; Heart Rate; Humans; Hyperemia; Mal | 1982 |
Medical disorders of alcoholism. Pathogenesis and treatment.
Topics: Acetaldehyde; Acetates; Alcoholism; Amino Acids; Animals; Arteriosclerosis; Blood; Brain; Digestion; | 1982 |
[Catecholamine metabolism and alcohol].
Topics: Acetaldehyde; Alcoholism; Brain; Catecholamines; Ethanol; Humans; Isoquinolines | 1982 |
Development of histaminergic pathways in brain as influenced by maternal alcoholism.
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Brain Chemistry; Female; Histamine; Histidine Decarboxylas | 1980 |
Chronic ethanol consumption and exocrine pancreatic response to ethanol and acetaldehyde in the rat.
Topics: Acetaldehyde; Alcoholism; Animals; Disease Models, Animal; Ethanol; Humans; Pancreas; Rats | 1980 |
Acetaldehyde acutely impairs canine testicular testosterone secretion.
Topics: Acetaldehyde; Alcoholism; Animals; Chorionic Gonadotropin; Disease Models, Animal; Dogs; Ethanol; Hu | 1981 |
Determinants of plasma free acetaldehyde levels during the oxidation of ethanol: effects of chronic ethanol feeding.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Ethanol; Humans | 1981 |
Influence of chronic ethanol uptake and acute acetaldehyde treatment on the chromosomes of bone-marrow cells and peripheral lymphocytes of Chinese hamsters.
Topics: Acetaldehyde; Alcoholism; Animals; Bone Marrow; Chromosome Aberrations; Chromosomes; Cricetinae; Cri | 1981 |
Alcohol embryopathy: some facts and speculations about pathogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcoholic Beverages; Alcoholism; Brain; Child; Child, Pre | 1981 |
[Effect of alcohol on serum thyrotropin concentration of rats predisposed and unpredisposed to alcohol].
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Cold Temperature; Disease Susceptibility; Dopamine; Female | 1981 |
Absence of a role for salsolinol in the mechanism of ethanol teratogenicity.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcoholism; Animals; Animals, Newborn; Ethanol; Female; F | 1981 |
An examination of the role of TIQ alkaloids in alcohol intake: reinforcers, satiety agents or artifacts.
Topics: Acetaldehyde; Alcoholism; Alkaloids; Animals; Body Weight; Disease Models, Animal; Ethanol; Humans; | 1982 |
[Fetal alcohol syndrome].
Topics: Acetaldehyde; Adult; Alcoholism; Chromatography, Gas; Ethanol; Female; Fetal Alcohol Spectrum Disord | 1981 |
Neurobiological correlates of intoxication and physical dependence upon ethanol: introductory remarks.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Brain; Ethanol; Humans; Male; Rats | 1981 |
Neurobiological and genetic aspects of the etiology of alcoholism.
Topics: Acetaldehyde; Alcohol Amnestic Disorder; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Bi | 1981 |
Lack of difference in blood acetaldehyde of alcoholics and controls after ethanol ingestion.
Topics: Acetaldehyde; Adult; Alcoholism; Ethanol; Humans; Male; Phenotype; Semicarbazides; Time Factors | 1980 |
Elevated blood acetaldehyde in alcoholics with accelerated ethanol elimination.
Topics: Acetaldehyde; Adult; Alcoholism; Breath Tests; Ethanol; Humans; Metabolic Clearance Rate; Middle Age | 1980 |
Biological markers: metabolism and acute reactions to alcohol in sons of alcoholics.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Ethanol; Humans; Male; Muscle Contraction; Prospec | 1980 |
[Alcohol and complications of alcoholism].
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Ethanol; Humans | 1981 |
[Is alcoholism hereditary? (author's transl)].
Topics: Acetaldehyde; Adoption; Alcohol Drinking; Alcoholism; Diseases in Twins; Ethanol; Female; Humans; Ma | 1981 |
Elevated blood acetaldehyde levels in alcoholics and their relatives: a reevaluation.
Topics: Acetaldehyde; Alcoholism; Hemolysis; Humans; Methods; Pedigree | 1980 |
Calcium carbimide--ethanol interaction.
Topics: Acetaldehyde; Adult; Alcoholism; Cyanamide; Cyanides; Drug Interactions; Ethanol; Heart Rate; Humans | 1980 |
[Development of the fetal alcohol syndrome].
Topics: Acetaldehyde; Alcoholism; Disulfiram; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Inf | 1980 |
Alcoholism and genetics: possible biological mediators.
Topics: Acetaldehyde; Adoption; Adult; Alcohol Drinking; Alcoholism; Arousal; Diseases in Twins; Ethanol; Fe | 1980 |
[Cerebral hemodynamics during treatment of chronic alcoholic patients with teturam].
Topics: Acetaldehyde; Adult; Alcoholism; Blood Pressure; Cerebrovascular Disorders; Disulfiram; Humans; Plet | 1980 |
A possible hemoglobin marker of alcoholism.
Topics: Acetaldehyde; Alcoholism; Deoxy Sugars; Erythrocytes; Glycolysis; Hemoglobins; Humans | 1980 |
Low acetaldehyde levels in blood, breath and cerebrospinal fluid of intoxicated humans as assayed by improved methods.
Topics: Acetaldehyde; Adult; Alcoholic Intoxication; Alcoholism; Brain Chemistry; Breath Tests; Humans; Male | 1980 |
Intraindividual variability in the calcium carbimide-ethanol interaction.
Topics: Acetaldehyde; Adult; Alcoholism; Aldehyde Oxidoreductases; Cyanamide; Cyanides; Drug Interactions; E | 1980 |
Cardiovascular changes during the calcium carbimide-ethanol interaction.
Topics: Acetaldehyde; Adult; Alcoholism; Cardiovascular System; Cyanamide; Cyanides; Disulfiram; Ethanol; Hu | 1981 |
Acetaldehyde adducts with hemoglobin.
Topics: Acetaldehyde; Alcoholism; Amino Acids; Chromatography, High Pressure Liquid; Chromatography, Ion Exc | 1981 |
Mechanisms of ethanol-induced suppression of a primary antibody response in a mouse model for binge drinking.
Topics: Acetaldehyde; Acetates; Alcoholism; Animals; Antibody Formation; Antibody-Producing Cells; Base Sequ | 1995 |
Ethanol and acetaldehyde metabolism in chinese with different aldehyde dehydrogenase-2 genotypes.
Topics: Acetaldehyde; Adolescent; Adult; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Genotype; Heterozygote | 1995 |
[The effect of combined toxicity on the development of alcoholic pancreatic lesions. A long-term experimental trial].
