acenocoumarol and Puerperal-Disorders

Topics: Acenocoumarol; Adult; Clinical Trials as Topic; Female; Genital Diseases, Female; Humans; Pregnancy; Pregnancy Complications; Puerperal Disorders; Thrombosis

Venous thromboembolism is an important cause for maternal morbidity and mortality in postpartum period. Though catheter-directed thrombolysis (CDT) is now considered as a safe and effective therapy for the management of deep venous thrombosis (DVT) but still it is not indicated in postpartum DVT. We are presenting a case of 22-year-old female patient who presented with post-partum lower limb DVT and managed successfully with CDT by using injection streptokinase and temporary inferior vena caval filter was inserted as prophylactic for pulmonary embolism as she had extensive DVT extending into inferior vena cava (IVC). During follow-up, she developed large skin necrosis in left lower limb which was managed by adding injection low-molecular-weight heparin. IVC filter also could not be retrieved even after trying all manoeuvres during follow-up after 2 weeks.

Topics: Acenocoumarol; Anticoagulants; Catheterization, Peripheral; Female; Fibrinolytic Agents; Humans; Lower Extremity; Necrosis; Puerperal Disorders; Skin; Streptokinase; Vena Cava Filters; Venous Thrombosis; Young Adult

We report the case of a 26 year-old woman who developed acquired hemophilia secondary to factor VIII inhibitors, two months after a normal pregnancy. The initial hemorrhagic event was a spontaneous deep muscular hematoma mimicking a deep venous thrombosis. This observation was marqued by the apparition of antibodies against porcin factor VIII under treatment by porcin factor VIII. Intravenous immunoglobulin was ineffective, then cyclophosphamide was necessary to control the disease.

Topics: Acenocoumarol; Adult; Anticoagulants; Blood Coagulation Tests; Diagnosis, Differential; Factor VIII; Female; Hemophilia A; Heparin; Humans; Pregnancy; Puerperal Disorders; Recurrence

A 34-year-old woman was admitted on the 10th day post partum complaining of loss of strength in the left arm and headache. The next day she started having seizures. Although the clinical picture suggested sinus thrombosis, initially a CT scan showed no abnormalities. The diagnosis of sinus sagittalis superior thrombosis was finally made by means of arteriography. The patient was treated successfully with anticoagulants and recovered without sequelae.

Topics: Acenocoumarol; Adult; Cerebral Angiography; Female; Humans; Pregnancy; Puerperal Disorders; Sinus Thrombosis, Intracranial; Tomography, X-Ray Computed