acetaldehyde has been researched along with Abnormalities, Autosome in 17 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetaldehyde (AA) was tested along with two other crosslinking agents: formaldehyde (FA), an inducer of DNA-protein crosslinks (DPCs) and mitomycin C (MMC), an inducer of interstrand crosslinks (ICLs), to find out whether the mechanism of action of AA resembles more MMC or FA." | 1.35 | Relationship between DNA lesions, DNA repair and chromosomal damage induced by acetaldehyde. ( Kobos, K; Lorenti Garcia, C; Mechilli, M; Palitti, F; Proietti De Santis, L; Schinoppi, A, 2009) |
| "Induction of chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) by acetaldehyde (AA) was evaluated in parental and different DNA repair-deficient Chinese hamster ovary (CHO) cell lines to elucidate the mechanisms involved in the protection against AA-induced chromosome damage." | 1.35 | DNA repair deficiency and acetaldehyde-induced chromosomal alterations in CHO cells. ( Kobos, K; Mechilli, M; Natarajan, AT; Palitti, F; Schinoppi, A, 2008) |
| "Posttreatment with acetaldehyde, the major metabolite of ethanol, also potentiated the chromosome aberrations induced by UV, MMS, MMC or BLM." | 1.28 | Ethanol and acetaldehyde potentiate the clastogenicity of ultraviolet light, methyl methanesulfonate, mitomycin C and bleomycin in Chinese hamster ovary cells. ( Ho, IC; Lee, TC; Lin, YC, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (58.82) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Natarajan, AT | 4 |
| Palitti, F | 3 |
| Lorenti Garcia, C | 1 |
| Mechilli, M | 2 |
| Proietti De Santis, L | 1 |
| Schinoppi, A | 2 |
| Kobos, K | 2 |
| Kayani, MA | 1 |
| Parry, JM | 1 |
| Bird, RP | 1 |
| Draper, HH | 1 |
| Basrur, PK | 1 |
| Korte, A | 1 |
| Obe, G | 3 |
| Ingwersen, I | 1 |
| Rückert, G | 1 |
| Chiewchanwit, T | 1 |
| Au, WW | 3 |
| Morris, DL | 1 |
| Legator, MS | 1 |
| Ratanavalachai, TC | 1 |
| Ristow, H | 1 |
| Meyers, M | 1 |
| Hertog, AD | 1 |
| Il'inskikh, NN | 1 |
| Il'inskikh, IN | 1 |
| Makarov, LN | 1 |
| Chernoskutova, SA | 1 |
| Lin, YC | 1 |
| Ho, IC | 1 |
| Lee, TC | 1 |
| Cortés, F | 1 |
| Mateos, S | 1 |
| Ortiz, T | 1 |
| Piñero, J | 1 |
| Lambert, B | 1 |
| He, SM | 1 |
| Norppa, H | 1 |
| Tursi, F | 1 |
| Pfäffli, P | 1 |
| Mäki-Paakkanen, J | 1 |
| Järventaus, H | 1 |
2 reviews available for acetaldehyde and Abnormalities, Autosome
| Article | Year |
|---|---|
DNA repair and chromosomal alterations.
Topics: Acetaldehyde; Animals; CHO Cells; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Breaks, Double | 2008 |
Mutagenic, cancerogenic and teratogenic effects of alcohol.
Topics: Acetaldehyde; Adult; Alcoholism; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; Drosophi | 1979 |
15 other studies available for acetaldehyde and Abnormalities, Autosome
| Article | Year |
|---|---|
Relationship between DNA lesions, DNA repair and chromosomal damage induced by acetaldehyde.
Topics: Acetaldehyde; Animals; Cell Division; CHO Cells; Chromosome Aberrations; Chromosomes, Mammalian; Cri | 2009 |
The in vitro genotoxicity of ethanol and acetaldehyde.
Topics: Acetaldehyde; Aneuploidy; Apoptosis; Cell Line; Cell Proliferation; Cell Survival; Central Nervous S | 2010 |
DNA repair deficiency and acetaldehyde-induced chromosomal alterations in CHO cells.
Topics: Acetaldehyde; Animals; CHO Cells; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Repair; Mutage | 2008 |
Effect of malonaldehyde and acetaldehyde on cultured mammalian cells. Production of micronuclei and chromosomal aberrations.
Topics: Acetaldehyde; Animals; Cell Nucleus; Cells, Cultured; Chromosome Aberrations; Dose-Response Relation | 1982 |
Influence of chronic ethanol uptake and acute acetaldehyde treatment on the chromosomes of bone-marrow cells and peripheral lymphocytes of Chinese hamsters.
Topics: Acetaldehyde; Alcoholism; Animals; Bone Marrow; Chromosome Aberrations; Chromosomes; Cricetinae; Cri | 1981 |
Cytogenetic effects of 2-methoxyethanol and its metabolite, methoxyacetaldehyde, in mammalian cells in vitro.
Topics: Acetaldehyde; Animals; CHO Cells; Chromosome Aberrations; Cricetinae; Dose-Response Relationship, Dr | 1994 |
Evaluation of the clastogenic effects of 2-methoxyethanol in mice.
Topics: Acetaldehyde; Animals; Bone Marrow; Chromosome Aberrations; Ethylene Glycols; Male; Mice; Mice, Inbr | 1993 |
Effects of reactive oxygen species (ROS) modulators, TEMPOL and catalase, on methoxyacetaldehyde (MALD) -induced chromosome aberrations in Chinese hamster ovary (CHO)-AS52 cells.
Topics: Acetaldehyde; Animals; Catalase; CHO Cells; Chromosome Aberrations; Cricetinae; Cyclic N-Oxides; DNA | 1996 |
Induction of chromosomal aberrations in peripheral lymphocytes of human blood in vitro, and of SCEs in bone-marrow cells of mice in vivo by ethanol and its metabolite acetaldehyde.
Topics: Acetaldehyde; Animals; Bone Marrow; Bromodeoxyuridine; Chromosome Aberrations; Crossing Over, Geneti | 1979 |
[Effect of ethanol and its metabolite acetaldehyde on the chromosomal apparatus of rat and human cells].
Topics: Acetaldehyde; Adult; Alcoholism; Aneuploidy; Animals; Chromosome Aberrations; Ethanol; Humans; Leuko | 1978 |
Ethanol and acetaldehyde potentiate the clastogenicity of ultraviolet light, methyl methanesulfonate, mitomycin C and bleomycin in Chinese hamster ovary cells.
Topics: Acetaldehyde; Animals; Bleomycin; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Drug Sy | 1989 |
Development of techniques to study induction of aneuploidy in somatic cells in vitro and in vivo.
Topics: Acetaldehyde; Aneuploidy; Animals; Chromosome Aberrations; Cricetinae; Cricetulus; Demecolcine; Diet | 1989 |
Effects of caffeine and inhibitors of DNA synthesis on chromatid-type aberrations induced by acetaldehyde in root-tip cells.
Topics: Acetaldehyde; Caffeine; Cells, Cultured; Chromatids; Chromosome Aberrations; Cytarabine; DNA Replica | 1987 |
DNA and chromosome damage induced by acetaldehyde in human lymphocytes in vitro.
Topics: Acetaldehyde; Alcohol Drinking; Chromosome Aberrations; DNA Damage; Environmental Exposure; Humans; | 1988 |
Chromosome damage induced by vinyl acetate through in vitro formation of acetaldehyde in human lymphocytes and Chinese hamster ovary cells.
Topics: Acetaldehyde; Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; DNA; Female; | 1985 |