Topics: Acetaldehyde; Alcoholic Beverages; Alcoholism; Animals; Drug Synergism; Ethanol; Male; Methanol; Pan | 1995 |
Validated fluorimetric HPLC analysis of acetaldehyde in hemoglobin fractions separated by cation exchange chromatography: three new peaks associated with acetaldehyde.
Topics: Acetaldehyde; Alcoholism; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Fluoro | 1995 |
Antibodies from alcoholics, ethanol-fed rats and a rabbit immunised with proteins modified by acetaldehyde in vitro react with liver cytosolic proteins from ethanol-fed rats.
Topics: Acetaldehyde; Alcoholism; Animals; Autoantibodies; Autoantigens; Autoradiography; Blood Protein Elec | 1993 |
Heterogeneity of hepatic acetaldehyde adducts in guinea-pigs after chronic ethanol administration: an immunohistochemical analysis with monoclonal and polyclonal antibodies against acetaldehyde-modified protein epitopes.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies; Antibodies, Monoclonal; Cross Reactions; Enzyme-Linke | 1993 |
Antibodies made against a formaldehyde-protein adduct cross react with an acetaldehyde-protein adduct. Implications for the origin of antibodies in human serum which recognize acetaldehyde-protein adducts.
Topics: Acetaldehyde; Adult; Alcoholism; Animals; Antibodies; Blood Proteins; Cross Reactions; Epitopes; Fem | 1995 |
NMR investigation of the futile cycling of ethanol in chronic alcoholic rats.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Aldehyde Dehydrogenase; An | 1994 |
Acetaldehyde metabolism: differences between UChA and UChB rats.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Animals; Brain; Disulfiram; Isoenzymes; Liver; Mal | 1994 |
Antioxidant status in skeletal muscle and plasma of rats treated with ethanol.
Topics: Acetaldehyde; Alcoholism; Animals; Antioxidants; Cyanamide; Ethanol; Male; Rats; Rats, Wistar; Vitam | 1994 |
Detailed characterization of experimental acute alcoholic pancreatitis.
Topics: Acetaldehyde; Acute Disease; Alcoholism; Animals; Disease Models, Animal; Dogs; Free Radicals; Ische | 1995 |
Studies of the oxidation of ethanol to acetaldehyde by oxyhemoglobin using fluorigenic high-performance liquid chromatography.
Topics: Acetaldehyde; Alcoholism; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Et | 1994 |
Correlations between acetaldehyde-modified haemoglobin, carbohydrate-deficient transferrin (CDT) and haematological abnormalities in chronic alcoholism.
Topics: Acetaldehyde; Adult; Alcoholism; Bilirubin; Blood Cell Count; Enzymes; Erythrocyte Indices; Female; | 1994 |
Evidence for the formation of multiple types of acetaldehyde-haemoglobin adducts.
Topics: Acetaldehyde; Alcoholism; Biomarkers; Erythrocytes; Hemoglobins; Humans; Peptide Mapping; Peptides | 1994 |
Anti-acetaldehyde adduct antibodies generated by ethanol-fed rats react with reduced and unreduced acetaldehyde-modified proteins.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies; Binding Sites, Antibody; Cattle; Enzyme-Linked Immuno | 1994 |
Abnormal ethanol metabolism in Long-Evans Cinnamon rats, a mutant strain developing spontaneous hepatoma.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Animals; Cell Transformatio | 1993 |
Distribution and turnover of acetaldehyde-modified proteins in liver and blood of ethanol-fed rats.
Topics: Acetaldehyde; Alcoholism; Animals; Blood Proteins; Cytosol; Enzyme-Linked Immunosorbent Assay; Ethan | 1994 |
The kinetics of the addition of glucose and acetaldehyde to histone proteins.
Topics: Acetaldehyde; Alcoholism; Animals; Blood Glucose; Blood Proteins; Cattle; Diabetes Mellitus; Fructos | 1994 |
Comparative evaluation of the clinical utility of three markers of ethanol intake: the effect of gender.
Topics: Acetaldehyde; Adolescent; Adult; Alcoholism; beta-N-Acetylhexosaminidases; Ethanol; Female; gamma-Gl | 1993 |
Leucine and glucose turnover in chronic alcoholics during early abstinence and after an ethanol load.
Topics: Acetaldehyde; Acetates; Adult; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Blood Gluc | 1993 |
Brain GABA-transaminase and monoamine oxidase after chronic ethanol treatment in rats.
Topics: 4-Aminobutyrate Transaminase; Acetaldehyde; Alcoholism; Animals; Brain; Culture Techniques; Dose-Res | 1993 |
Ethanol and acetaldehyde metabolism in cultured rat hepatocytes.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Animals; Cells, Cultured; C | 1993 |
Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation.
Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Hepatitis, Alcoholic; Humans; Immunologic Techniques; Li | 1994 |
Detection of reduced acetaldehyde protein adducts using a unique monoclonal antibody.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies, Monoclonal; Antibody Specificity; Cattle; Cytosol; Li | 1994 |
Improved separation of acetaldehyde-induced hemoglobin.
Topics: Acetaldehyde; Alcoholism; Biomarkers; Chromatography, High Pressure Liquid; Hemoglobin A; Humans; Re | 1993 |
Measurement of hemoglobin-acetaldehyde adduct in alcoholic patients.
Topics: Acetaldehyde; Alcoholism; Enzyme-Linked Immunosorbent Assay; Female; Hemoglobins; Humans; Liver Dise | 1993 |
Acetaldehyde adducts and autoantibodies against VLDL and LDL in alcoholics.
Topics: Acetaldehyde; Alcoholism; Autoantibodies; Humans; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLD | 1993 |
Distribution of acetaldehyde in human blood: effects of ethanol and treatment with disulfiram.
Topics: Acetaldehyde; Adult; Alcoholism; Disulfiram; Ethanol; Female; Humans; Male; Protein Binding; Substan | 1993 |
Concentration and hydroxyapatite binding capacity of plasma osteocalcin in chronic alcoholic men: effect of a three-week withdrawal therapy.
Topics: Acetaldehyde; Adult; Alcoholism; Durapatite; Humans; Male; Middle Aged; Osteocalcin; Temperance | 1993 |
Zonal distribution of protein-acetaldehyde adducts in the liver of rats fed alcohol for long periods.
Topics: Acetaldehyde; Alcoholism; Animals; Cyanamide; Ethanol; Immunohistochemistry; Liver; Male; Proteins; | 1993 |
Determinants of ethanol and acetaldehyde metabolism in chronic alcoholics.
Topics: Acetaldehyde; Adult; Aged; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Femal | 1993 |
Effect of chronic alcohol feeding on hepatic iron status and ferritin uptake by rat hepatocytes.
