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acetaldehyde and Abnormalities, Drug-Induced

acetaldehyde has been researched along with Abnormalities, Drug-Induced in 17 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"Disulfiram, in 1 mg and 10 mg oral doses, was given to inbred C3H mice prior to and for the duration of pregnancy."3.67The effects of disulfiram on the experimental C3H mouse embryo. ( Folb, PI; Thompson, PA, 1985)
"The proximate teratogen of the fetal alcohol syndrome is unknown."1.27Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde. ( Blakley, PM; Scott, WJ, 1984)
"Acetaldehyde-treated females had more resorptions both at mid-gestation and at term, though no significant difference in maternal weight gain was observed."1.26The teratogenic effect of acetaldehyde: implications for the study of the fetal alcohol syndrome. ( Kaufman, MH; O'Shea, KS, 1979)
"The symptoms of the fetal alcohol syndrome and their frequency of appearance are described based on 41 reports in the literature and on own observations."1.26The fetal alcohol syndrome: symptoms and pathogenesis. ( Igali, S; Imrei, J; Kardos, G; Leisztner, L; Osztovics, M; Szaszovszky, E; Véghelyi, PV, 1978)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199013 (76.47)18.7374
1990's2 (11.76)18.2507
2000's2 (11.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blakley, PM1
Scott, WJ1
Beck, F1
Huxham, IM1
Gulamhusein, AP1
Sreenathan, RN2
Padmanabhan, R2
Singh, S2
Skakun, NP1
Thompson, PA2
Folb, PI2
Majewski, F1
Nesterick, CA1
Rahwan, RG1
Skosyreva, AM1
Cooper, P1
Johnson, PD1
Dawson, BV1
Goldberg, SJ1
Menegola, E2
Broccia, ML2
Di Renzo, F1
Giavini, E2
Klug, S1
Merker, HJ1
Jäckh, R1
O'Shea, KS1
Kaufman, MH1
Véghelyi, PV1
Osztovics, M1
Kardos, G1
Leisztner, L1
Szaszovszky, E1
Igali, S1
Imrei, J1
Prati, M1
Bellomo, D1

Reviews

1 review available for acetaldehyde and Abnormalities, Drug-Induced

ArticleYear
[Kinetics and teratogenic action of ethyl alcohol].
    Akusherstvo i ginekologiia, 1981, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Alcohol Oxidoreductases; Animals; Biotransformatio

1981

Other Studies

16 other studies available for acetaldehyde and Abnormalities, Drug-Induced

ArticleYear
Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde.
    Toxicology and applied pharmacology, 1984, Volume: 72, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals;

1984
Growth of rat embryos in the serum of alcohol drinkers.
    Ciba Foundation symposium, 1984, Volume: 105

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Alcohol Drinking; Animals; Blood; Ethanol; Female;

1984
Structural changes of placenta following maternal administration of acetaldehyde in rat.
    Zeitschrift fur mikroskopisch-anatomische Forschung, 1984, Volume: 98, Issue:4

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Female; Placenta; Pregnancy; Rats; Rats, Inbred

1984
Teratogenic effects of acetaldehyde in the rat.
    Drug and alcohol dependence, 1982, Volume: 9, Issue:4

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Bone and Bones; Dose-Response Relationship, Drug

1982
An in vitro model of alcohol and acetaldehyde teratogenicity.
    Journal of applied toxicology : JAT, 1982, Volume: 2, Issue:4

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Brain; DNA; Embryo, Mammalian; Ethanol; Female;

1982
Alcohol embryopathy: some facts and speculations about pathogenesis.
    Neurobehavioral toxicology and teratology, 1981,Summer, Volume: 3, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcoholic Beverages; Alcoholism; Brain; Child; Child, Pre

1981
Absence of a role for salsolinol in the mechanism of ethanol teratogenicity.
    Developmental pharmacology and therapeutics, 1981, Volume: 3, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcoholism; Animals; Animals, Newborn; Ethanol; Female; F

1981
[Comparative study of the direct embryotoxic effect of alcohol and its metabolite acetaldehyde during organogenesis].
    Akusherstvo i ginekologiia, 1982, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Dose-Response Relationship, Drug; Embryo, Mammal

1982
Alcohol and pregnancy--part 1: animal data.
    Food and cosmetics toxicology, 1980, Volume: 18, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcohol Drinking; Animals; Brain; Ethanol; Female; Fetal

1980
Cardiac teratogenicity of trichloroethylene metabolites.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Acetates; Animals; Chloral Hydrate; Cystine; Dichloroethy

1998
Acetaldehyde in vitro exposure and apoptosis: a possible mechanism of teratogenesis.
    Alcohol (Fayetteville, N.Y.), 2001, Volume: 23, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Apoptosis; Branchial Region; Cell Death; Embryo,

2001
Effects of ethylene glycol and metabolites on in vitro development of rat embryos during organogenesis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2001, Volume: 15, Issue:6

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animal Testing Alternatives; Animals; Dose-Response Relat

2001
The teratogenic effect of acetaldehyde: implications for the study of the fetal alcohol syndrome.
    Journal of anatomy, 1979, Volume: 128, Issue:Pt 1

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Body Weight; Central Nervous System; Dose-Respon

1979
The fetal alcohol syndrome: symptoms and pathogenesis.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1978, Volume: 19, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Adult; Aldehyde Oxidoreductases; Animals; Child, Preschoo

1978
Effects of ethanol and acetaldehyde on rat embryos developing in vitro.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1992, Volume: 28A, Issue:3 Pt 1

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Culture Techniques; Dose-Response Relationship,

1992
The effects of disulfiram on the experimental C3H mouse embryo.
    Journal of applied toxicology : JAT, 1985, Volume: 5, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Disulfiram; DNA; Embryo, Mammalian; Female; Fetu

1985