acetaldehyde has been researched along with Aging in 26 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of the study is to identify the sites of modification when fibronectin reacts with glycolaldehyde or methylglyoxal as a model system for aging of Bruch's membrane." | 7.83 | The glycation of fibronectin by glycolaldehyde and methylglyoxal as a model for aging in Bruch's membrane. ( Gaillard, ER; Thao, MT, 2016) |
| " The purpose of this study was to investigate modifications from glycolaldehyde and A2E, which are present in the retinal pigment epithelium (RPE), on the membrane like protein fragment, laminin, as a model for aging of Bruch's membrane in age related eye diseases." | 7.75 | Modifications to the basement membrane protein laminin using glycolaldehyde and A2E: a model for aging in Bruch's membrane. ( Dillon, J; Gaillard, ER; Murdaugh, LS, 2009) |
| "The purpose of the study is to identify the sites of modification when fibronectin reacts with glycolaldehyde or methylglyoxal as a model system for aging of Bruch's membrane." | 3.83 | The glycation of fibronectin by glycolaldehyde and methylglyoxal as a model for aging in Bruch's membrane. ( Gaillard, ER; Thao, MT, 2016) |
| " The purpose of this study was to investigate modifications from glycolaldehyde and A2E, which are present in the retinal pigment epithelium (RPE), on the membrane like protein fragment, laminin, as a model for aging of Bruch's membrane in age related eye diseases." | 3.75 | Modifications to the basement membrane protein laminin using glycolaldehyde and A2E: a model for aging in Bruch's membrane. ( Dillon, J; Gaillard, ER; Murdaugh, LS, 2009) |
| " The reactivity of these groups not only has an important role in the maintenance of mechanical strength in collagen fibrils, but can also manifest pathologically in the cases of aging, diabetes (reactivity with a variety of sugars) and alcoholism (reactivity with acetaldehyde)." | 3.69 | The chemical reactivity and structure of collagen studied by neutron diffraction. ( Miller, A; Wess, L; Wess, TJ, 1996) |
| "The frequent use of alcohol (ethanol) together with prescription drugs gives any described pharmacokinetic interaction significant clinical implications." | 2.40 | Pharmacokinetic interactions between alcohol and other drugs. ( Fraser, AG, 1997) |
| "Thus acetaldehyde was more stimulatory in young and more inhibitory in the adult brain areas tested, which could explain its stimulating nicotine reward only in young animals." | 1.35 | The effects of acetaldehyde on nicotine-induced transmitter levels in young and adult brain areas. ( Chakraborty, G; Fallon, S; Lajtha, A; Sershen, H; Shearman, E; Smiley, J, 2009) |
| "25 kg (designated mature) body weight (BW) were dosed acutely with alcohol (75 mmol/kg BW; intraperitoneal [IP], 2." | 1.31 | Effect of acute and chronic alcohol treatment and their superimposition on lysosomal, cytoplasmic, and proteosomal protease activities in rat skeletal muscle in vivo. ( Ahmed, S; Donohue, TM; Koll, M; Mantle, D; Palmer, TN; Peters, TJ; Preedy, VR; Seltz, HK; Simanowski, UA, 2002) |
| "Glycolaldehyde was used to modify bovine serum albumin and HPLC analysis was used to measure pentosidine formation as an indicator of AGE formation." | 1.30 | Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye. ( Aotaki-Keen, A; Farboud, B; Handa, JT; Hjelmeland, LM; Miyata, T, 1999) |