Topics: Acetaldehyde; Alcoholism; Animals; Cells, Cultured; Ferritins; Iron; Liver; Liver Diseases, Alcoholi | 1993 |
Absence of evidence for mutagenicity of alcoholic beverages: an analysis of hprt mutant frequencies in 153 normal humans.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Biotransformation; Ethanol; | 1995 |
Influence of glutathione on the oxidation of 1-methyl-6-hydroxy-1,2,3,4-tetrahydro-beta-carboline: chemistry of potential relevance to the addictive and neurodegenerative consequences of ethanol use.
Topics: Acetaldehyde; Alcoholism; Ascorbic Acid; Brain; Carbolines; Catalase; Chromatography, High Pressure | 1996 |
Suppression of splenic natural killer cell activity in a mouse model for binge drinking. I. Direct effects of ethanol and its major metabolites are not primarily responsible for decreased natural killer cell activity.
Topics: Acetaldehyde; Acetates; Alcoholism; Animals; Cells, Cultured; Disease Models, Animal; Ethanol; Femal | 1996 |
Oxidation of circulating proteins in alcoholics: role of acetaldehyde and xanthine oxidase.
Topics: Acetaldehyde; Adult; Alcoholism; Blood Proteins; Erythrocytes; Glutathione; Humans; Male; Malondiald | 1996 |
A possible acetaldehyde-mediated cardioprotective mechanism.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Cells, Cultured; Coronary Disease; Endothelium, V | 1996 |
Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males.
Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; | 1996 |
Relationship between alcohol intake and immunoglobulin a immunoreactivity with acetaldehyde-modified bovine serum albumin.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Animals; Biomarkers; Cattle; Dose-Response Relati | 1996 |
Ethanol and acetaldehyde metabolism: past, present, and future.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Animals; Cytochrome P-450 E | 1996 |
Studies on the usefulness of acetaldehyde-modified proteins and associated antibodies as markers of alcohol abuse.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies; Biomarkers; Cattle; Female; Humans; Immunoglobulin A; | 1994 |
The chemical reactivity and structure of collagen studied by neutron diffraction.
Topics: Acetaldehyde; Aging; Alcoholism; Animals; Collagen; Crystallography; Deuterium; Diabetes Mellitus, T | 1996 |
Stable acetaldehyde adducts: structural characterization of acetaldehyde adducts of human hemoglobin N-terminal beta-globin chain peptides.
Topics: Acetaldehyde; Alcoholism; Gas Chromatography-Mass Spectrometry; Globins; Hemoglobins; Humans; Magnet | 1997 |
The formation and measurement of DNA neuroadduction in alcoholism. Case report.
Topics: Acetaldehyde; Adult; Alcoholism; Astrocytes; Brain; Cells, Cultured; Chromatography, Thin Layer; DNA | 1997 |
Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers.
Topics: Acetaldehyde; Adult; Alcoholism; DNA; DNA Adducts; Female; Granulocytes; Humans; Lymphocytes; Male; | 1997 |
Effects of lifelong ethanol consumption on cerebellar layer volumes in AA and ANA rats.
Topics: Acetaldehyde; Age Factors; Alcoholism; Animals; Brain Mapping; Cerebellar Cortex; Cerebellum; Ethano | 1997 |
Manipulation of alcohol drinking by liver transplantation.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Animals; Ethanol; Liver Cirrhosi | 1997 |
Transglutaminase activity in rat brain after ethanol exposure.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Animals; Brain; Dose-Response Relationship, Drug; | 1997 |
[Acetaldehyde adducts in the cerebral cortex of ethanol-fed mice].
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Disease Models, Animal; Immunohistochemistry; Male; Mice; | 1997 |
Clinical characteristics and disease course of alcoholics with inactive aldehyde dehydrogenase-2.
Topics: Acetaldehyde; Adult; Aged; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial | 1998 |
Free radicals and not acetaldehyde influence the circulating levels of glutathione after acute or chronic alcohol abuse: in vivo and in vitro studies.
Topics: Acetaldehyde; Acute Disease; Adult; Alcoholic Intoxication; Alcoholism; Chronic Disease; Erythrocyte | 1997 |
Detection of circulating antibodies to malondialdehyde-acetaldehyde adducts in ethanol-fed rats.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies; Antibody Formation; Antibody Specificity; Enzyme-Link | 1998 |
Prevalence of ethanol consumption may be higher in women than men in a university health service population as determined by a biochemical marker: whole blood-associated acetaldehyde above the 99th percentile for teetotalers.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Female; Humans; Male; Reference Value | 1998 |
Monoclonal and polyclonal antibodies recognizing acetaldehyde-protein adducts.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies; Antibodies, Monoclonal; Antibody Specificity; Antigen | 1998 |
Evaluation of acetaldehyde-modified hemoglobin and other markers of chronic heavy alcohol use: effects of gender and hemoglobin concentration.
Topics: Acetaldehyde; Adult; Alcoholism; Biomarkers; Female; Glycated Hemoglobin; Hemoglobinometry; Hemoglob | 1998 |
Comparison of carbohydrate-deficient transferrin, immunoglobulin A antibodies reactive with acetaldehyde-modified protein and acetaldehyde-modified albumin with conventional markers of alcohol consumption.
Topics: Acetaldehyde; Adult; Alcoholism; Biomarkers; Blood Proteins; Diagnosis, Differential; Female; Humans | 1998 |
Ethanol and acetaldehyde inhibit the formation of early osteoblast progenitors in murine and human bone marrow cultures.
Topics: Acetaldehyde; Alcoholism; Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Line; Central | 1999 |
Coagulation protein function: the influence of acetaldehyde-modified heparin on thrombin activity.
Topics: Acetaldehyde; Alcoholism; Animals; Cattle; Heparin; Humans; In Vitro Techniques; Thrombin; Thrombin | 1999 |
Regulation of alcohol and aldehyde dehydrogenase activity: a metabolic balancing act with important social consequences.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrog | 1999 |
[The characteristics of the metabolic and psychophysiological disorders in patients in different stages of chronic alcoholism].
Topics: Acetaldehyde; Adult; Alcoholism; Catecholamines; Ethanol; Higher Nervous Activity; Humans; Male; Psy | 1999 |
Coagulation protein function VI: augmentation of anticoagulant function by acetaldehyde-treated heparin.
Topics: Acetaldehyde; Alcoholism; Anticoagulants; Antithrombins; Blood Coagulation; Blood Coagulation Factor | 1999 |
Accumulation of hemoglobin-associated acetaldehyde with habitual alcohol drinking in the atypical ALDH2 genotype.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogena | 2000 |
[Acetaldehyde adducts in the cerebral cortex of long-term ethanol-fed mice].
