acenocoumarol and Eye-Diseases

The outcome of 50 surgical procedures in 41 patients who were anticoagulated at the time of surgery were reviewed to determine whether anticoagulation was associated with an increase in ophthalmic morbidity. Twenty-seven patients were receiving warfarin and 14 patients nicoumalone. The International Normalised Ratio (INR) was determined immediately prior to surgery and ranged from 1.1 to 4.9. Thirty-nine operations were performed under local anaesthetic and 11 under general anaesthetic. Thirty-three patients had extracapsular cataract extractions with posterior chamber lens implantation. No major haemorrhagic complications were associated with the local anaesthetic or the surgical procedure. Patients on anticoagulation therapy are at risk of life-threatening complications if their anticoagulation is stopped or reduced. This study demonstrates that most ophthalmic surgical procedures can be safely performed whilst the patient is therapeutically anticoagulated.

Topics: Acenocoumarol; Anticoagulants; Blood Loss, Surgical; Eye Diseases; Humans; Intraoperative Care; Prospective Studies; Thromboembolism; Warfarin

Topics: Acenocoumarol; Anticoagulants; Coumarins; Eye Diseases; Factor V; Factor VII; Factor X; Hemorrhage; Hemostasis; Heparin; Humans; Phlebitis; Prothrombin Time; Retinal Hemorrhage; Vitamin K; Vitreous Body

Topics: Acenocoumarol; Eye Diseases; Humans; Lipopolysaccharides; Retinal Vessels; Thrombophlebitis