acetaldehyde has been researched along with Acute Liver Injury, Drug-Induced in 31 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The equimolar produced metabolite DCCTX was chosen to reflect chloroacetaldehyde (CAA, a toxic metabolite of CTX) production in rats." | 1.48 | Schisandra chinensis extract decreases chloroacetaldehyde production in rats and attenuates cyclophosphamide toxicity in liver, kidney and brain. ( Chen, L; Chen, W; Feng, G; Gao, S; Yin, J; Zhai, J; Zhang, F, 2018) |
| "Vinyl chloride (VC) is a ubiquitous environmental contaminant for which human risk is incompletely understood." | 1.43 | Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice. ( Anders, LC; Anwar-Mohamed, A; Arteel, GE; Beier, JI; Bushau, AM; Cave, M; Douglas, AN; Falkner, KC; Hill, BG; Lang, AL; McClain, CJ; Warner, NL, 2016) |
| "Unlike the action of alcohol treatment on fatty liver, BFSP administration attenuated lipid droplet accumulation in hepatocytes." | 1.38 | Hepatoprotective effects on alcoholic liver disease of fermented silkworms with Bacillus subtilis and Aspergillus kawachii. ( Cha, JY; Cho, YS; Kim, YS; Moon, HI, 2012) |
| "Phenobarbital pretreatment of the rats did not affect any of these kinetic parameters." | 1.28 | Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol. ( Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M, 1992) |
| " The enzymes involved in the toxic metabolic pathway have been investigated in this study." | 1.28 | Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol. ( Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (41.94) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 8 (25.81) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Song, XY | 1 |
| Liu, PC | 1 |
| Liu, WW | 1 |
| Hayashi, T | 1 |
| Mizuno, K | 1 |
| Hattori, S | 1 |
| Fujisaki, H | 1 |
| Ikejima, T | 1 |
| Park, SH | 1 |
| Seo, W | 1 |
| Xu, MJ | 1 |
| Mackowiak, B | 1 |
| Lin, Y | 1 |
| He, Y | 1 |
| Fu, Y | 1 |
| Hwang, S | 1 |
| Kim, SJ | 1 |
| Guan, Y | 1 |
| Feng, D | 1 |
| Yu, L | 1 |
| Lehner, R | 1 |
| Liangpunsakul, S | 1 |
| Gao, B | 2 |
| Zhai, J | 1 |
| Zhang, F | 1 |
| Gao, S | 1 |
| Chen, L | 1 |
| Feng, G | 1 |
| Yin, J | 1 |
| Chen, W | 1 |
| Wei, J | 1 |
| Huang, Q | 1 |
| Huang, R | 1 |
| Chen, Y | 1 |
| Lv, S | 1 |
| Wei, L | 1 |
| Liang, C | 1 |
| Liang, S | 1 |
| Zhuo, L | 1 |
| Lin, X | 1 |
| Kwon, HJ | 1 |
| Won, YS | 1 |
| Park, O | 1 |
| Chang, B | 1 |
| Duryee, MJ | 1 |
| Thiele, GE | 1 |
| Matsumoto, A | 1 |
| Singh, S | 1 |
| Abdelmegeed, MA | 1 |
| Song, BJ | 2 |
| Kawamoto, T | 1 |
| Vasiliou, V | 1 |
| Thiele, GM | 1 |
| Xie, W | 1 |
| Sun, J | 1 |
| Zhang, X | 1 |
| Melzig, MF | 1 |
| Anders, LC | 1 |
| Lang, AL | 1 |
| Anwar-Mohamed, A | 1 |
| Douglas, AN | 1 |
| Bushau, AM | 1 |
| Falkner, KC | 1 |
| Hill, BG | 1 |
| Warner, NL | 1 |
| Arteel, GE | 1 |
| Cave, M | 1 |
| McClain, CJ | 1 |
| Beier, JI | 1 |
| Zhang, YJ | 1 |
| Wang, F | 1 |
| Zhou, Y | 1 |
| Li, Y | 1 |
| Zhou, T | 1 |
| Zheng, J | 1 |
| Zhang, JJ | 1 |
| Li, S | 1 |
| Xu, DP | 1 |
| Li, HB | 1 |
| Upreti, VV | 1 |
| Eddington, ND | 1 |
| Moon, KH | 1 |
| Lee, IJ | 1 |
| Cha, JY | 1 |
| Kim, YS | 1 |