Topics: Acetaldehyde; Alcoholism; Animals; Cerebral Cortex; Female; Immunohistochemistry; Liver; Mice; Mice, | 1999 |
Involvement of acetaldehyde for full protection against alcoholism by homozygosity of the variant allele of mitochondrial aldehyde dehydrogenase gene in Asians.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Alleles; Area Under Curve | 1999 |
The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure.
Topics: Acetaldehyde; Alcoholism; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Incidence; Infa | 2001 |
Coagulation protein function: enhancement of the anticoagulant effect of acetaldehyde by sulfated glycosaminoglycans.
Topics: Acetaldehyde; Alcoholism; Blood Coagulation; Blood Coagulation Tests; Chondroitin Sulfates; Dermatan | 2001 |
Assays for acetaldehyde-derived adducts in blood proteins based on antibodies against acetaldehyde/lipoprotein condensates.
Topics: Acetaldehyde; Adult; Alcoholism; Animals; Antibodies; Antibody Specificity; Blood Proteins; Epitopes | 2001 |
Chronic alcoholism: a common risk factor in oral cancer and alcoholic cirrhosis.
Topics: Acetaldehyde; Adult; Alcoholism; Black People; Carcinogens; Ethanol; Female; Hepatocytes; Humans; Li | 2001 |
Concentration of ethanol and other volatile compounds in the blood of acutely poisoned alcoholics.
Topics: 1-Propanol; 2-Propanol; Acetaldehyde; Acetone; Adolescent; Adult; Aged; Alcoholic Intoxication; Alco | 2002 |
Short- and long-term effects of acetaldehyde on plasma.
Topics: Acetaldehyde; Alcoholism; Blood Coagulation; Humans; Partial Thromboplastin Time; Prothrombin Time; | 2002 |
Mitochondrial oxidative stress and CD95 ligand: a dual mechanism for hepatocyte apoptosis in chronic alcoholism.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Animals; Apoptosis; Cells, Cultured; Central Nervo | 2002 |
[Alcohol-induced morphologic and biochemical corneal changes].
Topics: Acetaldehyde; Alcoholism; Amino Acid Isomerases; Aspartic Acid; Cell Count; Cornea; Corneal Stroma; | 2002 |
Developmental changes in the brain levels of neurotransmitters as influenced by maternal ethanol consumption in the rat.
Topics: 4-Aminobutyrate Transaminase; Acetaldehyde; Acetylcholine; Alcoholism; Animals; Animals, Newborn; Br | 1977 |
[Biochemical and pathophysiological aspects of alcohol metabolism (author's transl)].
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Aldehyde Oxidoreductases; Catalase; Ethanol; Huma | 1978 |
The pathophysiology of alcohol and acetaldehyde metabolism in the liver.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Ethanol; Hepatitis, Alcoholic; Humans; I | 1978 |
[Biochemical mechanisms for the effect of alcohol on the brain].
Topics: Acetaldehyde; Adenylyl Cyclases; Alcohol Drinking; Alcoholism; Animals; Brain; Calcium-Transporting | 1979 |
Inhibition of cardiac protein synthesis by prolonged ethanol administration.
Topics: Acetaldehyde; Alcoholism; Animals; Cycloheximide; Disulfiram; DNA; Ethanol; Female; Humans; Hydrogen | 1979 |
Alcoholic hepatitis, cirrhosis, and immunologic reactivity.
Topics: Acetaldehyde; Alcoholism; B-Lymphocytes; Cells, Cultured; Chemical and Drug Induced Liver Injury; Co | 1975 |
Lymphocyte cytotoxicity in alcoholic hepatitis.
Topics: Acetaldehyde; Alcoholism; Antigen-Antibody Reactions; Biopsy; Cell Line; Culture Techniques; Cytotox | 1977 |
Molecular injury to mitochondria produced by ethanol and acetaldehyde.
Topics: Acetaldehyde; Adenosine Triphosphatases; Alcohol Oxidoreductases; Alcoholism; Animals; Aspartic Acid | 1975 |
Studies on the effects of pyrogallol and the structurally related dopa decarboxylase inhibitor RO4-4602 on acetaldehyde metabolism.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Animals; Benserazide; Chloral Hydrate; Ditiocarb | 1976 |
[Chemical mechanism of the effect of alcohol].
Topics: Acetaldehyde; Alcoholism; Animals; Berberine Alkaloids; Biogenic Amines; Ethanol; Humans; Isoquinoli | 1979 |
Metabolic consequences of chronic alcohol consumption: attenuation of hepatic redox changes despite enhanced capacity to eliminate ethanol.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Cytosol; Ethanol; Galactose; Haplorhini; | 1979 |
Biomedical issues and clinical effects of alcoholism. Introduction of mechanisms of addiction.
Topics: Acetaldehyde; Alcoholism; Humans; Liver; NAD | 1979 |
Alcohol and aldehyde dehydrogenase on chronic ethanol intoxication. Effect of acetaldehyde and fat diet [proceedings].
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Aldehyde Oxidoreductases; Animals; Dietary Fats; | 1979 |
Some promising fields of inquiry in biomedical alcohol research.
Topics: Acetaldehyde; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholism; Animals; Female; Fetal Alcohol | 1979 |
Relationship between 3,4-dihydroxyphenylacetaldehyde levels and tetrahydropapaveroline formation.
Topics: Acetaldehyde; Alcoholism; Animals; Brain Chemistry; Dopamine; Humans; Monoamine Oxidase; Papaverine; | 1978 |
[Pathobiochemistry of alcoholism].
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Genetic Variation; Humans; Liver; Phenotype; Poly | 1979 |
Dopamine-related tetrahydroisoquinolines: significant urinary excretion by alcoholics after alcohol consumption.
Topics: Acetaldehyde; Adult; Alcoholism; Dopamine; Humans; Isoquinolines; Male; Middle Aged; Salsoline Alkal | 1979 |
Alcoholism: an overview of biomedical issues.
Topics: Acetaldehyde; Alcoholism; Ethanol; Hormones; Humans; Nutritional Physiological Phenomena | 1979 |
Some biochemical aspects of chronic alcohol intoxication.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Biogenic Amines; Ethanol; Humans | 1977 |
Common mechanism for the adaptive increase in hepatic ethanol and acetaldehyde metabolism due to chronic pretreatment with ethanol.
Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Humans; Liver; Mitochondria, Liver; Ouabain; Oxygen Cons | 1977 |
The liver: a pharmacologic perspective.
