acenocoumarol and Cholestasis

acenocoumarol has been researched along with Cholestasis* in 2 studies

Trials

1 trial(s) available for acenocoumarol and Cholestasis

Article	Year
Pharmacokinetics of low molecular weight dermatan sulphate (desmin) in different cohorts of patients. Thrombosis research, 1998, May-01, Volume: 90, Issue:3 Topics: Acenocoumarol; Adult; Cholestasis; Chromogenic Compounds; Cohort Studies; Desmin; Factor Xa; Humans; Liver Diseases; Middle Aged; Partial Thromboplastin Time; Peptic Ulcer; Prothrombin; Thrombin Time; Thrombosis	1998

Other Studies

1 other study(ies) available for acenocoumarol and Cholestasis

Article	Year
Repeated occurrence of skin necrosis twice following coumarin intake and subsequently during decrease of vitamin K dependent coagulation factors associated with cholestasis. Thrombosis and haemostasis, 1982, Dec-27, Volume: 48, Issue:3 A female patient is described who developed skin and subcutaneous fat necrosis on two occasions after intake of acenocoumarol. Several months later identical skin changes occurred during an episode of cholestasis associated with a prolongation of the prothrombin time to an extent comparable with therapeutic anticoagulation; intake of oral anticoagulants could be excluded. This association gives new insights in the pathogenetic mechanisms responsible for the so-called coumarin necrosis and indicates that it may be not due to drug toxicity or allergy. Topics: Acenocoumarol; Adipose Tissue; Adult; Blood Coagulation Factors; Cholestasis; Drug Therapy, Combination; Female; Heparin; Humans; Necrosis; Recurrence; Skin Diseases; Thrombophlebitis; Vitamin K	1982

Article

Year

Repeated occurrence of skin necrosis twice following coumarin intake and subsequently during decrease of vitamin K dependent coagulation factors associated with cholestasis.

Thrombosis and haemostasis, 1982, Dec-27, Volume: 48, Issue:3

A female patient is described who developed skin and subcutaneous fat necrosis on two occasions after intake of acenocoumarol. Several months later identical skin changes occurred during an episode of cholestasis associated with a prolongation of the prothrombin time to an extent comparable with therapeutic anticoagulation; intake of oral anticoagulants could be excluded. This association gives new insights in the pathogenetic mechanisms responsible for the so-called coumarin necrosis and indicates that it may be not due to drug toxicity or allergy.

Topics: Acenocoumarol; Adipose Tissue; Adult; Blood Coagulation Factors; Cholestasis; Drug Therapy, Combination; Female; Heparin; Humans; Necrosis; Recurrence; Skin Diseases; Thrombophlebitis; Vitamin K

1982