| Moon, HI | 1 |
| Cho, YS | 1 |
| Guo, Y | 1 |
| Wu, XQ | 1 |
| Zhang, C | 1 |
| Liao, ZX | 1 |
| Wu, Y | 1 |
| Wang, H | 1 |
| Nakamura, Y | 1 |
| Yokoyama, H | 2 |
| Higuchi, S | 1 |
| Hara, S | 1 |
| Kato, S | 2 |
| Ishii, H | 2 |
| Vassallo, JD | 1 |
| Hicks, SM | 1 |
| Daston, GP | 1 |
| Lehman-McKeeman, LD | 1 |
| Nagata, S | 1 |
| Kamegaya, K | 1 |
| Tsuchiya, M | 1 |
| Matysiak-Budnik, T | 1 |
| Jokelainen, K | 1 |
| Kärkkäinen, P | 1 |
| Mäkisalo, H | 1 |
| Ohisalo, J | 1 |
| Salaspuro, M | 1 |
| Löf, K | 1 |
| Lindros, K | 1 |
| Seppa, K | 1 |
| Fukunaga, T | 1 |
| Badger, T | 1 |
| Ronis, M | 1 |
| Sillanaukee, P | 1 |
| Moura, D | 1 |
| Azevedo, I | 1 |
| Osswald, W | 1 |
| Leeve, CM | 1 |
| Zetterman, R | 1 |
| Taskaev, II | 1 |
| Braun, R | 1 |
| Greeff, U | 1 |
| Netter, KJ | 1 |
| Macdonald, CM | 1 |
| Dow, J | 1 |
| Moore, MR | 1 |
| Bossone, CM | 1 |
| Zetterman, RK | 1 |
| Leevy, CM | 2 |
| Maling, HM | 1 |
| Stripp, B | 1 |
| Sipes, IG | 1 |
| Highman, B | 1 |
| Saul, W | 1 |
| Williams, MA | 1 |
| Kaminsky, LS | 1 |
| Fraser, JM | 1 |
| Seaman, M | 1 |
| Dunbar, D | 1 |
| Trudell, JR | 1 |
| Ardies, CM | 1 |
| Anderson, WR | 1 |
| Hobara, N | 1 |
| Freundt, KJ | 1 |
| Lieberwirth, H | 1 |
| Myerson, RM | 1 |
| Sorrell, MF | 1 |
| Gincheva, NA | 1 |
2 reviews available for acetaldehyde and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Immunologic reactivity and alcoholic liver disease.
Topics: Acetaldehyde; Alcoholism; Antigen-Antibody Reactions; B-Lymphocytes; Caffeine; Chemical and Drug Ind | 1975 |
Metabolic aspects of alcohol and their biological significance.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Bone and Bones; Cardiomyopathies; Catala | 1973 |
29 other studies available for acetaldehyde and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Protective effects of silibinin against ethanol- or acetaldehyde-caused damage in liver cell lines involve the repression of mitochondrial fission.
Topics: Acetaldehyde; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Chemical and Drug Induced Liver I | 2022 |
Ethanol and its Nonoxidative Metabolites Promote Acute Liver Injury by Inducing ER Stress, Adipocyte Death, and Lipolysis.
Topics: Acetaldehyde; Adipocytes; Animals; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum Str | 2023 |
Schisandra chinensis extract decreases chloroacetaldehyde production in rats and attenuates cyclophosphamide toxicity in liver, kidney and brain.
Topics: Acetaldehyde; Animals; Antineoplastic Agents, Alkylating; Area Under Curve; Brain; Chemical and Drug | 2018 |
Asiatic acid from Potentilla chinensis attenuate ethanol-induced hepatic injury via suppression of oxidative stress and Kupffer cell activation.
Topics: Acetaldehyde; Animals; Catalase; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; En | 2013 |
Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitoc | 2014 |
Necrosis factor-alpha (TNF-alpha) response in human hepatoma HepG2 cells treated with hepatotoxic agents.
Topics: Acetaldehyde; Acetaminophen; Cell Line; Cell Survival; Central Nervous System Depressants; Chemical | 2014 |
Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice.