Topics: Acetaldehyde; Alcoholism; Chemical and Drug Induced Liver Injury; Diuretics; Drug-Related Side Effec | 1977 |
The alcohol syndromes: the intrarecombigenic effect of acetaldehyde.
Topics: Acetaldehyde; Alcoholism; Cells, Cultured; Chromatids; Disulfiram; Ethanol; Humans; Lymphocytes; Mit | 1978 |
On the probability of implanted disulfiram's causing a reaction to ethanol.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Animals; Disulfiram; Dose-Response Relationship, | 1978 |
Lack of evidence for sustained blood acetaldehyde concentrations during alcohol detoxification.
Topics: Acetaldehyde; Adult; Alcoholism; Ethanol; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; | 1978 |
Aldehyde dehydrogenase in human blood.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Chromatography, Gel; Electrophoresis, Starch Gel | 1978 |
[Effect of ethanol and its metabolite acetaldehyde on the chromosomal apparatus of rat and human cells].
Topics: Acetaldehyde; Adult; Alcoholism; Aneuploidy; Animals; Chromosome Aberrations; Ethanol; Humans; Leuko | 1978 |
Ethanol ingestion: differences in blood acetaldehyde concentrations in relatives of alcoholics and controls.
Topics: Acetaldehyde; Adult; Alcoholism; Ethanol; Humans; Male; Pedigree | 1979 |
A mechanism for decreased resistance to infection by gram-negative organisms during acute alcoholic intoxication.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Animals; Bacteria; Bacterial Infections; Blood Bac | 1975 |
[Severe intoxication probably caused by acetaldehyde as the result of the disulfiram-ethanol reaction].
Topics: Acetaldehyde; Adult; Alcoholism; Disulfiram; Drug Interactions; Ethanol; Humans; Male | 1976 |
[Oxidative enzymes of acetaldehyde in the liver : their characteristics and effect of chronic ethanol consumption on the acetaldehyde metabolism (author's transl)].
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Animals; Humans; Liver; Mitochondria, Liver; Oxy | 1976 |
The pathogenesis of alcoholic hepatitis and cirrhosis.
Topics: Acetaldehyde; Alcoholism; Animals; Autoantibodies; Female; Hepatitis; Humans; Immunity, Cellular; Im | 1976 |
Biologic aspects of alcohol: an introduction.
Topics: Acetaldehyde; Alcoholism; Calcium; Dopamine beta-Hydroxylase; Ethanol; Humans; Racial Groups | 1976 |
High blood acetaldehyde levels after ethanol administration. Difference between alcoholic and nonalcoholic subjects.
Topics: Acetaldehyde; Adult; Alcoholism; Chromatography; Chromatography, Gas; Ethanol; Humans; Injections, I | 1975 |
Editorial: Alcoholism or acetaldehydism?
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Dose-Response Relationship, Drug; Ethanol; Human | 1975 |
Letter: Toxic potential of aldehyde in man.
Topics: Acetaldehyde; Alcoholism; Animals; Depression, Chemical; Humans; In Vitro Techniques; Lactates; Rats | 1975 |
[Interaction between alcohol and drugs (author's transl)].
Topics: Acetaldehyde; Acute Disease; Alcohol Oxidoreductases; Alcoholism; Aldehyde Oxidoreductases; Analgesi | 1975 |
Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking.
Topics: Acetaldehyde; Acetylcysteine; Alcoholism; Anesthetics; Animals; Ascorbic Acid; Cysteine; Humans; Let | 1975 |
Alcoholic cardiomyopathy: the effect of ethanol and acetaldehyde on cardiac protein synthesis.
Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Guinea Pigs; Heart Diseases; Humans; In Vitro Techniques | 1975 |
Hemoglobin-acetaldehyde adducts in human alcohol abusers.
Topics: Acetaldehyde; Adult; Aged; Alcoholism; Enzyme-Linked Immunosorbent Assay; Epitopes; Erythrocytes; Fe | 1992 |
The identification and partial characterization of acetaldehyde adducts of hemoglobin occurring in vivo: a possible marker of alcohol consumption.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Chromatography, High Pressure Liquid; Erythrocyte | 1992 |
Relationship between blood catalase activity and drinking history in a human population, a possible biological marker of the affinity to consume alcohol.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Catalase; Female; Humans; Illicit Dru | 1992 |
Optimized spectrophotometric determination of aldehyde dehydrogenase activity in erythrocytes.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehydes; Drug Stability; Erythrocytes; Humans; K | 1992 |
Acetaldehyde, ethanol and acetone concentrations in blood of alcohol-treated mice receiving aldehyde dehydrogenase-loaded erythrocytes.
Topics: Acetaldehyde; Acetone; Alcoholism; Aldehyde Dehydrogenase; Animals; Blood Component Transfusion; Ery | 1992 |
Acetaldehyde measurement in RBCs: potential new marker for alcohol abuse.
Topics: Acetaldehyde; Alcoholism; Biomarkers; Erythrocytes; Humans | 1992 |
Method of acetaldehyde measurement with minimal artifactual formation in red blood cells and plasma of actively drinking subjects with alcoholism.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Artifacts; Centrifugation; Chromatography, Gas; Chromato | 1992 |
Acetaldehyde-modified hemoglobin as a marker of alcohol consumption: comparison of two new methods.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Chromatography, Liquid; Hemoglobins; | 1992 |
Reaction of acetaldehyde with human platelets.
Topics: Acetaldehyde; Alcoholism; Binding Sites; Blood Platelets; Ethanol; Humans; In Vitro Techniques; Plat | 1992 |
Antibodies against acetaldehyde-modified epitopes: an elevated IgA response in alcoholics.
Topics: Acetaldehyde; Alcoholism; Epitopes; Hemoglobins; Humans; Immunoglobulin A; Liver; Liver Diseases; Li | 1991 |
The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis.
Topics: Acetaldehyde; Acute Disease; Alcoholism; Amylases; Animals; Dogs; Free Radicals; In Vitro Techniques | 1991 |
[Acetaldehyde in the cardiotoxic mechanism of action of alcohol: effects on cardiac and adrenal catecholamines].
Topics: Acetaldehyde; Adrenal Glands; Alcoholism; Animals; Catecholamines; Epinephrine; Ethanol; Heart; Myoc | 1991 |
Urinary markers of chronic excessive ethanol consumption.
Topics: Acetaldehyde; Alcoholism; Creatinine; Ethanol; Gas Chromatography-Mass Spectrometry; Hospitalization | 1991 |
Association of a haemoglobin-acetaldehyde adduct with questionnaire results on heavy drinkers.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Glycated Hemoglobin; Hemoglobins; Hum | 1991 |
Glycoprotein glycosyltransferase activities in serum in alcohol-abusing patients and healthy controls.
