acetaldehyde has been researched along with Abnormalities, Drug-Induced in 17 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disulfiram, in 1 mg and 10 mg oral doses, was given to inbred C3H mice prior to and for the duration of pregnancy." | 3.67 | The effects of disulfiram on the experimental C3H mouse embryo. ( Folb, PI; Thompson, PA, 1985) |
| "The proximate teratogen of the fetal alcohol syndrome is unknown." | 1.27 | Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde. ( Blakley, PM; Scott, WJ, 1984) |
| "Acetaldehyde-treated females had more resorptions both at mid-gestation and at term, though no significant difference in maternal weight gain was observed." | 1.26 | The teratogenic effect of acetaldehyde: implications for the study of the fetal alcohol syndrome. ( Kaufman, MH; O'Shea, KS, 1979) |
| "The symptoms of the fetal alcohol syndrome and their frequency of appearance are described based on 41 reports in the literature and on own observations." | 1.26 | The fetal alcohol syndrome: symptoms and pathogenesis. ( Igali, S; Imrei, J; Kardos, G; Leisztner, L; Osztovics, M; Szaszovszky, E; Véghelyi, PV, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (76.47) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blakley, PM | 1 |
| Scott, WJ | 1 |
| Beck, F | 1 |
| Huxham, IM | 1 |
| Gulamhusein, AP | 1 |
| Sreenathan, RN | 2 |
| Padmanabhan, R | 2 |
| Singh, S | 2 |
| Skakun, NP | 1 |
| Thompson, PA | 2 |
| Folb, PI | 2 |
| Majewski, F | 1 |
| Nesterick, CA | 1 |
| Rahwan, RG | 1 |
| Skosyreva, AM | 1 |
| Cooper, P | 1 |
| Johnson, PD | 1 |
| Dawson, BV | 1 |
| Goldberg, SJ | 1 |
| Menegola, E | 2 |
| Broccia, ML | 2 |
| Di Renzo, F | 1 |
| Giavini, E | 2 |
| Klug, S | 1 |
| Merker, HJ | 1 |
| Jäckh, R | 1 |
| O'Shea, KS | 1 |
| Kaufman, MH | 1 |
| Véghelyi, PV | 1 |
| Osztovics, M | 1 |
| Kardos, G | 1 |
| Leisztner, L | 1 |
| Szaszovszky, E | 1 |
| Igali, S | 1 |
| Imrei, J | 1 |
| Prati, M | 1 |
| Bellomo, D | 1 |
1 review available for acetaldehyde and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Kinetics and teratogenic action of ethyl alcohol].
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Alcohol Oxidoreductases; Animals; Biotransformatio | 1981 |
16 other studies available for acetaldehyde and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; | 1984 |
Growth of rat embryos in the serum of alcohol drinkers.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Alcohol Drinking; Animals; Blood; Ethanol; Female; | 1984 |
Structural changes of placenta following maternal administration of acetaldehyde in rat.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Female; Placenta; Pregnancy; Rats; Rats, Inbred | 1984 |
Teratogenic effects of acetaldehyde in the rat.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Bone and Bones; Dose-Response Relationship, Drug | 1982 |
An in vitro model of alcohol and acetaldehyde teratogenicity.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Brain; DNA; Embryo, Mammalian; Ethanol; Female; | 1982 |
Alcohol embryopathy: some facts and speculations about pathogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcoholic Beverages; Alcoholism; Brain; Child; Child, Pre | 1981 |
Absence of a role for salsolinol in the mechanism of ethanol teratogenicity.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcoholism; Animals; Animals, Newborn; Ethanol; Female; F | 1981 |
[Comparative study of the direct embryotoxic effect of alcohol and its metabolite acetaldehyde during organogenesis].
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Dose-Response Relationship, Drug; Embryo, Mammal | 1982 |
Alcohol and pregnancy--part 1: animal data.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcohol Drinking; Animals; Brain; Ethanol; Female; Fetal | 1980 |
Cardiac teratogenicity of trichloroethylene metabolites.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Acetates; Animals; Chloral Hydrate; Cystine; Dichloroethy | 1998 |
Acetaldehyde in vitro exposure and apoptosis: a possible mechanism of teratogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Apoptosis; Branchial Region; Cell Death; Embryo, | 2001 |
Effects of ethylene glycol and metabolites on in vitro development of rat embryos during organogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animal Testing Alternatives; Animals; Dose-Response Relat | 2001 |
The teratogenic effect of acetaldehyde: implications for the study of the fetal alcohol syndrome.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Body Weight; Central Nervous System; Dose-Respon | 1979 |
The fetal alcohol syndrome: symptoms and pathogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Aldehyde Oxidoreductases; Animals; Child, Preschoo | 1978 |
Effects of ethanol and acetaldehyde on rat embryos developing in vitro.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Culture Techniques; Dose-Response Relationship, | 1992 |
The effects of disulfiram on the experimental C3H mouse embryo.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Disulfiram; DNA; Embryo, Mammalian; Female; Fetu | 1985 |