| " In 8-week-old animals, however, acetaldehyde or ethanol given with MPTP decreased striatal DA content to about 10% of controls, whereas the depletion was to 43% of controls when MPTP was given alone." | 1.28 | MPTP treatment combined with ethanol or acetaldehyde selectively destroys dopaminergic neurons in mouse substantia nigra. ( Corsini, GU; di Porzio, U; Johannessen, JN; Kopin, IJ; Schinelli, S; Zuddas, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 9 (34.62) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thao, MT | 1 |
| Gaillard, ER | 2 |
| Murdaugh, LS | 1 |
| Dillon, J | 1 |
| Sershen, H | 1 |
| Shearman, E | 1 |
| Fallon, S | 1 |
| Chakraborty, G | 1 |
| Smiley, J | 1 |
| Lajtha, A | 1 |
| Garaycoechea, JI | 1 |
| Crossan, GP | 1 |
| Langevin, F | 1 |
| Daly, M | 1 |
| Arends, MJ | 1 |
| Patel, KJ | 1 |
| Nishimura, FT | 1 |
| Fukunaga, T | 1 |
| Yokomukai, Y | 1 |
| Kajiura, H | 1 |
| Ono, T | 1 |
| Nishijo, H | 1 |
| Akimoto, T | 1 |
| Cho, S | 1 |
| Yoshida, H | 1 |
| Furuta, H | 1 |
| Esashi, Y | 1 |
| Kim, JM | 1 |
| Stewart, R | 1 |
| Shin, IS | 1 |
| Jung, JS | 1 |
| Yoon, JS | 1 |
| Belluzzi, JD | 2 |
| Wang, R | 1 |
| Leslie, FM | 2 |
| Poon, HF | 1 |
| Farr, SA | 1 |
| Banks, WA | 1 |
| Pierce, WM | 1 |
| Klein, JB | 1 |
| Morley, JE | 1 |
| Butterfield, DA | 1 |
| Park, MK | 1 |
| Han, SH | 1 |
| Cao, J | 1 |
| Chrostek, L | 1 |
| Cylwik, B | 1 |
| Szmitkowski, M | 1 |
| Messiha, FS | 1 |
| Simanowski, UA | 2 |
| Suter, P | 1 |
| Russell, RM | 1 |
| Heller, M | 1 |
| Waldherr, R | 1 |
| Ward, R | 1 |
| Peters, TJ | 2 |
| Smith, D | 1 |
| Seitz, HK | 1 |
| Tan, XX | 1 |
| Castoldi, AF | 1 |
| Manzo, L | 1 |
| Costa, LG | 1 |
| Devi, GU | 2 |
| Indira, K | 2 |
| Babu, GR | 2 |
| Chetty, CS | 2 |
| Wess, TJ | 1 |
| Wess, L | 1 |
| Miller, A | 1 |
| Fraser, AG | 1 |
| Farboud, B | 1 |
| Aotaki-Keen, A | 1 |
| Miyata, T | 1 |
| Hjelmeland, LM | 1 |
| Handa, JT | 1 |
| Koll, M | 1 |
| Ahmed, S | 1 |
| Mantle, D | 1 |
| Donohue, TM | 1 |
| Palmer, TN | 1 |
| Seltz, HK | 1 |
| Preedy, VR | 1 |
| Tesco, G | 1 |
| Latorraca, S | 1 |
| Piersanti, P | 1 |
| Piacentini, S | 1 |
| Amaducci, L | 1 |
| Sorbi, S | 1 |
| Rikans, LE | 1 |
| Snowden, CD | 1 |
| Moore, DR | 1 |
| Zuddas, A | 1 |
| Corsini, GU | 1 |
| Schinelli, S | 1 |
| Johannessen, JN | 1 |
| di Porzio, U | 1 |
| Kopin, IJ | 1 |
| Hesselbrock, VM | 1 |
| Shaskan, EG | 1 |
| Crompton, M | 1 |
| Laties, GG | 1 |
| Wilson, AS | 1 |
| Barboriak, JJ | 1 |
| Kass, WA | 1 |
2 reviews available for acetaldehyde and Aging
| Article | Year |
|---|---|
[Age and ethanol metabolism].
Topics: Acetaldehyde; Aged; Aging; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Central Nervous | 2006 |
Pharmacokinetic interactions between alcohol and other drugs.
Topics: Acetaldehyde; Aging; Alcohol Dehydrogenase; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroida | 1997 |
24 other studies available for acetaldehyde and Aging
| Article | Year |
|---|---|
The glycation of fibronectin by glycolaldehyde and methylglyoxal as a model for aging in Bruch's membrane.
Topics: Acetaldehyde; Aging; Bruch Membrane; Fibronectins; Humans; Models, Biological; Pyruvaldehyde | 2016 |
Modifications to the basement membrane protein laminin using glycolaldehyde and A2E: a model for aging in Bruch's membrane.
Topics: Acetaldehyde; Aging; Bruch Membrane; Eye Proteins; Glycation End Products, Advanced; Humans; Laminin | 2009 |
The effects of acetaldehyde on nicotine-induced transmitter levels in young and adult brain areas.
Topics: Acetaldehyde; Aging; Animals; Brain; Catheterization; Central Nervous System Agents; Dopamine; Hippo | 2009 |
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.
Topics: Acetaldehyde; Aging; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Anima | 2012 |
Age-dependent changes in electroencephalographic responses to alcohol consumption in subjects with aldehyde dehydrogenase-2 genetic variations.