Topics: Acetaldehyde; Adult; Alcoholism; beta-D-Galactoside alpha 2-6-Sialyltransferase; Galactosyltransfera | 1991 |
Acetaldehyde-modified proteins and associated antibodies in ethanol-fed rats.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies; Antibody Formation; Blood Proteins; Enzyme-Linked Imm | 1991 |
Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Cattle; Enzyme-Linked Immunosorbent Assay; Hemo | 1991 |
Formation of the 37KD liver protein-acetaldehyde adduct in vivo and in vitro.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Animals; Cells, Cultured; Chromatography, Affinity | 1991 |
Degrees of alcohol intoxication in 117 hospitalized cases.
Topics: Acetaldehyde; Adult; Aged; Alcoholic Intoxication; Alcoholism; Ethanol; Flushing; Hospitalization; H | 1991 |
Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Ethanol; Genetic Carrier Screening; Genotype; Ho | 1991 |
The effect of alcohol and anesthetic metabolites on cell membranes. A possible direct immune mechanism.
Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Cell Membrane; Chemical and Drug Induced Live | 1991 |
Formation of a protein-acetaldehyde adduct in liver during chronic alcohol exposure.
Topics: Acetaldehyde; Alcoholism; Animals; Cyanamide; In Vitro Techniques; Liver; Male; Molecular Weight; Pr | 1991 |
Abnormal low density lipoproteins composition in some chronic alcoholics: a possible mechanism.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Apolipoproteins B; Cholesterol; Ethanol; Female; | 1990 |
Use of leukocyte aldehyde dehydrogenase activity to monitor inhibitory effect of disulfiram treatment.
Topics: Acetaldehyde; Adult; Alcoholism; Aldehyde Dehydrogenase; Disulfiram; Erythrocytes; Female; Humans; L | 1990 |
Aldehyde dehydrogenases and alcoholism.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Cross-Cultural Comparison; Flushing; Humans | 1990 |
Ethanol-inducible cytochrome P-450 activity and increase in acetaldehyde bound to microsomes after chronic administration of acetaldehyde or ethanol.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Cytochrome P-450 Enzyme System; Enzyme I | 1990 |
Formation of the 37KD protein-acetaldehyde adduct in liver during alcohol treatment is dependent on alcohol dehydrogenase activity.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Cells, Cultured; | 1990 |
Detection of acetaldehyde-modified proteins in the livers of ethanol-fed rats.
Topics: Acetaldehyde; Alcoholism; Animals; Cytosol; Ethanol; Immunochemistry; Liver; Proteins; Rats | 1990 |
Ethanol and acetaldehyde metabolism in cultured hepatocytes from chronic alcoholic rats.
Topics: Acetaldehyde; Alcoholism; Animals; Cells, Cultured; Culture Media; Ethanol; Liver; Male; Oxidation-R | 1990 |
The influence of cyclosporine on abstinence from alcohol in transplant patients.
Topics: Acetaldehyde; Alcoholism; Animals; Cyclosporins; Ethanol; In Vitro Techniques; Liver; Liver Transpla | 1990 |
Protein-acetaldehyde adducts in serum of alcoholic patients.
Topics: Acetaldehyde; Alcoholism; Enzyme-Linked Immunosorbent Assay; Hemoglobins; Humans; Infant, Newborn; M | 1990 |
Alterations in the regulatory properties of hepatic fatty acid oxidation and carnitine palmitoyltransferase I activity after ethanol feeding and withdrawal.
Topics: Acetaldehyde; Acyltransferases; Alcoholism; Animals; Carnitine O-Palmitoyltransferase; Ethanol; Fatt | 1990 |
Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts.
Topics: Acetaldehyde; Alcoholism; Animals; Antibodies, Monoclonal; Antibody Formation; Blood Proteins; Epito | 1986 |
Ethanol induces the production of antibodies to acetaldehyde-modified epitopes in rats.
Topics: Acetaldehyde; Alcoholism; Animals; Autoantibodies; Autoantigens; Carrier Proteins; Epitopes; Ethanol | 1989 |
[Various biochemical mechanisms of alcoholic liver cirrhosis].
Topics: Acetaldehyde; Alcoholism; Europe; Free Radicals; Humans; Lipid Peroxides; Liver; Liver Cirrhosis | 1989 |
Altered ultrastructure of lactating rat mammary epithelial cells induced by chronic ethanol ingestion.
Topics: Acetaldehyde; Alcoholism; Animals; Epithelium; Ethanol; Female; Lactation; Mammary Glands, Animal; M | 1989 |
Comparative study on ethanol elimination and blood acetaldehyde between alcoholics and control subjects.
Topics: Acetaldehyde; Adult; Aged; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Humans; Liver Diseases, Alco | 1989 |
Characterization of the increased binding of acetaldehyde to red blood cells in alcoholics.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Binding Sites; Binding, Competitive; Erythrocytes; | 1989 |
Correlations between serum proteins modified by acetaldehyde and biochemical variables in heavy drinkers.
Topics: Acetaldehyde; Adult; Alcoholism; Aspartate Aminotransferases; Biomarkers; Blood Proteins; Female; Hu | 1989 |
Placental alcohol metabolism in chronic alcohol abuse.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Female; Humans; Pl | 1989 |
[Biochemical mechanisms of cell lesions in alcoholism].
Topics: Acetaldehyde; Acetates; Alcoholic Intoxication; Alcoholism; Ethanol; Free Radicals; Humans; Microsom | 1989 |
[New aspects of acetaldehyde metabolism in human tissues and erythrocytes].
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Erythrocytes; Humans; Tissue Distribution | 1989 |
Inborn alcoholism.
Topics: Acetaldehyde; Alcoholism; Humans | 1985 |
Increased excretion of harman by alcoholics depends on events of their life history and the state of the liver.
Topics: Acetaldehyde; Adult; Alcoholism; Alkaloids; Analysis of Variance; Ethanol; Female; gamma-Glutamyltra | 1985 |
[Biochemical aspects of dependence on alcohol].
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Ethanol; Membrane Fluidity; Membrane Lipids; Membrane Prot | 1985 |
Red cell morphology in alcoholics: a new test for alcohol abuse.
Topics: Acetaldehyde; Adult; Alcoholism; Aspartate Aminotransferases; Erythrocyte Volume; Erythrocytes; Eryt | 1986 |
Haptenisation of serum proteins by acetaldehyde.
Topics: Acetaldehyde; Alcoholism; Blood Proteins; Haptens; Humans | 1986 |
Blood acetaldehyde and ethanol levels in alcoholism.