Topics: Acetaldehyde; AMP-Activated Protein Kinases; Animals; Carbohydrate Metabolism; Chemical and Drug Ind | 2016 |
Effects of 20 Selected Fruits on Ethanol Metabolism: Potential Health Benefits and Harmful Impacts.
Topics: Acetaldehyde; Alanine Transaminase; Alcohol Dehydrogenase; Alcoholic Intoxication; Aldehyde Oxidored | 2016 |
Drug interaction between ethanol and 3,4-methylenedioxymethamphetamine ("ecstasy").
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitoc | 2009 |
Hepatoprotective effects on alcoholic liver disease of fermented silkworms with Bacillus subtilis and Aspergillus kawachii.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Animals; Antioxidants; Aspartate Amin | 2012 |
Protective effect of sodium ferulate on acetaldehyde-treated precision-cut rat liver slices.
Topics: Acetaldehyde; Actins; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Collagen; Couma | 2012 |
Acetaldehyde accumulation suppresses Kupffer cell release of TNF-Alpha and modifies acute hepatic inflammation in rats.
Topics: Acetaldehyde; Animals; Blotting, Northern; Cell Culture Techniques; Chemical and Drug Induced Liver | 2004 |
Metabolic detoxification determines species differences in coumarin-induced hepatotoxicity.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Oxidase; Animals; Anticoagulants; Chemical and Drug I | 2004 |
Experimental hepatitis induced by ethanol after immunization with acetaldehyde adducts.
Topics: Acetaldehyde; Animals; Antibodies; Chemical and Drug Induced Liver Injury; Ethanol; Female; Guinea P | 1993 |
Hepatotoxicity and absorption of extrahepatic acetaldehyde in rats.
Topics: Absorption; Acetaldehyde; Animals; Chemical and Drug Induced Liver Injury; Colon; Dose-Response Rela | 1996 |
The effect of ethanol or hepatotoxin exposure on rat transferrin desialylation.
Topics: Acetaldehyde; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethan | 1996 |
Hepatotoxicity of the condensation product of adrenaline with acetaldehyde.
Topics: Acetaldehyde; Animals; Chemical and Drug Induced Liver Injury; Epinephrine; Liver; Liver Diseases; M | 1977 |
Alcoholic hepatitis, cirrhosis, and immunologic reactivity.
Topics: Acetaldehyde; Alcoholism; B-Lymphocytes; Cells, Cultured; Chemical and Drug Induced Liver Injury; Co | 1975 |
[Histochemical and cytologic changes in the liver in experimental poisoning and subsequent pregnancy].
Topics: Acetaldehyde; Animals; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Chronic Disease; Fem | 1979 |
Liver injury by the false morel poison gyromitrin.
Topics: Acetaldehyde; Aminopyrine; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme | 1979 |
A possible protective role for sulphydryl compounds in acute alcoholic liver injury.
Topics: Acetaldehyde; Alcoholic Intoxication; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dos | 1977 |
The liver: a pharmacologic perspective.
Topics: Acetaldehyde; Alcoholism; Chemical and Drug Induced Liver Injury; Diuretics; Drug-Related Side Effec | 1977 |
Enhanced hepatotoxicity of carbon tetrachloride, thioacetamide, and dimethylnitrosamine by pretreatment of rats with ethanol and some comparisons with potentiation by isopropanol.
Topics: 1-Propanol; Acetaldehyde; Acetamides; Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; | 1975 |
Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol.
Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Biotransformation; Chemical and Drug Induced Liver In | 1992 |
The effect of alcohol and anesthetic metabolites on cell membranes. A possible direct immune mechanism.
Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Cell Membrane; Chemical and Drug Induced Live | 1991 |
Acetaldehyde metabolism in liver injury.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Chemical and Drug Induced Liver Injury; Ethanol; Live | 1985 |
Proceedings: Influence of inhaled carbon disulphide on acetaldehyde production and liver function in alcoholized man.
Topics: Acetaldehyde; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Glucose; Bl | 1974 |
Lymphocyte transformation and alcoholic liver injury.
Topics: Acetaldehyde; Alcoholism; Cells, Cultured; Chemical and Drug Induced Liver Injury; DNA; Ethanol; Fat | 1972 |
[Toxicological characteristics of the products of the thermal destruction of polyethylene-terephthalate].
Topics: Acetaldehyde; Air Pollution; Animals; Body Temperature; Body Weight; Chemical and Drug Induced Liver | 1971 |