Topics: Acetaldehyde; Adult; Aging; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitoch | 2003 |
Involvement of acetaldehyde in seed deterioration of some recalcitrant woody species through the acceleration of aerobic respiration.
Topics: Acetaldehyde; Aerobiosis; Aging; Cell Survival; Cellular Senescence; Enzymes; Oxidative Phosphorylat | 2004 |
Assessment of association between mitochondrial aldehyde dehydrogenase polymorphism and Alzheimer's disease in an older Korean population.
Topics: Acetaldehyde; Age Factors; Aged; Aging; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehy | 2004 |
Acetaldehyde enhances acquisition of nicotine self-administration in adolescent rats.
Topics: Acetaldehyde; Adolescent; Age Factors; Aging; Animals; Brain; Brain Chemistry; Cocaine; Disease Mode | 2005 |
Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein.
Topics: Acetaldehyde; Aging; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Brain; Electrophore | 2005 |
Age, sex and early environment contribute to individual differences in nicotine/acetaldehyde-induced behavioral and endocrine responses in rats.
Topics: Acetaldehyde; Aging; Animals; Animals, Newborn; Behavior, Animal; Catheterization, Peripheral; Corti | 2007 |
Development and kinetic aspects of rat eye aldehyde dehydrogenase.
Topics: Acetaldehyde; Aging; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Eye; Female; Kinetic | 1982 |
Enhancement of ethanol induced rectal mucosal hyper regeneration with age in F344 rats.
Topics: Acetaldehyde; Aging; Animals; Cell Division; Ethanol; Intestinal Mucosa; Male; Rats; Rats, Inbred F3 | 1994 |
Interaction of ethanol with muscarinic receptor-stimulated phosphoinositide metabolism during the brain growth spurt in the rat: role of acetaldehyde.
Topics: 1-Propanol; Acetaldehyde; Aging; Aldehydes; Animals; Brain; Carbachol; Cerebellum; Cerebral Cortex; | 1993 |
Age-related metabolic effects of acetaldehyde on rats with reference to detoxification enzymes and sulfhydryl groups.
Topics: Acetaldehyde; Aging; Animals; Female; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase | 1996 |
Effect of acetaldehyde on oxidoreductases in tissues of rats at different ages.
Topics: Acetaldehyde; Aging; Animals; Female; Oxidoreductases; Rats; Rats, Wistar | 1996 |
The chemical reactivity and structure of collagen studied by neutron diffraction.
Topics: Acetaldehyde; Aging; Alcoholism; Animals; Collagen; Crystallography; Deuterium; Diabetes Mellitus, T | 1996 |
Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.
Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Aging; Animals; Antibodies; Antibody Specificity; Argi | 1999 |
Effect of acute and chronic alcohol treatment and their superimposition on lysosomal, cytoplasmic, and proteosomal protease activities in rat skeletal muscle in vivo.
Topics: Acetaldehyde; Aging; Animals; Cysteine Endopeptidases; Cytoplasm; Drug Administration Schedule; Endo | 2002 |
Alzheimer skin fibroblasts show increased susceptibility to free radicals.
Topics: Acetaldehyde; Aging; Alzheimer Disease; Cell Line; Cell Survival; Fibroblasts; Free Radical Scavenge | 1992 |
Influence of aging on ethanol and acetaldehyde oxidation in female rat liver.
Topics: Acetaldehyde; Aging; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Animals | 1990 |
MPTP treatment combined with ethanol or acetaldehyde selectively destroys dopaminergic neurons in mouse substantia nigra.
Topics: Acetaldehyde; Aging; Animals; Dopamine; Drug Interactions; Ethanol; Male; Mice; Mice, Inbred C57BL; | 1989 |
Endogenous breath acetaldehyde levels among alcoholic and non-alcoholic probands: effect of alcohol use and smoking.
Topics: Acetaldehyde; Adolescent; Adult; Aged; Aging; Alcohol Drinking; Alcoholism; Breath Tests; Female; Hu | 1985 |
The regulatory function of potato pyruvate dehydrogenase.
Topics: Acetaldehyde; Adenine Nucleotides; Adenosine Triphosphate; Aerobiosis; Aging; Anaerobiosis; Buffers; | 1971 |
Effects of alcoholic beverages and congeners on psychomotor skills in old and young subjects.
Topics: Acetaldehyde; Acetates; Adult; Aged; Aging; Alcoholic Beverages; Alcoholic Intoxication; Alcohols; F | 1970 |