Topics: Acetaldehyde; Adult; Alcoholism; Alkaline Phosphatase; Aspartate Aminotransferases; Ethanol; Female; | 1987 |
[Renal handling of alcohol and its tubular effects].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Aldehyde Dehydrogenase; An | 1985 |
Alcohol, acetaldehyde and salsolinol-induced alterations in function and metabolism of cerebral GABAergic and cholinergic neurons: possible involvements in alcohol dependence and withdrawal.
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Cells, Cultured; Cerebral Cortex; Ethanol; Isoquinolines; | 1987 |
A nonhypoglycemic chlorpropamide analog that inhibits aldehyde dehydrogenase.
Topics: Acetaldehyde; Alcohol Deterrents; Alcoholism; Aldehyde Dehydrogenase; Animals; Blood Glucose; Chlorp | 1988 |
Investigation of an acetaldehyde-hemoglobin adduct in alcoholics.
Topics: Acetaldehyde; Alcoholism; Blood Protein Electrophoresis; Chromatography, Affinity; Chromatography, H | 1988 |
Humoral immune response to acetaldehyde adducts in alcoholic patients.
Topics: Acetaldehyde; Alcoholism; Antibodies; Hemagglutination Tests; Hemocyanins; Humans; Immunodiffusion; | 1986 |
Acute and chronic effects of ethanol and its metabolites on vascular production of prostacyclin in rats.
Topics: Acetaldehyde; Acetates; Acetic Acid; Alcohol Dehydrogenase; Alcoholism; Animals; Arachidonic Acid; A | 1987 |
Role of macrophages in the pathogenesis of alcohol induced tissue damage.
Topics: Acetaldehyde; Alcoholism; Ethanol; Humans; Liver; Macrophages; Nerve Tissue | 1987 |
Detection of a protein-acetaldehyde adduct in the liver of rats fed alcohol chronically.
Topics: Acetaldehyde; Alcoholism; Animals; Immunodiffusion; Immunosorbent Techniques; Liver; Molecular Weigh | 1988 |
Relationship between ethanol, HDL, and vascular prostacyclin production.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaldehyde; Acetates; Alcohol Drinking; Alcoholism; Animals; Aorta; | 1987 |
Ethanol decreases plasma sulphydryls in man: effect of disulfiram.
Topics: Acetaldehyde; Adult; Alcoholism; Cysteine; Disulfiram; Drug Interactions; Ethanol; Female; Glutathio | 1988 |
Induction of an allergic reaction to alcohol metabolites by immunization.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Animals; Cyanamide; Disulfiram; Drug Hypersensitiv | 1988 |
Metabolic effects of acetaldehyde.
Topics: Acetaldehyde; Alcoholism; Cell Membrane; Cysteine; Glutathione; Humans; Intracellular Membranes; Iro | 1988 |
[Metabolism of ethanol and influencing factors].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Animals; Ethanol; Humans; Microsomes | 1988 |
[Early diagnosis of alcoholism].
Topics: Acetaldehyde; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Ethanol; Humans; Lipids | 1988 |
Effect of abstinence on the blood acetaldehyde response to a test dose of alcohol in alcoholics.
Topics: Acetaldehyde; Adult; Alcoholism; Ethanol; Humans; Male; Temperance | 1987 |
Acetaldehyde adducts with haemoglobin: determination of acetaldehyde released from haemoglobin by acid hydrolysis.
Topics: Acetaldehyde; Adult; Aged; Alcoholism; Carbon Radioisotopes; Chromatography, High Pressure Liquid; H | 1988 |
Acetaldehyde-albumin adduct formation: possible relevance to an immunologic mechanism in alcoholism.
Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Enzyme-Linked Immunosorbent Assay; Haptens; H | 1988 |
Similar antagonistic effects of Ca N-acetylhomotaurinate on depression of motor activity and lethality induced by acetaldehyde or ethanol.
Topics: Acamprosate; Acetaldehyde; Alcoholism; Amino Acids, Sulfur; Animals; Cations; Ethanol; Male; Mice; M | 1988 |
Transport of acetaldehyde in red blood cells.
Topics: Acetaldehyde; Alcoholism; Animals; Biological Transport; Erythrocytes; Ethanol; Humans; Papio | 1987 |
Can brain lesions occur in experimental animals by administration of ethanol or acetaldehyde?
Topics: Acetaldehyde; Administration, Inhalation; Alcoholism; Animals; Brain; Disease Models, Animal; Disulf | 1987 |
Application of isoelectric focusing in immobilized pH gradients to the study of acetaldehyde-modified hemoglobin.
Topics: Acetaldehyde; Alcoholism; Borohydrides; Chemical Phenomena; Chemistry; Erythrocytes; Fructosediphosp | 1986 |
[Alcohol: biochemistry and health].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Ethanol; Humans; Liver; Liv | 1987 |
[Endogenous ethanol and its possible participation in the activity of the central nervous system in healthy subjects and alcoholics].
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholism; Ambulatory Care; Disulfiram; Emotions; Ethanol; Hos | 1987 |
Metabolic pathways leading to diol formation.
Topics: Acetaldehyde; Acetoin; Alcoholism; Butylene Glycols; Chemical Phenomena; Chemistry; Ethanol; Humans; | 1987 |
Effects of acetaldehyde condensation products on human platelet aggregation.
Topics: Acetaldehyde; Adenosine Diphosphate; Alcoholism; Carbolines; Epinephrine; Ethanol; Humans; In Vitro | 1987 |
Sensitivity of human lymphocytes to acetaldehyde: comparison between alcoholic and control subjects.
Topics: Acetaldehyde; Adult; Alcoholism; Cells, Cultured; Dose-Response Relationship, Drug; Female; Humans; | 1987 |
Alcohol and acetaldehyde in rat's milk following ethanol administration.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Animals; Ethanol; Female; Kineti | 1986 |
An examination of selected typologies. Hyperactivity, familial, and antisocial alcoholism.
Topics: Acetaldehyde; Adolescent; Adoption; Adult; Alcoholism; Antisocial Personality Disorder; Arousal; Att | 1986 |
Acetaldehyde adducts with serum proteins are not responsible for decreased drug binding in alcoholic patients.
Topics: Acetaldehyde; Adult; Albumins; Alcoholism; Blood Proteins; Diazepam; Female; Humans; Male; Middle Ag | 1986 |
Acute and chronic effect of ethanol on hepatic albumin synthesis in rat liver in vitro.
Topics: Acetaldehyde; Albumins; Alcoholic Intoxication; Alcoholism; Animals; Chromatography, DEAE-Cellulose; | 1986 |
Determination of free acetaldehyde in blood as the dinitrophenylhydrazone derivative by high-performance liquid chromatography.
Topics: Acetaldehyde; Adult; Alcoholism; Chromatography, High Pressure Liquid; Ethanol; Humans; Hydrazones; | 1986 |
Red blood cells: a new major modality for acetaldehyde transport from liver to other tissues.
Topics: Acetaldehyde; Alcoholism; Animals; Erythrocytes; Humans; Liver; Papio; Splanchnic Circulation | 1987 |
Tetrahydro-beta-carbolines in human urine and rat brain--no evidence of formation by alcohol drinking.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Animals; Brain; Carbolines; Female; Gas Chromatog | 1986 |
[Alcohol and metabolism].
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Amino Acids; Blood Glucose; Cholesterol; Energy Metaboli | 1985 |
Investigation into the substrate capacity of the acetaldehyde-tetrahydrofolate condensation product.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; | 1985 |
Alcohol abuse: detection of acetaldehyde adducts in rat urine following administration of erythrocytes labelled with radioactive acetaldehyde.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Erythrocytes; Ethanol; Female; Rats; Rat | 1985 |
Acetaldehyde adducts with serum proteins: effect on diazepam and phenytoin binding.
Topics: Acetaldehyde; Alcoholism; Binding Sites; Blood Proteins; Diazepam; Ethanol; Humans; In Vitro Techniq | 1986 |
Endogenous breath acetaldehyde levels among alcoholic and non-alcoholic probands: effect of alcohol use and smoking.
Topics: Acetaldehyde; Adolescent; Adult; Aged; Aging; Alcohol Drinking; Alcoholism; Breath Tests; Female; Hu | 1985 |
Elevated endogenous breath acetaldehyde levels among abusers of alcohol and cigarettes.
Topics: Acetaldehyde; Adult; Alcoholism; Breath Tests; Humans; Middle Aged; Smoking | 1985 |
The role of salsolinol in alcohol intake and withdrawal.
Topics: Acetaldehyde; Alcoholism; Ethanol; Humans; Isoquinolines; Levodopa; Male; Middle Aged; Substance Wit | 1985 |
Lipid peroxidation in ethanol poisoning: a critical reconsideration.
Topics: Acetaldehyde; Alcoholism; Animals; Ethanol; Fatty Acids, Nonesterified; Fatty Liver, Alcoholic; Free | 1985 |
Lowering of liver acetaldehyde but not ethanol concentrations by pretreatment with taurine in ethanol-loaded rats.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Animals; Enzyme Activation; Ethanol; Liver; Male; | 1985 |
Alcohol addiction: a biochemical approach.
Topics: Acetaldehyde; Alcoholism; Alkaloids; Amines; Biogenic Amines; Ethanol; Humans; Hydroxyindoleacetic A | 1972 |
The induction of ethanol dependence and the ethanol withdrawal syndrome: the effects of pyrazole.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Body Weight; Brain Chemistry; Disease Mo | 1974 |
A comparison of the effects of chronic administration of ethanol and acetaldehyde to mice: evidence for a role of acetaldehyde in ethanol dependence.
Topics: Acetaldehyde; Aerosols; Alcoholism; Animals; Behavior, Animal; Brain; Brain Chemistry; Dopamine; Eth | 1974 |
Is there a biochemical lesion in the disease of alcoholism?
Topics: Acetaldehyde; Alcoholism; Animals; Humans; Mice; NAD; Rats | 1970 |
Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes.
Topics: Acetaldehyde; Adolescent; Adult; Age Factors; Aged; Alcohol Oxidoreductases; Alcoholism; Erythrocyte | 1974 |
A further insight into the metabolism of certain -carbolines.
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Ethanol; Humans; Indoles; Male; Pyridines; Rats; Serotonin | 1973 |
Biogenesis of biologically active alkaloids from amines by alcohol and acetaldehyde.
Topics: Acetaldehyde; Alcoholism; Alkaloids; Amines; Animals; Biogenic Amines; Biotransformation; Brain; Cat | 1973 |
Ethanol and methanol metabolites in alcohol withdrawal.
Topics: Acetaldehyde; Adult; Aged; Alcoholism; Behavior; Chromatography, Gas; Ethanol; Female; Formates; Hum | 1973 |
Lymphocyte transformation and alcoholic liver injury.
Topics: Acetaldehyde; Alcoholism; Cells, Cultured; Chemical and Drug Induced Liver Injury; DNA; Ethanol; Fat | 1972 |
Ethanol, acetaldehyde, and myocardial protein synthesis.
Topics: Acetaldehyde; Albumins; Alcoholism; Animals; Carbon Isotopes; Depression, Chemical; Ethanol; Guinea | 1972 |
[Adrenal cortex and thyroid gland activity in alcoholism and polytoxicomania].
Topics: 17-Ketosteroids; Acetaldehyde; Adrenal Glands; Adult; Aged; Alcoholism; Blood Proteins; Ethanol; Fem | 1973 |
[Acetaldehyde and alcoholism. The pharmacogenesis of the teturam-alcohol reaction and its control by way of binding acetaldehyde with sodium metabisulfite].
Topics: Acetaldehyde; Adult; Alcoholic Intoxication; Alcoholism; Animals; Disulfiram; Humans; Mice; Sulfites | 1973 |
Ethanol-induced release of acetaldehyde from blood and its effect on the determination of acetaldehyde.
Topics: Acetaldehyde; Alcoholism; Animals; Cattle; Chromatography, Gas; Dogs; Ethanol; Haplorhini; Humans; M | 1970 |
Blood methanol concentrations during experimentally induced ethanol intoxication in alcoholics.
Topics: Acetaldehyde; Acetone; Adult; Alcoholic Beverages; Alcoholic Intoxication; Alcoholism; Chromatograph | 1971 |
Effects of congener differences in alcoholic beverages on the behavior of alcoholics.
Topics: Acetaldehyde; Acetates; Adult; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Alcohols; Anxiety; | 1970 |
Alkaloids from catecholamines in adrenal tissue: possible role in alcoholism.
Topics: Acetaldehyde; Adrenal Glands; Alcoholism; Alkaloids; Animals; Cattle; Chromatography, Thin Layer; Ep | 1970 |
Blood concentrations of acetaldehyde and ethanol in chronic alcoholics.
Topics: Acetaldehyde; Alcoholic Beverages; Alcoholism; Chronic Disease; Ethanol; Humans | 1970 |
Toxic volatiles in alcoholic coma. A report of simultaneous determination of blood methanol, ethanol, isopropanol, acetaldehyde and acetone by gas chromatography.
Topics: 1-Propanol; Acetaldehyde; Acetone; Alcoholism; Chromatography, Gas; Coma; Ethanol; Humans; Methanol; | 1968 |